MYD88 (MYD88) ELISA Kits

Bezeichnung:
Myeloid Differentiation Primary Response Gene (88) ELISA Kits (MYD88)
Auf www.antikoerper-online.de finden Sie aktuell 44 Myeloid Differentiation Primary Response Gene (88) (MYD88) ELISA Kits von 12 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MYD88 Antikörper (272) und MYD88 Proteine (26) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 363 MYD88 Produkte verfügbar.
Synonyme:
CG2078, Dmel\\CG2078, DmMyd88, dMyd88, EP(2)2535, GB12344, irak-2, kra, LD20892, MGC84928, myd88, myd88d, Myd88F, NV10640, XMyD88, zgc:103541

Am meisten referenzierte MYD88 ELISA Kits

  1. Human MYD88 ELISA Kit für Sandwich ELISA - ABIN1672854 : Bonnert, Garka, Parnet, Sonoda, Testa, Sims: The cloning and characterization of human MyD88: a member of an IL-1 receptor related family. in FEBS letters 1997 (PubMed)

Weitere ELISA Kits für MYD88 Interaktionspartner

Fruit Fly (Drosophila melanogaster) Myeloid Differentiation Primary Response Gene (88) (MYD88) Interaktionspartner

  1. a novel function of MyD88 in the regulation of metabolism that appears to be independent of its known roles in immunity and development.

  2. propose that dMyD88 is the functional homolog of TIRAP (zeige TIRAP ELISA Kits) and that both proteins function as sorting adaptors to recruit downstream signaling adaptors to activated receptors

  3. DmMyD88 encodes an essential component of the Toll (zeige TLR4 ELISA Kits) pathway in dorsoventral pattern formation.

  4. We show that there is a direct interaction between Kra and Tube presumably mediated by the death domains present in both proteins.

  5. both the heterodimeric and heterotrimeric complexes form kidney-shaped structures and that Tube is bivalent and has separate high affinity binding sites for dMyD88 and Pelle (zeige IRAK1 ELISA Kits).

Zebrafish Myeloid Differentiation Primary Response Gene (88) (MYD88) Interaktionspartner

  1. Fish IRF6 (zeige IRF6 ELISA Kits) is distinguished from the homolog of mammals by being a positive regulator of IFN transcription and phosphorylated by MyD88 and TBK1 (zeige TBK1 ELISA Kits), suggesting that differences in the IRF6 (zeige IRF6 ELISA Kits) regulation pattern exist between lower and higher vertebrates.

  2. DrIRF1 works in concert with MyD88 to activate zebrafish IFNvarphi3 but not IFNvarphi1. These results provide insights into the evolving function of IRF1 (zeige IRF1 ELISA Kits) as a positive IFN regulator.

  3. MyD88 signaling has an important protective role during early pathogenesis.

  4. MyD88-dependent signaling is involved in the innate immune response of the developing zebrafish embryo, a model for the study of vertebrate innate immunity.

Human Myeloid Differentiation Primary Response Gene (88) (MYD88) Interaktionspartner

  1. Here the authors show that MAL (zeige MAL ELISA Kits) TIR domains spontaneously and reversibly form filaments in vitro. They also form cofilaments with TLR4 (zeige TLR4 ELISA Kits) TIR domains and induce formation of MyD88 assemblies.

  2. data show that in pericytes, MyD88 and IRAK4 (zeige IRAK4 ELISA Kits) are key regulators of 2 major injury responses: inflammatory and fibrogenic.

  3. Data indicate that 64 patients (57.1%) carried the myeloid differentiation factor 88 protein (MYD88) L265P mutation and 14 patients (12.5%) carried the chemokine (C-X-C motif) receptor 4 (CXCR4) WHIM (zeige CXCR4 ELISA Kits)-like mutation.

  4. HCK (zeige HCK ELISA Kits) represents a novel target for therapeutic development in MYD88-mutated Waldenstrom macroglobulinemia and activated-B cell diffuse large B-cell lymphoma, and possibly other diseases driven by mutated MYD88.

  5. We found an that enhanced expression of the TLR4 (zeige TLR4 ELISA Kits)-MyD88-NF-kB pathway occurs in GDM placentae, which positively correlates with heightened local IR in placentae and higher maternal hyperglycemia. The TLR4 (zeige TLR4 ELISA Kits)/MyD88/NF-kB pathway may play a potential role in the development of IR in placentae of GDM.

  6. We found that over-expression of CRNDE in astrocytes increased the expression of key factors in the toll (zeige TLR4 ELISA Kits)-like receptor signaling pathway, especially toll-like receptor-3 (zeige TLR3 ELISA Kits)-mediated MyD88-independent pathway.We speculated that CRNDE might trigger inflammation to regulate tumorigenesis and tumor development through the toll (zeige TLR4 ELISA Kits)-like receptor pathway

  7. Data suggest that, in monocytes and macrophages, the interleukin-1B- (IL1B (zeige IL1B ELISA Kits))-stimulated trans-autophosphorylation of IRAK4 (interleukin-1 receptor-associated kinase 4 (zeige IRAK4 ELISA Kits)) is initiated by MYD88-induced dimerization of IRAK4 (zeige IRAK4 ELISA Kits). In contrast, IRAK1 (interleukin-1 receptor-associated kinase 1 (zeige IRAK1 ELISA Kits)) is inactive in unstimulated monocytes/macrophages and is converted to an active protein kinase (zeige CDK7 ELISA Kits) in response to IL1B (zeige IL1B ELISA Kits).

