anti-TRAF6 (TRAF6) Antikörper

Auf www.antikoerper-online.de finden Sie aktuell 157 TNF Receptor-Associated Factor 6 (TRAF6) Antikörper von 31 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TRAF6 Kits (19) und TRAF6 Proteine (14) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 210 TRAF6 Produkte verfügbar.
Synonyme:
2310003F17Rik, AI851288, C630032O20Rik, CG10961, Dmel\\CG10961, dtraf2, dTRAF6, fi15f02, GB10539, MGC:3310, RNF85, TRAF, Traf2, TRAF6, wu:fi15f02, xtraf6, zgc:63704
Alle Antikörper anzeigen Gen GeneID UniProt
TRAF6 22034 P70196
TRAF6 7189 Q9Y4K3
TRAF6 311245 B5DF45

Meistgesuchte Reaktivitäten zu anti-TRAF6 (TRAF6) Antikörper

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Weitere Antikörper gegen TRAF6 Interaktionspartner

Fruit Fly (Drosophila melanogaster) TNF Receptor-Associated Factor 6 (TRAF6) Interaktionspartner

  1. we found that reactive oxygen species-induced autophagy acts as a negative feedback regulator of JNK (zeige MAPK8 Antikörper) activity by dissociating Atg9 (zeige ATG9A Antikörper)/mAtg9 (zeige ATG9A Antikörper) from dTRAF2/TRAF6 in Drosophila.

  2. null mutant of DTRAF2 showed immune deficiencies in which NF-kappaB nuclear translocation and antimicrobial gene transcription against microbial infection were severely impaired

Mouse (Murine) TNF Receptor-Associated Factor 6 (TRAF6) Interaktionspartner

  1. work reveals that simulated microgravity promotes the apoptotic response through a combined modulation of the Uev1A/TICAM/TRAF (zeige TRAF1 Antikörper)/NF-kappaB (zeige NFKB1 Antikörper)-regulated apoptosis and the p53 (zeige TP53 Antikörper)/PCNA (zeige PCNA Antikörper)- and ATM (zeige ATM Antikörper)/ATR (zeige ATR Antikörper)-Chk1 (zeige CHEK1 Antikörper)/2-controlled DNA-damage response pathways.

  2. TRAF6 prevents the mitochondrial translocation of p53 (zeige TP53 Antikörper) and spontaneous apoptosis by promoting lysine63-linked ubiquitination of p53 (zeige TP53 Antikörper) in cytosol.

  3. TRAF6 mediates lysine-63 ubiquitination within the SH2 (zeige MYO15 Antikörper) domain of STAT3 (zeige STAT3 Antikörper), which is an essential step for STAT3 (zeige STAT3 Antikörper) membrane recruitment and phosphorylation in response to S Typhimurium infection; results reveal a strategy in which S Typhimurium T3SS effectors broaden their functions through the activation of host proteins in a ubiquitination-dependent manner to manipulate host cells into becoming a Salmonella-friendly zone

  4. this study shows that an interaction of TRAF6 with cullin-5 (zeige CUL5 Antikörper) promotes TRAF6 polyubiquitination and lipopolysaccharide signaling

  5. Consistent with cellular studies, icaritin downregulated TRAF6 and NFATc1 protein expression in CD11b(+) /Gr-1(-/low) osteoclast precursors

  6. Data (including data from studies using knockout mice) suggest that RANKL (zeige TNFSF11 Antikörper) enhances TNF (zeige TNF Antikörper)-induced osteoclast formation from precursor spleen cells and enhances bone resorption independently of Traf6 by degrading Traf3 (zeige TRAF3 Antikörper), a known inhibitor of osteoclastogenesis. (RANKL (zeige TNFSF11 Antikörper) = osteoclast differentiation factor (zeige TNFSF11 Antikörper); TNF (zeige TNF Antikörper) = tumor necrosis factor (zeige TNF Antikörper); Traf (zeige TRAF1 Antikörper) = TNF (zeige TNF Antikörper) receptor-associated factor)

  7. the SH3 domain (zeige ITSN1 Antikörper) of NOSTRIN (zeige NOSTRIN Antikörper) is involved in the NOSTRIN (zeige NOSTRIN Antikörper)-TRAF6 interaction and is required for NOSTRIN (zeige NOSTRIN Antikörper)-induced down-regulation of endothelial cell proteins

  8. this study shows that TRAF6 overexpression in hematopoietic stem/progenitor cells results in impaired hematopoiesis and bone marrow failure

  9. TRAF6 and H2AX (zeige H2AFX Antikörper) overexpression and gammaH2AX (zeige H2AFX Antikörper)-mediated HIF1alpha (zeige HIF1A Antikörper) enrichment in the nucleus of cancer cells lead to overactivation of HIF1alpha (zeige HIF1A Antikörper)-driven tumorigenesis, glycolysis and metastasis.

  10. By studying the response of T (zeige IFT122 Antikörper)raf6(+/+) and Traf6(-/-)mouse embryonic fibroblasts to S. typhimurium infection, this study showed that TRAF6 promoted apoptosis by increasing reactive oxygen species accumulation, which led to increased Bax/Bcl-2 ratio, Bax recruitment to mitochondrial membrane, and release of Cyt c into the cytoplasm.

