anti-TNFRSF11A (TNFRSF11A) Antikörper

anti-Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator Antikörper (TNFRSF11A)
Auf finden Sie aktuell 134 Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) Antikörper von 21 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TNFRSF11A Kits (34) und TNFRSF11A Proteine (23) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 200 TNFRSF11A Produkte verfügbar.
Alle Antikörper anzeigen Gen GeneID UniProt
TNFRSF11A 498206  
TNFRSF11A 21934 O35305
TNFRSF11A 8792 Q9Y6Q6

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Meistgesuchte Reaktivitäten zu anti-TNFRSF11A (TNFRSF11A) Antikörper

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anti-Rat (Rattus) TNFRSF11A Antikörper:

anti-Mouse (Murine) TNFRSF11A Antikörper:

anti-Human TNFRSF11A Antikörper:

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Am meisten referenzierte anti-TNFRSF11A Antikörper

  1. Human Monoclonal TNFRSF11A Primary Antibody für CyTOF, FACS - ABIN252472 : Fiumara, Snell, Li, Mukhopadhyay, Younes, Gillenwater, Cabanillas, Aggarwal, Younes: Functional expression of receptor activator of nuclear factor kappaB in Hodgkin disease cell lines. in Blood 2001 (PubMed)
    Zeige alle 15 Referenzen für 252472

  2. Human Monoclonal TNFRSF11A Primary Antibody für FACS, IHC (p) - ABIN252036 : Lee, Kim, Jun, Yoo, Woo, Choi, Lee, Song, Sohn, Park-Min, Ivashkiv, Ji: Direct inhibition of human RANK+ osteoclast precursors identifies a homeostatic function of IL-1beta. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Zeige alle 10 Referenzen für 252036

  3. Mouse (Murine) Monoclonal TNFRSF11A Primary Antibody für FACS - ABIN2663245 : Anderson, Maraskovsky, Billingsley, Dougall, Tometsko, Roux, Teepe, DuBose, Cosman, Galibert: A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. in Nature 1997 (PubMed)
    Zeige alle 7 Referenzen für 2663245

  4. Human Monoclonal TNFRSF11A Primary Antibody für ELISA (Capture), FACS - ABIN4900544 : Vernal, Dutzan, Hernández, Chandía, Puente, León, García, Del Valle, Silva, Gamonal: High expression levels of receptor activator of nuclear factor-kappa B ligand associated with human chronic periodontitis are mainly secreted by CD4+ T lymphocytes. in Journal of periodontology 2006 (PubMed)
    Zeige alle 5 Referenzen für 4900544

  5. Mouse (Murine) Monoclonal TNFRSF11A Primary Antibody für FACS - ABIN2661015 : Ha, Choi, Lee, Kwon, Song, Kim: CXC chemokine ligand 2 induced by receptor activator of NF-kappa B ligand enhances osteoclastogenesis. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Zeige alle 4 Referenzen für 2661015

  6. Human Monoclonal TNFRSF11A Primary Antibody für FACS - ABIN4897927 : Riegel, Maurer, Prior, Stegmaier, Heppert, Wagner, Hänsch: Human polymorphonuclear neutrophils express RANK and are activated by its ligand, RANKL. in European journal of immunology 2012 (PubMed)

Weitere Antikörper gegen TNFRSF11A Interaktionspartner

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) Interaktionspartner

  1. Data suggest that mutations at position I248 in DE-loop of murine RANKL (zeige TNFSF11 Antikörper) have effects on interaction of RANKL (zeige TNFSF11 Antikörper) with RANK and on subsequent activation of osteoclastogenesis by this hetero-multimer. (RANKL (zeige TNFSF11 Antikörper) = osteoclast differentiation factor (zeige TNFSF11 Antikörper); RANK = tumor necrosis factor (zeige TNF Antikörper) receptor superfamily, member 11a protein)

  2. The persistence of bone erosion and synovial osteoclasts in Rank-deficient mice, and the ability of TNF (zeige TNF Antikörper)/IL-6 (zeige IL6 Antikörper) to induce osteoclastogenesis, suggest that more than one cytokine pathway exists to generate these bone-resorbing cells in inflamed joints.

  3. Muscle RANK deletion had no significant effects on the sham or denervated slow-twitch soleus muscles. These data identify a novel role for RANK as a key regulator of Ca(2 (zeige CA2 Antikörper)+)storage and SERCA (zeige ATP2A3 Antikörper) activity, ultimately affecting denervated skeletal muscle function.

  4. present study shows that ginsenoside Rg3 protects against LPS (zeige TLR4 Antikörper)-induced acute lung injury through inactivating the NF-kappaB (zeige NFKB1 Antikörper) signaling

  5. In palmatine-treated mice, RANKL (zeige TNFSF11 Antikörper) and OPG (zeige TNFSF11 Antikörper) expression decreased. In the culture supernatant of MC3T3-E1 cells, RANKL (zeige TNFSF11 Antikörper) and OPG (zeige TNFSF11 Antikörper) levels were significantly reduced by palmatine addition.

  6. Results show that moderate increases in affinity for RANK lead to a substantial augmentation of osteoclast formation, signaling, and bone resorption suggesting a biphasic relationship between RANKL (zeige TNFSF11 Antikörper)/RANK affinity and osteoclastogenic capacity.

