anti-Zebrafisch Proteasome (Prosome, Macropain) Subunit, beta Type, 5 Antikörper für Western Blotting

Recommended Proteasome (Prosome, Macropain) Subunit, beta Type, 5 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5) Antikörper
  • LMPX
  • MB1
  • X
  • etID309919.2
  • fb59c07
  • si:zc14a17.13
  • wu:fb59c07
  • x
  • zgc:86820
  • proteasome subunit beta 5
  • proteasome (prosome, macropain) subunit, beta type 5
  • proteasome subunit beta 5 L homeolog
  • proteasome (prosome, macropain) subunit, beta type, 5
  • PSMB5
  • psmb5
  • Psmb5
  • psmb5.L
Epitop
Middle Region
14
14
5
4
4
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Yeast, Zebrafisch
54
16
13
3
3
3
3
3
3
3
3
3
3
1
1
Wirt
Kaninchen
47
6
3
Klonalität
Polyklonal
Konjugat
Unkonjugiert
2
2
2
2
2
2
Applikation
Western Blotting (WB)
47
29
18
13
12
4
1
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN2786720
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN470013 WB Rabbit AA 72-121 Anmelden zum Anzeigen Polyclonal

General

Antigen Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5) Antikörper
Epitop Middle Region
(14), (14), (5), (4), (4), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Yeast, Zebrafisch
(54), (16), (13), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1), (1)
Wirt Kaninchen
(47), (6), (3)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(2), (2), (2), (2), (2), (2)
Applikation Western Blotting (WB)
(47), (29), (18), (13), (12), (4), (1), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN982353.
Sequenz IVAADSRATA GAYIASQTVK KVIEINPYLL GTMAGGAADC SFWERLLARQ
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 100%
Produktmerkmale This is a rabbit polyclonal antibody against PSMB5. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human PSMB5

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung PSMB5 (PSMB5 Antibody Abstract)
Hintergrund The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMB5 is a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit).The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: LMPX, MB1, MGC104214, X
Protein Interaction Partner: UBC, AURKA, PSMD14, BMI1, PSMG3, PSMB8, PSMB7, PSMB6, PYCRL, AP3M1, RPP38, PSMB4, PSMB3, PSMB2, PSMB1, PSMA7, PSMA6, PSMA5, PSMA4, PSMA3, PSMA1, KIF5B, EPB41L1, CAST, XRN1, CDK20, CDKL1, PSMA2, PARK2, BAG3, IQCB1, HSP90AB1, HSP90AA1, FN1, IKBKAP, PSMA8, P
Protein Size: 263
Molekulargewicht 28 kDa
Gen-ID 5693
NCBI Accession NM_002797, NP_002788
UniProt P28074
Forschungsgebiet Proteolysis / Ubiquitin, Proteasome
Pathways Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 263 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Referenzen Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, 2007

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5) (Middle Region) antibody (ABIN2786720) WB Suggested Anti-PSMB5 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: