IL1R1 Proteine (IL1R1)

Bezeichnung:
Interleukin 1 Receptor, Type I Proteine (IL1R1)
Auf www.antikoerper-online.de finden Sie aktuell 38 Interleukin 1 Receptor, Type I (IL1R1) Proteine von 7 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen IL1R1 Antikörper (218) und IL1R1 Kits (31) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 305 IL1R1 Produkte verfügbar.
Synonyme:
CD121a, CD121b, D2S1473, IL-1R-alpha, IL-iR, IL1R, Il1r-1, IL1RA, P80
alle Proteine anzeigen Gen GeneID UniProt
IL1R1 3554 P14778
IL1R1 16177 P13504
IL1R1 25663  

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Am meisten referenzierte IL1R1 Proteine

  1. Human IL1R1 Protein expressed in Human Cells - ABIN2002132 : Vigers, Anderson, Caffes, Brandhuber: Crystal structure of the type-I interleukin-1 receptor complexed with interleukin-1beta. in Nature 1997 (PubMed)
    Zeige alle 5 Referenzen für 2002132

  2. Cynomolgus IL1R1 Protein expressed in Human Cells - ABIN2010087 : Schreuder, Tardif, Trump-Kallmeyer, Soffientini, Sarubbi, Akeson, Bowlin, Yanofsky, Barrett: A new cytokine-receptor binding mode revealed by the crystal structure of the IL-1 receptor with an antagonist. in Nature 1997 (PubMed)
    Zeige alle 5 Referenzen für 2010087

  3. Cynomolgus IL1R1 Protein expressed in Human Cells - ABIN2010085 : Reddy, Huang, Liao: Phosphatidylinositol 3-kinase in interleukin 1 signaling. Physical interaction with the interleukin 1 receptor and requirement in NFkappaB and AP-1 activation. in The Journal of biological chemistry 1997 (PubMed)
    Zeige alle 5 Referenzen für 2010085

  4. Human IL1R1 Protein expressed in Human Cells - ABIN2002133 : Huang, Gao, Li, Cao: Recruitment of IRAK to the interleukin 1 receptor complex requires interleukin 1 receptor accessory protein. in Proceedings of the National Academy of Sciences of the United States of America 1998 (PubMed)
    Zeige alle 5 Referenzen für 2002133

  5. Mouse (Murine) IL1R1 Protein expressed in Human Cells - ABIN2008322 : Vigers, Dripps, Edwards, Brandhuber: X-ray crystal structure of a small antagonist peptide bound to interleukin-1 receptor type 1. in The Journal of biological chemistry 2001 (PubMed)
    Zeige alle 5 Referenzen für 2008322

Weitere Proteine zu IL1R1 Interaktionspartnern

Human Interleukin 1 Receptor, Type I (IL1R1) Interaktionspartner

  1. Since mumps virus SH coimmunoprecipitated with tumor necrosis factor receptor 1 (TNFR1 (zeige TNFRSF1A Proteine)), RIP1 (zeige UQCRFS1 Proteine), and IRAK1 (zeige IRAK1 Proteine), we hypothesize that SH exerts its NF-kappaB (zeige NFKB1 Proteine) activation inhibitory function by interacting with TNFR1 (zeige TNFRSF1A Proteine), interleukin-1 receptor type 1 (IL-1R1), and TLR3 (zeige TLR3 Proteine) complexes in the plasma membrane of infected cells.

  2. ligand-activation of GPER generates a feedforward loop coupling IL1beta induction by CAFs to IL1R1 expression by cancer cells, promoting the up-regulation of IL1beta/IL1R1 target genes such as PTGES, COX2, RAGE and ABCG2

  3. this study shows that IL-1a (zeige IL1A Proteine) gene variants are not associated with susceptibility to juvenile idiopathic arthritis in Iranian population

  4. The work identifies a pathogenic role of postnatal IL1b (zeige IL1B Proteine)/IL-1R1 pathway and subsequent prolonged prominent increase of endocannabinoid signaling in adult seizure susceptibility following prolonged febrile seizures, and highlights IL-1R1 as a potential therapeutic target for preventing the development of epilepsy after infantile febrile seizures.

  5. The results present identification of critical regions within the TIR domain of IL-1 (zeige IL1A Proteine) receptor type in humans and mice.

  6. IL1R1 (zeige IL1RN Proteine) SNP rs949963 is associated with the susceptibility to asthma in children from Central China and may increase the serum expression of IL1R1 (zeige IL1RN Proteine).