  7. Dissection of the mechanism by which this occurs indicates that mCripto-1 activates receptor activator NF-kappaB (zeige NFKB1 Antikörper)/receptor activator NF-kappaB (zeige NFKB1 Antikörper) ligand, and NF-kappaB (zeige NFKB1 Antikörper) signaling pathways.

  8. We also show that R-spondin1 (zeige RSPO1 Antikörper) is depleted in RANK-null progenitors, and that its exogenous administration rescues key aspects of RANK deficiency by reinstating a WNT (zeige WNT2 Antikörper) response and mammary cell expansion

  9. findings have uncovered a tumorigenic role for RANKL (zeige TNFSF11 Antikörper)/RANK in the salivary gland and suggest that targeting this pathway may represent a novel therapeutic intervention approach in the prevention and/or treatment of this understudied head and neck cancer

  10. results indicate that the RANK IVVY motif cooperates with the TRAF (zeige TRAF1 Antikörper)-binding motifs to promote osteoclastogenesis, which provides novel insights into the molecular mechanism of RANK signaling in osteoclastogenesis.

Human Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) Interaktionspartner

  1. RANK/RANKL (zeige TNFSF11 Antikörper) signaling is involved in the androgen deprivation therapy-induced acceleration of bone metastasis in castration-insensitive prostate cancer and is inhibited by osteoprotegerin (zeige TNFRSF11B Antikörper) to prevent bone metastasis.

  2. In histologically normal tissue of BRCA1-mutation carriers and showed that RANK(+) cells are highly proliferative, have grossly aberrant DNA repair and bear a molecular signature similar to that of basal-like breast cancer.

  3. In this review, we will provide a summary of the biological functions of RANK signaling pathway (receptor activator of nuclear factor kappaB ligand RANKL (zeige TNFSF11 Antikörper) and its receptor RANK ) and downstream pathways in bone remodeling, immunity and epithelial homeostasis, with a particular emphasis on cancer

  4. Our results suggest that the polymorphism of the RANKL (zeige TNFSF11 Antikörper), RANK, and OPG (zeige TNFRSF11B Antikörper) genes does not make a significant genetic contribution to heel ultrasound measurements in a population of young Caucasian adults. Further studies replicating the results in independent populations are needed to support these initial findings.

  5. Vav3 (zeige VAV3 Antikörper) is a novel TRAF6 (zeige TRAF6 Antikörper) interaction partner that functions in the activation of cooperative signaling between T6BSs and the IVVY motif in the RANK signaling complex.

  6. OPG (zeige TNFRSF11B Antikörper) rs2073618, RANK rs75404003, and RANKL (zeige TNFSF11 Antikörper) rs9594782 single nucleotide poymorphisms may predispose LVH in thalassemia patients.

  7. Twenty-one single-nucleotide polymorphisms (SNPs) of TNFSF11, TNFRSF11A, and TNFRSF11B were genotyped. This study suggests that TNFRSF11B but not TNFSF11 and TNFRSF11A genetic polymorphisms are associated with Type 2 Diabetes Mellitus in Southern Han Chinese women.

  8. the OPG/RANKL (zeige TNFSF11 Antikörper)/RANK system might be directly influenced by genetic variants of NOTCH1 (zeige NOTCH1 Antikörper) in aortic valve calcification.

  9. Postmenopausal women with Rheumatoid Arthritis, carrying either the RANKL (zeige TNFSF11 Antikörper)-290T allele or possessing the RANK 575CC genotype were more likely to develop osteoporosis.

  10. The RANK/RANKL (zeige TNFSF11 Antikörper) system induces chemoresistance.

TNFRSF11A Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.

Alternative names and synonyms associated with TNFRSF11A

  • tumor necrosis factor receptor superfamily, member 11a, NFKB activator (Tnfrsf11a) Antikörper
  • tumor necrosis factor receptor superfamily, member 11a, NFKB activator (TNFRSF11A) Antikörper
  • tumor necrosis factor receptor superfamily, member 11a (Tnfrsf11a) Antikörper
  • CD265 Antikörper
  • FEO Antikörper
  • LOH18CR1 Antikörper
  • Ly109 Antikörper
  • mRANK Antikörper
  • ODFR Antikörper
  • OFE Antikörper
  • OPTB7 Antikörper
  • OSTS Antikörper
  • PDB2 Antikörper
  • Rank Antikörper
  • RGD1563614 Antikörper
  • TNFRSF11A Antikörper
  • TRANCE-R Antikörper
  • TRANCER Antikörper

Bezeichner auf Proteinebene für TNFRSF11A

tumor necrosis factor receptor superfamily member 11A , tumor necrosis factor receptor superfamily, member 11a, NFKB activator , receptor activator of nuclear factor-kappa B , tumor necrosis factor receptor superfamily member 11A-like , osteoclast differentiation factor receptor , receptor activator of NF-KB , receptor activator of NF-kappaB , loss of heterozygosity, 18, chromosomal region 1

498206 Rattus norvegicus
468560 Pan troglodytes
483957 Canis lupus familiaris
530884 Bos taurus
769909 Gallus gallus
100358260 Oryctolagus cuniculus
100433235 Pongo abelii
21934 Mus musculus
8792 Homo sapiens
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