anti-ARHGEF12 (ARHGEF12) Antikörper

Bezeichnung:
anti-rho Guanine Nucleotide Exchange Factor (GEF) 12 Antikörper (ARHGEF12)
Auf www.antikoerper-online.de finden Sie aktuell 33 rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12) Antikörper von 10 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen ARHGEF12 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 37 ARHGEF12 Produkte verfügbar.
Synonyme:
2310014B11Rik, ARHGEF12, AU019857, LARG, mKIAA0382, PRO2792
Alle Antikörper anzeigen Gen GeneID UniProt
ARHGEF12 23365 Q9NZN5
ARHGEF12 69632  
ARHGEF12 367072  

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Meistgesuchte Reaktivitäten zu anti-ARHGEF12 (ARHGEF12) Antikörper

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anti-Human ARHGEF12 Antikörper:

anti-Mouse (Murine) ARHGEF12 Antikörper:

anti-Rat (Rattus) ARHGEF12 Antikörper:

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Weitere Antikörper gegen ARHGEF12 Interaktionspartner

Xenopus laevis rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12) Interaktionspartner

Human rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12) Interaktionspartner

  1. that leukemia-associated Rho guanine-nucleotide exchange factor can be directly phosphorylated by cyclin-dependent kinase 1 (zeige CDK1 Antikörper)

  2. Two related guanine nucleotide exchange factors (GEFs), PDZ-RhoGEF (zeige ARHGEF11 Antikörper) and leukemia-associated RhoGEF (LARG), use their PDZ (zeige INADL Antikörper) domains to bind class B plexins and play critical roles in signaling.

  3. this study identified a novel association between IOP and ARHGEF12.

  4. TGF-beta (zeige TGFB1 Antikörper) regulates LARG and GEF-H1 (zeige ARHGEF2 Antikörper) during epithelial-mesenchymal transition to affect stiffening response to force and cell invasion.

  5. LARG is a novel and temporally distinct Rho Guanine Nucleotide Exchange Factor (zeige ARHGEF28 Antikörper) required for completion of abscission.

  6. Data indicate that ICAM-1 (zeige ICAM1 Antikörper) signaling activates leukemia-associated Rho guanine nucleotide exchange factor (LARG), also known as Rho GEF (zeige SLC2A4RG Antikörper) 12 (ARHGEF12).

  7. Agonist-induced Ca2 (zeige CA2 Antikörper)+ sensitization in smooth muscle: redundancy of Rho guanine nucleotide exchange factors (RhoGEFs) and response kinetics, a caged compound study.

  8. RhoGEF (zeige ARHGEF11 Antikörper) activity of p210 (zeige EVPL Antikörper) BCR/ABL (zeige ABL1 Antikörper) directly contributes to transforming activity, and may account for the difference in disease outcome associated with p190 (zeige CNTNAP1 Antikörper) BCR/ABL (zeige ABL1 Antikörper) and p210 (zeige EVPL Antikörper) BCR/ABL (zeige ABL1 Antikörper).

  9. NIS (zeige SLC5A5 Antikörper) enhanced cell migration and invasion by binding to leukemia-associated RhoA (zeige RHOA Antikörper) guanine exchange factor

  10. The PDZ domain (zeige INADL Antikörper) of LARG is required HRH1 (zeige DHX8 Antikörper)-mediated activation of the strictly Rho-dependent transcriptional activity of serum response factor and can be mimicked by activated Galpha(q (zeige GNAQ Antikörper))(Q209L).

Mouse (Murine) rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12) Interaktionspartner

  1. LARG may play a housekeeper role in regulating constitutive RhoA (zeige RHOA Antikörper) activity. Its role in regulating platelet function may principally be through RhoA (zeige RHOA Antikörper)-independent pathways.

  2. The increase in LARG expression was accompanied by a significant increase in ACh (zeige FGFR3 Antikörper)-stimulated Rho kinase (zeige ROCK2 Antikörper) and ZIP kinase (zeige DAPK3 Antikörper) activities, and sustained muscle contraction

  3. Agonist-induced Ca2 (zeige CA2 Antikörper)+ sensitization in smooth muscle: redundancy of Rho guanine nucleotide exchange factors (RhoGEFs) and response kinetics, a caged compound study.

  4. PDZ-RhoGEF and LARG are essential for embryonic development and provide a link between thrombin and LPA receptors and Rho activation.

  5. LARG is activated by the Src family tyrosine kinase Fyn, whereas GEF-H1 catalytic activity is enhanced by ERK downstream of a signalling cascade that includes FAK and Ras

  6. new insight into the mechanism by which p115RhoGEF (zeige ARHGEF1 Antikörper) is activated by Galpha (zeige SUCLG1 Antikörper)(13).

  7. S1PR2 (zeige S1PR2 Antikörper)-dependent activation of RhoA (zeige RHOA Antikörper) in smooth muscle cells is mediated by LARG and that this signaling mechanism promotes the differentiated SMC (zeige DYM Antikörper) phenotype.

  8. Leukemia-associated Rho guanine nucleotide exchange factor promotes G alpha q (zeige GNAQ Antikörper)-coupled activation of RhoA (zeige RHOA Antikörper) (larg protein)

  9. We demonstrate colocalization of the LARG protein with the IGF-1 (zeige IGF1 Antikörper) receptor, suggesting a potential physiologic role for LARG as an activator of RhoA (zeige RHOA Antikörper) in response to IGF-1 (zeige IGF1 Antikörper).

  10. mLARG is highly expressed in hematopoietic stem cell fractions, as well as in immature erythroid cells, and provide further support to the hypothesis of the potential involvement of LARG in regulation of early stages of hematopoiesis.

Cow (Bovine) rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12) Interaktionspartner

  1. cDNA of LARG (leukemia-associated guanine nucleotide exchange factor) was identified, and its gene expression was observed to be downregulated under clinorotation, which subsequently resulted in the repression of RhoA (zeige RHOA Antikörper) activation

ARHGEF12 Antigen-Profil

Beschreibung des Gens

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with ARHGEF12

  • Rho guanine nucleotide exchange factor (GEF) 12 (arhgef12) Antikörper
  • Rho guanine nucleotide exchange factor (GEF) 12 (ARHGEF12) Antikörper
  • Rho guanine nucleotide exchange factor (GEF) 12 (Arhgef12) Antikörper
  • 2310014B11Rik Antikörper
  • ARHGEF12 Antikörper
  • AU019857 Antikörper
  • LARG Antikörper
  • mKIAA0382 Antikörper
  • PRO2792 Antikörper

Bezeichner auf Proteinebene für ARHGEF12

guanine nucleotide exchange factor , Rho guanine nucleotide exchange factor (GEF) 12 , rho guanine nucleotide exchange factor 12-like , leukemia-associated RhoGEF , leukemia-associated rho guanine nucleotide exchange factor , rho guanine nucleotide exchange factor 12 , leukemia-associated Rho guanine-nucleotide exchange factor , leukemia-associated Rho guanine nucleotide exchange factor

GENE ID SPEZIES
398710 Xenopus laevis
419752 Gallus gallus
451618 Pan troglodytes
479409 Canis lupus familiaris
712096 Macaca mulatta
779951 Xenopus (Silurana) tropicalis
100030904 Monodelphis domestica
100457621 Pongo abelii
100471078 Ailuropoda melanoleuca
100523324 Sus scrofa
100548723 Meleagris gallopavo
100602658 Nomascus leucogenys
23365 Homo sapiens
69632 Mus musculus
367072 Rattus norvegicus
503575 Bos taurus
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