Smooth Muscle Actin (ACTA2) ELISA Kits

Bezeichnung:
Actin, alpha 2, Smooth Muscle, Aorta ELISA Kits (ACTA2)
Auf www.antikoerper-online.de finden Sie aktuell 29 Actin, alpha 2, Smooth Muscle, Aorta (ACTA2) ELISA Kits von 9 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Smooth Muscle Actin Antikörper (274) und Smooth Muscle Actin Proteine (11) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 321 Smooth Muscle Actin Produkte verfügbar.
Synonyme:
0610041G09Rik, a-SMA, AAT6, ACT-4, ACTA2, actc1, ACTSA, Actvs, alphaSMA, asma, MYMY5, sm-actin, SMactin, SMalphaA, wu:fb63d03

Am meisten referenzierte Smooth Muscle Actin ELISA Kits

  1. Human Smooth Muscle Actin ELISA Kit für Sandwich ELISA - ABIN364996 : Liu, Tu, Deng, Liang: The S protein of hepatitis B virus promotes collagen type I expression in hepatic stellate cells by virtue of hepatocytes. in Biomedical reports 2014 (PubMed)

  2. Human Smooth Muscle Actin ELISA Kit für Sandwich ELISA - ABIN2014301 : Xie, Wen, Yan, Wang, Wang, Chen, Li, Xu, Zhong, Shen, Chu: Toxoplasma gondii GRA15II effector-induced M1 cells ameliorate liver fibrosis in mice infected with Schistosomiasis japonica. in Cellular & molecular immunology 2016 (PubMed)

  3. Rat (Rattus) Smooth Muscle Actin ELISA Kit für Sandwich ELISA - ABIN578164 : Graupp, Gruber, Weiss, Kiesler, Bachna-Rotter, Friedrich, Gugatschka: Establishing principles of macromolecular crowding for in vitro fibrosis research of the vocal fold lamina propria. in The Laryngoscope 2014 (PubMed)

Weitere ELISA Kits für Smooth Muscle Actin Interaktionspartner

Xenopus laevis Actin, alpha 2, Smooth Muscle, Aorta (ACTA2) Interaktionspartner

  1. Data show that the locomotion and blebbing of the primordial germ cells (PGCs) required F-actin, myosin II activity and RhoA/Rho-associated protein kinase (ROCK) signaling.

Human Actin, alpha 2, Smooth Muscle, Aorta (ACTA2) Interaktionspartner

  1. Cells in high glucose for 7 days showed a significant decrease in mRNA expression of CD31 (zeige HBA1 ELISA Kits) and VE-cadherin (zeige CDH5 ELISA Kits), and a significant increase in that of alpha-SMA (zeige SMN1 ELISA Kits) and collagen I.

  2. ACTA2 is the isoform of contractile protein (zeige TNNT2 ELISA Kits) alpha-actin present in vascular smooth muscle cells (SMCs) throughout the arterial tree.4 Pathologic conditions in individuals with ACTA2 mutations show increased deposition of SMCs in the intimal arterial layer, leading to a decreased intraluminal diameter.4

  3. Two novel actin alpha 2 mutations (N117I and L348R) were identified in each familial non-syndromatic thoracic aortic aneurysm proband separately, and an additional novel actin alpha 2 mutation (Y168N) was identified in one patient with sporadic non-syndromatic thoracic aortic aneurysm.

  4. The R179H mutation has the potential to affect actin structure and function in both the contractile domain of the cell and the more dynamic cytoskeletal pool of actin, both of which are required for contraction.

  5. site-directed mutagenesis revealed several basic amino acid residues in the intermolecular (R267) and intramolecular (K82 and R159) subdomains that are essential for Purbeta (zeige PURB ELISA Kits) transcriptional repressor function in Acta2 promoter-reporter assays. In keeping with their diminished Acta2 repressor activity in fibroblasts, purified Purbeta (zeige PURB ELISA Kits) variants containing an R267A mutation exhibited reduced binding affinity for purine-ric (zeige FXYD5 ELISA Kits)...

  6. Data show that the expression profiles of three proteins: E-cadherin (zeige CDH1 ELISA Kits), Snail (zeige SNAI1 ELISA Kits), and alpha-smooth muscle actin (zeige ACTG2 ELISA Kits) were significantly different in extraprostatic extension prostate cancer (PCa (zeige FLVCR1 ELISA Kits)) compared with intra-prostatic tumour.

  7. ACTA2 mutations are associated with structural disruption and functional impairment of contractile proteins, and predispose to a variety of diffuse vascular diseases including TAAD, CAD (zeige CAD ELISA Kits), ischemic strokes, and Moyamoya disease. Vascular SMCs are also implicated in vascular remodeling in both physiological and pathological conditions.

  8. Parenchymal alphaSMA expression in hepatic tissue appeared to increase only among hepatitis C subjects with fibrosis 3-4.

  9. Multisystemic smooth muscle dysfunction syndrome secondary to an ACTA2 mutation.

  10. alpha-SMA expression, and MLC phosphorylation, whereas butaprost inhibited TGF-beta2-induced CPCG contraction, actin polymerization, and MLC phosphorylation.

Mouse (Murine) Actin, alpha 2, Smooth Muscle, Aorta (ACTA2) Interaktionspartner

  1. Gremlin1 accelerates hepatic stellate cell activation through upregulation of TGF-B1, alpha-SMA (zeige SMN1 ELISA Kits), and COL1a1 (zeige COL1A1 ELISA Kits) expression in a liver fibrosis disease model.