  8. our data suggest a new role of MyD88 in the development of glucose intolerance and hepatic steatosis.

  9. In patient population from Southeast Serbia Myd 88 L265 mutation was not responsible for the development of diffuse large B-cell non Hodgkin lymphoma.

  10. FSTL1 (zeige FSTL1 ELISA Kits) displays anti-inflammatory effects against oxidized low-density lipoprotein-induced pro-inflammatory cytokine production via a mechanism that involves the TLR4 (zeige TLR4 ELISA Kits)/MyD88/NF-kappaB (zeige NFKB1 ELISA Kits) and MAPK (zeige MAPK1 ELISA Kits) signaling pathways.

Pig (Porcine) Myeloid Differentiation Primary Response Gene (88) (MYD88) Interaktionspartner

  1. These results suggest that porcine circovirus 2 induces IL-8 (zeige IL8 ELISA Kits) secretion via the TLR2 (zeige TLR2 ELISA Kits)/MyD88/NF-kappaB (zeige NFKB1 ELISA Kits) signalling pathway.

  2. At 30 days after autotransplantation of a pig kidney, mRNA expression increases for MyD88.

  3. These results suggest that an MyD88-dependent signaling pathway is present in newborn as well as in adult swine and that it is involved in the innate immune system of these animals.

Cow (Bovine) Myeloid Differentiation Primary Response Gene (88) (MYD88) Interaktionspartner

  1. L. rhamnosus GR-1 ameliorates the E. coli-induced disruption of cellular ultrastructure, subsequently reducing the percentage of bovine endometrial epithelial cells apoptosis and limiting inflammatory responses, partly via attenuation of MyD88-dependent and MyD88-independent pathway activation

  2. Modulated cytokine expression in Bovine viral diarrhea virus type 2 infected macrophages was associated with decreased MyD88 expression.

  3. The study demonstrates that in cattle, animals heterozygous at the MyD88 A625C polymorphic marker have a 5-fold reduced risk for active pulmonary tuberculosis.

  4. MyD88 plays a functional role in transducing LPS (zeige IRF6 ELISA Kits) signaling from TLR-4 (zeige TLR4 ELISA Kits) to downstream effector molecules involved in NF-kappaB (zeige NFKB1 ELISA Kits) activation

Atlantic Salmon (Salmo salar) Myeloid Differentiation Primary Response Gene (88) (MYD88) Interaktionspartner

  1. MyD88 interacts with interferon (zeige IFNA ELISA Kits) regulatory factor (IRF) 3 (zeige IRF3 ELISA Kits) and IRF7 (zeige IRF7 ELISA Kits) in Atlantic salmon (Salmo salar)

  2. the salmon MyD88 was cloned and its expression was analysed.

Mouse (Murine) Myeloid Differentiation Primary Response Gene (88) (MYD88) Interaktionspartner

  1. These data show that the normal distribution of surface glycosylation requires IL-1R, but not MyD88, and is not sufficient to prevent bacterial binding.

  2. data show that in pericytes, MyD88 and IRAK4 (zeige IRAK4 ELISA Kits) are key regulators of 2 major injury responses: inflammatory and fibrogenic.

  3. TLR4 (zeige TLR4 ELISA Kits) agonist MPLA potently induced MyD88-dependent signaling. Neutrophil recruitment after multiple injections of MPLA was reliant on MyD88-dependent signaling. MPLA treatment induced expansion of myeloid progenitors in bone marrow and upregulation of CD11b (zeige ITGAM ELISA Kits) and shedding of L-selectin (zeige SELL ELISA Kits) by neutrophils, all of which were attenuated in MyD88-deficient mice.

  4. Autophagy contributes to macrophage resistance to Leishmania major. Data, including data from studies in knockout mice, suggest a key resistance mechanism involves endosomal signaling via Tlr3 (zeige TLR3 ELISA Kits)/7/9 in macrophages; macrophages deficient for Tlr3 (zeige TLR3 ELISA Kits)/7/9, Unc93b1 (zeige UNC93B1 ELISA Kits), or MyD88 fail to undergo L. major-induced autophagy. (TLR = Toll (zeige TLR4 ELISA Kits)-like receptor; Unc93b1 (zeige UNC93B1 ELISA Kits) = unc-93 (zeige UNC93B1 ELISA Kits) homolog B1; MyD88 = myeloid differentiation primary response gene 88)

  5. MyD88 inhibitor ST2825 attenuates acute cardiac rejection and promotes donor-specific hyporesponsiveness in stringent skin transplant models

  6. MyD88 has a divergent requirement for cell survival in non-Tregs and Tregs, and a yet-to-be defined survival-independent requirement for Treg function during the response to alloantigen

  7. The aim of this study was to examine the role of the common TLR adaptor protein myeloid-differentiation factor (MyD) 88 in lung epithelium during host defense against K. pneumoniae-induced pneumonia.

