Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I Proteine (ADCYAP1R1)

Bezeichnung:
Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I Proteine (ADCYAP1R1)
Auf www.antikoerper-online.de finden Sie aktuell 6 Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I (ADCYAP1R1) Proteine von 3 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I Antikörper (39) und Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I Kits (8) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 57 Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I Produkte verfügbar.
Synonyme:
2900024I10Rik, ADCYAP1R1, adcyap1r1-A, AI846590, pac1, PAC1-R, PAC1R, PACAP-R1, PACAP-R1A, PACAP1-R, pacapr, PACAPR1, PACAPR1A, pacapri
alle Proteine anzeigen Gen GeneID UniProt
ADCYAP1R1 117 P41586
ADCYAP1R1 11517 P70205
Ratte ADCYAP1R1 ADCYAP1R1 24167 P32215

Weitere Synonyme anzeigen

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Am meisten referenzierte Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I Proteine

  1. Human ADCYAP1R1 Protein expressed in Human Cells - ABIN2005574 : Jiang, Boulay, Spicher, Peyton, Brabet, Birnbaumer, Rudolph: Inactivation of the G alpha i2 and G alpha o genes by homologous recombination. in Receptors & channels 1998 (PubMed)

Weitere Proteine zu Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I Interaktionspartnern

Zebrafish Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I (ADCYAP1R1) Interaktionspartner

  1. These results suggest that, in fish, PACAP (zeige VIPR2 Proteine) and PAC1-R may play a role in brain development.

Human Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I (ADCYAP1R1) Interaktionspartner

  1. Data suggest that GCGR (glucagon receptor (zeige GCGR Proteine)) activation proceeds via a mechanism in which transmembrane helix 6 (TM6) is held in an inactive conformation by a conserved polar core and a hydrophobic lock (involving intracellular loop 3, IC3); mutations in the corresponding polar core of GCGR (zeige GCGR Proteine) or PAC1R disrupt these inhibitory elements, allow TM6 to swing outward, and induce constitutive G protein signaling.

  2. Results confirmed for the first time that doxycycline specially targeted pituitary adenylate cyclase-activating polypeptide (PACAP (zeige ADCYAP1 Proteine)) receptor type 1 (PAC1) imitating PACAP (zeige ADCYAP1 Proteine)(30-37) and acted as an enhancer by facilitating the subsequent ligand binding and the activation of PAC1.

  3. Data show that glucocorticoid response genes NR3C1 (zeige NR3C1 Proteine), ADCYAP1R1 and HSD11B2 (zeige HSD11B2 Proteine) were relatively hypomethylated whereas FKBP5 (zeige FKBP5 Proteine) was hypermethylated.

  4. High child stress and an ADCYAP1R1 single-nucleotide polymorphism are associated with reduced bronchodilator response in children with asthma.

  5. and its receptor (PAC1) are involved in stress response and anxiety.

  6. PAC1/PACAP (zeige ADCYAP1 Proteine) receptor endocytosis contributes to ERK (zeige EPHB2 Proteine) acktivation.

  7. Individual differences in ADCYAP1R1 genotype may contribute to dysregulated fear circuitry known to play a central role in posttraumatic stress disorder and other anxiety disorders.

  8. Data indicate that VIP (zeige Vip Proteine) and PACAP (zeige ADCYAP1 Proteine) increased macrophage resistance to HIV-1 replication by inducing the synthesis of beta-chemokines CCL3 (zeige CCL3 Proteine) and CCL5 (zeige CCL5 Proteine) and IL-10 (zeige IL10 Proteine) following preferential activation of the receptors VPAC2 (zeige VIPR2 Proteine) and PAC1.

  9. The findings suggest that the PACAP (zeige ADCYAP1 Proteine)-PAC1 receptor pathway may play an important role in female human responses to traumatic stress

  10. ADCYAP1R1 genotype may have a role in post-traumatic stress symptoms in highly traumatized African-American females

Mouse (Murine) Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I (ADCYAP1R1) Interaktionspartner

  1. The results suggested that sympathetic nerve innervation may be responsible for Pituitary adenylate cyclase-activating polypeptide (zeige ADCYAP1 Proteine)-regulated hematopoiesis in bone marrow, mainly via PAC1.

