anti-TNFSF11 (TNFSF11) Antikörper

anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 Antikörper (TNFSF11)
Auf finden Sie aktuell 324 Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) Antikörper von 33 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TNFSF11 Kits (118) und TNFSF11 Proteine (75) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 534 TNFSF11 Produkte verfügbar.
BTF3L1, CD254, hRANKL2, HUMBTFB, Ly109l, OCIF, ODF, Opg, OPGL, OPTB2, RANKL, sOdf, TNFRSF11B, TNFSF11, Trance
Alle Antikörper anzeigen Gen GeneID UniProt
TNFSF11 690  
TNFSF11 21943 O35235
TNFSF11 117516 Q9ESE2

Alle Spezies anzeigen

Weitere Synonyme anzeigen

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Am meisten referenzierte anti-TNFSF11 Antikörper

  1. Human Monoclonal TNFSF11 Primary Antibody für ChIP, FACS - ABIN252476 : Kikuchi, Matsuguchi, Tsuboi, Mitani, Tanaka, Matsuoka, Yamamoto, Hishikawa, Noguchi, Yoshikai: Gene expression of osteoclast differentiation factor is induced by lipopolysaccharide in mouse osteoblasts via Toll-like receptors. in Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)
    Zeige alle 20 Referenzen für 252476

  2. Human Polyclonal TNFSF11 Primary Antibody für IF (p), IHC (p) - ABIN672696 : Yang, Li, Yang, Shen, Zou, Zhu, Zhang, Yang, Li: Efficacy and safety of echinacoside in a rat osteopenia model. in Evidence-based complementary and alternative medicine : eCAM 2013 (PubMed)
    Zeige alle 12 Referenzen für 672696

  3. Human Monoclonal TNFSF11 Primary Antibody für ChIP, CyTOF - ABIN252546 : Hsu, Lacey, Dunstan, Solovyev, Colombero, Timms, Tan, Elliott, Kelley, Sarosi, Wang, Xia, Elliott, Chiu, Black, Scully, Capparelli, Morony, Shimamoto, Bass, Boyle: Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand. in Proceedings of the National Academy of Sciences of the United States of America 1999 (PubMed)
    Zeige alle 10 Referenzen für 252546

  4. Human Polyclonal TNFSF11 Primary Antibody für IF (p), IHC (p) - ABIN668556 : Zhang, Liu, Li, Bai: Mycobacterium tuberculosis 10-kDa co-chaperonin regulates the expression levels of receptor activator of nuclear factor-?B ligand and osteoprotegerin in human osteoblasts. in Experimental and therapeutic medicine 2015 (PubMed)
    Zeige alle 9 Referenzen für 668556

  5. Human Monoclonal TNFSF11 Primary Antibody für ELISA - ABIN4249074 : Pearse, Sordillo, Yaccoby, Wong, Liau, Colman, Michaeli, Epstein, Choi: Multiple myeloma disrupts the TRANCE/ osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progression. in Proceedings of the National Academy of Sciences of the United States of America 2001 (PubMed)
    Zeige alle 9 Referenzen für 4249074

  6. Human Monoclonal TNFSF11 Primary Antibody für FACS, IHC (fro) - ABIN252684 : Yoneda, Ishimaru, Arakaki, Kobayashi, Izawa, Moriyama, Hayashi: Estrogen deficiency accelerates murine autoimmune arthritis associated with receptor activator of nuclear factor-kappa B ligand-mediated osteoclastogenesis. in Endocrinology 2004 (PubMed)
    Zeige alle 3 Referenzen für 252684

  7. Human Polyclonal TNFSF11 Primary Antibody für IF, ELISA - ABIN1533487 : Anderson, Maraskovsky, Billingsley, Dougall, Tometsko, Roux, Teepe, DuBose, Cosman, Galibert: A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. in Nature 1997 (PubMed)
    Zeige alle 2 Referenzen für 1533487

