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anti-TRAF6 (TRAF6) Antikörper

anti-TNF Receptor-Associated Factor 6 Antikörper (TRAF6)
Auf finden Sie aktuell 148 TNF Receptor-Associated Factor 6 (TRAF6) Antikörper von 29 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TRAF6 Kits (13) und TRAF6 Proteine (10) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 191 TRAF6 Produkte verfügbar.
2310003F17Rik, AI851288, C630032O20Rik, CG10961, Dmel\\CG10961, dtraf2, dTRAF6, fi15f02, GB10539, MGC:3310, RNF85, TRAF, Traf2, TRAF6, wu:fi15f02, xtraf6, zgc:63704

Meistgesuchte Reaktivitäten zu anti-TRAF6 (TRAF6) Antikörper

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anti-Mouse (Murine) TRAF6 Antikörper:

anti-Human TRAF6 Antikörper:

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Am meisten referenzierte anti-TRAF6 Antikörper

  1. Human Polyclonal TRAF6 Primary Antibody für WB - ABIN1881900 : Hinz, Stilmann, Arslan, Khanna, Dittmar, Scheidereit: A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation. in Molecular cell 2010 (PubMed)
    Zeige alle 4 Referenzen für ABIN1881900

  2. Cow (Bovine) Polyclonal TRAF6 Primary Antibody für WB - ABIN2779305 : Jazdzewski, Murray, Franssila, Jarzab, Schoenberg, de la Chapelle: Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinoma. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

  3. Human Polyclonal TRAF6 Primary Antibody für EIA, IF - ABIN501028 : Takeda, Kaisho, Akira: Toll-like receptors. in Annual review of immunology 2003 (PubMed)

Weitere Antikörper gegen TRAF6 Interaktionspartner

Fruit Fly (Drosophila melanogaster) TNF Receptor-Associated Factor 6 (TRAF6) Interaktionspartner

  1. we found that reactive oxygen species-induced autophagy acts as a negative feedback regulator of JNK (zeige MAPK8 Antikörper) activity by dissociating Atg9 (zeige ATG9A Antikörper)/mAtg9 (zeige ATG9A Antikörper) from dTRAF2/TRAF6 in Drosophila.

  2. null mutant of DTRAF2 showed immune deficiencies in which NF-kappaB nuclear translocation and antimicrobial gene transcription against microbial infection were severely impaired

Mouse (Murine) TNF Receptor-Associated Factor 6 (TRAF6) Interaktionspartner

  1. Data indicate a role of microRNA miR (zeige MLXIP Antikörper)-146a in the modulation of host defense against mycobacterial infection by repressing nitric oxide (NO) production via targeting tumor necrosis factor (TNF (zeige TNF Antikörper)) receptor-associated factor 6 (TRAF6), which may provide a promising therapeutic target for tuberculosis.

  2. CD137 (zeige TNFRSF9 Antikörper) Regulates NFATc1 (zeige NFATC1 Antikörper) Expression in Mouse VSMCs through TRAF6/NF-kappaB (zeige NFKB1 Antikörper) p65 (zeige NFkBP65 Antikörper) Signaling Pathway.

  3. TRAF6 was required for the activation of MAPKs ERK1/2 (zeige MAPK1/3 Antikörper) and JNK1 (zeige MAPK8 Antikörper)/2

  4. Results suggest that microRNA-146a-5p attenuates neuropathic pain partly through inhibition of tumor necrosis factor (zeige TNF Antikörper) receptor associated factor-6 and its downstream c-jun N-terminal kinase/CCL2 (zeige CCL2 Antikörper) signaling.

  5. we demonstrate that CpG treatment leads to ubiquitin-mediated degradation of DOK3 (zeige DOK3 Antikörper) via interaction with an E3 ligase TNFR (zeige TNFRSF1A Antikörper)-associated factor 6 (TRAF6).

  6. TRAF6 is determined to be a direct E3 ligase for GSK3beta (zeige GSK3b Antikörper), and TRAF6-mediated GSK3beta (zeige GSK3b Antikörper) ubiquitination is essential for poly I:C-dependent cytokine production by promoting the TLR3 (zeige TLR3 Antikörper) adaptor protein TRIF (zeige RNF138 Antikörper)-assembled signalling complex.

  7. TIFAB (zeige TIFAB Antikörper) loss increases TRAF6 protein and the dynamic range of TLR4 (zeige TLR4 Antikörper) signaling

  8. The MYSM1 (zeige MYSM1 Antikörper) SWIRM domain interacts with TRAF6 to terminate PRR (zeige PVRL1 Antikörper) pathways for pro-inflammatory and type I interferon (zeige IFNA Antikörper) responses.

  9. Transmembrane motif T6BM2-mediated TRAF6 binding is required for MAVS (zeige MAVS Antikörper)-related antiviral response.

  10. Data show that the degradation of TNF receptor-associated factor 3 (TRAF3 (zeige TRAF3 Antikörper)) and TNF (zeige TNF Antikörper) receptor-associated Ffactor 6 (TRAF6) was accelerated in ubiquitin-specific protease 25 (zeige USP25 Antikörper) knockout (USP25 (zeige USP25 Antikörper)-/-) cells after viral infection.

