anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) Antikörper

Bezeichnung:
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 Antikörper (NFKB2)
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Synonyme:
H2TF1, lyt, LYT-10, LYT10, NF-kappaB2, NF-kB2, p49, p49/p100, p50B, p52, p100, p105, RGD1307189, wu:fa03b02, zgc:136693
Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Maus NFKB2 NFKB2 18034 Q9WTK5
Anti-Human NFKB2 NFKB2 4791 Q00653
Anti-Ratte NFKB2 NFKB2 309452  

Weitere Synonyme anzeigen

Weitere Antikörper gegen Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 Interaktionspartner

Mouse (Murine) Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) Interaktionspartner

  1. MKK4 (zeige MAP2K4 Antikörper) activates non-canonical NFkappaB signaling by promoting NFkappaB2-p100 (zeige PATL2 Antikörper) processing.

  2. the aberrant proliferative capacity of Brca1 (zeige BRCA1 Antikörper)(-/-) luminal progenitor cells is linked to the replication-associated DNA damage response, where proliferation of mammary progenitors is perpetuated by damage-induced, autologous NF-kappaB (zeige NFKB1 Antikörper) signaling.

  3. RelB (zeige RELB Antikörper) is processed by CO2 in a manner dependent on a key C-terminal domain located in its transactivation domain. Loss of the RelB (zeige RELB Antikörper) transactivation domain alters NF-kappaB (zeige NFKB1 Antikörper)-dependent transcriptional activity, and loss of p100 (zeige PATL2 Antikörper) alters sensitivity of RelB (zeige RELB Antikörper) to CO2

  4. the individual functions of the NF-kappaB (zeige NFKB1 Antikörper) family members NF-kappaB1 (zeige NFKB1 Antikörper), NF-kappaB2 and c-REL (zeige NFkBP65 Antikörper) in the various autoimmune pathologies of Fas(lpr/lpr (zeige FAS Antikörper)) mutant mice, were investigated.

  5. we identify in this study a critical role for the combined activity of the RELB (zeige RELB Antikörper) and NF-kappaB2 subunits in B cell homeostasis that cannot be compensated for by the canonical NF-kappaB (zeige NFKB1 Antikörper) pathway under physiological conditions.

  6. Mechanistically the LncRNA-HIT siRNA treatments impacted pro-chondrogenic gene expression by reducing H3K27ac or p100 (zeige PATL2 Antikörper) activity, confirming that LncRNA-HIT is essential for chondrogenic differentiation in the limb mesenchyme

  7. Nfkb2 connected lymphotoxin (zeige LTB Antikörper) signal within the intestinal niche in reinforcing epithelial innate inflammatory RelA (zeige NFkBP65 Antikörper)/NF-kappaB (zeige NFKB1 Antikörper) response to Citrobacter rodentium infection, while Nfkb2(-/-) mice succumbed to gut (zeige GUSB Antikörper) infections owing to stromal defects.

  8. Data indicate a coupled increase in the expression of renal, relA (zeige NFkBP65 Antikörper), NF-kB2, and p53 (zeige TP53 Antikörper) genes and proteins during folic acid induced acute kidney injury (AKI).

  9. Loss of c-REL (zeige NFkBP65 Antikörper) but not NF-kappaB2 prevents autoimmune disease driven by FasL (zeige FASL Antikörper) mutation.

  10. NF-kappaB2/p52 is necessary for the development of colitis, whilst c-Rel (zeige NFkBP65 Antikörper)-mediated signalling regulates colonic epithelial cell turnover following DNA damage.

Human Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) Interaktionspartner

  1. Findings identify specific roles for p100 (zeige CUX1 Antikörper) and p105 (zeige CDH13 Antikörper) signaling in defining DLBCL molecular subtypes and posit MYD88 (zeige MYD88 Antikörper)/p100 (zeige CUX1 Antikörper) signaling as a regulator for B-cell activation (zeige BLNK Antikörper).

  2. a new ERK2 (zeige MAPK1 Antikörper)/AP-1 (zeige FOSB Antikörper)/miR (zeige MLXIP Antikörper)-494/PTEN (zeige PTEN Antikörper) pathway that is responsible for the tumor-suppressive role of NFkappaB2 p100 (zeige CUX1 Antikörper) in cellular transformation.

  3. MKK4 (zeige MAP2K4 Antikörper) activates non-canonical NFkappaB (zeige NFKB1 Antikörper) signaling by promoting NFkappaB2-p100 (zeige CUX1 Antikörper) processing.