  2. PACAP (zeige ADCYAP1 Proteine)/PAC1 signaling has a role in light regulated food anticipatory activity

  3. PAC1 plays a prominent role in chronic restraint stress response, but less so in the acute restraint stress response.

  4. overexpression of Pac1 rescued the Zac1 (zeige PLAGL1 Proteine) knockdown neuronal migration phenotype

  5. PAC1 has ligand-independent and dimer-dependent intrinsic/basal activity, conferring cells with anti-apoptotic activities against serum withdrawal, which is involved in the Wnt (zeige WNT2 Proteine)/beta-catenin (zeige CTNNB1 Proteine) signal and is associated with the endocytosis of PAC1 dimers.

  6. PACAP (zeige ADCYAP1 Proteine) and PAC1-R expression increased in cumulus cells isolated at different times after treatment with human chorionic gonadotropin.

  7. These results suggest that Sp1 (zeige SP1 Proteine) cross-linking might be crucial in negative regulation of PAC1 gene expression due to TG2 (zeige TGM2 Proteine) in OGD (zeige FGFR1 Proteine)-induced ER stress.

  8. This study demonistrated that pac1r expression in reactive astrocytes induced by global brain ischemia in mice.

  9. PAC1R mRNA expression in the hippocampus was significantly elevated on day 7 after ischemia induced by bilateral common carotid artery occlusion. .

  10. PAC1R transcript expression exhibited differential responses in NGF-OE mice that were tissue (urothelium vs. detrusor) cyclophosphamide-induced-cystitis duration-dependent.

Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I (ADCYAP1R1) Protein Überblick

Protein Überblick

This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified.

Alternative names and synonyms associated with Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I (ADCYAP1R1)

  • adenylate cyclase activating polypeptide 1 (pituitary) receptor type I (ADCYAP1R1)
  • adenylate cyclase activating polypeptide 1 receptor 1 (Adcyap1r1)
  • adenylate cyclase activating polypeptide 1 (pituitary) receptor type I (adcyap1r1)
  • adenylate cyclase activating polypeptide 1 receptor 1a (adcyap1r1a)
  • adenylate cyclase activating polypeptide 1 receptor 1 (adcyap1r1)
  • adenylate cyclase activating polypeptide 1 (pituitary) receptor type I (LOC100217843)
  • 2900024I10Rik Protein
  • ADCYAP1R1 Protein
  • adcyap1r1-A Protein
  • AI846590 Protein
  • pac1 Protein
  • PAC1-R Protein
  • PAC1R Protein
  • PACAP-R1 Protein
  • PACAP-R1A Protein
  • PACAP1-R Protein
  • pacapr Protein
  • PACAPR1 Protein
  • PACAPR1A Protein
  • pacapri Protein

Bezeichner auf Proteinebene für ADCYAP1R1

PACAP receptor 1 , PACAP type I receptor , PACAP-R1 , pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop , pituitary adenylate cyclase-activating polypeptide type I receptor , PACAP-R-1 , type I adenylate cyclase activating polypeptide receptor , PACAP type IA receptor , PACAP-R-1A , adenylate cyclase activating polypeptide 1 (pituitary) receptor type I , adenylate cyclase activating polypeptide 1 type 1 receptor , pituitary adenylate cyclase activating polypeptide 1 receptor (1) , pituitary adenylate cyclase activating polypeptide receptor , pituitary adenylate cyclase-activating polypeptide type IA receptor , PAC1 receptor , PAC1B , PAC1a-R , adenylate cyclase activating polypeptide 1 receptor 1 , pituitary adenylate cyclase activating polypeptide 1 receptor

GENE ID SPEZIES
117 Homo sapiens
11517 Mus musculus
780260 Xenopus (Silurana) tropicalis
24167 Rattus norvegicus
541315 Danio rerio
100136670 Oncorhynchus mykiss
319095 Bos taurus
373615 Xenopus laevis
420386 Gallus gallus
472340 Pan troglodytes
482386 Canis lupus familiaris
100009032 Oryctolagus cuniculus
100217843 Taeniopygia guttata
100511793 Sus scrofa
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