Arhgef9 (Arhgef9) ELISA Kits

Bezeichnung:
Cdc42 Guanine Nucleotide Exchange Factor (GEF) 9 ELISA Kits (Arhgef9)
Auf www.antikoerper-online.de finden Sie aktuell 0 Cdc42 Guanine Nucleotide Exchange Factor (GEF) 9 (Arhgef9) ELISA Kits von unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Arhgef9 Antikörper (55) und Arhgef9 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 65 Arhgef9 Produkte verfügbar.
Synonyme:
9630036L12Rik, A230067K14, ARHGEF9, COLLYBISTIN, EIEE8, HPEM-2, mKIAA0424, PEM-2, PEM2, wu:fj33b10
list all ELISA KIts Gen GeneID UniProt
Human Arhgef9 Arhgef9 23229 O43307
Ratte Arhgef9 Arhgef9 66013 Q9QX73
Maus Arhgef9 Arhgef9 236915 Q3UTH8

Weitere Synonyme anzeigen

Weitere ELISA Kits für Arhgef9 Interaktionspartner

Human Cdc42 Guanine Nucleotide Exchange Factor (GEF) 9 (Arhgef9) Interaktionspartner

  1. Autism spectrum disorder patient with the smallest inactivating deletion in the collybistin gene.

  2. Collybistin forms a complex with mTOR (zeige FRAP1 ELISA Kits) and eIF3 (zeige EIF3A ELISA Kits) and by sequestering these proteins downregulates mTORC1 signaling and protein synthesis potentially contributing to intellectual disability and autism.

  3. Impairment of the membrane lipid binding activity of Collybistin R290H and a consequent defect in inhibitory synapse maturation represent a likely molecular pathomechanism of epilepsy and mental retardation in humans.

  4. The enhancement of Cb-induced gephyrin (zeige GPHN ELISA Kits) clustering by GTP (zeige AK3 ELISA Kits)-TC10 (zeige RHOQ ELISA Kits) does not depend on the guanine nucleotide exchange activity of Cb but involves an interaction that resembles reported interactions of other small GTPases with their effectors

  5. Phosphorylation of gephyrin (zeige GPHN ELISA Kits) in hippocampal neurons by cyclin-dependent kinase (zeige CDK1 ELISA Kits) CDK5 (zeige CDK5 ELISA Kits) at Ser (zeige SIGLEC1 ELISA Kits)-270 is dependent on collybistin.

  6. Data indicate that ARHGEF9 is likely to be responsible for syndromic X-linked mental retardation associated with epilepsy.

  7. These results reveal that G(s) and G(q) signalings regulate hPEM-2 functions through PKA and c-Src (zeige SRC ELISA Kits) in Neuro-2a neuroblastoma (zeige ARHGEF16 ELISA Kits) cells, respectively.

  8. major regulator of GABAergic postsynaptic gephyrin (zeige GPHN ELISA Kits) clustering

  9. Study propose that the collybistin-gephyrin (zeige GPHN ELISA Kits) complex has an intimate role in the clustering of GABA(A)Rs containing the alpha2 subunit.

  10. Here we identified residues critical for interaction with gephyrin (zeige GPHN ELISA Kits) in the linker region between the SH3 and the DH domains of collybistin.

Mouse (Murine) Cdc42 Guanine Nucleotide Exchange Factor (GEF) 9 (Arhgef9) Interaktionspartner

  1. Within this network, collybistin can adopt open/active and closed/inactive conformations to act as a switchable adaptor that links gephyrin (zeige GPHN ELISA Kits) to plasma membrane phosphoinositides.

  2. data show that collybistin co-clusters with gephyrin (zeige GPHN ELISA Kits) and GABA(A) Rs in synaptic puncta and is recruited to postsynaptic specializations early during synapse development; it co-localizes with GABA(A) Rs containing the alpha1, alpha2, or alpha3 subunits

  3. The results of this study provided evidence that the formation of gephyrin (zeige GPHN ELISA Kits) scaffolds at inhibitory synapses requires an intact Cb II PH-domain but is Cdc42 (zeige CDC42 ELISA Kits)-independent.

  4. The resolution crystal structure of the Cdc42 (zeige CDC42 ELISA Kits)-collybistin II complex reveals a novel conformation of the switch I region of Cdc42 (zeige CDC42 ELISA Kits), and biochemical data indicate that gephyrin (zeige GPHN ELISA Kits) negatively regulates collybistin activity.

  5. Cb is essential for gephyrin (zeige GPHN ELISA Kits)-dependent clustering of a specific set of GABA(A) receptors, but not required for glycine receptor (zeige GLRB ELISA Kits) postsynaptic localization.

  6. Data provide the first evidence that collybistin deficiency leads to significant changes of GABAergic inhibition, network excitability and synaptic plasticity in vivo.

Arhgef9 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes. Defects in this gene are a cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy. Three transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Arhgef9

  • Cdc42 guanine nucleotide exchange factor (GEF) 9 (ARHGEF9) Elisa Kit
  • Cdc42 guanine nucleotide exchange factor (GEF) 9b (arhgef9b) Elisa Kit
  • Cdc42 guanine nucleotide exchange factor (GEF) 9 (arhgef9) Elisa Kit
  • Cdc42 guanine nucleotide exchange factor (GEF) 9 (Arhgef9) Elisa Kit
  • CDC42 guanine nucleotide exchange factor (GEF) 9 (Arhgef9) Elisa Kit
  • rho guanine nucleotide exchange factor 9-like (LOC537718) Elisa Kit
  • 9630036L12Rik Elisa Kit
  • A230067K14 Elisa Kit
  • ARHGEF9 Elisa Kit
  • COLLYBISTIN Elisa Kit
  • EIEE8 Elisa Kit
  • HPEM-2 Elisa Kit
  • mKIAA0424 Elisa Kit
  • PEM-2 Elisa Kit
  • PEM2 Elisa Kit
  • wu:fj33b10 Elisa Kit

Bezeichner auf Proteinebene für Arhgef9

Cdc42 guanine nucleotide exchange factor (GEF) 9 , Cdc42 guanine nucleotide exchange factor 9 , Cdc42 guanine exchange factor 9 , rho guanine nucleotide exchange factor 9-like , PEM-2 homolog , hPEM-2 collybistin , rac/Cdc42 guanine nucleotide exchange factor 9 , rho guanine nucleotide exchange factor 9 , collybistin I , collybistin

GENE ID SPEZIES
422315 Gallus gallus
465666 Pan troglodytes
560923 Danio rerio
100018406 Monodelphis domestica
100054217 Equus caballus
100125033 Xenopus (Silurana) tropicalis
100338091 Oryctolagus cuniculus
100393157 Callithrix jacchus
100512575 Sus scrofa
100586595 Nomascus leucogenys
23229 Homo sapiens
66013 Rattus norvegicus
236915 Mus musculus
100171927 Pongo abelii
537718 Bos taurus
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