ACAA2 Proteine (ACAA2)

Bezeichnung:
Acetyl-CoA Acyltransferase 2 Proteine (ACAA2)
Auf www.antikoerper-online.de finden Sie aktuell 14 Acetyl-CoA Acyltransferase 2 (ACAA2) Proteine von 7 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen ACAA2 Antikörper (57) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 75 ACAA2 Produkte verfügbar.
Synonyme:
0610011L04Rik, AI255831, AI265397, D18Ertd240e, DSAEC, ECHB, MTPB, TP-BETA
alle Proteine anzeigen Gen GeneID UniProt
ACAA2 10449 P42765
ACAA2 170465 P13437
ACAA2 52538 Q8BWT1

Weitere Synonyme anzeigen

ACAA2 Proteine (ACAA2) nach Spezies

Wählen Sie die gewünschte Spezies

Am meisten referenzierte ACAA2 Proteine

  1. Human ACAA2 Protein expressed in Escherichia coli (E. coli) - ABIN1098574 : Cao, Liu, Tang, Bao, Shen, Yuan, Zhao, Lu: Acetyl-Coenzyme A acyltransferase 2 attenuates the apoptotic effects of BNIP3 in two human cell lines. in Biochimica et biophysica acta 2008 (PubMed)

Weitere Proteine zu ACAA2 Interaktionspartnern

Human Acetyl-CoA Acyltransferase 2 (ACAA2) Interaktionspartner

  1. Exposure to bezafibrate (400 muM for 48 h) increased the abundance of HADHA (zeige HADHA Proteine) and HADHB (zeige HADHB Proteine) mRNAs.

  2. nonstructural protein 5 (zeige CAPS Proteine) (NS5 (zeige RAF1 Proteine)) interacted with hydroxyacyl-CoA dehydrogenase (zeige HADH Proteine) alpha and beta subunits, two components of the mitochondrial trifunctional protein (MTP (zeige MT1B Proteine)) involved in LCFA beta-oxidation

  3. Mutations in HADHB, which encodes the beta-subunit of mitochondrial trifunctional protein, cause infantile onset hypoparathyroidism and peripheral polyneuropathy.

  4. Heterozygous mutation in HADHB (zeige HADHB Proteine) gene cause early-onset axonal axonal Charcot-Marie-tooth disease.

  5. The results demonstrated that ERbeta (zeige ESR2 Proteine) was indeed associated and colocalized with HADHB (zeige HADHB Proteine) within mitochondria.

  6. HADHB (zeige HADHB Proteine) is a functional molecular target of estrogen receptor alpha (zeige ESR1 Proteine) in the mitochondria, and the interaction may play an important role in the estrogen-mediated lipid metabolism in animals and humans.

  7. mutational analysis of the HADHB (zeige HADHB Proteine) gene, which encodes long-chain 3-ketoacyl-CoA thiolase (zeige HADHB Proteine), identified compound heterozygous mutations of c.520C>T (p.R141C) and c.1331G>A (p.R411K) in a case of mitochondrial trifunctional protein deficiency

  8. Results emphasize the value of cDNA analysis in the characterization of HADHA (zeige HADHA Proteine) and HADHB (zeige HADHB Proteine) mutations and further strengthen the model of haploinsufficiency as a major pathomechanism in MTP (zeige MT1B Proteine) defects.

  9. Recombinant mitochondrial trifunctional protein displayed 2-enoyl-CoA hydratase, l-3-hydroxyacyl-CoA dehydrogenase, and 3-ketoacyl-CoA thiolase (zeige HADHB Proteine) activities.

  10. The present findings showed that all missense mutations in HADHB (zeige HADHB Proteine) were disease-causing.

Mouse (Murine) Acetyl-CoA Acyltransferase 2 (ACAA2) Interaktionspartner

  1. Data show that the major mitochondrial partner of Shc (zeige SHC1 Proteine) adaptor protein p46Shc is the lipid oxidation enzyme 3-ketoacylCoA thiolase (zeige HADHB Proteine) ACAA2, to which p46Shc binds directly and with a strong affinity.

ACAA2 Protein Überblick

Protein Überblick

This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. Mutations in this gene result in trifunctional protein deficiency. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Alternatively spliced transcript variants have been found\; however, their full-length nature is not known.

Alternative names and synonyms associated with ACAA2

  • acetyl-CoA acyltransferase 2 (ACAA2)
  • hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit (HADHB)
  • acetyl-CoA acyltransferase 2 (Acaa2)
  • acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) (Acaa2)
  • acetyl-CoA acyltransferase 2 (acaa2)
  • 0610011L04Rik Protein
  • AI255831 Protein
  • AI265397 Protein
  • D18Ertd240e Protein
  • DSAEC Protein
  • ECHB Protein
  • MTPB Protein
  • TP-BETA Protein

Bezeichner auf Proteinebene für ACAA2

3-ketoacyl-CoA thiolase, mitochondrial , T1 , acetyl-Coenzyme A acyltransferase 2 , beta ketothiolase , beta-ketothiolase , mitochondrial 3-oxoacyl-CoA thiolase , mitochondrial 3-oxoacyl-Coenzyme A thiolase , 2-enoyl-Coenzyme A (CoA) hydratase, beta subunit , 3-ketoacyl-Coenzyme A (CoA) thiolase of mitochondrial trifunctional protein, beta subunit , acetyl-CoA acyltransferase , hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit , trifunctional enzyme subunit beta, mitochondrial , acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) , mitochondrial acetyl-Coenzyme A acyltransferase 2

GENE ID SPEZIES
10449 Homo sapiens
3032 Homo sapiens
170465 Rattus norvegicus
426847 Gallus gallus
522006 Bos taurus
100312959 Sus scrofa
52538 Mus musculus
380424 Xenopus laevis
Ausgewählte Anbieter für ACAA2 Proteine (ACAA2)
Haben Sie etwas anderes gesucht?