  4. the aberrant proliferative capacity of Brca1(-/-) luminal progenitor cells is linked to the replication-associated DNA damage response, where proliferation of mammary progenitors is perpetuated by damage-induced, autologous NF-kappaB (zeige NFKB1 Antikörper) signaling.

  5. RelB (zeige RELB Antikörper) is processed by CO2 in a manner dependent on a key C-terminal domain located in its transactivation domain. Loss of the RelB (zeige RELB Antikörper) transactivation domain alters NF-kappaB (zeige NFKB1 Antikörper)-dependent transcriptional activity, and loss of p100 (zeige CUX1 Antikörper) alters sensitivity of RelB (zeige RELB Antikörper) to CO2

  6. The expression levels of BRAFV600E and NF-kappaB (zeige NFKB1 Antikörper) were significantly greater in thyroglobuiln antibody-positive than in thyroglobuiln antibody-negative papillary thyroid carcinoma patients.

  7. Gene expression levels of NF-kappaB2 were deregulated in 49 B-cell chronic lymphocytic leukemia, 8 B-cell non-Hodgkin's lymphoma, 3 acute myeloid leukemia, 3 chronic myeloid leukemia, 2 hairy cell leukemia, 2 myelodysplastic syndrome, and 2 T-cell large granular lymphocytic leukemia patients in the post-Chernobyl period.

  8. melatonin transcriptionally inhibited MMP-9 (zeige MMP9 Antikörper) by reducing p65 (zeige GORASP1 Antikörper)- and p52 (zeige FKBP4 Antikörper)-DNA-binding activities. Moreover, the Akt (zeige AKT1 Antikörper)-mediated JNK1 (zeige MAPK8 Antikörper)/2 and ERK1/2 (zeige MAPK1/3 Antikörper) signaling pathways were involved in melatonin-regulated MMP-9 (zeige MMP9 Antikörper) transactivation and cell motility.

  9. we observed an association of FBW7 (zeige FBXW7 Antikörper) with p105 (zeige CDH13 Antikörper) and p65 (zeige GORASP1 Antikörper), as well as p100 (zeige CUX1 Antikörper), and knockdown of FBW7 (zeige FBXW7 Antikörper) eliminated 1,25D-dependent subunit turnover.

  10. results suggest that glucocorticoids induce a transcription complex consisting of RelB (zeige RELB Antikörper)/p52 (zeige FKBP4 Antikörper), CBP (zeige CREBBP Antikörper), and HDAC1 (zeige HDAC1 Antikörper) that triggers a dynamic acetylation-mediated epigenetic change to induce CRH (zeige CRH Antikörper) expression in full-term human placenta.

Zebrafish Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) Interaktionspartner

  1. Study indicates an essential role of NF-kappaB (zeige NFKB1 Antikörper) in gonadal differentiation

Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) Antigen-Profil

Beschreibung des Gens

This gene encodes one of the subunits of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB transcription factor complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The NFkB complex can consist of different subunits that form both homo- or heterodimers which bind specific kappa-B elements in target genes. This gene encodes the p100 subunit that is processed into the active p52 subunit. This protein can function as both a transcriptional activator and repressor, depending on its dimer partner. Alternate splicing results in both coding and non-coding variants.

Alternative names and synonyms associated with Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2)

  • nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 (Nfkb2) Antikörper
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) (NFKB2) Antikörper
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) (nfkb2) Antikörper
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 (Nfkb2) Antikörper
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 (nfkb2) Antikörper
  • H2TF1 Antikörper
  • lyt Antikörper
  • LYT-10 Antikörper
  • LYT10 Antikörper
  • NF-kappaB2 Antikörper
  • NF-kB2 Antikörper
  • p49 Antikörper
  • p49/p100 Antikörper
  • p50B Antikörper
  • p52 Antikörper
  • p100 Antikörper
  • p105 Antikörper
  • RGD1307189 Antikörper
  • wu:fa03b02 Antikörper
  • zgc:136693 Antikörper

Bezeichner auf Proteinebene für NFKB2

DNA-binding factor KBF2 , NF kappaB2 , nuclear factor NF-kappa-B p100 subunit , nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 , lymphocyte translocation chromosome 10 protein , nuclear factor of kappa light chain gene enhancer in B-cells 2 , oncogene Lyt-10 , lyt-10 , nuclear factor NF-kappa-B p97 subunit , p100-NFkappaB2 , NF-kB2-I precursor protein , NF-kB2-II precursor protein , P100/P52 transcription factor

GENE ID SPEZIES
18034 Mus musculus
4791 Homo sapiens
526392 Bos taurus
386574 Gallus gallus
486858 Canis lupus familiaris
397698 Xenopus laevis
309452 Rattus norvegicus
415100 Danio rerio
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