  7. Altered expression of EP2 (zeige SPAG11B Proteine) in patients with aspirin-exacerbated respiratory disease contributes to deficient induction of IL-1RI, reducing the capacity of IL-1beta (zeige IL1B Proteine) to increase COX-2 and mPGES-1 (zeige PTGES Proteine) expression, which results in low PGE2 production

  8. investigated the association between four inflammatory cytokines (CD121a, interleukin [IL]-1beta, IL-8 (zeige IL8 Proteine), and IL-11 (zeige IL11 Proteine)) and coronary heart disease

  9. This study found that the mRNA expression of IL-1R1, TNFR1 (zeige TNFRSF1A Proteine), and TNFR2 (zeige TNFRSF1B Proteine) was significantly higher in schizophreina

  10. IL-1R1 expression appears to define a tissue regulatory T cell phenotype together with the expression of CD25 (zeige IL2RA Proteine), glucocorticoid-induced tumor necrosis factor (zeige TNF Proteine) receptor family-related gene and CTLA-4 (zeige CTLA4 Proteine).

Mouse (Murine) Interleukin 1 Receptor, Type I (IL1R1) Interaktionspartner

  1. Results demonstrated the essential role of IL-1R1 in kindling-induced sleep disturbance by using transgenic IL-1R1 KO mice. Epilepsy-induced sleep disturbances were absent in the IL-1R1 KO mice, indicating the importance of IL-1 (zeige IL1A Proteine) signals. The knockout of IL-1R1 did not change the seizure thresholds, suggesting that IL-1R1 signaling is not in involved in the kindling-induced epileptogenesis.

  2. findings show elements of the IL-1 (zeige IL1A Proteine) network, including IL-1alpha, IL-1beta (zeige IL1B Proteine), and IL-1R1, are essential for the optimal host response to VACV cutaneous infection

  3. These data show that the normal distribution of surface glycosylation requires IL-1R, but not MyD88 (zeige MYD88 Proteine), and is not sufficient to prevent bacterial binding.

  4. IL-1R1 signaling via MyD88 (zeige MYD88 Proteine) is critical for the first step of inflammatory response to papain.

  5. The work identifies a pathogenic role of postnatal IL1b (zeige IL1B Proteine)/IL-1R1 pathway and subsequent prolonged prominent increase of endocannabinoid signaling in adult seizure susceptibility following prolonged febrile seizures.

  6. SER140 treatment postpones the onset of diabetes in female NOD mice by interfering with IL-1beta (zeige IL1B Proteine)/Il1 (zeige IL1A Proteine) receptor signaling.

  7. IL-1 (zeige IL1A Proteine) receptor (IL-1R1) deficiency or blockade limits blood pressure elevation in this model by mitigating sodium reabsorption via the NKCC2 (zeige SLC12A1 Proteine) co-transporter in the nephron.

  8. data identify a previously unappreciated Trim24 (zeige TRIM24 Proteine)-dependent requirement for IL-1R expression on TH2 cells and an important nonredundant role for T-cell-intrinsic Trim24 (zeige TRIM24 Proteine) in TH2-mediated allergy and antihelminth immunity

  9. The results present identification of critical regions within the TIR domain of IL-1 (zeige IL1A Proteine) receptor type in humans and mice.

  10. IL-1R1/MyD88 (zeige MYD88 Proteine) signaling negatively regulates bone regeneration via impairment of mesenchymal stem cell proliferation, migration and differentiation by inhibiting the Akt (zeige AKT1 Proteine)/GSK-3beta/beta-catenin (zeige CTNNB1 Proteine) pathway.

IL1R1 Protein Überblick

Protein Überblick

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. This gene along with interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1 receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.

Alternative names and synonyms associated with IL1R1

  • interleukin 1 receptor, type I (IL1R1)
  • interleukin 1 receptor, type I (Il1r1)
  • CD121a Protein
  • CD121b Protein
  • D2S1473 Protein
  • IL-1R-alpha Protein
  • IL-iR Protein
  • IL1R Protein
  • Il1r-1 Protein
  • IL1RA Protein
  • P80 Protein

Bezeichner auf Proteinebene für IL1R1

CD121 antigen-like family member A , IL-1R-1 , IL-1RT-1 , IL-1RT1 , antigen CD121a , interleukin 1 receptor alpha, type I , interleukin receptor 1 , interleukin-1 receptor alpha , interleukin-1 receptor type 1 , interleukin-1 receptor type I , IL-1 receptor alpha chain , IL-1R-alpha , p80 , interleukin 1 beta receptor type 1 short transmembrane form , interleukin 1 beta receptor type 1 soluble form , interleukin 1 bete receptor type 1 long transmembrane form

GENE ID SPEZIES
3554 Homo sapiens
16177 Mus musculus
25663 Rattus norvegicus
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