anti-MYD88 (MYD88) Antikörper

Bezeichnung:
anti-Myeloid Differentiation Primary Response Gene (88) Antikörper (MYD88)
Auf www.antikoerper-online.de finden Sie aktuell 272 Myeloid Differentiation Primary Response Gene (88) (MYD88) Antikörper von 35 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MYD88 Kits (44) und MYD88 Proteine (26) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 363 MYD88 Produkte verfügbar.
Synonyme:
CG2078, Dmel\\CG2078, DmMyd88, dMyd88, EP(2)2535, GB12344, irak-2, kra, LD20892, MGC84928, myd88, myd88d, Myd88F, NV10640, XMyD88, zgc:103541

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Am meisten referenzierte anti-MYD88 Antikörper

  1. Human Polyclonal MYD88 Primary Antibody für EIA, WB - ABIN401364 : Adachi, Kawai, Takeda, Matsumoto, Tsutsui, Sakagami, Nakanishi, Akira: Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function. in Immunity 1998 (PubMed)
    Zeige alle 5 Referenzen für 401364

  2. Human Polyclonal MYD88 Primary Antibody für IF (p), IHC (p) - ABIN736881 : Lu, Liu, Gu, Ge, Wu, Ze-Ji, Qiu, Zhang, Chao, Yu: Gene Expression Profiles Underlying Selective T-Cell-Mediated Immunity Activity of a Chinese Medicine Granule on Mice Infected with Influenza Virus H1N1. in Evidence-based complementary and alternative medicine : eCAM 2014 (PubMed)
    Zeige alle 5 Referenzen für 736881

  3. Human Polyclonal MYD88 Primary Antibody für ICC, IF - ABIN446974 : Mijares, Wangdi, Sokol, Homer, Medzhitov, Kazmierczak: Airway epithelial MyD88 restores control of Pseudomonas aeruginosa murine infection via an IL-1-dependent pathway. in Journal of immunology (Baltimore, Md. : 1950) 2011 (PubMed)
    Zeige alle 2 Referenzen für 446974

  4. Human Polyclonal MYD88 Primary Antibody für EIA, WB - ABIN453754 : Bannon, Davies, Collett, Warhurst: Potentiation of flagellin responses in gut epithelial cells by interferon-gamma is associated with STAT-independent regulation of MyD88 expression. in The Biochemical journal 2009 (PubMed)
    Zeige alle 2 Referenzen für 453754

  5. Human Monoclonal MYD88 Primary Antibody für FACS, IF - ABIN2453996 : Choi, Kim, Lee, Kim: MYD88 expression and L265P mutation in diffuse large B-cell lymphoma. in Human pathology 2013 (PubMed)
    Zeige alle 2 Referenzen für 2453996

  6. Human Polyclonal MYD88 Primary Antibody für FACS, IHC (p) - ABIN652460 : Deng, Yuan, Guo, Zhu, Pan, Liu: Efficacy of atorvastatin on hippocampal neuronal damage caused by chronic intermittent hypoxia: involving TLR4 and its downstream signaling pathway. in Respiratory physiology & neurobiology 2015 (PubMed)
    Zeige alle 2 Referenzen für 652460

  7. Human Polyclonal MYD88 Primary Antibody für WB - ABIN809502 : Abe, Hirasaka, Kagawa, Kohno, Ochi, Utsunomiya, Sakai, Ohno, Teshima-Kondo, Okumura, Oarada, Maekawa, Terao, Mills, Nikawa: Cbl-b is a critical regulator of macrophage activation associated with obesity-induced insulin resistance in mice. in Diabetes 2013 (PubMed)

  8. Dog (Canine) Polyclonal MYD88 Primary Antibody für WB - ABIN2786657 : Dhiman, Ovsyannikova, Vierkant, Ryan, Pankratz, Jacobson, Poland: Associations between SNPs in toll-like receptors and related intracellular signaling molecules and immune responses to measles vaccine: preliminary results. in Vaccine 2008 (PubMed)

  9. Human Polyclonal MYD88 Primary Antibody für IHC, ELISA - ABIN185362 : Li, Qin: Modulation of Toll-interleukin 1 receptor mediated signaling. in Journal of molecular medicine (Berlin, Germany) 2005 (PubMed)

Weitere Antikörper gegen MYD88 Interaktionspartner

Fruit Fly (Drosophila melanogaster) Myeloid Differentiation Primary Response Gene (88) (MYD88) Interaktionspartner

  1. a novel function of MyD88 in the regulation of metabolism that appears to be independent of its known roles in immunity and development.