  8. Human Polyclonal TNFSF11 Primary Antibody für EIA, Func - ABIN116281 : Grimaud, Soubigou, Couillaud, Coipeau, Moreau, Passuti, Gouin, Redini, Heymann: Receptor activator of nuclear factor kappaB ligand (RANKL)/osteoprotegerin (OPG) ratio is increased in severe osteolysis. in The American journal of pathology 2003 (PubMed)

  9. Human Monoclonal TNFSF11 Primary Antibody für WB - ABIN2668631 : Hikita, Yana, Wakeyama, Nakamura, Kadono, Oshima, Nakamura, Seiki, Tanaka: Negative regulation of osteoclastogenesis by ectodomain shedding of receptor activator of NF-kappaB ligand. in The Journal of biological chemistry 2006 (PubMed)

Weitere Antikörper gegen TNFSF11 Interaktionspartner

Human Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) Interaktionspartner

  1. Correlations between sRANKL and IL-18 (zeige IL18 Antikörper) in BALF.

  2. RANK/RANKL signaling is involved in the androgen deprivation therapy-induced acceleration of bone metastasis in castration-insensitive prostate cancer and is inhibited by osteoprotegerin (zeige TNFRSF11B Antikörper) to prevent bone metastasis.

  3. This study suggested that RANKL could be a marker to differentiate between pagetoid squamous cell carcinoma in situ and extramammary Paget disease .

  4. TNF-alpha-converting enzyme (zeige ADAM17 Antikörper) -mediated cleavage of soluble RANKL from activated lymphocytes, especially B cells, can promote osteoclastogenesis in periodontitis.

  5. RANKL is required for progesterone-mediated cell proliferation in BRCA1mut/+ breast tissue.

  6. MAOA (zeige MAOA Antikörper) provides tumor cell growth advantages in the bone microenvironment by stimulating interleukin-6 (IL6 (zeige IL6 Antikörper)) release from osteoblasts, and triggers skeletal colonization by activating osteoclastogenesis through osteoblast production of RANKL and IL6 (zeige IL6 Antikörper).

  7. In this review, we will provide a summary of the biological functions of RANK signaling pathway (receptor activator of nuclear factor kappaB ligand RANKL and its receptor RANK ) and downstream pathways in bone remodeling, immunity and epithelial homeostasis, with a particular emphasis on cancer

  8. The results showed that AG490 inhibited (p)-JAK2 (zeige JAK2 Antikörper) and RANKL expression.

  9. Review: OPG (zeige TNFRSF11B Antikörper), RANKL and TRAIL are involved in vascular calcification.

  10. Our results suggest that the polymorphism of the RANKL, RANK, and OPG (zeige TNFRSF11B Antikörper) genes does not make a significant genetic contribution to heel ultrasound measurements in a population of young Caucasian adults. Further studies replicating the results in independent populations are needed to support these initial findings.

Mouse (Murine) Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) Interaktionspartner

  1. Data suggest that mutations at position I248 in DE-loop of murine RANKL have effects on interaction of RANKL with RANK and on subsequent activation of osteoclastogenesis by this hetero-multimer. (RANKL = osteoclast differentiation factor; RANK = tumor necrosis factor (zeige TNF Antikörper) receptor superfamily, member 11a protein)

  2. sRANKL increased macrophage glucose uptake at normal glucose concentrations, which was impaired by hyperglycemia pretreatment through the inhibition of Glut1 (zeige SLC2A1 Antikörper) membrane translocation and the insulin receptor (zeige INSR Antikörper) and IRS-1 (zeige IRS1 Antikörper) gene transcription.

  3. Our findings show that anti-RANKL antibody administration during pregnancy results in not only an undesirable increase in bone mass, but also has harmful effects on newborn survival.

  4. RANKL represses the transcription of the E3 ubiquitin ligase (zeige MUL1 Antikörper) RNF146 (zeige RNF146 Antikörper) through an NF-kappaB (zeige NFKB1 Antikörper)-related inhibitory element in the RNF146 (zeige RNF146 Antikörper) promoter.

