NFKBIZ Proteine (NFKBIZ)

Auf www.antikoerper-online.de finden Sie aktuell 5 Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, zeta (NFKBIZ) Proteine von 3 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen NFKBIZ Antikörper (49) und NFKBIZ Kits (3) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 59 NFKBIZ Produkte verfügbar.
Synonyme:
AA408868, IKBZ, INAP, Mail, NFKBIZ, RGD1310834
alle Proteine anzeigen Gen GeneID UniProt
Ratte NFKBIZ NFKBIZ 304005  
NFKBIZ 80859 Q9EST8
NFKBIZ 64332 Q9BYH8

NFKBIZ Proteine (NFKBIZ) nach Spezies

Weitere Proteine zu NFKBIZ Interaktionspartnern

Mouse (Murine) Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, zeta (NFKBIZ) Interaktionspartner

  1. In cultured macrophages, LPS (zeige TLR4 Proteine)-induced expression of monocyte chemoattractant protein (MCP)-1 (zeige CPT1B Proteine) was suppressed by NaN3 through inhibition of STAT1 (zeige STAT1 Proteine) and IkappaBzeta activities.

  2. Data show that I-kappa-B-zeta (IkappaBzeta) regulates macrophage interleukin-10 (zeige IL10 Proteine) (IL_10) expression by directly activated the Il-10 (zeige IL10 Proteine) promoter.

  3. A possible important role of Nfkbiz in modulating the progression of inflammatory diseases in which IFN-gamma (zeige IFNG Proteine) and IL-1 (zeige IL1A Proteine) are abundant.

  4. Nfkbiz-/- keratinocytes were hypoproliferative. In skin from Nfkbiz-/- mice, the expression of the keratinocyte differentiation markers K10 (zeige KRT10 Proteine) and filaggrin (zeige FLG Proteine) were reduced, although that of K14 (zeige KRT14 Proteine) was unchanged.

  5. These data reveal a previously unappreciated role for IkappaB-zeta in IFN-gamma (zeige IFNG Proteine) production in T cells and the immunoregulatory function of T regulatory cells.

  6. The pyrimidine-rich IkappaBzeta-responsive site plays an essential role in productive interaction of IkappaBzeta with the p50 (zeige LSP1 Proteine)-DNA complex.

  7. IkappaB-zeta regulates TLR-mediated CSR by inducing AID

  8. The IkappaB-zeta-Akirin2 (zeige AKIRIN2 Proteine)-BAF60 complex physically links the NF-kappaB (zeige NFKB1 Proteine) and SWI (zeige SMARCA1 Proteine)/SNF (zeige SNRPA Proteine) complexes in innate immune cell activation.

  9. The IkappaB-zeta-deficient B cells exhibited impaired proliferation and enhanced up-regulation of CD86 (zeige CD86 Proteine) following stimulation of TLR9 (zeige TLR9 Proteine), but not the BCR (zeige BCR Proteine), indicating critical roles for IkappaB-zeta in TLR signaling in B cells.

  10. IkappaBzeta-deficient mice showed significantly impaired CCL2 (zeige CCL2 Proteine) secretion.

Human Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, zeta (NFKBIZ) Interaktionspartner

  1. In cultured macrophages, LPS (zeige IRF6 Proteine)-induced expression of monocyte chemoattractant protein (MCP)-1 (zeige CCL2 Proteine) was suppressed by NaN3 through inhibition of STAT1 (zeige STAT1 Proteine) and IkappaBzeta activities.

  2. IkappaB-zeta regulates human monocyte pro-inflammatory responses induced by Streptococcus pneumoniae.

  3. TNF-alpha (zeige TNF Proteine)- and IL-17A (zeige IL17A Proteine) mediate synergistic induction of DEFB4 (zeige DEFB104A Proteine) gene expression in human keratinocytes through IkappaBzeta

  4. We propose a previously unappreciated role of IkappaBzeta in the inflammatory micromilieu as well as progression in glioma

  5. These results indicate that the LPS (zeige IRF6 Proteine)/IL-1beta (zeige IL1B Proteine)-MyD88 (zeige MYD88 Proteine) axis plays a crucial role for stabilization of IkappaB-zeta mRNA.

  6. Interferon-gamma (IFN-gamma (zeige IFNG Proteine)) interferes with the IL-1 (zeige IL1A Proteine)/IKB-zeta axis in beta-glucan-activated dendritic cells and promotes T cell-mediated immune responses with increased release of IFN-gamma (zeige IFNG Proteine) and IL-22 (zeige IL22 Proteine).

  7. NFKBIZ gene knockdown in bronchial epithelial cells suppresses the release of IL-1b (zeige IL1B Proteine)-induced IL-6 (zeige IL6 Proteine) and GMCSF (zeige CSF2 Proteine).

  8. IkappaBzeta functions as an important regulator of IFN-gamma (zeige IFNG Proteine) in human NK cells

  9. NF-kappaB (zeige NFKB1 Proteine)-binding cofactor inhibitor of NF-kappaB (zeige NFKB1 Proteine)-zeta (IkappaB-zeta) is constitutively expressed in HTLV-I-infected T cell lines and ATL cells, and Tax (zeige CNTN2 Proteine) transactivates the IkappaB-zeta gene, mainly through NF-kappaB (zeige NFKB1 Proteine).

  10. our data demonstrate that IkappaB-zeta is essential for nuclear NF-kappaB (zeige NFKB1 Proteine) activity in activated B-cell-like subtype of diffuse large B-cell lymphoma

NFKBIZ Protein Überblick

Protein Überblick

This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with NFKBIZ

  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta (Nfkbiz)
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta (NFKBIZ)
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta (nfkbiz)
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta (LOC100356473)
  • nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta (Nfkbiz)
  • AA408868 Protein
  • IKBZ Protein
  • INAP Protein
  • Mail Protein
  • NFKBIZ Protein
  • RGD1310834 Protein

Bezeichner auf Proteinebene für NFKBIZ

IkappaB-zeta , NF-kappa-B inhibitor zeta , nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta , molecule associated with ankyrin repeats induced by lipopolysaccharide , NF-kappa-B inhibitor zeta-like , I-kappa-B-zeta , IL-1 inducible nuclear ankyrin-repeat protein , ikB-zeta , ikappaBzeta , molecule possessing ankyrin repeats induced by lipopolysaccharide , molecule possessing ankyrin-repeats induced by lipopolysaccharide , Ikappa B-zeta variant 3 , molecule possessing ankyrin repeats induced by lipopolysaccharide (MAIL), homolog of mouse

GENE ID SPEZIES
304005 Rattus norvegicus
418404 Gallus gallus
460564 Pan troglodytes
478549 Canis lupus familiaris
702846 Macaca mulatta
100001781 Danio rerio
100012533 Monodelphis domestica
100034245 Equus caballus
100089070 Ornithorhynchus anatinus
100170483 Xenopus (Silurana) tropicalis
100356473 Oryctolagus cuniculus
100456330 Pongo abelii
100562077 Anolis carolinensis
100597177 Nomascus leucogenys
80859 Mus musculus
64332 Homo sapiens
282713 Bos taurus
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