anti-Pferd Reticulon 4 Antikörper für Western Blotting

Recommended Reticulon 4 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Reticulon 4 (RTN4) Antikörper
  • ASY
  • NI220/250
  • NOGO
  • NOGO-A
  • NOGOC
  • NSP
  • NSP-CL
  • Nbla00271
  • Nbla10545
  • Nogo-B
  • Nogo-C
  • RTN-X
  • RTN4-A
  • RTN4-B1
  • RTN4-B2
  • RTN4-C
  • RTN4-Cw
  • DKFZp459C0314
  • 1110020G17Rik
  • AA407876
  • AA409940
  • AA960376
  • C130026I10Rik
  • NgA
  • Nogo-A
  • mKIAA0886
  • mKIAA4153
  • NI-250
  • Nogo
  • Vp20
  • r
  • rat N
  • rat NogoA
  • reticulon-4
  • nogo
  • rtn4
  • wu:fb17a02
  • wu:fb22f12
  • wu:fd61a07
  • zgc:92163
  • reticulon 4
  • reticulon 4a
  • RTN4
  • rtn4
  • Rtn4
  • rtn4a
Epitop
Middle Region
16
16
15
12
10
5
5
4
4
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus), Schaf, Zebrafisch
129
109
109
10
7
7
7
7
4
4
3
3
1
1
Wirt
Kaninchen
135
10
5
3
2
Klonalität
Polyklonal
Konjugat
Unkonjugiert
6
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
Applikation
Western Blotting (WB)
114
54
50
44
26
11
9
9
4
2
2
Optionen
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Bilder

Produktnummer ABIN2782749
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.0855882 ABIN2782750 WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 1
1 ABIN321157 WB Rabbit IgG AA 81-130 Anmelden zum Anzeigen Polyclonal
1 ABIN321156 WB Rabbit IgG AA 254-303 Anmelden zum Anzeigen Polyclonal
1 ABIN2627778 IHC (p) WB Rabbit IgG AA 1170-1192 Anmelden zum Anzeigen Polyclonal

General

Antigen Reticulon 4 (RTN4) Antikörper
Epitop Middle Region
(16), (16), (15), (12), (10), (5), (5), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus), Schaf, Zebrafisch
(129), (109), (109), (10), (7), (7), (7), (7), (4), (4), (3), (3), (1), (1)
Wirt Kaninchen
(135), (10), (5), (3), (2)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(6), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Applikation Western Blotting (WB)
(114), (54), (50), (44), (26), (11), (9), (9), (4), (2), (2)
Pubmed 2 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN983311.
Sequenz FRIYKGVIQA IQKSDEGHPF RAYLESEVAI SEELVQKYSN SALGHVNCTI
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 79%
Produktmerkmale This is a rabbit polyclonal antibody against RTN4. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human RTN4

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung RTN4 (RTN4 Antibody Abstract)
Hintergrund RTN4 belongs to the family of reticulons. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. RTN4 is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates.This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified.This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified.
Alias Symbols: ASY, NI220/250, NOGO, NOGO-A, NOGOC, NSP, NSP-CL, Nbla00271, Nbla10545, Nogo-B, Nogo-C, RTN-X, RTN4-A, RTN4-B1, RTN4-B2, RTN4-C
Protein Interaction Partner: HUWE1, SYT16, ZFYVE21, RTN4, SNX15, ARL6IP1, SNX1, UBC, RPA3, RPA2, RPA1, vpu, BAIAP2, LAMA4, ATF2, CLN8, TMEM65, S100A16, EPPK1, SNX12, ACAA2, SLC9A3R2, TJP1, HNRNPM, ILF3, IGFBP7, DDB1, SLC25A10, CIRBP, TERF1, POT1, RPS27, NR4A1, HLA-DPB1, RTN3, RTN4IP1
Protein Size: 392
Molekulargewicht 42 kDa
Gen-ID 57142
NCBI Accession NM_207520, NP_997403
UniProt Q9NQC3
Pathways Neurotrophin Signalübertragung, Regulation of Cell Size

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 392 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Referenzen Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Beetz, Koch, Khundadze, Zimmer, Nietzsche, Hertel, Huebner, Mumtaz, Schweizer, Dirren, Karle, Irintchev, Alvarez, Redies, Westermann, Kurth, Deufel, Kessels, Qualmann, Hübner: "A spastic paraplegia mouse model reveals REEP1-dependent ER shaping." in: The Journal of clinical investigation, Vol. 123, Issue 10, pp. 4273-82, 2013

Allgemeine Veröffentlichungen

Hu, Strittmatter: "The N-terminal domain of Nogo-A inhibits cell adhesion and axonal outgrowth by an integrin-specific mechanism." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 28, Issue 5, pp. 1262-9, 2008

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Reticulon 4 (RTN4) (Middle Region) antibody (ABIN2782749) anti-Reticulon 4 (RTN4) (Middle Region) antibody