  2. Disruption of smooth muscle Acta2 increases reactive oxygen species levels, activates NF-kappaB (zeige NFKB1 ELISA Kits) signaling and increases AngII receptor type I a expression.

  3. The expression levels of alpha-smooth muscle actin (zeige ACTG2 ELISA Kits) (alpha-SMA (zeige SMN1 ELISA Kits), a marker of fibroblast activation) in fibrotic livers were significantly higher than those in control livers.

  4. this study identifies Rac1 as a downstream target for SMA (zeige SMN1 ELISA Kits) to inhibit smooth muscle cell proliferation and migration.

  5. the coordinated up-regulations of desmin (zeige DES ELISA Kits) and alpha- actinin (zeige ACTN1 ELISA Kits) specifically in the early stage of diastolic heart failure mouse models indicate a novel myocardial response.

  6. site-directed mutagenesis revealed several basic amino acid residues in the intermolecular (R267) and intramolecular (K82 and R159) subdomains that are essential for Purbeta (zeige PURB ELISA Kits) transcriptional repressor function in Acta2 promoter-reporter assays. In keeping with their diminished Acta2 repressor activity in fibroblasts, purified Purbeta (zeige PURB ELISA Kits) variants containing an R267A mutation exhibited reduced binding affinity for purine-ric (zeige FXYD5 ELISA Kits)...

  7. Alpha-smooth muscle actin (zeige ACTG2 ELISA Kits) protein (zeige ACTR3 ELISA Kits) and mRNA are enhanced from brain blood vessels in an Alzheimer's disease animal model.

  8. Astragaloside can delay the renal fibrosis process in diabetic mice by influencing the TGF-beta (zeige TGFB1 ELISA Kits)/SMADS signaling pathway and down-regulating TGF-beta1 (zeige TGFB1 ELISA Kits), SMAD2 (zeige SMAD2 ELISA Kits)/3, and alpha-SMA (zeige SMN1 ELISA Kits) expression.

  9. The increased expressions of the cartilage-associated proteins Collagen2 and alpha-SMA (zeige SMN1 ELISA Kits) during scleral chondrogenesis accompany myopia development.

  10. Results suggest that the atypical motif asparaging-cysteine-systeine Asn(17)-Cys(18)-Cys(19) is crucial for the normal surface trafficking and function of hydroxycarboxylic acid receptor 2 protein hGPR109A.

Rabbit Actin, alpha 2, Smooth Muscle, Aorta (ACTA2) Interaktionspartner

  1. TnT has a previously unrecognized role in forming the inactive state of regulated actin.

  2. The terminal pointed end subunit is tilted (zeige OTOP1 ELISA Kits) towards the penultimate subunit, allowing specific and extra loop-to-loop inter-strand contacts between the two end subunits, which is not possible in other parts of the filament.

  3. There was no significant change in the expression of TGF-beta(2 (zeige TGFB2 ELISA Kits)) and alpha-SMA (zeige SMN1 ELISA Kits) after laser-assisted intrastromal scanning.

  4. The arrangement of actin subunits in an actin dimer assembled by tandem W domains resembles that of a long-pitch helix of the actin filament.

  5. The distribution of laminin and alphaSMA in the testis and epididymis might point out to their roles in the male reproduction.

Smooth Muscle Actin (ACTA2) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Alternative names and synonyms associated with Smooth Muscle Actin (ACTA2)

  • actin, alpha 2, smooth muscle, aorta (acta2) Elisa Kit
  • actin, alpha 2, smooth muscle, aorta (ACTA2) Elisa Kit
  • actin, alpha 2, smooth muscle, aorta (Acta2) Elisa Kit
  • 0610041G09Rik Elisa Kit
  • a-SMA Elisa Kit
  • AAT6 Elisa Kit
  • ACT-4 Elisa Kit
  • ACTA2 Elisa Kit
  • actc1 Elisa Kit
  • ACTSA Elisa Kit
  • Actvs Elisa Kit
  • alphaSMA Elisa Kit
  • asma Elisa Kit
  • MYMY5 Elisa Kit
  • sm-actin Elisa Kit
  • SMactin Elisa Kit
  • SMalphaA Elisa Kit
  • wu:fb63d03 Elisa Kit

Bezeichner auf Proteinebene für ACTA2

SM actin , alpha smooth muscle actin , alpha-SM-actin , actin, alpha 2, smooth muscle, aorta , actin alpha cardiac 1 , actin, aortic smooth muscle , vascular smooth muscle alpha-actin , alpha-smooth muscle actin , actin, aortic smooth muscle-like , alpha-cardiac actin , cell growth-inhibiting gene 46 protein , actin, alpha, vascular smooth muscle , alpha-actin-2 , alpha actin 2 , alpha-actin , smooth muscle alpha-actin , alpha actin

GENE ID SPEZIES
431847 Xenopus laevis
477587 Canis lupus familiaris
496696 Xenopus (Silurana) tropicalis
733615 Sus scrofa
100074413 Ornithorhynchus anatinus
100173819 Pongo abelii
466148 Pan troglodytes
100062175 Equus caballus
100396597 Callithrix jacchus
100427024 Macaca mulatta
100579983 Nomascus leucogenys
59 Homo sapiens
11475 Mus musculus
322509 Danio rerio
515610 Bos taurus
423787 Gallus gallus
100009271 Oryctolagus cuniculus
81633 Rattus norvegicus
100722917 Cavia porcellus
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