anti-RYR2 (RYR2) Antikörper

anti-Ryanodine Receptor 2 (Cardiac) Antikörper (RYR2)
Auf finden Sie aktuell 37 Ryanodine Receptor 2 (Cardiac) (RYR2) Antikörper von 11 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen RYR2 Kits (9) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 50 RYR2 Produkte verfügbar.
9330127I20Rik, ARVC2, ARVD2, RyR, RYR-2, RYR2, VTSIP

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Weitere Antikörper gegen RYR2 Interaktionspartner

Rabbit Ryanodine Receptor 2 (Cardiac) (RYR2) Interaktionspartner

  1. Two regions of the ryanodine receptor (zeige RYR3 Antikörper) calcium channel are involved in Ca(2 (zeige CA2 Antikörper)+)-dependent inactivation

  2. [REVIEW] The efficacy of divalent calcium ion (Ca2 (zeige CA2 Antikörper)+) release in the myocardium depends on the amount of Ca2 (zeige CA2 Antikörper)+ loaded into the Ca2 (zeige CA2 Antikörper)+ store and the way in which this Ca2 (zeige CA2 Antikörper)* load influences the activity of the ryanodine receptor (zeige RYR3 Antikörper) Ca2+ release channel (RyR2).

  3. There were substantial transmural gradients in Cav1.2 (zeige CACNA1C Antikörper), KChIP2 (zeige KCNIP2 Antikörper), ERG (zeige KCNH2 Antikörper), KvLQT1 (zeige KCNQ1 Antikörper), Kir2.1 (zeige KCNJ2 Antikörper), NCX1 (zeige SLC8A1 Antikörper), SERCA2a (zeige ATP2A2 Antikörper) and RyR2 at the mRNA and, in some cases, protein level-in every case the mRNA or protein was more abundant in the epicardium than the endocardium.

  4. phosphorylation and K201 acted similarly to change the conformation of RyR1/2 and regulate FKBP12/12.6 binding.

Human Ryanodine Receptor 2 (Cardiac) (RYR2) Interaktionspartner

  1. The left atrium / right atrium expression ratio was significantly increased in Atrial fibrillation for ryanodine receptor 2 - gene related to calcium uptake and release, and located on the sarcoplasmic reticulum membrane.

  2. a direct interaction exists between RyR2 and CSQ2, is reported.

  3. In a national cohort of RyR2 mutation-positive CPVT patients, SCD (zeige SCD Antikörper), ASCD and syncope were presenting events in the majority of probands and also occurred in 36% of relatives identified through family screening.

  4. We identified a variant in the RYR2 gene (NM_001035) which involved a change of a glycine to an arginine in position155 of the gene product (c.463G > A, p.Gly155Arg, p.G155R). This RYR2 gene mutation is a novel rare genetic variant as it was not present in any of the international databases consulted.

  5. Data suggest that post-translational modifications (phosphorylation, oxidation, and nitrosylation) of RyR2 (ryanodine receptor 2) occur downstream of production of amyloid beta-peptides through ADRB2 (beta2-adrenergic receptor (zeige ADRB2 Antikörper)) Ca2 (zeige CA2 Antikörper)+ signaling cascade that activates PKA (protein kinase A).

  6. The unique properties of the CaM (zeige CALM1 Antikörper)-F142L mutation may provide novel clues on how to suppress excessive RyR2 Ca(2 (zeige CA2 Antikörper)+) release by manipulating the CaM (zeige CALM1 Antikörper)-RyR2 interaction.

  7. Cardiac adrenergic response and progression towards HF proceed unaltered in mice harboring the RyR2-S2808A mutation. Preventing RyR2-S2808 phosphorylation does not preclude a normal sympathetic response nor mitigates the pathophysiological consequences of MI.

  8. These results also suggest that altered cytosolic Ca(2 (zeige CA2 Antikörper)+) activation of RyR2 represents a common defect of RyR2 mutations associated with catecholaminergic polymorphic ventricular tachycardia and atrial fibrillation, which could potentially be suppressed by carvedilol or (R)-carvedilol.

  9. CaM (zeige CALM1 Antikörper) and S100A1 (zeige S100A1 Antikörper) can concurrently bind to and functionally modulate RyR1 (zeige RYR1 Antikörper) and RyR2, but this does not involve direct competition at the RyR (zeige RYR1 Antikörper) CaM (zeige CALM1 Antikörper) binding site.