  2. propose that dMyD88 is the functional homolog of TIRAP (zeige TIRAP Antikörper) and that both proteins function as sorting adaptors to recruit downstream signaling adaptors to activated receptors

  3. DmMyD88 encodes an essential component of the Toll (zeige TLR4 Antikörper) pathway in dorsoventral pattern formation.

  4. We show that there is a direct interaction between Kra and Tube presumably mediated by the death domains present in both proteins.

  5. both the heterodimeric and heterotrimeric complexes form kidney-shaped structures and that Tube is bivalent and has separate high affinity binding sites for dMyD88 and Pelle (zeige IRAK1 Antikörper).

Zebrafish Myeloid Differentiation Primary Response Gene (88) (MYD88) Interaktionspartner

  1. Fish IRF6 (zeige IRF6 Antikörper) is distinguished from the homolog of mammals by being a positive regulator of IFN transcription and phosphorylated by MyD88 and TBK1 (zeige TBK1 Antikörper), suggesting that differences in the IRF6 (zeige IRF6 Antikörper) regulation pattern exist between lower and higher vertebrates.

  2. DrIRF1 works in concert with MyD88 to activate zebrafish IFNvarphi3 but not IFNvarphi1. These results provide insights into the evolving function of IRF1 (zeige IRF1 Antikörper) as a positive IFN regulator.

  3. MyD88 signaling has an important protective role during early pathogenesis.

  4. MyD88-dependent signaling is involved in the innate immune response of the developing zebrafish embryo, a model for the study of vertebrate innate immunity.

Human Myeloid Differentiation Primary Response Gene (88) (MYD88) Interaktionspartner

  1. Here the authors show that MAL (zeige MAL Antikörper) TIR domains spontaneously and reversibly form filaments in vitro. They also form cofilaments with TLR4 (zeige TLR4 Antikörper) TIR domains and induce formation of MyD88 assemblies.

  2. data show that in pericytes, MyD88 and IRAK4 (zeige IRAK4 Antikörper) are key regulators of 2 major injury responses: inflammatory and fibrogenic.

  3. Data indicate that 64 patients (57.1%) carried the myeloid differentiation factor 88 protein (MYD88) L265P mutation and 14 patients (12.5%) carried the chemokine (C-X-C motif) receptor 4 (CXCR4) WHIM (zeige CXCR4 Antikörper)-like mutation.

  4. HCK (zeige HCK Antikörper) represents a novel target for therapeutic development in MYD88-mutated Waldenstrom macroglobulinemia and activated-B cell diffuse large B-cell lymphoma, and possibly other diseases driven by mutated MYD88.

  5. We found an that enhanced expression of the TLR4 (zeige TLR4 Antikörper)-MyD88-NF-kB pathway occurs in GDM placentae, which positively correlates with heightened local IR in placentae and higher maternal hyperglycemia. The TLR4 (zeige TLR4 Antikörper)/MyD88/NF-kB pathway may play a potential role in the development of IR in placentae of GDM.

  6. We found that over-expression of CRNDE in astrocytes increased the expression of key factors in the toll (zeige TLR4 Antikörper)-like receptor signaling pathway, especially toll-like receptor-3 (zeige TLR3 Antikörper)-mediated MyD88-independent pathway.We speculated that CRNDE might trigger inflammation to regulate tumorigenesis and tumor development through the toll (zeige TLR4 Antikörper)-like receptor pathway

  7. Data suggest that, in monocytes and macrophages, the interleukin-1B- (IL1B (zeige IL1B Antikörper))-stimulated trans-autophosphorylation of IRAK4 (interleukin-1 receptor-associated kinase 4 (zeige IRAK4 Antikörper)) is initiated by MYD88-induced dimerization of IRAK4 (zeige IRAK4 Antikörper). In contrast, IRAK1 (interleukin-1 receptor-associated kinase 1 (zeige IRAK1 Antikörper)) is inactive in unstimulated monocytes/macrophages and is converted to an active protein kinase (zeige CDK7 Antikörper) in response to IL1B (zeige IL1B Antikörper).

  8. our data suggest a new role of MyD88 in the development of glucose intolerance and hepatic steatosis.

  9. In patient population from Southeast Serbia Myd 88 L265 mutation was not responsible for the development of diffuse large B-cell non Hodgkin lymphoma.

