Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Weitere Synonyme anzeigen
Wählen Sie die gewünschte Spezies
Human ARHGDIA Protein expressed in Escherichia coli (E. coli) - ABIN667259
DerMardirossian, Rocklin, Seo, Bokoch: Phosphorylation of RhoGDI by Src regulates Rho GTPase binding and cytosol-membrane cycling. in Molecular biology of the cell 2006
Zeige alle 2 Referenzen für ABIN667259
Increased expression of bovine Rho GDIalpha (zeige GDI1 Proteine) led to electrophysiological alterations that resulted in atrial arrhythmias and AV conduction abnormalities in transgenic mice, whereas ventricular contractile function was largely preserved.
that inhibition of Ca2 (zeige CA2 Proteine)+ channel activity by overexpression of Rho GDI-alpha is mediated by inhibition of RhoA (zeige RHOA Proteine) in cardiac myocytes
Rho GDP association inhibitor (GDI) alpha- mediated disruption of Rho GTPase (zeige RACGAP1 Proteine) activity impairs lens fiber cell migration, elongation and survival.
Together, our results suggest a role for Ly-GDI (zeige ARHGDIB Proteine) in the localized regulation of Rho GTPases in platelets and hypothesize a link between the PKC (zeige PRRT2 Proteine) and Rho GTPase (zeige RACGAP1 Proteine) signaling systems in platelet function.
MiR (zeige MLXIP Proteine)-25 is activated by the WNT (zeige WNT2 Proteine)/beta-catenin (zeige CTNNB1 Proteine) signaling pathway, and exerts its pro-metastatic function by directly inhibiting the Rho GDP dissociation inhibitor alpha (RhoGDI1). Downregulation of RhoGDI1 enhances expression of Snail (zeige SNAI1 Proteine), thereby promoting EMT (zeige ITK Proteine).
RIP2 and RhoGDI bind to p75(NTR (zeige NGFR Proteine)) death domain at partially overlapping epitopes with over 100-fold difference in affinity, revealing the mechanism by which RIP2 recruitment displaces RhoGDI upon ligand binding.
Downregulation of RhoGDI could be a critical mechanism of breast tumor development, which may involve the hyperactivation of Rho GTPases and upregulation of COX-2 activity.
RHOGDI alpha acetylation interferes with Rho signaling, resulting in alteration of cellular filamentous actin.
the present study has identified loss of ARHGDIA contributed to the processes of hepatic tumorigenesis, in particular invasion and metastasis
new mechanistic insights into the understanding of essential role of SUMOylation at Lys (zeige LYZ Proteine)-138 in RhoGDIalpha's biological function.
By directly targeting the Rho GDP dissociation inhibitor alpha (RhoGDI1) and activated leukocyte cell adhesion molecule (ALCAM (zeige ALCAM Proteine)).
A significant trend was identified between loss of RhoGDI expression in hepatocellular carcinoma and worsening clinical prognosis.
Our findings suggest that RhoGDI overexpression is a predictor of distant metastasis and plays an important role in the progression of hepatocellular carcinoma
Integrin beta 8 and PTP-PEST (zeige PTPN12 Proteine) form protein complexes at the leading edge of migrating cells and balance patterns of Rac1 and Cdc42 (zeige CDC42 Proteine) signaling by controlling the subcellular localization and phosphorylation status of Rho GDP dissociation inhibitor 1.
RhoGDalpha controls ENaC expression and activity via Rac1.
the association of RhoGDIalpha with TROY (zeige TNFRSF19 Proteine) contributed to TROY (zeige TNFRSF19 Proteine)-dependent RhoA (zeige RHOA Proteine) activation and neurite outgrowth inhibition after Nogo (zeige RTN4 Proteine)-66 stimulation.
Data found that CCK (zeige CCK Proteine)-induced PKCalpha (zeige PKCa Proteine) phosphorylation on RhoGDI1 at Ser96 releases RhoA (zeige RHOA Proteine) and Rac1 from RhoGDI1 to facilitate Rho GTPases signaling.
we demonstrated the regulation of targeting/accumulation of the RhoGDIalpha-Rac1 complex to phagosomes
how the beta cell utilizes RhoGDI for differential Cdc42 and Rac1 cycling
Inhibition of Rho family GTPases by Rho GDP dissociation inhibitor disrupts cardiac morphogenesis and inhibits cardiomyocyte proliferation.
analysis of inhibitory and shuttling functions of rhoGDI-3 (zeige ARHGDIG Proteine) and rhoGDI-1
isoprenylcysteine carboxylmethyltransferase (zeige ICMT Proteine) regulates Rac1 activity by controlling the interaction of Rac1 with RhoGDI through TNFA (zeige TNF Proteine)
Aplysia Ras-related homologs (ARHs), also called Rho genes, belong to the RAS gene superfamily encoding small guanine nucleotide exchange (GTP/GDP) factors. The ARH proteins may be kept in the inactive, GDP-bound state by interaction with GDP dissociation inhibitors, such as ARHGDIA (Leffers et al., 1993
rho GDP-dissociation inhibitor 1
, Rho GDP dissociation inhibitor (GDI) alpha
, rho GDI 1
, rho-GDI alpha
, Rho GDI alpha