anti-TRAF2 (TRAF2) Antikörper

anti-TNF Receptor-Associated Factor 2 Antikörper (TRAF2)
Auf finden Sie aktuell 200 TNF Receptor-Associated Factor 2 (TRAF2) Antikörper von 27 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TRAF2 Proteine (9) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 234 TRAF2 Produkte verfügbar.
AI325259, MGC:45012, TANK, TRAP, TRAP3
Alle Antikörper anzeigen Gen GeneID UniProt
TRAF2 7186 Q12933
TRAF2 22030 P39429
TRAF2 311786  

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Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-TRAF2 (TRAF2) Antikörper

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anti-Human TRAF2 Antikörper:

anti-Mouse (Murine) TRAF2 Antikörper:

anti-Rat (Rattus) TRAF2 Antikörper:

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Am meisten referenzierte anti-TRAF2 Antikörper

  1. Human Monoclonal TRAF2 Primary Antibody für WB - ABIN967631 : Arch, Gedrich, Thompson: Translocation of TRAF proteins regulates apoptotic threshold of cells. in Biochemical and biophysical research communications 2000 (PubMed)
    Zeige alle 7 Referenzen für 967631

  2. Human Polyclonal TRAF2 Primary Antibody für ICC, FACS - ABIN252172 : Döppler, Liou, Storz: Downregulation of TRAF2 mediates NIK-induced pancreatic cancer cell proliferation and tumorigenicity. in PLoS ONE 2013 (PubMed)
    Zeige alle 3 Referenzen für 252172

  3. Human Monoclonal TRAF2 Primary Antibody für IHC (p), IHC - ABIN252657 : van Galen, Muris, Giroth, Vos, Ossenkoppele, Meijer, Oudejans: Expression of TNF-receptor associated factor 2 correlates with poor progression-free survival time in ABC-like primary nodal diffuse large B-cell lymphomas. in Histopathology 2008 (PubMed)
    Zeige alle 3 Referenzen für 252657

  4. Human Monoclonal TRAF2 Primary Antibody für IF, WB - ABIN659110 : Alvarez, Harikumar, Hait, Allegood, Strub, Kim, Maceyka, Jiang, Luo, Kordula, Milstien, Spiegel: Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2. in Nature 2010 (PubMed)

  5. Human Polyclonal TRAF2 Primary Antibody für IF (p), IHC (p) - ABIN673479 : Lei, Bai, Yang, Lai, Qiu, Yang, Lian: Gsdma3 is a new factor needed for TNF-?-mediated apoptosis signal pathway in mouse skin keratinocytes. in Histochemistry and cell biology 2012 (PubMed)

  6. Human Polyclonal TRAF2 Primary Antibody für IHC, ELISA - ABIN190911 : Xu, Huang, Liu, Han: Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation. in The Journal of biological chemistry 2006 (PubMed)

Weitere Antikörper gegen TRAF2 Interaktionspartner

Human TNF Receptor-Associated Factor 2 (TRAF2) Interaktionspartner

  1. TRAF2 and OTUD7B (zeige OTUD7B Antikörper) govern a ubiquitin-dependent switch that regulates mTORC2 (zeige CRTC2 Antikörper) signalling

  2. destabilization of TRAF2 by miR-17 reduced the ability of TRAF2 to associate with cIAP2 (zeige BIRC3 Antikörper), resulting in the downregulation of TNF-alpha (zeige TNF Antikörper)-induced NF-kappaBp65, c-Jun (zeige JUN Antikörper), and STAT3 (zeige STAT3 Antikörper) nuclear translocation and the production of IL-6 (zeige IL6 Antikörper), IL-8 (zeige IL8 Antikörper), MMP-1 (zeige MMP1 Antikörper), and MMP-13 (zeige MMP13 Antikörper) in human rheumatoid arthritis synovial fibroblasts.

  3. HOXA1 (zeige HOXA1 Antikörper)-mediated activation of NF-kappaB (zeige NFKB1 Antikörper) is non-transcriptional and the RBCK1 (zeige RBCK1 Antikörper) and TRAF2 influences on NF-kappaB (zeige NFKB1 Antikörper) are epistatic to HOXA1 (zeige HOXA1 Antikörper)

  4. RIPK1 (zeige RIPK1 Antikörper) collaborates with TRAF2 to inhibit murine and human hepatocarcinogenesis.

  5. Data suggest that TRAF2 (TNF receptor-associated factor 2) negatively regulates (1) TNFR1- (tumor necrosis factor binding protein 1 (zeige TNFRSF1A Antikörper))-induced apoptosis, (2) TNFR2 (zeige TNFRSF1B Antikörper)- (tumor necrosis factor (zeige TNF Antikörper) receptor type 2)-induced non-canonical NFkappaB (zeige NFKB1 Antikörper) signaling, and (3) TNF- (tumor necrosis factor (zeige TNF Antikörper))-induced necroptosis. [REVIEW]

  6. Study presents the characterization of the peptide binding preferences of TRAFs 2, 3, and 5 using deep mutational scanning. The three TRAF (zeige TRAF1 Antikörper) proteins demonstrated different preferences for binding to members of the CD40 (zeige CD40 Antikörper) library, and three peptides from that library individually showed striking differences in affinity for the three TRAFs.