  10. FSTL1 (zeige FSTL1 Antikörper) displays anti-inflammatory effects against oxidized low-density lipoprotein-induced pro-inflammatory cytokine production via a mechanism that involves the TLR4 (zeige TLR4 Antikörper)/MyD88/NF-kappaB (zeige NFKB1 Antikörper) and MAPK (zeige MAPK1 Antikörper) signaling pathways.

Pig (Porcine) Myeloid Differentiation Primary Response Gene (88) (MYD88) Interaktionspartner

  1. These results suggest that porcine circovirus 2 induces IL-8 (zeige IL8 Antikörper) secretion via the TLR2 (zeige TLR2 Antikörper)/MyD88/NF-kappaB (zeige NFKB1 Antikörper) signalling pathway.

  2. At 30 days after autotransplantation of a pig kidney, mRNA expression increases for MyD88.

  3. These results suggest that an MyD88-dependent signaling pathway is present in newborn as well as in adult swine and that it is involved in the innate immune system of these animals.

Cow (Bovine) Myeloid Differentiation Primary Response Gene (88) (MYD88) Interaktionspartner

  1. L. rhamnosus GR-1 ameliorates the E. coli-induced disruption of cellular ultrastructure, subsequently reducing the percentage of bovine endometrial epithelial cells apoptosis and limiting inflammatory responses, partly via attenuation of MyD88-dependent and MyD88-independent pathway activation

  2. Modulated cytokine expression in Bovine viral diarrhea virus type 2 infected macrophages was associated with decreased MyD88 expression.

  3. The study demonstrates that in cattle, animals heterozygous at the MyD88 A625C polymorphic marker have a 5-fold reduced risk for active pulmonary tuberculosis.

  4. MyD88 plays a functional role in transducing LPS (zeige IRF6 Antikörper) signaling from TLR-4 (zeige TLR4 Antikörper) to downstream effector molecules involved in NF-kappaB (zeige NFKB1 Antikörper) activation

Atlantic Salmon (Salmo salar) Myeloid Differentiation Primary Response Gene (88) (MYD88) Interaktionspartner

  1. MyD88 interacts with interferon (zeige IFNA Antikörper) regulatory factor (IRF) 3 (zeige IRF3 Antikörper) and IRF7 (zeige IRF7 Antikörper) in Atlantic salmon (Salmo salar)

  2. the salmon MyD88 was cloned and its expression was analysed.

Mouse (Murine) Myeloid Differentiation Primary Response Gene (88) (MYD88) Interaktionspartner

  1. These data show that the normal distribution of surface glycosylation requires IL-1R, but not MyD88, and is not sufficient to prevent bacterial binding.

  2. data show that in pericytes, MyD88 and IRAK4 (zeige IRAK4 Antikörper) are key regulators of 2 major injury responses: inflammatory and fibrogenic.

  3. TLR4 (zeige TLR4 Antikörper) agonist MPLA potently induced MyD88-dependent signaling. Neutrophil recruitment after multiple injections of MPLA was reliant on MyD88-dependent signaling. MPLA treatment induced expansion of myeloid progenitors in bone marrow and upregulation of CD11b (zeige ITGAM Antikörper) and shedding of L-selectin (zeige SELL Antikörper) by neutrophils, all of which were attenuated in MyD88-deficient mice.

  4. Autophagy contributes to macrophage resistance to Leishmania major. Data, including data from studies in knockout mice, suggest a key resistance mechanism involves endosomal signaling via Tlr3 (zeige TLR3 Antikörper)/7/9 in macrophages; macrophages deficient for Tlr3 (zeige TLR3 Antikörper)/7/9, Unc93b1 (zeige UNC93B1 Antikörper), or MyD88 fail to undergo L. major-induced autophagy. (TLR = Toll (zeige TLR4 Antikörper)-like receptor; Unc93b1 (zeige UNC93B1 Antikörper) = unc-93 (zeige UNC93B1 Antikörper) homolog B1; MyD88 = myeloid differentiation primary response gene 88)

  5. MyD88 inhibitor ST2825 attenuates acute cardiac rejection and promotes donor-specific hyporesponsiveness in stringent skin transplant models

  6. MyD88 has a divergent requirement for cell survival in non-Tregs and Tregs, and a yet-to-be defined survival-independent requirement for Treg function during the response to alloantigen

  7. The aim of this study was to examine the role of the common TLR adaptor protein myeloid-differentiation factor (MyD) 88 in lung epithelium during host defense against K. pneumoniae-induced pneumonia.

