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anti-TRAF6 (TRAF6) Antikörper

Bezeichnung:
anti-TNF Receptor-Associated Factor 6 Antikörper (TRAF6)
Auf www.antikoerper-online.de finden Sie aktuell 155 TNF Receptor-Associated Factor 6 (TRAF6) Antikörper von 30 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TRAF6 Kits (17) und TRAF6 Proteine (14) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 206 TRAF6 Produkte verfügbar.
Synonyme:
2310003F17Rik, AI851288, C630032O20Rik, CG10961, Dmel\\CG10961, dtraf2, dTRAF6, fi15f02, GB10539, MGC:3310, RNF85, TRAF, Traf2, TRAF6, wu:fi15f02, xtraf6, zgc:63704

Meistgesuchte Reaktivitäten zu anti-TRAF6 (TRAF6) Antikörper

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anti-Mouse (Murine) TRAF6 Antikörper:

anti-Human TRAF6 Antikörper:

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Am meisten referenzierte anti-TRAF6 Antikörper

  1. Human Polyclonal TRAF6 Primary Antibody für WB - ABIN1881900 : Hinz, Stilmann, Arslan, Khanna, Dittmar, Scheidereit: A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation. in Molecular cell 2010 (PubMed)
    Zeige alle 4 Referenzen für ABIN1881900

  2. Cow (Bovine) Polyclonal TRAF6 Primary Antibody für WB - ABIN2779305 : Jazdzewski, Murray, Franssila, Jarzab, Schoenberg, de la Chapelle: Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinoma. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

  3. Human Polyclonal TRAF6 Primary Antibody für EIA, IF - ABIN501028 : Takeda, Kaisho, Akira: Toll-like receptors. in Annual review of immunology 2003 (PubMed)

Weitere Antikörper gegen TRAF6 Interaktionspartner

Fruit Fly (Drosophila melanogaster) TNF Receptor-Associated Factor 6 (TRAF6) Interaktionspartner

  1. we found that reactive oxygen species-induced autophagy acts as a negative feedback regulator of JNK (zeige MAPK8 Antikörper) activity by dissociating Atg9 (zeige ATG9A Antikörper)/mAtg9 (zeige ATG9A Antikörper) from dTRAF2/TRAF6 in Drosophila.

  2. null mutant of DTRAF2 showed immune deficiencies in which NF-kappaB nuclear translocation and antimicrobial gene transcription against microbial infection were severely impaired

Mouse (Murine) TNF Receptor-Associated Factor 6 (TRAF6) Interaktionspartner

  1. the SH3 domain (zeige ITSN1 Antikörper) of NOSTRIN (zeige NOSTRIN Antikörper) is involved in the NOSTRIN (zeige NOSTRIN Antikörper)-TRAF6 interaction and is required for NOSTRIN (zeige NOSTRIN Antikörper)-induced down-regulation of endothelial cell proteins

  2. this study shows that TRAF6 overexpression in hematopoietic stem/progenitor cells results in impaired hematopoiesis and bone marrow failure

  3. TRAF6 and H2AX (zeige H2AFX Antikörper) overexpression and gammaH2AX (zeige H2AFX Antikörper)-mediated HIF1alpha (zeige HIF1A Antikörper) enrichment in the nucleus of cancer cells lead to overactivation of HIF1alpha (zeige HIF1A Antikörper)-driven tumorigenesis, glycolysis and metastasis.

  4. By studying the response of T (zeige IFT122 Antikörper)raf6(+/+) and Traf6(-/-)mouse embryonic fibroblasts to S. typhimurium infection, this study showed that TRAF6 promoted apoptosis by increasing reactive oxygen species accumulation, which led to increased Bax/Bcl-2 ratio, Bax recruitment to mitochondrial membrane, and release of Cyt c into the cytoplasm.

  5. BAT3 (zeige BAT3 Antikörper) negatively regulates lipopolysaccharide-induced NF-kappaB (zeige NFKB1 Antikörper) signaling through TRAF6.

  6. these data identify Trim13 (zeige TRIM13 Antikörper) as a positive regulator of NF-kappaB (zeige NFKB1 Antikörper) activation and suggest that lysine 29-linked polyubiquitination is a specific ubiquitin-linked pattern involved in the control of TLR2 (zeige TLR2 Antikörper) signaling.

  7. this study shows that the absence TRAF6 expression by dendritic cells leads to spontaneous generation of Th2-associated immune responses and increased susceptibility to model antigen-induced asthma

  8. MiR (zeige MLXIP Antikörper)-144 reduces the antiviral response by attenuating the TRAF6-IRF7 (zeige IRF7 Antikörper) pathway to alter the cellular antiviral transcriptional landscape.

  9. Data indicate a role of microRNA miR (zeige MLXIP Antikörper)-146a in the modulation of host defense against mycobacterial infection by repressing nitric oxide (NO) production via targeting tumor necrosis factor (TNF (zeige TNF Antikörper)) receptor-associated factor 6 (TRAF6), which may provide a promising therapeutic target for tuberculosis.

  10. CD137 (zeige TNFRSF9 Antikörper) Regulates NFATc1 (zeige NFATC1 Antikörper) Expression in Mouse VSMCs through TRAF6/NF-kappaB (zeige NFKB1 Antikörper) p65 (zeige NFkBP65 Antikörper) Signaling Pathway.