  10. Long-Term Prognosis of Catecholaminergic Polymorphic Ventricular Tachycardia Patients With Ryanodine Receptor (zeige RYR3 Antikörper) (RYR2) Mutations.

Mouse (Murine) Ryanodine Receptor 2 (Cardiac) (RYR2) Interaktionspartner

  1. InsP3 dependent sarcoplasmic reticulum-Ca2 (zeige CA2 Antikörper)+ flux constitute the main mechanism of functional crosstalk between InsP3R2 (zeige ITPR2 Antikörper) and RyR2 resulting in more Ca2 (zeige CA2 Antikörper)+ sensitized RyRs to trigger subsequent Ca2 (zeige CA2 Antikörper)+-induced Ca2 (zeige CA2 Antikörper)+ release activation.

  2. The heart contraction is controlled by the Ca2 (zeige CA2 Antikörper)+-induced Ca2 (zeige CA2 Antikörper)+ release between L-type Ca2 (zeige CA2 Antikörper)+ channels and ryanodine receptors. RyRs became more sensitive to Ca2 (zeige CA2 Antikörper)+ triggers without FKBP12.6 (zeige FKBP1B Antikörper), leading to ventricular arrthymias.

  3. Allele-specific silencing of RYR2 prevents life-threatening arrhythmias in genetic carriers.

  4. Redox modification of RyR2 synergistically with CaMKII (zeige CAMK2G Antikörper) phosphorylation modulates reperfusion arrhythmias.

  5. These results demonstrate that Ryr2 controls mitochondrial Ca(2 (zeige CA2 Antikörper)+) dynamics and plays a specific, critical role in promoting glucose oxidation in cardiomyocytes. These findings indicate that partial RYR2 loss is sufficient to cause metabolic abnormalities seen in heart disease.

  6. data suggest that interactions between the cytoplasmic region of S6 and the U motif of RyR2 are important for stabilizing the closed state of the channel. Mutations in the S6/U motif domain interface likely destabilize the closed state of RyR2

  7. these results suggest that neuronal RyR2 Ca(2 (zeige CA2 Antikörper)+) leak due to Calstabin2 (zeige FKBP1B Antikörper) deletion contributes to learning deficiency and memory impairment.

  8. Nav1.5 (zeige SCN5A Antikörper) is downregulated and INa (zeige INA Antikörper) is reduced in RyR2-P2328S ventricles.

  9. The minimal KEKE motif of TRN (zeige TNPO1 Antikörper) involved in the interactions with CSQ2, HRC (zeige HRC Antikörper) and RyR2 within the Ca2 (zeige CA2 Antikörper)+ release units of cardiac sarcoplasmic reticulum has been defined.

  10. Inhibition of RyR2 phosphorylation can suppress sarcoplasmic reticulum Ca(2 (zeige CA2 Antikörper)+) leak in mdx (zeige DMD Antikörper) mouse hearts in part by reducing RyR2 oxidation.

RYR2 Antigen-Profil

Beschreibung des Gens

This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia.

Alternative names and synonyms associated with RYR2

  • ryanodine receptor 2 (cardiac) (RYR2) Antikörper
  • ryanodine receptor 2-like (LOC537376) Antikörper
  • cardiac ryanodine receptor (RYR-2) Antikörper
  • ryanodine receptor 2 (cardiac) (Ryr2) Antikörper
  • ryanodine receptor 2, cardiac (Ryr2) Antikörper
  • 9330127I20Rik Antikörper
  • ARVC2 Antikörper
  • ARVD2 Antikörper
  • RyR Antikörper
  • RYR-2 Antikörper
  • RYR2 Antikörper
  • VTSIP Antikörper

Bezeichner auf Proteinebene für RYR2

cardiac muscle ryanodine receptor , ryanodine receptor 2 (cardiac) , ryanodine receptor 2-like , Ca2+ release channel , cardiac muscle ryanodine receptor-calcium release channel , cardiac muscle-type ryanodine receptor , ryanodine receptor 2 , type 2 ryanodine receptor , cardiac ryanodine receptor 2 , cardiac-type ryanodine receptor , islet-type ryanodine receptor , kidney-type ryanodine receptor , ryanodine receptor type II , calcium release channel , ryanodine receptor type 2

457846 Pan troglodytes
100028207 Monodelphis domestica
100057437 Equus caballus
100406916 Callithrix jacchus
537376 Bos taurus
100009536 Oryctolagus cuniculus
403615 Canis lupus familiaris
100731307 Cavia porcellus
6262 Homo sapiens
689560 Rattus norvegicus
20191 Mus musculus
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