  8. TLR2 (zeige TLR2 Antikörper), TLR4 (zeige TLR4 Antikörper) AND MyD88 mediate allergic airway disease (AAD) and Streptococcus pneumoniae-induced suppression of AAD.

  9. miR (zeige MLXIP Antikörper)-23a-5p modulated the innate host defense by promoting mycobacteria survival and inhibiting the activation of autophagy against Mycobacterium tuberculosis through TLR2 (zeige TLR2 Antikörper)/MyD88/NF-kappaB (zeige NFKB1 Antikörper) pathway by targeting TLR2 (zeige TLR2 Antikörper).

  10. results indicate that the R753Q polymorphism alters TLR2 (zeige TLR2 Antikörper) signaling competence, leading to impaired MyD88-TLR2 (zeige TLR2 Antikörper) assembly, reduced phosphorylation of IRAK-1 (zeige IRAK1 Antikörper), diminished activation of MAPKs and NF-kappaB (zeige NFKB1 Antikörper), and deficient induction of cytokines in macrophages infected with M. smegmatis.

MYD88 Antigen-Profil

Beschreibung des Gens

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with MYD88

  • myeloid differentiation primary response 88 (MYD88) Antikörper
  • interleukin-1 receptor-associated kinase 2 (irak2) Antikörper
  • interleukin-1 receptor-associated kinase 2 (IRAK2) Antikörper
  • interleukin-1 receptor-associated kinase 2 (LOC100228175) Antikörper
  • myeloid differentiation primary response gene (88) (myd88-b) Antikörper
  • myeloid differentiation primary response gene 88 (Myd88) Antikörper
  • CG2078 gene product from transcript CG2078-RB (Myd88) Antikörper
  • myeloid differentiation primary response 88 (Myd88) Antikörper
  • myeloid differentiation primary response gene (88) (MYD88) Antikörper
  • myeloid differentiation primary response gene (88) (myd88) Antikörper
  • myeloid differentiation primary response factor 88 (Myd88) Antikörper
  • myeloid differentiation primary response 88 (myd88) Antikörper
  • MyD88 adaptor (myd88) Antikörper
  • myeloid differentiation factor 88 (myd88) Antikörper
  • myeloid differentiation response protein 88 (myd88) Antikörper
  • myeloid differentiation primary response gene 88 (myd88) Antikörper
  • CG2078 Antikörper
  • Dmel\\CG2078 Antikörper
  • DmMyd88 Antikörper
  • dMyd88 Antikörper
  • EP(2)2535 Antikörper
  • GB12344 Antikörper
  • irak-2 Antikörper
  • kra Antikörper
  • LD20892 Antikörper
  • MGC84928 Antikörper
  • myd88 Antikörper
  • myd88d Antikörper
  • Myd88F Antikörper
  • NV10640 Antikörper
  • XMyD88 Antikörper
  • zgc:103541 Antikörper

Bezeichner auf Proteinebene für MYD88

myeloid differentiation primary response gene (88) , myeloid differentiation primary response protein MyD88 , interleukin-1 receptor-associated kinase-like 2 , interleukin-1 receptor-associated kinase 2 , myeloid differentiation primary response protein MyD88-B , Toll/IL-1 receptor binding protein MyD88-B , CG2078-PA , CG2078-PB , Myd88-PA , Myd88-PB , Myd88F , krapfen , myeloid differentiation primary response gene 88 , myeloid differentiation primary response factor 88 , zMyD88 , myeloid differentiation factor 88 , myeloid differentiation primary response protein 88 , myeloid differentiation response protein 88

GENE ID SPEZIES
4615 Homo sapiens
493227 Xenopus (Silurana) tropicalis
416118 Gallus gallus
100228175 Taeniopygia guttata
734302 Xenopus laevis
17874 Mus musculus
35956 Drosophila melanogaster
301059 Rattus norvegicus
396646 Sus scrofa
403145 Danio rerio
413194 Apis mellifera
420420 Gallus gallus
444881 Bos taurus
460269 Pan troglodytes
477024 Canis lupus familiaris
549591 Xenopus (Silurana) tropicalis
678682 Ovis aries
696494 Macaca mulatta
100118553 Nasonia vitripennis
100134853 Takifugu rubripes
100136123 Oncorhynchus mykiss
100169859 Salmo salar
100305041 Ictalurus punctatus
100616081 Amphimedon queenslandica
575153 Strongylocentrotus purpuratus
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