Zebrafish TNF Receptor-Associated Factor 6 (TRAF6) Interaktionspartner

  1. we have now analyzed the in vivo function of Traf6 in the innate immune response without interference of adaptive immunity

  2. Full-length traf6 was functionally characterized.

Human TNF Receptor-Associated Factor 6 (TRAF6) Interaktionspartner

  1. Results suggest that overexpression of miR (zeige MLXIP Antikörper)-146a could promote IDD (zeige COL9A3 Antikörper) through the TRAF (zeige TRAF1 Antikörper)/NF-kappaB (zeige NFKB1 Antikörper) pathway.

  2. TRAF6 and H2AX (zeige H2AFX Antikörper) overexpression and gammaH2AX (zeige H2AFX Antikörper)-mediated HIF1alpha (zeige HIF1A Antikörper) enrichment in the nucleus of cancer cells lead to overactivation of HIF1alpha (zeige HIF1A Antikörper)-driven tumorigenesis, glycolysis and metastasis.

  3. These findings show that SopB (zeige IFT122 Antikörper) suppresses host cell apoptosis by binding to TRAF6 and preventing mitochondrial reactive oxygen species generation.

  4. HCV infection suppressed the host innate immune response through the induction of autophagic degradation of TRAF6. This finding provided important information for further understanding how HCV evades host immunity to establish persistence

  5. Vav3 (zeige VAV3 Antikörper) is a novel TRAF6 interaction partner that functions in the activation of cooperative signaling between T6BSs and the IVVY motif in the RANK signaling complex.

  6. TRAF6 expression was decreased in tympanic membrane of otitis media patients.

  7. Peripheral blood levels of S100A8 (zeige S100A8 Antikörper) and TRAF6 in SAE patients were elevated and might be related to the severity of SAE and predict the outcome of SAE.

  8. Low TRAF6 expression is associated with Graves' disease.

  9. MiR (zeige MLXIP Antikörper)-146a regulates inflammatory macrophage infiltration in Polymyositis/Dermatomyositis by targeting TRAF6 and affecting the IL-17 (zeige IL17A Antikörper)/ICAM-1 (zeige ICAM1 Antikörper) pathway.

  10. Study demonstrates that TRAF6 is upregulated in human lung cancer cells, and siRNA-induced TRAF6 knockdown inhibits the invasion of lung cancer cells and promotes apoptosis.

TRAF6 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from, members of the TNF receptor superfamily. This protein mediates signaling from members of the TNF receptor superfamily as well as the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. This protein also interacts with the transforming growth factor (TGF) beta receptor complex and is required for Smad-independent activation of the JNK and p38 kinases. This protein has an amino terminal RING domain which is followed by four zinc-finger motifs, a central coiled-coil region and a highly conserved carboxyl terminal domain, known as the TRAF-C domain. Two alternatively spliced transcript variants, encoding an identical protein, have been reported.

Alternative names and synonyms associated with TRAF6

  • TNF receptor-associated factor 6, E3 ubiquitin protein ligase (traf6-b) Antikörper
  • TNF-receptor-associated factor 6 (Traf6) Antikörper
  • TNF receptor-associated factor 6 (TRAF6) Antikörper
  • TNF receptor-associated factor 6, E3 ubiquitin protein ligase (traf6) Antikörper
  • TNF receptor-associated factor 6 (traf6) Antikörper
  • TNF receptor-associated factor 6 (Traf6) Antikörper
  • TNF receptor-associated factor 6, E3 ubiquitin protein ligase (TRAF6) Antikörper
  • TNF receptor-associated factor 6, E3 ubiquitin protein ligase (Traf6) Antikörper
  • 2310003F17Rik Antikörper
  • AI851288 Antikörper
  • C630032O20Rik Antikörper
  • CG10961 Antikörper
  • Dmel\\CG10961 Antikörper
  • dtraf2 Antikörper
  • dTRAF6 Antikörper
  • fi15f02 Antikörper
  • GB10539 Antikörper
  • MGC:3310 Antikörper
  • RNF85 Antikörper
  • TRAF Antikörper
  • Traf2 Antikörper
  • TRAF6 Antikörper
  • wu:fi15f02 Antikörper
  • xtraf6 Antikörper
  • zgc:63704 Antikörper

Bezeichner auf Proteinebene für TRAF6

TNF receptor-associated factor 6-B , E3 ubiquitin-protein ligase TRAF6 , CG10961-PA , TNF-receptor-associated factor 2 , Traf6-PA , TNF receptor-associated factor 6 , TNF receptor-associated factor 6-like , RING finger protein 85 , interleukin-1 signal transducer , TNF-receptor associated factor 6

GENE ID SPEZIES
444777 Xenopus laevis
31746 Drosophila melanogaster
423163 Gallus gallus
451702 Pan troglodytes
493524 Xenopus (Silurana) tropicalis
551819 Apis mellifera
100010055 Monodelphis domestica
100174890 Gasterosteus aculeatus
100395364 Callithrix jacchus
100449432 Pongo abelii
100510771 Anolis carolinensis
100544809 Meleagris gallopavo
100595327 Nomascus leucogenys
22034 Mus musculus
539124 Bos taurus
554561 Danio rerio
7189 Homo sapiens
311245 Rattus norvegicus
100688110 Canis lupus familiaris
396629 Sus scrofa
716907 Macaca mulatta
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