  8. TLR2 (zeige TLR2 ELISA Kits), TLR4 (zeige TLR4 ELISA Kits) AND MyD88 mediate allergic airway disease (AAD) and Streptococcus pneumoniae-induced suppression of AAD.

  9. miR (zeige MLXIP ELISA Kits)-23a-5p modulated the innate host defense by promoting mycobacteria survival and inhibiting the activation of autophagy against Mycobacterium tuberculosis through TLR2 (zeige TLR2 ELISA Kits)/MyD88/NF-kappaB (zeige NFKB1 ELISA Kits) pathway by targeting TLR2 (zeige TLR2 ELISA Kits).

  10. results indicate that the R753Q polymorphism alters TLR2 (zeige TLR2 ELISA Kits) signaling competence, leading to impaired MyD88-TLR2 (zeige TLR2 ELISA Kits) assembly, reduced phosphorylation of IRAK-1 (zeige IRAK1 ELISA Kits), diminished activation of MAPKs and NF-kappaB (zeige NFKB1 ELISA Kits), and deficient induction of cytokines in macrophages infected with M. smegmatis.

MYD88 Antigen-Profil

Beschreibung des Gens

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with MYD88

  • myeloid differentiation primary response 88 (MYD88) Elisa Kit
  • interleukin-1 receptor-associated kinase 2 (irak2) Elisa Kit
  • interleukin-1 receptor-associated kinase 2 (IRAK2) Elisa Kit
  • interleukin-1 receptor-associated kinase 2 (LOC100228175) Elisa Kit
  • myeloid differentiation primary response gene (88) (myd88-b) Elisa Kit
  • myeloid differentiation primary response gene 88 (Myd88) Elisa Kit
  • CG2078 gene product from transcript CG2078-RB (Myd88) Elisa Kit
  • myeloid differentiation primary response 88 (Myd88) Elisa Kit
  • myeloid differentiation primary response gene (88) (MYD88) Elisa Kit
  • myeloid differentiation primary response gene (88) (myd88) Elisa Kit
  • myeloid differentiation primary response factor 88 (Myd88) Elisa Kit
  • myeloid differentiation primary response 88 (myd88) Elisa Kit
  • MyD88 adaptor (myd88) Elisa Kit
  • myeloid differentiation factor 88 (myd88) Elisa Kit
  • myeloid differentiation response protein 88 (myd88) Elisa Kit
  • myeloid differentiation primary response gene 88 (myd88) Elisa Kit
  • CG2078 Elisa Kit
  • Dmel\\CG2078 Elisa Kit
  • DmMyd88 Elisa Kit
  • dMyd88 Elisa Kit
  • EP(2)2535 Elisa Kit
  • GB12344 Elisa Kit
  • irak-2 Elisa Kit
  • kra Elisa Kit
  • LD20892 Elisa Kit
  • MGC84928 Elisa Kit
  • myd88 Elisa Kit
  • myd88d Elisa Kit
  • Myd88F Elisa Kit
  • NV10640 Elisa Kit
  • XMyD88 Elisa Kit
  • zgc:103541 Elisa Kit

Bezeichner auf Proteinebene für MYD88

myeloid differentiation primary response gene (88) , myeloid differentiation primary response protein MyD88 , interleukin-1 receptor-associated kinase-like 2 , interleukin-1 receptor-associated kinase 2 , myeloid differentiation primary response protein MyD88-B , Toll/IL-1 receptor binding protein MyD88-B , CG2078-PA , CG2078-PB , Myd88-PA , Myd88-PB , Myd88F , krapfen , myeloid differentiation primary response gene 88 , myeloid differentiation primary response factor 88 , zMyD88 , myeloid differentiation factor 88 , myeloid differentiation primary response protein 88 , myeloid differentiation response protein 88

GENE ID SPEZIES
4615 Homo sapiens
493227 Xenopus (Silurana) tropicalis
416118 Gallus gallus
100228175 Taeniopygia guttata
734302 Xenopus laevis
17874 Mus musculus
35956 Drosophila melanogaster
301059 Rattus norvegicus
396646 Sus scrofa
403145 Danio rerio
413194 Apis mellifera
420420 Gallus gallus
444881 Bos taurus
460269 Pan troglodytes
477024 Canis lupus familiaris
549591 Xenopus (Silurana) tropicalis
678682 Ovis aries
696494 Macaca mulatta
100118553 Nasonia vitripennis
100134853 Takifugu rubripes
100136123 Oncorhynchus mykiss
100169859 Salmo salar
100305041 Ictalurus punctatus
100616081 Amphimedon queenslandica
575153 Strongylocentrotus purpuratus
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