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anti-SQSTM1 (SQSTM1) Antikörper

Bezeichnung:
anti-Sequestosome 1 Antikörper (SQSTM1)
Auf www.antikoerper-online.de finden Sie aktuell 301 Sequestosome 1 (SQSTM1) Antikörper von 21 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SQSTM1 Proteine (14) und SQSTM1 Kits (8) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 337 SQSTM1 Produkte verfügbar.
Synonyme:
A170, MGC79491, OSF-6, Osi, OSIL, p60, p62, p62B, PDB3, sb:cb621, sqstm1, STAP, zgc:85784, ZIP, ZIP3

Meistgesuchte Reaktivitäten zu anti-SQSTM1 (SQSTM1) Antikörper

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anti-Human SQSTM1 Antikörper:

anti-Mouse (Murine) SQSTM1 Antikörper:

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Am meisten referenzierte anti-SQSTM1 Antikörper

  1. Human Polyclonal SQSTM1 Primary Antibody für IF, IHC (p) - ABIN388979 : Seibenhener, Babu, Geetha, Wong, Krishna, Wooten: Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation. in Molecular and cellular biology 2004 (PubMed)
    Zeige alle 22 Referenzen für ABIN388979

  2. Human Polyclonal SQSTM1 Primary Antibody für EIA, IF - ABIN4620406 : Chu, Wang, Wu, Lei: Invasion and multiplication of Helicobacter pylori in gastric epithelial cells and implications for antibiotic resistance. in Infection and immunity 2010 (PubMed)
    Zeige alle 12 Referenzen für ABIN4620406

  3. Human Polyclonal SQSTM1 Primary Antibody für EIA, IHC (p) - ABIN497992 : Hocking, Lucas, Daroszewska, Mangion, Olavesen, Cundy, Nicholson, Ward, Bennett, Wuyts, Van Hul, Ralston: Domain-specific mutations in sequestosome 1 (SQSTM1) cause familial and sporadic Paget's disease. in Human molecular genetics 2002 (PubMed)
    Zeige alle 5 Referenzen für ABIN497992

  4. Human Polyclonal SQSTM1 Primary Antibody für WB - ABIN1881829 : Visconti, Langston, Alonso, Goodman, Selby, Fraser, Ralston: Mutations of SQSTM1 are associated with severity and clinical outcome in paget disease of bone. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010 (PubMed)
    Zeige alle 5 Referenzen für ABIN1881829

  5. Human Polyclonal SQSTM1 Primary Antibody für DB - ABIN1881831 : Ding, Ni, Li, Liao, Chen, Stolz, Dorn, Yin: Nix is critical to two distinct phases of mitophagy, reactive oxygen species-mediated autophagy induction and Parkin-ubiquitin-p62-mediated mitochondrial priming. in The Journal of biological chemistry 2010 (PubMed)
    Zeige alle 5 Referenzen für ABIN1881831

  6. Human Monoclonal SQSTM1 Primary Antibody für IF, ELISA - ABIN393579 : Xia, Liu, Xie, Zhu, Guerra, Shen, Yeddula, Fischer, Low, Zhou, Zhang, Oldfield, Verma: A combination therapy for KRAS-driven lung adenocarcinomas using lipophilic bisphosphonates and rapamycin. in Science translational medicine 2014 (PubMed)

  7. Human Polyclonal SQSTM1 Primary Antibody für ICC, IF - ABIN449244 : Eason, Bell, Marshall, Rodgers, Pineda, Steiger, Al-Riyami, Harnett, Harnett: The helminth product, ES-62 modulates dendritic cell responses by inducing the selective autophagolysosomal degradation of TLR-transducers, as exemplified by PKCδ. in Scientific reports 2016 (PubMed)

  8. Human Polyclonal SQSTM1 Primary Antibody für ICC, IF - ABIN449246 : Zhang, Gui, Huang, Deng, Fang, Ke, He, Li, Fang: Neuroprotective Effects of β-Asarone Against 6-Hydroxy Dopamine-Induced Parkinsonism via JNK/Bcl-2/Beclin-1 Pathway. in Molecular neurobiology 2016 (PubMed)

Weitere Antikörper gegen SQSTM1 Interaktionspartner

Human Sequestosome 1 (SQSTM1) Interaktionspartner

  1. These results demonstrated that p62-dependent mitophagy has an immunosuppressive role to innate immune response and might serve as a potential immunomodulatory target for inflammation-associated diseases.

  2. siRNA-mediated knockdown of p62 clearly increased the efficiency of transfection of murine embryonic stem (mES) cells and human HeLa cells. These data indicate that p62 acts as a key regulator of gene delivery.

  3. These studies suggest that p62 is involved in the genesis of nuclear factor kappaB-induced proinflammatory and prolabor mediators.

  4. In this review, we discuss p62-mediated signaling pathways and their roles in liver pathophysiology, especially nonalcoholic steatohepatitis and hepatocellular carcinoma

  5. findings expand the SQSTM1-associated phenotypic spectrum and lend further support to the concept of disturbed selective autophagy pathways in neurodegenerative diseases

  6. Aldo was revealed to induce autophagy, as indicated by the increased conversion from microtubuleassociated protein 1A/1Blight chain 3 (LC3)I to LC3II, the increased expression levels of autophagyrelated gene 7 (Atg7) and the increased degradation of p62, which was accompanied by MC proliferation

  7. Results demonstrate that p62 (zeige GTF2H1 Antikörper) facilitates activation of NRF2 (zeige GABPA Antikörper) and mTORC1 and is essential for hepatocellular carcinomas (HCC (zeige FAM126A Antikörper)) initiation. High levels of p62 accumulation in non-tumor liver tissue in early-stage HCC patients.