  7. The data demonstrate a novel and unexpected function of BIG1 (zeige CNTN3 Antikörper) that regulates TNFR1 (zeige TNFRSF1A Antikörper) signaling by targeting TRAF2.

  8. TRAF2 expression was increased in gastric cancer patients as a result of DNA hypomethylation.

  9. Data show that when death receptor 5 (DR5 (zeige TNFRSF10B Antikörper)) is suppressed, caspase-8 (zeige CASP8 Antikörper) may recruit and stabilize TNF receptor-associated factor 2 (TRAF2) to form a metastasis and invasion signaling complex, resulting in activation of ERK (zeige EPHB2 Antikörper) signaling.

  10. these findings reveal a novel mechanism by which TRAF2 mediates Lys63-linked ubiquitination of DUSP14 (zeige DUSP14 Antikörper), leading to DUSP14 (zeige DUSP14 Antikörper) activation in T cells

Mouse (Murine) TNF Receptor-Associated Factor 2 (TRAF2) Interaktionspartner

  1. work reveals that simulated microgravity promotes the apoptotic response through a combined modulation of the Uev1A/TICAM/TRAF (zeige TRAF1 Antikörper)/NF-kappaB (zeige NFKB1 Antikörper)-regulated apoptosis and the p53 (zeige TP53 Antikörper)/PCNA (zeige PCNA Antikörper)- and ATM (zeige ATM Antikörper)/ATR (zeige ATR Antikörper)-Chk1 (zeige CHEK1 Antikörper)/2-controlled DNA-damage response pathways.

  2. Traf2 mediates the pro-survival pathway in the heart by suppressing necroptotic signaling.

  3. Targeting TRAF2 may be useful as a therapeutic approach for immunosuppression-free islet allograft survival that avoids the thromboembolic complications associated with the use of anti-CD40L (zeige CD40LG Antikörper) antibodies.

  4. Celastrol promotes Nur77 (zeige NR4A1 Antikörper) migration from the nucleus to mitochondria, where it is ubiquitinated by TRAF2. Ubiquitinated Nur77 (zeige NR4A1 Antikörper) then interacts with p62/SQSTM1 (zeige SQSTM1 Antikörper), leading to autophagy of dysfunctional mitochondria and alleviation of inflammation.

  5. TRAF2 and OTUD7B (zeige OTUD7B Antikörper) govern a ubiquitin-dependent switch that regulates mTORC2 (zeige CRTC2 Antikörper) signalling

  6. this study shows that TRAF2 and TRAF5 (zeige TRAF5 Antikörper) work as important regulators of the IL-6R signaling needed for Th17 development

  7. Keratinocyte-specific deletion of Traf2, but not Sphk1 (zeige SPHK1 Antikörper) deficiency, disrupted TNF (zeige TNF Antikörper) mediated NF-kappaB (zeige NFKB1 Antikörper) and MAP kinase (zeige MAPK1 Antikörper) signalling and caused epidermal hyperplasia and psoriatic skin inflammation.

  8. TRAF2 functions as a key activator of MST1 (zeige MST1 Antikörper) in oxidative stress-induced (zeige SQSTM1 Antikörper) intracellular signaling processes.

  9. Proinflammatory TLR signalling is regulated by a TRAF2-dependent proteolysis mechanism in macrophages.

  10. NFkappaB anti-apoptotic target genes TNF receptor-associated factor 1 (TRAF1 (zeige TRAF1 Antikörper)), TNF receptor-associated factor 2 (TRAF2), cellular inhibitor of apoptosis (cIAP2 (zeige BIRC3 Antikörper)), and Ferritin heavy chain (FTH1 (zeige FTH1 Antikörper)) were increased following Losartan treatment

TRAF2 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined.

Alternative names and synonyms associated with TRAF2

  • TNF-receptor-associated factor 2 (Traf2) Antikörper
  • conjugal transfer protein TraF (traF2) Antikörper
  • TNF receptor-associated factor 2 (TRAF2) Antikörper
  • TNF receptor-associated factor 2 (Traf2) Antikörper
  • Tnf receptor-associated factor 2 (Traf2) Antikörper
  • AI325259 Antikörper
  • MGC:45012 Antikörper
  • TANK Antikörper
  • TRAP Antikörper
  • TRAP3 Antikörper

Bezeichner auf Proteinebene für TRAF2

GLEAN_07706 , conjugal transfer protein TraF , E3 ubiquitin-protein ligase TRAF2 , tumor necrosis factor type 2 receptor associated protein 3 , tumor necrosis factor type 2 receptor-associated protein 3 , TRAF family member-associated NFKB activator , TNF receptor-associated factor 2

661716 Tribolium castaneum
5816473 Bordetella petrii DSM 12804
10845633 Oligotropha carboxidovorans OM5
7186 Homo sapiens
480673 Canis lupus familiaris
512355 Bos taurus
22030 Mus musculus
311786 Rattus norvegicus
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