anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8) Antikörper

Bezeichnung:
anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) Antikörper (PSMB8)
Auf www.antikoerper-online.de finden Sie aktuell 102 Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8) Antikörper von 19 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) Proteine (17) und Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) Kits (9) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 137 Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) Produkte verfügbar.
Synonyme:
ALDD, ATP6V0D2, D6S216, D6S216E, JMP, Lmp-7, Lmp7, macropain, NKJO, prosome, PSMB5i, Ring10

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Am meisten referenzierte anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) Antikörper

  1. Human Polyclonal PSMB8 Primary Antibody für ICC, IF - ABIN267107 : Meister, Frey, Lang, Gaipl, Schett, Schlötzer-Schrehardt, Voll: Calcium channel blocker verapamil enhances endoplasmic reticulum stress and cell death induced by proteasome inhibition in myeloma cells. in Neoplasia (New York, N.Y.) 2010 (PubMed)
    Zeige alle 2 Referenzen für 267107

  2. Human Monoclonal PSMB8 Primary Antibody für ICC, IHC - ABIN969371 : Mehta, Jordanova, Corver, van Wezel, Uh, Kenter, Jan Fleuren: Single nucleotide polymorphisms in antigen processing machinery component ERAP1 significantly associate with clinical outcome in cervical carcinoma. in Genes, chromosomes & cancer 2009 (PubMed)
    Zeige alle 2 Referenzen für 969371

  3. Human Polyclonal PSMB8 Primary Antibody für ELISA, WB - ABIN4331261 : Schwarz, van Den Broek, Kostka, Kraft, Soza, Schmidtke, Kloetzel, Groettrup: Overexpression of the proteasome subunits LMP2, LMP7, and MECL-1, but not PA28 alpha/beta, enhances the presentation of an immunodominant lymphocytic choriomeningitis virus T cell epitope. in Journal of immunology (Baltimore, Md. : 1950) 2000 (PubMed)
    Zeige alle 2 Referenzen für 4331261

  4. Human Monoclonal PSMB8 Primary Antibody für IF - ABIN393460 : Hamamura, Chen, Nishimura, Tanjung, Sudo, Yokota: Predicting and validating the pathway of Wnt3a-driven suppression of osteoclastogenesis. in Cellular signalling 2014 (PubMed)

Weitere Antikörper gegen Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) Interaktionspartner

Human Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8) Interaktionspartner

  1. PSMB8 rs2071464 was associated with generalized and active vitiligo (zeige MITF Antikörper) from Gujarat whereas TAP1 (zeige TAP1 Antikörper) rs1135216 showed no association. The down-regulation of PSMB8 in patients with risk genotype 'CC' advocates the vital role of PSMB8 in the autoimmune basis of vitiligo (zeige MITF Antikörper).

  2. results suggest that PSMB8 is a predictive marker of preoperative radiosensitivity in locally advanced rectal cancer patients.

  3. Data show that tight junction protein 1 (TJP1 (zeige TJP1 Antikörper)) suppressed expression of the catalytically proteasome subunits LMP7 and LMP2 (zeige PSMB9 Antikörper), decreased proteasome activity, and enhanced proteasome inhibitor sensitivity in vitro and in vivo through suppression of EGFR (zeige EGFR Antikörper)/JAK1 (zeige JAK1 Antikörper)/STAT3 (zeige STAT3 Antikörper) signaling.

  4. there was no significant difference with respect to the genotypic frequencies of the SNPs in PSMB8, TAP1, and TAP2 loci in Parkinson's disease patients

  5. We described a Brazilian patient with CANDLE syndrome possessing a novel mutation in the PSMB8 gene.

  6. designed siRNAs that efficiently silence LMP2 (zeige PSMB9 Antikörper), LMP7 and MECL-1 (zeige PSMB10 Antikörper) gene expression.

  7. demonstrated that patients with the LMP-7 CA/AA genotypes were more likely to have advanced fibrosis scores than those bearing the CC genotype

  8. lupus nephritis showed up-regulation of the immunoproteasome subunit LMP7 in tubular epithelial cells associated with type I interferon (zeige IFNA Antikörper) signature.

  9. Comparison with reference profiles of sorted immune cells and healthy muscle confirmed upregulation of PSMB8 and -9 in myositis biopsies beyond infiltration related changes.

  10. The LMP7 gene promoter methylation and protein downregulation were correlated at high extent in Kazakh's ESCC patients, and may explain the epigenetic regulation on gene expression.

