anti-Ratte (Rattus) RANK Antikörper für Western Blotting

Recommended RANK Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
RANK (CD265) Antikörper
  • Ly109
  • ODFR
  • OFE
  • Rank
  • TRANCE-R
  • mRANK
  • CD265
  • FEO
  • LOH18CR1
  • OPTB7
  • OSTS
  • PDB2
  • RANK
  • TRANCER
  • RGD1563614
  • tumor necrosis factor receptor superfamily, member 11a
  • tumor necrosis factor receptor superfamily, member 11a, NFKB activator
  • Tnfrsf11a
  • TNFRSF11A
Reaktivität
Human, Maus, Ratte (Rattus)
69
37
16
Wirt
Kaninchen
59
15
9
1
Klonalität
Polyklonal
Konjugat
Dieser RANK Antikörper ist unkonjugiert
7
6
4
3
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
56
27
24
19
14
12
12
2
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN1714635
304,36 €
Zzgl. Versandkosten 20,00 € und MWSt
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Ähnliche anti-RANK Antikörper

Applikation / Reaktivität Ratte (Rattus) Maus Human
ELISA 2 Antikörper 9 Antikörper 16 Antikörper
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antikörper 13 Antikörper 13 Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 4 Antikörper 8 Antikörper 20 Antikörper
Western Blotting (WB) 5 Antikörper 14 Antikörper
Flow Cytometry (FACS) 14 Antikörper 18 Antikörper
Functional Studies (Func) 2 Antikörper
Immunohistochemistry (IHC) 2 Antikörper 10 Antikörper
Immunoprecipitation (IP) 5 Antikörper 10 Antikörper
Neutralization (Neut) 1 Antikörper

General

Antigen RANK (CD265) Antikörper
Reaktivität Human, Maus, Ratte (Rattus)
(69), (37), (16)
Wirt Kaninchen
(59), (15), (9), (1)
Klonalität
Polyklonal
Konjugat Dieser RANK Antikörper ist unkonjugiert
(7), (6), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(56), (27), (24), (19), (14), (12), (12), (2), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-RANK Antikörper

Target Details RANK Anwendungsinformationen Handhabung Bilder
Reinigung Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human RANK
Isotyp IgG

Target Details RANK

Produktdetails anti-RANK Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Rank (CD265 Antibody Abstract)
Hintergrund

CD265 is a member of the tumor necrosis factor receptor (TNFR) family. Human and murine CD265 share 81 % amino acid identity in their extracellular domains. CD265 is widely expressed, with highest levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland. CD265 is also expressed in dendritic cells. RANK and RANK ligand (RANKL) are important regulators of interactions between T cells and dendritic cells. RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis. Multiple tumor necrosis factor receptor-associated factors (TRAFs) are involved in the signaling of CD265. TRANCE (TNF-related activation-induced cytokines, also known as RANK ligand, osteoprotegerin ligand and osteoclast differentiation factor) is the ligand for CD265. The biological functions mediated by RANK include activation of NFkappaB and cjun N-terminal kinase, enhancement of T cell growth and dendritic cell function, induction of osteoclastogenesis and lymph node organogenesis. The soluble form of CD265 is able to block TRANCE induced biological activity. The binding of anti-CD265 to cell surface CD265 triggers signal transduction and induces CD265 mediated bioactivity.

Subcellular location: Extracellular

Synonyms: TNFRSF11A, CD 265, CD265, CD265 antigen, Activator of NFKB, EOF, FEO, mRANK, NFKB activator, ODFR, OFE, Osteoclast dferentiation factor receptor, PDB 2, Receptor activator of NF KB, receptor activator of nuclear factor kappa B, TNFRSF 11A, TNFSF11, TRANCE R, RANK receptor, TNR11_HUMAN.

Forschungsgebiet Cardiovascular, Atherosclerosis, Extracellular Matrix, Innate Immunity, Cytokines
Pathways NF-kappaB Signalweg

Anwendungsinformationen

Produktdetails anti-RANK Antikörper Target Details RANK Handhabung Bilder zurück nach oben
Applikationshinweise WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-RANK Antikörper Target Details RANK Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months

Bilder

Produktdetails anti-RANK Antikörper Target Details RANK Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-RANK Antikörper (CD265) (ABIN1714635) Paraformaldehyde-fixed, paraffin embedded mouse brain tissue, Antigen retrieval by bo...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-RANK Antikörper (CD265) (ABIN1714635) Paraformaldehyde-fixed, paraffin embedded rat skeletal muscle tissue, Antigen retriev...