Zebrafish TNF Receptor-Associated Factor 6 (TRAF6) Interaktionspartner

  1. we have now analyzed the in vivo function of Traf6 in the innate immune response without interference of adaptive immunity

  2. Full-length traf6 was functionally characterized.

Human TNF Receptor-Associated Factor 6 (TRAF6) Interaktionspartner

  1. TRAF6 prevents the mitochondrial translocation of p53 (zeige TP53 Antikörper) and spontaneous apoptosis by promoting lysine63-linked ubiquitination of p53 (zeige TP53 Antikörper) in cytosol.

  2. The E3 ligase TRAF6 binds to DCP1a (zeige DCP1A Antikörper) and indirectly regulates DCP1a (zeige DCP1A Antikörper) phosphorylation, expression of decapping factors, and gene-specific mRNA decay.

  3. Study showed that patients without a history of atrial fibrillation who develop postoperative atrial fibrillation have a higher percentage of left atrial fibrosis, increased expression of TRAF6, higher serum Ang II (zeige AGT Antikörper) levels, and changes in the activities of the MAPKs/TGF-beta1 (zeige TGFB1 Antikörper)/TRAF6 pathway.

  4. Low TRAF6 expression is associated with graft-versus-host disease.

  5. Consistent with cellular studies, icaritin downregulated TRAF6 and NFATc1 protein expression in CD11b(+) /Gr-1(-/low) osteoclast precursors

  6. Results suggest that overexpression of miR (zeige MLXIP Antikörper)-146a could promote IDD (zeige COL9A3 Antikörper) through the TRAF (zeige TRAF1 Antikörper)/NF-kappaB (zeige NFKB1 Antikörper) pathway.

  7. TRAF6 and H2AX (zeige H2AFX Antikörper) overexpression and gammaH2AX (zeige H2AFX Antikörper)-mediated HIF1alpha (zeige HIF1A Antikörper) enrichment in the nucleus of cancer cells lead to overactivation of HIF1alpha (zeige HIF1A Antikörper)-driven tumorigenesis, glycolysis and metastasis.

  8. These findings show that SopB (zeige IFT122 Antikörper) suppresses host cell apoptosis by binding to TRAF6 and preventing mitochondrial reactive oxygen species generation.

  9. HCV infection suppressed the host innate immune response through the induction of autophagic degradation of TRAF6. This finding provided important information for further understanding how HCV evades host immunity to establish persistence

  10. Vav3 (zeige VAV3 Antikörper) is a novel TRAF6 interaction partner that functions in the activation of cooperative signaling between T6BSs and the IVVY motif in the RANK signaling complex.

TRAF6 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from, members of the TNF receptor superfamily. This protein mediates signaling from members of the TNF receptor superfamily as well as the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. This protein also interacts with the transforming growth factor (TGF) beta receptor complex and is required for Smad-independent activation of the JNK and p38 kinases. This protein has an amino terminal RING domain which is followed by four zinc-finger motifs, a central coiled-coil region and a highly conserved carboxyl terminal domain, known as the TRAF-C domain. Two alternatively spliced transcript variants, encoding an identical protein, have been reported.

Alternative names and synonyms associated with TRAF6

  • TNF receptor-associated factor 6, E3 ubiquitin protein ligase (traf6-b) Antikörper
  • TNF-receptor-associated factor 6 (Traf6) Antikörper
  • TNF receptor-associated factor 6 (TRAF6) Antikörper
  • TNF receptor-associated factor 6, E3 ubiquitin protein ligase (traf6) Antikörper
  • TNF receptor-associated factor 6 (traf6) Antikörper
  • TNF receptor-associated factor 6 (Traf6) Antikörper
  • TNF receptor-associated factor 6, E3 ubiquitin protein ligase (TRAF6) Antikörper
  • TNF receptor-associated factor 6, E3 ubiquitin protein ligase (Traf6) Antikörper
  • 2310003F17Rik Antikörper
  • AI851288 Antikörper
  • C630032O20Rik Antikörper
  • CG10961 Antikörper
  • Dmel\\CG10961 Antikörper
  • dtraf2 Antikörper
  • dTRAF6 Antikörper
  • fi15f02 Antikörper
  • GB10539 Antikörper
  • MGC:3310 Antikörper
  • RNF85 Antikörper
  • TRAF Antikörper
  • Traf2 Antikörper
  • TRAF6 Antikörper
  • wu:fi15f02 Antikörper
  • xtraf6 Antikörper
  • zgc:63704 Antikörper

Bezeichner auf Proteinebene für TRAF6

TNF receptor-associated factor 6-B , E3 ubiquitin-protein ligase TRAF6 , CG10961-PA , TNF-receptor-associated factor 2 , Traf6-PA , TNF receptor-associated factor 6 , TNF receptor-associated factor 6-like , RING finger protein 85 , interleukin-1 signal transducer , TNF-receptor associated factor 6

GENE ID SPEZIES
444777 Xenopus laevis
31746 Drosophila melanogaster
423163 Gallus gallus
451702 Pan troglodytes
493524 Xenopus (Silurana) tropicalis
551819 Apis mellifera
100010055 Monodelphis domestica
100174890 Gasterosteus aculeatus
100395364 Callithrix jacchus
100449432 Pongo abelii
100510771 Anolis carolinensis
100544809 Meleagris gallopavo
100595327 Nomascus leucogenys
22034 Mus musculus
539124 Bos taurus
554561 Danio rerio
7189 Homo sapiens
311245 Rattus norvegicus
100688110 Canis lupus familiaris
396629 Sus scrofa
716907 Macaca mulatta
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