anti-SQSTM1 (SQSTM1) Antikörper

Auf www.antikoerper-online.de finden Sie aktuell 307 Sequestosome 1 (SQSTM1) Antikörper von 22 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SQSTM1 Proteine (14) und SQSTM1 Kits (8) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 344 SQSTM1 Produkte verfügbar.
Synonyme:
A170, MGC79491, OSF-6, Osi, OSIL, p60, p62, p62B, PDB3, sb:cb621, sqstm1, STAP, zgc:85784, ZIP, ZIP3
Alle Antikörper anzeigen Gen GeneID UniProt
SQSTM1 8878 Q13501
SQSTM1 18412 Q64337
SQSTM1 113894 O08623

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Weitere Antikörper gegen SQSTM1 Interaktionspartner

Human Sequestosome 1 (SQSTM1) Interaktionspartner

  1. we provide evidence that p62 (zeige GTF2H1 Antikörper) is implicated in the activation of NF-kappaB (zeige NFKB1 Antikörper) signaling that is partly dependent on RIP1 (zeige UQCRFS1 Antikörper)

  2. In this study, we first observed that p62-positive intranuclear aggregates also appeared in controls and were not specific for the Neuronal Intranuclear Hyaline Inclusion Disease cases.

  3. Data suggest that phosphorylation of SQSTM1 by AMP-activated protein kinase (AMPK (zeige PRKAA2 Antikörper)) and translocation of SQSTM1 to mitochondria drives autophagic cell death in adult hippocampal neural stem cells; activation of AMPK (zeige PRKAA1 Antikörper) promotes autophagic cell death; inhibition of AMPK (zeige PRKAA1 Antikörper) (by enzyme inhibitor or RNA interference) suppresses autophagic cell death. (SQSTM1 = sequestosome 1)

  4. Authors found that p62/SQSTM1, a protein upregulated in liver parenchymal cells but downregulated in HCC (zeige FAM126A Antikörper)-associated HSCs, negatively controls hepatic stellate cells activation.

  5. necessary for retinal pigmented epithelial cytoprotection under oxidative stress; NFkappaB p65 activity may be critical upstream initiator of p62 expression in retinal pigmented epithelial cells under oxidative stress

  6. p62/SQSTM1, which accumulates in autophagy-defective cells, directly binds to and inhibits nuclear RNF168 (zeige RNF168 Antikörper), an E3 ligase essential for histone H2A ubiquitination and DNA damage responses. As a result, DNA repair proteins such as BRCA1, RAP80 (zeige UIMC1 Antikörper), and Rad51 (zeige RAD51 Antikörper) cannot be recruited to the sites of DNA double-strand breaks (DSBs), which impairs DSB repair.

  7. propose that the interplay between LRRK2 (zeige LRRK2 Antikörper) and p62 (zeige GTF2H1 Antikörper) may contribute to the pathophysiological function and homeostasis of LRRK2 (zeige LRRK2 Antikörper) protein

  8. Frontotemporal dementia -linked mutations in gene p62/SQSTM1 encoding autophagy adaptor proteins , indicate that impaired autophagy might cause Frontotemporal dementia.

  9. These data suggest that SQSTM1 mutations are not a common cause of normal tension glaucoma.

  10. These results demonstrated that p62-dependent mitophagy has an immunosuppressive role to innate immune response and might serve as a potential immunomodulatory target for inflammation-associated diseases.

Mouse (Murine) Sequestosome 1 (SQSTM1) Interaktionspartner

  1. Our findings show how p62 helps maintain intracellular pools of glutathione needed to limit mitochondrial dysfunction in tumor cells with elevated mTORC1

  2. TRIM14 inhibits cGAS degradation mediated by selective autophagy receptor p62 to promote innate immune responses.

  3. Authors found that p62/SQSTM1, a protein upregulated in liver parenchymal cells but downregulated in HCC (zeige FAM126A Antikörper)-associated HSCs, negatively controls hepatic stellate cells activation.

  4. SQSTM1 or damaged proteins may be transported from the nose to the brain. These findings strongly implicate widespread protein damage in the etiology of flavorings-related lung disease.

  5. Promoting amino acid sensitivity of the mTOR pathway is dependent on p62 accumulation by inhibition of autophagy and this process plays an important role in the hepatic differentiation of stem/progenitor cells.

  6. role of p62 (zeige GTF2H1 Antikörper) in MDB (zeige ABR Antikörper) maturation and stability

  7. two ALS-linked factors, SQSTM1 and ALS2 (zeige ALS2 Antikörper), have distinct but additive protective roles against mutant SOD1 (zeige SOD1 Antikörper)-mediated toxicity by modulating neuronal proteostasis possibly through the autophagy-endolysosomal system.

  8. These results demonstrated that p62-dependent mitophagy has an immunosuppressive role to innate immune response and might serve as a potential immunomodulatory target for inflammation-associated diseases.

  9. results indicate that autophagy is important for the removal of excess Endoplasmic Reticulum and hepatic CYP enzymes in mouse livers, a process associated with the autophagy receptor protein p62.

  10. p62 (zeige GTF2H1 Antikörper) reduces UVB-induced apoptosis by modulating intrinsic apoptotic signaling through Src (zeige SRC Antikörper) phosphorylation.

Zebrafish Sequestosome 1 (SQSTM1) Interaktionspartner

  1. Loss-of-function of SQSTM1 may cause phenotypic features characterized by locomotor deficits and motor neuron axonal defects that are associated with a misregulation of autophagic processes.

SQSTM1 Antigen-Profil

Beschreibung des Gens

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Alternative names and synonyms associated with SQSTM1

  • sequestosome 1 (SQSTM1) Antikörper
  • sequestosome 1 (LOC100342157) Antikörper
  • sqstm1 protein (sqstm1) Antikörper
  • sequestosome 1 (Sqstm1) Antikörper
  • sequestosome 1 (sqstm1) Antikörper
  • A170 Antikörper
  • MGC79491 Antikörper
  • OSF-6 Antikörper
  • Osi Antikörper
  • OSIL Antikörper
  • p60 Antikörper
  • p62 Antikörper
  • p62B Antikörper
  • PDB3 Antikörper
  • sb:cb621 Antikörper
  • sqstm1 Antikörper
  • STAP Antikörper
  • zgc:85784 Antikörper
  • ZIP Antikörper
  • ZIP3 Antikörper

Bezeichner auf Proteinebene für SQSTM1

sequestosome 1 , sequestosome-1 , sequestosome-1-like , sqstm1 protein , EBI3-associated protein of 60 kDa , EBI3-associated protein p60 , EBIAP , oxidative stress induced like , phosphotyrosine independent ligand for the Lck SH2 domain p62 , phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa , ubiquitin-binding protein p62 , STONE14 , oxidative stress induced , PKC-zeta-interacting protein , protein kinase C-zeta-interacting protein

GENE ID SPEZIES
462333 Pan troglodytes
705481 Macaca mulatta
770805 Gallus gallus
100135450 Ovis aries
100342157 Oryctolagus cuniculus
100385650 Callithrix jacchus
493277 Xenopus (Silurana) tropicalis
100067231 Equus caballus
8878 Homo sapiens
18412 Mus musculus
113894 Rattus norvegicus
406452 Danio rerio
379610 Xenopus laevis
338045 Bos taurus
481459 Canis lupus familiaris
100172461 Pongo abelii
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