anti-Maus p65 Antikörper für Gel Shift

Recommended p65 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Nuclear Factor-KB P65 (NFkBP65) Antikörper
  • NFKB3
  • p65
  • NFkB
  • v-rel avian reticuloendotheliosis viral oncogene homolog A
  • v-rel reticuloendotheliosis viral oncogene homolog A (avian)
  • RELA
  • Rela
Epitop
C-Term
136
72
66
58
51
47
43
40
39
36
33
32
25
21
18
17
16
15
15
13
13
13
12
11
10
9
9
8
7
6
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
1207
676
518
73
59
55
31
30
28
25
15
8
8
6
5
4
2
1
1
Wirt
Kaninchen
1036
147
17
16
11
1
Klonalität
Polyklonal
Konjugat
Dieser p65 Antikörper ist unkonjugiert
34
34
26
21
19
18
16
16
13
13
13
9
9
9
9
9
9
8
8
4
4
3
3
3
2
2
2
2
2
2
1
Applikation
Gel Shift (GS), Western Blotting (WB)
880
429
357
269
224
149
118
88
84
28
22
18
18
11
11
6
6
6
5
4
4
2
2
1
Optionen
Hersteller
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Produktnummer ABIN1043700
157,14 €
Zzgl. Versandkosten 20,00 €, Trockeneispauschale 20,00 € sowie MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN218583 GS IF IHC (p) IP ELISA WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN1738809 GS IF IHC (p) IP ELISA WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN233530 GS IHC (fro) IP ELISA WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN2475874 GS IF IP ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 4
1 ABIN576233 GS IP ELISA WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal

anti-p65 Antikörper für Gel Shift mit den meisten Publikationen

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Applikation / Reaktivität Human Maus Ratte (Rattus)
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General

Antigen Nuclear Factor-KB P65 (NFkBP65) Antikörper
Epitop C-Term
(136), (72), (66), (58), (51), (47), (43), (40), (39), (36), (33), (32), (25), (21), (18), (17), (16), (15), (15), (13), (13), (13), (12), (11), (10), (9), (9), (8), (7), (6), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(1207), (676), (518), (73), (59), (55), (31), (30), (28), (25), (15), (8), (8), (6), (5), (4), (2), (1), (1)
Wirt Kaninchen
(1036), (147), (17), (16), (11), (1)
Klonalität
Polyklonal
Konjugat Dieser p65 Antikörper ist unkonjugiert
(34), (34), (26), (21), (19), (18), (16), (16), (13), (13), (13), (9), (9), (9), (9), (9), (9), (8), (8), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1)
Applikation Gel Shift (GS), Western Blotting (WB)
(880), (429), (357), (269), (224), (149), (118), (88), (84), (28), (22), (18), (18), (11), (11), (6), (6), (6), (5), (4), (4), (2), (2), (1)
Pubmed 8 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-p65 Antikörper

Target Details p65 Anwendungsinformationen Handhabung ProductDetails: References for anti-p65 antibody (ABIN1043700) Bilder
Spezifität This product was prepared from monospecific antiserum by delipidation and defibrination. Anti-NFkB p65 (Rel A) may react non-specifically with other proteins. Control peptide (code #100-4165p) will compete only with the specific reaction of antiserum with the NFkB p65 (Rel A) subunit.
Produktmerkmale Anti NFkB p65 Antibody recognizes NFKB p65 which is a component of NFKB. NFKB was originally identified as a factor that binds to the immunoglobulin kappa light chain enhancer in B cells. It was subsequently found in non-B cells in an inactive cytoplasmic form consisting of NFkappaB bound to IkappaB. NFkappaB was originally identified as a heterodimeric DNA binding protein complex consisting of p65 (RelA) and p50 (NFKB1) subunits. Other identified subunits include p52 (NFKB2), c-Rel, and RelB. The p65, cRel, and RelB subunits are responsible for transactivation. The p50 and p52 subunits possess DNA binding activity but limited ability to transactivate. p52 has been reported to form transcriptionally active heterodimers with the NFkappaB subunit p65, similar to p50/p65 heterodimers. The heterodimers of p52/p65 and p50/p65 are regulated by physical inactivation in the cytoplasm by IkappaBalpha. Ideal for Cardiovascular, Cell Biology, Immunology, Signal Transduction research.
Reinigung Ascites
Sterilität Sterile filtered
Immunogen NFkB p65 (Rel A) peptide corresponding to a region near the C-terminus of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).
Immunogen Type: Peptide

