rho Guanine Nucleotide Exchange Factor (GEF) 4 Proteine (ARHGEF4)

Bezeichnung:
rho Guanine Nucleotide Exchange Factor (GEF) 4 Proteine (ARHGEF4)
Auf www.antikoerper-online.de finden Sie aktuell 4 rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) Proteine von 2 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen rho Guanine Nucleotide Exchange Factor (GEF) 4 Antikörper (47) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 55 rho Guanine Nucleotide Exchange Factor (GEF) 4 Produkte verfügbar.
Synonyme:
9330140K16Rik, ARHGEF4, Asef, ASEF1, ENSMUSG00000070955, GEF4, STM6
alle Proteine anzeigen Gen GeneID UniProt
ARHGEF4 50649 Q9NR80
ARHGEF4 226970 Q7TNR9
Ratte ARHGEF4 ARHGEF4 301334  

Weitere Synonyme anzeigen

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Weitere Proteine zu rho Guanine Nucleotide Exchange Factor (GEF) 4 Interaktionspartnern

Human rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) Interaktionspartner

  1. Although inappropriate promoter methylation was not invariantly associated with reduced transcript expression, a significant association was apparent for the ARHGEF4, PON3 (zeige PON3 Proteine), STAT5a (zeige STAT5A Proteine), and VAX2 (zeige VAX2 Proteine) gene transcripts (P<0.05). Herein, we present the first genome-wide DNA methylation (zeige HELLS Proteine) analysis in a unique HG-NMIBC cohort, showing extensive and discrete methylation changes relative to normal bladder and low-intermediate-grade tumor

  2. These data demonstrate, that in addition to microtubule-independent Tiam1 (zeige TIAM1 Proteine) activation, HGF (zeige HGF Proteine) engages additional microtubule- and APC (zeige APC Proteine)-dependent pathway of Asef activation.

  3. these results demonstrate potent anti-inflammatory effects by HGF (zeige HGF Proteine) and delineate a key role of Asef in the mediation of the HGF (zeige HGF Proteine) barrier protective and anti-inflammatory effects.

  4. Expression of Asef was associated with lower estimated glomerular filtration rate in kidney disease.

  5. Expression of ARHGEF4 (Rho guanine nucleotide exchange factor 4) is restricted to the brain and may regulate the actin cytoskeletal network, cell morphology and migration, and neuronal function

  6. structures thus elucidate the molecular mechanism of Asef recognition by APC (zeige APC Proteine)

  7. Forced expression of Asef in vitro induced and maintained proliferation of haemaopoietic progenitor cells and co-operated with TEL-AML1 greatly to enhance proliferation and haemopoietic colony size

  8. Positive role of Tyr94 phosphorylation in EGF-induced Asef activation following the activation of Rac1.

  9. Asef and APC (zeige APC Proteine) function downstream of HGF (zeige HGF Proteine) and PI3-kinase (zeige PIK3CA Proteine), and play critical roles in growth factor-mediated regulation of cell morphology and migration

Mouse (Murine) rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) Interaktionspartner

  1. Asef has a role in HGF (zeige HGF Proteine)-mediated protection against endothelial hyperpermeability and lung injury.

  2. these results demonstrate potent anti-inflammatory effects by HGF (zeige HGF Proteine) and delineate a key role of Asef in the mediation of the HGF (zeige HGF Proteine) barrier protective and anti-inflammatory effects.

  3. Asef and Asef2 (zeige SPATA13 Proteine) are required for adenoma formation in Apc (zeige APC Proteine)(Min/+)mice.

rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) Protein Überblick

Protein Überblick

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. This protein is similar to rat collybistin protein. Alternative splicing of this gene generates two transcript variants which encode different isoforms. Also there is possibility for the usage of multiple polyadenylation sites for this gene.

Alternative names and synonyms associated with rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4)

  • Rho guanine nucleotide exchange factor (GEF) 4 (ARHGEF4)
  • Rho guanine nucleotide exchange factor 4 (arhg4)
  • Rho guanine nucleotide exchange factor (GEF) 4 (Arhgef4)
  • 9330140K16Rik Protein
  • ARHGEF4 Protein
  • Asef Protein
  • ASEF1 Protein
  • ENSMUSG00000070955 Protein
  • GEF4 Protein
  • STM6 Protein

Bezeichner auf Proteinebene für ARHGEF4

Rho guanine nucleotide exchange factor (GEF) 4 , Rho guanine nucleotide exchange factor 4 , rho guanine nucleotide exchange factor 4 , rho guanine nucleotide exchange factor 4-like , APC-stimulated guanine nucleotide exchange factor 1 , APC-stimulated guanine nucleotide exchange factor

GENE ID SPEZIES
424761 Gallus gallus
470538 Pan troglodytes
483856 Canis lupus familiaris
505852 Bos taurus
100067370 Equus caballus
100380335 Salmo salar
100392066 Callithrix jacchus
100432711 Pongo abelii
100470646 Ailuropoda melanoleuca
100544917 Meleagris gallopavo
50649 Homo sapiens
226970 Mus musculus
301334 Rattus norvegicus
Ausgewählte Anbieter für rho Guanine Nucleotide Exchange Factor (GEF) 4 Proteine (ARHGEF4)
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