  5. This study showed that RANKL favors osteoclastogenesis via attenuation of Nrf2 (zeige NFE2L2 Antikörper)-mediated antioxidant enzyme expression by competing with Bach1 (zeige BACH1 Antikörper) nuclear accumulation.

  6. Membrane-bound RANKL induces M cell differentiation and CCL20 (zeige CCL20 Antikörper) expression in the follicle associated epithelium of gut (zeige GUSB Antikörper)-associated lymphoid tissues.

  7. The data show that S. aureus enhances bone resorption and periosteal osteoclast formation by increasing osteoblast RANKL production through TLR2 (zeige TLR2 Antikörper).

  8. Data (including data from studies using knockout mice) suggest that RANKL enhances TNF (zeige TNF Antikörper)-induced osteoclast formation from precursor spleen cells and enhances bone resorption independently of Traf6 (zeige TRAF6 Antikörper) by degrading Traf3 (zeige TRAF3 Antikörper), a known inhibitor of osteoclastogenesis. (RANKL = osteoclast differentiation factor; TNF (zeige TNF Antikörper) = tumor necrosis factor (zeige TNF Antikörper); Traf (zeige TRAF1 Antikörper) = TNF (zeige TNF Antikörper) receptor-associated factor)

  9. Results suggest that MAPK (zeige MAPK1 Antikörper) signaling pathway is necessary for receptor activator of nuclear factor kappa-B ligand (RANKL) expression in bone marrow stromal cell.

  10. endocortical resorption is driven by reduced osteoprotegerin (zeige TNFRSF11B Antikörper) rather than elevated RANKL expression

TNFSF11 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced transcript variants have been found.

Alternative names and synonyms associated with TNFSF11

  • tumor necrosis factor (ligand) superfamily, member 11 (TNFSF11) Antikörper
  • basic transcription factor 3 pseudogene 11 (BTF3P11) Antikörper
  • tumor necrosis factor (ligand) superfamily, member 11 (Tnfsf11) Antikörper
  • tumor necrosis factor receptor superfamily, member 11b (Tnfrsf11b) Antikörper
  • tumor necrosis factor receptor superfamily, member 11b (TNFRSF11B) Antikörper
  • BTF3L1 Antikörper
  • CD254 Antikörper
  • hRANKL2 Antikörper
  • HUMBTFB Antikörper
  • Ly109l Antikörper
  • OCIF Antikörper
  • ODF Antikörper
  • Opg Antikörper
  • OPGL Antikörper
  • OPTB2 Antikörper
  • RANKL Antikörper
  • sOdf Antikörper
  • TNFRSF11B Antikörper
  • TNFSF11 Antikörper
  • Trance Antikörper

Bezeichner auf Proteinebene für TNFSF11

tumor necrosis factor (ligand) superfamily, member 11 , tumor necrosis factor ligand superfamily member 11 , Receptor activator of nuclear factor kappa-B ligand , TNF-related activation-induced cytokine , osteoclast differentiation factor , osteoprotegerin ligand , receptor activator of nuclear factor kappa B ligand , receptor activator of nuclear factor kappa-B ligand , OPG ligand , receptor activator of NF-kappaB ligand , tumor necrosis factor-related activation-induced cytokine , ODF , OPGL , TRANCE , Osteoprotegerin , tumor necrosis factor receptor superfamily member 11B , tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)

467353 Pan troglodytes
513836 Bos taurus
609418 Canis lupus familiaris
699955 Macaca mulatta
100599838 Nomascus leucogenys
690 Homo sapiens
8600 Homo sapiens
21943 Mus musculus
117516 Rattus norvegicus
25341 Rattus norvegicus
378803 Gallus gallus
Ausgewählte Anbieter für anti-TNFSF11 (TNFSF11) Antikörper
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