Mouse (Murine) Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8) Interaktionspartner

  1. The authors found that selective inhibition of LMP7 had neither an influence on allograft survival in an major histocompatibility complex-mismatch model nor in a multiple minor mismatch skin transplantation model.

  2. LMP7 deficiency decreased inflammatory responses such as macrophage infiltration and chemokine (zeige CCL1 Antikörper) expression while it increased serum adiponection levels.

  3. these data support that LMP7 inhibition in the context of BMT modulates allogeneic responses by decreasing endogenous miHA (zeige XIAP Antikörper) presentation and that the consequential reduction in allogeneic stimulation and cytokine production reduces GVHD development.

  4. PSMB8, ALDH1A1 (zeige ALDH1A1 Antikörper), and HSPA4 (zeige HSPA4 Antikörper) were identified to be located in ovarian tissues, to regulate 12 cellular pathways, and demonstrate age-dependent dynamic changes in expression profiling.

  5. Overexpression of the immunoproteasome LMP7 subunit in antigen-presenting cells due to lipopolysaccharide exposure as well as LMP7 expression in peripheral cells, are required for CD8 (zeige CD8A Antikörper)+ T-cell auto-reactivity.

  6. Data show that knockdown of i-proteasome catalytic subunit PSMB9 (zeige PSMB9 Antikörper) by short hairpin RNA (shRNA) decreased the expression of both PSMB9 (zeige PSMB9 Antikörper) and PSMB8 without affecting other catalytic subunits of the proteasome.

  7. we present novel evidence for the requirement of the beta5i immunosubunit to generate a strong Th2 response during OVA- but not HDM (zeige HDAC3 Antikörper)-induced acute asthma.

  8. Red blood cells of LMP7-deficient mice were more likely to deform in response to infection with malaria parasites, presumably resulting in higher susceptibility to phagocytosis and in the partial resistance to malaria.

  9. Deletion or inhibition of LMP7 suppresses generation of T helper (Th)17 cells but promotes regulatory T cell (Treg) development.

  10. Probeta5 predominantly promotes integration into LMP2 (zeige PSMB9 Antikörper)/MECL-1 (zeige PSMB10 Antikörper)-containing precursors in IFNgamma-stimulated, LMP7-deficient cells and infected LMP7-deficient mice.

Pig (Porcine) Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8) Interaktionspartner

  1. These results suggest LMP2 (zeige PSMB9 Antikörper)/LMP7 gene should be regarded as molecular marker to estimate animal's immune status for their effects on hematological traits.

Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8) Antigen-Profil

Beschreibung des Gens

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified\; both isoforms are processed to yield the same mature subunit.

Alternative names and synonyms associated with Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8)

  • proteasome (prosome, macropain) subunit, beta type, 8 (PSMB8) Antikörper
  • proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) (PSMB8) Antikörper
  • proteasome (prosome, macropain) subunit, beta type, 8 (psmb8) Antikörper
  • proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) (Psmb8) Antikörper
  • proteasome (prosome, macropain) subunit, beta type, 8 (Psmb8) Antikörper
  • ALDD Antikörper
  • ATP6V0D2 Antikörper
  • D6S216 Antikörper
  • D6S216E Antikörper
  • JMP Antikörper
  • Lmp-7 Antikörper
  • Lmp7 Antikörper
  • macropain Antikörper
  • NKJO Antikörper
  • prosome Antikörper
  • PSMB5i Antikörper
  • Ring10 Antikörper

Bezeichner auf Proteinebene für PSMB8

large multifunctional peptidase 7 , low molecular mass protein 7 , low molecular weight protein 7 , macropain subunit C13 , multicatalytic endopeptidase complex subunit C13 , protease component C13 , proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) , proteasome catalytic subunit 3i , proteasome component C13 , proteasome subunit Y2 , proteasome subunit beta 5i , proteasome subunit beta type-8 , proteasome-related gene 7 , really interesting new gene 10 protein , MHC class II DO beta , proteasome subunit beta-5i , proteasome (prosome, macropain) subunit, beta type, 8 , large multifunctional protease 7 , proteosome (prosome, macropain) subunit, beta type 8 , MC13 (LMP7) , proteasome subunit MC13 , proteosome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) , proteosome beta 8 subunit , low molecular mass polypeptide 7 , proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) , proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional protease 7) , proteasome beta 8 subunit , proteasome subunit LMP7 , macropain , proteasome subunit, beta type 8

GENE ID SPEZIES
5696 Homo sapiens
474865 Canis lupus familiaris
30666 Danio rerio
16913 Mus musculus
24968 Rattus norvegicus
396975 Sus scrofa
282013 Bos taurus
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