Target Details p65

Produktdetails anti-p65 Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-p65 antibody (ABIN1043700) Bilder zurück nach oben
Antigen
Andere Bezeichnung NFKB p65 (NFkBP65 Antibody Abstract)
Hintergrund Anti NFkB p65 Antibody recognizes NFKB p65 which is a component of NFKB. NFKB was originally identified as a factor that binds to the immunoglobulin kappa light chain enhancer in B cells. It was subsequently found in non-B cells in an inactive cytoplasmic form consisting of NFkappaB bound to IkappaB. NFkappaB was originally identified as a heterodimeric DNA binding protein complex consisting of p65 (RelA) and p50 (NFKB1) subunits. Other identified subunits include p52 (NFKB2), c-Rel, and RelB. The p65, cRel, and RelB subunits are responsible for transactivation. The p50 and p52 subunits possess DNA binding activity but limited ability to transactivate. p52 has been reported to form transcriptionally active heterodimers with the NFkappaB subunit p65, similar to p50/p65 heterodimers. The heterodimers of p52/p65 and p50/p65 are regulated by physical inactivation in the cytoplasm by IkappaBalpha. Ideal for Cardiovascular, Cell Biology, Immunology, Signal Transduction research.
Synonyms: NFKB, nfkb, NF-kB, NF-kappaB, NFkappaB, Nuclear factor NF-kappa-B p65 subunit
Gen-ID 5970, 223468676
Pathways NF-kappaB Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-p65 Antikörper Target Details p65 Handhabung ProductDetails: References for anti-p65 antibody (ABIN1043700) Bilder zurück nach oben
Applikationshinweise Anti-NFkB p65 (Rel A) is suitable for the detection by immunoblot of human and mouse NFkB p65 (Rel A). This product was also tested in a gel supershift assay and found to be reactive against all p65 (Rel A) containing human, mouse or rat NFkB complexes using 0.5 to 1.0 µl per assay.
Kommentare

Gene Name: RELA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-p65 Antikörper Target Details p65 Anwendungsinformationen ProductDetails: References for anti-p65 antibody (ABIN1043700) Bilder zurück nach oben
Format Liquid
Konzentration 80 mg/mL
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
Haltbarkeit 12 months

ProductDetails: References for anti-p65 antibody (ABIN1043700)

Produktdetails anti-p65 Antikörper Target Details p65 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Ghosh, Yang, Rothstein, Robinson: "Nuclear factor-κB contributes to neuron-dependent induction of glutamate transporter-1 expression in astrocytes." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 25, pp. 9159-69, 2011

Yoon, Korade, Carter: "Protein kinase A-induced phosphorylation of the p65 subunit of nuclear factor-kappaB promotes Schwann cell differentiation into a myelinating phenotype." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 28, Issue 14, pp. 3738-46, 2008

Begley, Kasina, Mehra, Adsule, Admon, Lonigro, Chinnaiyan, Macoska: "CXCL5 promotes prostate cancer progression." in: Neoplasia (New York, N.Y.), Vol. 10, Issue 3, pp. 244-54, 2008

Lou, Kaplowitz: "Glutathione depletion down-regulates tumor necrosis factor alpha-induced NF-kappaB activity via IkappaB kinase-dependent and -independent mechanisms." in: The Journal of biological chemistry, Vol. 282, Issue 40, pp. 29470-81, 2007

Cao, Zhang, Edwards, Mosser: "NF-kappaB1 (p50) homodimers differentially regulate pro- and anti-inflammatory cytokines in macrophages." in: The Journal of biological chemistry, Vol. 281, Issue 36, pp. 26041-50, 2006

Poser, Golob, Buettner, Bosserhoff: "Upregulation of HMG1 leads to melanoma inhibitory activity expression in malignant melanoma cells and contributes to their malignancy phenotype." in: Molecular and cellular biology, Vol. 23, Issue 8, pp. 2991-8, 2003

Jobin, Bradham, Russo, Juma, Narula, Brenner, Sartor: "Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 6, pp. 3474-83, 1999

Unlap, Jope: "Dexamethasone attenuates NF-kappa B DNA binding activity without inducing I kappa B levels in rat brain in vivo." in: Brain research. Molecular brain research, Vol. 45, Issue 1, pp. 83-9, 1997

Bilder

Produktdetails anti-p65 Antikörper Target Details p65 Anwendungsinformationen Handhabung ProductDetails: References for anti-p65 antibody (ABIN1043700) zurück nach oben
Bilder des Herstellers
 image for anti-p65 Antikörper (Nuclear Factor-KB P65) (C-Term) (ABIN1043700) anti-Nuclear Factor-KB P65 (NFkBP65) (C-Term) antibody
 image for anti-p65 Antikörper (Nuclear Factor-KB P65) (C-Term) (ABIN1043700) anti-Nuclear Factor-KB P65 (NFkBP65) (C-Term) antibody (Image 2)