anti-Meerschweinchen PKC zeta Antikörper für Western Blotting

Recommended PKC zeta Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Protein Kinase C, zeta (PRKCZ) Antikörper
  • TPKC
  • PKCzeta
  • prkcz-A
  • pkc-zeta
  • PRKCZ
  • pkc2
  • PKC-ZETA
  • PKC2
  • AI098070
  • C80388
  • Pkcz
  • R74924
  • aPKCzeta
  • zetaPKC
  • 14-3-3-zetaisoform
  • r14-3-3
  • pkcz
  • si:ch211-150o23.4
  • protein kinase C zeta L homeolog
  • protein kinase C zeta
  • protein kinase C, zeta
  • prkcz.L
  • PRKCZ
  • prkcz
  • Prkcz
Epitop
N-Term
41
31
17
14
12
8
6
5
4
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus)
166
107
89
8
7
6
3
3
3
2
2
2
2
2
1
Wirt
Kaninchen
192
4
1
Klonalität
Polyklonal
Konjugat
Dieser PKC zeta Antikörper ist unkonjugiert
9
7
5
4
4
4
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
141
92
88
39
31
15
13
8
6
3
3
2
2
2
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN2775614
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN225191 WB Rabbit IgG N-Term Anmelden zum Anzeigen Polyclonal

General

Antigen Protein Kinase C, zeta (PRKCZ) Antikörper
Epitop N-Term
(41), (31), (17), (14), (12), (8), (6), (5), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus)
(166), (107), (89), (8), (7), (6), (3), (3), (3), (2), (2), (2), (2), (2), (1)
Wirt Kaninchen
(192), (4), (1)
Klonalität
Polyklonal
Konjugat Dieser PKC zeta Antikörper ist unkonjugiert
(9), (7), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Western Blotting (WB)
(141), (92), (88), (39), (31), (15), (13), (8), (6), (3), (3), (2), (2), (2), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-PKC zeta Antikörper

Target Details PKC zeta Anwendungsinformationen Handhabung Referenzen für anti-PKC zeta Antikörper (ABIN2775614) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN982222.
Sequenz MDSVMPSQEP PVDDKNEDAD LPSEETDGIA YISSSRKHDS IKDDSEDLKP
Homologie Cow: 77%, Dog: 75%, Guinea Pig: 75%, Horse: 75%, Human: 100%, Mouse: 92%, Rabbit: 79%, Rat: 92%
Produktmerkmale This is a rabbit polyclonal antibody against PRKCZ. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human PRKCZ

Target Details PKC zeta

Produktdetails anti-PKC zeta Antikörper Anwendungsinformationen Handhabung Referenzen für anti-PKC zeta Antikörper (ABIN2775614) Bilder zurück nach oben
Antigen
Andere Bezeichnung PRKCZ (PRKCZ Antibody Abstract)
Hintergrund Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC.Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: PKC2, PKC-ZETA
Protein Interaction Partner: MAPK7, PRKCZ, AKT2, AKT1, Sqstm1, PARD6A, NUMB, NPM1, HIST1H1B, CFL1, C1QBP, HSP90AA1, NCF1, MARCKS, PPP1R14A, HIST1H1A, UBC, VHL, LRRK2, AJUBA, PARD6B, PAWR, Smurf1, Smurf2, Pard3, HIST3H3, CD44, NCOA3, TFF1, RELA, ESR1, MBP, TRIM41, PIAS4, CCDC115, ZNF7
Protein Size: 409
Molekulargewicht 45 kDa
Gen-ID 5590
NCBI Accession NM_001033581, NP_001028753
UniProt Q05513
Pathways NF-kappaB Signalweg, RTK Signalweg, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling

Anwendungsinformationen

Produktdetails anti-PKC zeta Antikörper Target Details PKC zeta Handhabung Referenzen für anti-PKC zeta Antikörper (ABIN2775614) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 409 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-PKC zeta Antikörper Target Details PKC zeta Anwendungsinformationen Referenzen für anti-PKC zeta Antikörper (ABIN2775614) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PKC zeta Antikörper (ABIN2775614)

Produktdetails anti-PKC zeta Antikörper Target Details PKC zeta Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Xie, Dong, Zhang, Cui, Cohen, Riek, Neumann, Schlattner, Zou: "Activation of protein kinase C zeta by peroxynitrite regulates LKB1-dependent AMP-activated protein kinase in cultured endothelial cells." in: The Journal of biological chemistry, Vol. 281, Issue 10, pp. 6366-75, 2006

Bilder

Produktdetails anti-PKC zeta Antikörper Target Details PKC zeta Anwendungsinformationen Handhabung Referenzen für anti-PKC zeta Antikörper (ABIN2775614) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Protein Kinase C, zeta (PRKCZ) (N-Term) antibody (ABIN2775614) WB Suggested Anti-PRKCZ Antibody Titration: 0.2-1 ug/ml
Positive Control...