  8. Results show that Nrf2 (zeige GABPA Antikörper) prevents TM-induced apoptotic cell death and that TM promotes p62 (zeige GTF2H1 Antikörper)-dependent autophagic Keap1 (zeige KEAP1 Antikörper) degradation, leading to Nrf2 (zeige GABPA Antikörper) activation. In addition, we identified that p62 (zeige GTF2H1 Antikörper) is essential to protect cells against TM-mediated oxidative damage through Nrf2 (zeige GABPA Antikörper) activation.

  9. Spinal stenosis emerges as a prominent phenotype in SQSTM1 P392L-positive men with aging

  10. p62 is a crucial positive regulator of HIF1alpha, which is a facilitating factor in p62-enhanced tumorigenesis.

Mouse (Murine) Sequestosome 1 (SQSTM1) Interaktionspartner

  1. two ALS-linked factors, SQSTM1 and ALS2 (zeige ALS2 Antikörper), have distinct but additive protective roles against mutant SOD1 (zeige SOD1 Antikörper)-mediated toxicity by modulating neuronal proteostasis possibly through the autophagy-endolysosomal system.

  2. These results demonstrated that p62-dependent mitophagy has an immunosuppressive role to innate immune response and might serve as a potential immunomodulatory target for inflammation-associated diseases.

  3. results indicate that autophagy is important for the removal of excess Endoplasmic Reticulum and hepatic CYP enzymes in mouse livers, a process associated with the autophagy receptor protein p62.

  4. p62 (zeige GTF2H1 Antikörper) reduces UVB-induced apoptosis by modulating intrinsic apoptotic signaling through Src (zeige SRC Antikörper) phosphorylation.

  5. Our results indicate that JEV replication is impaired in p62-deficient MEFs, suggesting that p62 positively regulates JEV replication in host cells.

  6. Results demonstrate that p62 (zeige GTF2H1 Antikörper) facilitates activation of NRF2 (zeige NFE2L2 Antikörper) and mTORC1 and is essential for hepatocellular carcinomas (HCC (zeige FAM126A Antikörper)) initiation.

  7. p62 may be a crucial mediator for the mitochondrial apoptosis pathway in Monosodium Urate crystal-induced inflammation, which is linked to the acute inflammatory response during the early phase of gout.

  8. Results show that Nrf2 (zeige NFE2L2 Antikörper) prevents TM-induced apoptotic cell death and that TM promotes p62 (zeige GTF2H1 Antikörper)-dependent autophagic Keap1 (zeige KEAP1 Antikörper) degradation, leading to Nrf2 (zeige NFE2L2 Antikörper) activation. In addition, we identified that p62 (zeige GTF2H1 Antikörper) is essential to protect cells against TM-mediated oxidative damage through Nrf2 (zeige NFE2L2 Antikörper) activation.

  9. the molecular basis for the escape of TBC1D25 (zeige TBC1D25 Antikörper) from autophagic degradation by performing a chimeric analysis between TBC1D25 (zeige TBC1D25 Antikörper) and SQSTM1/p62, was investigated.

  10. p62 (zeige GTF2H1 Antikörper) are subjected to parkin (zeige PARK2 Antikörper) mediated proteasomal degradation

Zebrafish Sequestosome 1 (SQSTM1) Interaktionspartner

  1. Loss-of-function of SQSTM1 may cause phenotypic features characterized by locomotor deficits and motor neuron axonal defects that are associated with a misregulation of autophagic processes.

SQSTM1 Antigen-Profil

Beschreibung des Gens

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Alternative names and synonyms associated with SQSTM1

  • sequestosome 1 (SQSTM1) Antikörper
  • sequestosome 1 (LOC100342157) Antikörper
  • sqstm1 protein (sqstm1) Antikörper
  • sequestosome 1 (Sqstm1) Antikörper
  • sequestosome 1 (sqstm1) Antikörper
  • A170 Antikörper
  • MGC79491 Antikörper
  • OSF-6 Antikörper
  • Osi Antikörper
  • OSIL Antikörper
  • p60 Antikörper
  • p62 Antikörper
  • p62B Antikörper
  • PDB3 Antikörper
  • sb:cb621 Antikörper
  • sqstm1 Antikörper
  • STAP Antikörper
  • zgc:85784 Antikörper
  • ZIP Antikörper
  • ZIP3 Antikörper

Bezeichner auf Proteinebene für SQSTM1

sequestosome 1 , sequestosome-1 , sequestosome-1-like , sqstm1 protein , EBI3-associated protein of 60 kDa , EBI3-associated protein p60 , EBIAP , oxidative stress induced like , phosphotyrosine independent ligand for the Lck SH2 domain p62 , phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa , ubiquitin-binding protein p62 , STONE14 , oxidative stress induced , PKC-zeta-interacting protein , protein kinase C-zeta-interacting protein

GENE ID SPEZIES
462333 Pan troglodytes
705481 Macaca mulatta
770805 Gallus gallus
100135450 Ovis aries
100342157 Oryctolagus cuniculus
100385650 Callithrix jacchus
493277 Xenopus (Silurana) tropicalis
100067231 Equus caballus
8878 Homo sapiens
18412 Mus musculus
113894 Rattus norvegicus
406452 Danio rerio
379610 Xenopus laevis
338045 Bos taurus
481459 Canis lupus familiaris
100172461 Pongo abelii
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