ECH1 Proteine (ECH1)

Bezeichnung:
Enoyl Coenzyme A Hydratase 1, Peroxisomal Proteine (ECH1)
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Synonyme:
AA617331, HPXEL, Pxel
alle Proteine anzeigen Gen GeneID UniProt
ECH1 1891 Q13011
Ratte ECH1 ECH1 64526 Q62651
ECH1 51798 O35459

Weitere Synonyme anzeigen

ECH1 Proteine (ECH1) nach Spezies

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Am meisten referenzierte ECH1 Proteine

  1. Human ECH1 Protein expressed in Escherichia coli (E. coli) - ABIN667209 : FitzPatrick, Germain-Lee, Valle: Isolation and characterization of rat and human cDNAs encoding a novel putative peroxisomal enoyl-CoA hydratase. in Genomics 1995 (PubMed)
    Zeige alle 2 Referenzen für 667209

  2. Human ECH1 Protein expressed in Escherichia coli (E. coli) - ABIN2006264 : Kovalyov, Kovalyova, Kovalyov, Serebryakova, Moshkovskii, Shishkin: Polymorphism of delta3,5-delta2,4-dienoyl-coenzyme A isomerase (the ECH1 gene product protein) in human striated muscle tissue. in Biochemistry. Biokhimii?a 2006 (PubMed)

Weitere Proteine zu ECH1 Interaktionspartnern

Human Enoyl Coenzyme A Hydratase 1, Peroxisomal (ECH1) Interaktionspartner

  1. Polymorphism of delta3,5-delta2,4-dienoyl-coenzyme A isomerase (the ECH1 gene product protein) in human striated (zeige NSDHL Proteine) muscle tissue

  2. Possible roles for the ECH1 protein product in peroxisomal beta-oxidation are discussed.

Mouse (Murine) Enoyl Coenzyme A Hydratase 1, Peroxisomal (ECH1) Interaktionspartner

  1. current work indicates the involvement of Ech1 in tumor metastasis development and progression, but the subcellular location of Ech1 has not much contribution to that.

  2. Down-regulation of Ech1 can inhibit the adhesive capacity of metastatic Hca-F cells.

  3. Down-regulation of ECH1 could inhibit the cell proliferation and migration of Hca-F hepatocarcinoma cells.

  4. The downregulation of Ech1 inhibited proliferation of the Hca-F cells, increased the ratio of Hca-F cells in S phase to G(1) phase and decreased the adhesion and migration capacities of Hca-F cells.

  5. disruption of peroxisomal fatty acid beta-oxidation at the level of enoyl-CoA hydratase/L-3-hydroxyacyl-CoA dehydrogenase (L-PBE) in mice leads to the induction of many of the PPARalpha (zeige PPARA Proteine) target genes independently of peroxisome proliferation in hepatocytes

ECH1 Protein Überblick

Protein Überblick

This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.

Alternative names and synonyms associated with ECH1

  • enoyl CoA hydratase 1, peroxisomal (ech1)
  • enoyl CoA hydratase 1, peroxisomal (ECH1)
  • enoyl CoA hydratase 1, peroxisomal (Ech1)
  • enoyl coenzyme A hydratase 1, peroxisomal (Ech1)
  • AA617331 Protein
  • HPXEL Protein
  • Pxel Protein

Bezeichner auf Proteinebene für ECH1

enoyl Coenzyme A hydratase 1, peroxisomal , delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial , peroxisomal enoyl-coenzyme A hydratase-like protein , delta3,5-delta2,4-dienoyl-CoA isomerase , dienoyl-CoA isomerase , peroxisomal enoyl-CoA hydratase 1 , peroxisomal enoyl coenzyme A hydratase 1 , ECH1-like protein , Peroxisomal enoyl hydratase-like protein , enoyl coenzyme A hydratase 1, peroxisomal , enoyl hydratase-like protein peroxisomal , enoyl hydratase-like protein, peroxisomal , peroxisomal/mitochondrial dienoyl-CoA isomerase

GENE ID SPEZIES
448218 Xenopus (Silurana) tropicalis
100171488 Pongo abelii
694324 Macaca mulatta
747511 Pan troglodytes
444770 Xenopus laevis
1891 Homo sapiens
476467 Canis lupus familiaris
733679 Sus scrofa
507431 Bos taurus
64526 Rattus norvegicus
51798 Mus musculus
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