Zebrafish TNF Receptor-Associated Factor 6 (TRAF6) Interaktionspartner

  1. we have now analyzed the in vivo function of Traf6 in the innate immune response without interference of adaptive immunity

  2. Full-length traf6 was functionally characterized.

Human TNF Receptor-Associated Factor 6 (TRAF6) Interaktionspartner

  1. Low TRAF6 expression is associated with Graves' disease.

  2. MiR (zeige MLXIP Antikörper)-146a regulates inflammatory macrophage infiltration in Polymyositis/Dermatomyositis by targeting TRAF6 and affecting the IL-17 (zeige IL17A Antikörper)/ICAM-1 (zeige ICAM1 Antikörper) pathway.

  3. Study demonstrates that TRAF6 is upregulated in human lung cancer cells, and siRNA-induced TRAF6 knockdown inhibits the invasion of lung cancer cells and promotes apoptosis.

  4. High TRAF6 expression is associated with melanoma invasion and metastasis.

  5. The expression of TRAF6 was positively correlated with an advanced N stage and acted as a predictor of a poor prognosis in patients with gastric cancer

  6. DK1 (zeige DOLK Antikörper) inhibits the formation of the TAK1 (zeige MAP3K7 Antikörper)-TAB2 (zeige TAB2 Antikörper)-TRAF6 complex and leads to the inhibition of TRAF6 ubiquitination.

  7. DAT (zeige SLC6A3 Antikörper) stabilized IkBa (zeige NFKBIA Antikörper) by inhibiting the phosphorylation of Ika by the IkB (zeige NFKBIB Antikörper) kinase (IKK (zeige CHUK Antikörper)) complex. DAT (zeige SLC6A3 Antikörper) induced proteasomal degradation of TRAF6, and DAT (zeige SLC6A3 Antikörper) suppressed IKKb (zeige IKBKB Antikörper)-phosphorylation through downregulation of TRAF6

  8. TRAF6 may be involved in cell migration, invasion, and apoptosis of SPC (zeige UCN3 Antikörper)-A-1 cells, possibly through regulating the NF-B-CD24 (zeige CD24 Antikörper)/CXCR4 (zeige CXCR4 Antikörper) pathway..

  9. These findings suggest that RNF166 positively regulates RNA virus-triggered IFN-beta (zeige IFNB1 Antikörper) production by enhancing the ubiquitination of TRAF3 (zeige TRAF3 Antikörper) and TRAF6.

  10. In 816 matched pairs of Han Chinese with and without ischemic stroke, TRAF6 rs5030416 was associated with increased susceptibility in various genetic models. No association was found for rs5030411, although it was associated with total cholesterol.

TRAF6 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from, members of the TNF receptor superfamily. This protein mediates signaling from members of the TNF receptor superfamily as well as the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. This protein also interacts with the transforming growth factor (TGF) beta receptor complex and is required for Smad-independent activation of the JNK and p38 kinases. This protein has an amino terminal RING domain which is followed by four zinc-finger motifs, a central coiled-coil region and a highly conserved carboxyl terminal domain, known as the TRAF-C domain. Two alternatively spliced transcript variants, encoding an identical protein, have been reported.

Alternative names and synonyms associated with TRAF6

  • TNF receptor-associated factor 6, E3 ubiquitin protein ligase (traf6-b) Antikörper
  • TNF-receptor-associated factor 6 (Traf6) Antikörper
  • TNF receptor-associated factor 6 (TRAF6) Antikörper
  • TNF receptor-associated factor 6, E3 ubiquitin protein ligase (traf6) Antikörper
  • TNF receptor-associated factor 6 (traf6) Antikörper
  • TNF receptor-associated factor 6 (Traf6) Antikörper
  • TNF receptor-associated factor 6, E3 ubiquitin protein ligase (TRAF6) Antikörper
  • TNF receptor-associated factor 6, E3 ubiquitin protein ligase (Traf6) Antikörper
  • 2310003F17Rik Antikörper
  • AI851288 Antikörper
  • C630032O20Rik Antikörper
  • CG10961 Antikörper
  • Dmel\\CG10961 Antikörper
  • dtraf2 Antikörper
  • dTRAF6 Antikörper
  • fi15f02 Antikörper
  • GB10539 Antikörper
  • MGC:3310 Antikörper
  • RNF85 Antikörper
  • TRAF Antikörper
  • Traf2 Antikörper
  • TRAF6 Antikörper
  • wu:fi15f02 Antikörper
  • xtraf6 Antikörper
  • zgc:63704 Antikörper

Bezeichner auf Proteinebene für TRAF6

TNF receptor-associated factor 6-B , E3 ubiquitin-protein ligase TRAF6 , CG10961-PA , TNF-receptor-associated factor 2 , Traf6-PA , TNF receptor-associated factor 6 , TNF receptor-associated factor 6-like , RING finger protein 85 , interleukin-1 signal transducer , TNF-receptor associated factor 6

444777 Xenopus laevis
31746 Drosophila melanogaster
423163 Gallus gallus
451702 Pan troglodytes
493524 Xenopus (Silurana) tropicalis
551819 Apis mellifera
100010055 Monodelphis domestica
100174890 Gasterosteus aculeatus
100395364 Callithrix jacchus
100449432 Pongo abelii
100510771 Anolis carolinensis
100544809 Meleagris gallopavo
100595327 Nomascus leucogenys
22034 Mus musculus
539124 Bos taurus
554561 Danio rerio
7189 Homo sapiens
311245 Rattus norvegicus
100688110 Canis lupus familiaris
396629 Sus scrofa
716907 Macaca mulatta
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