Proteasome (Prosome, Macropain) Subunit, beta Type, 4 Proteine (PSMB4)

Auf www.antikoerper-online.de finden Sie aktuell 11 Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4) Proteine von 5 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Proteasome (Prosome, Macropain) Subunit, beta Type, 4 Antikörper (118) und Proteasome (Prosome, Macropain) Subunit, beta Type, 4 Kits (11) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 148 Proteasome (Prosome, Macropain) Subunit, beta Type, 4 Produkte verfügbar.
Synonyme:
An18g06680, HN3, HsN3, im:6909492, PROS-26, Pros-27, PROS26, PSMB4, zgc:110330
alle Proteine anzeigen Gen GeneID UniProt
PSMB4 19172 P99026
PSMB4 58854 P34067
PSMB4 5692 P28070

Proteasome (Prosome, Macropain) Subunit, beta Type, 4 Proteine (PSMB4) nach Spezies

Weitere Proteine zu Proteasome (Prosome, Macropain) Subunit, beta Type, 4 Interaktionspartnern

Human Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4) Interaktionspartner

  1. We further identified miR (zeige MLXIP Proteine)-148b as a negative regulator of proteasome beta-4 subunit. Enforced expression of miR (zeige MLXIP Proteine)-148b resulted in vitro growth inhibition of melanoma cells, whereas this inhibition was further abolished by enforced expression of proteasome beta-4 subunit

  2. Our findings implied that PSMB4 is involved in the progression of EOC (epithelial ovarian cancer) and could serve as potential therapeutical target of EOC. These data suggested that PSMB4 may promote cell proliferation via the NF-kappaB (zeige NFKB1 Proteine)-target gene in EOC (epithelial ovarian cancer)

  3. Taken together, our results demonstrated that PSMB4 regulated MM cell growth in part by activating NF-kappaB (zeige NFKB1 Proteine)-miR (zeige MLXIP Proteine)-21 signaling, which may represent promising targets for novel specific therapies.

  4. Data indicate that recruitment of proteasomes into mutant huntingtin (zeige HTT Proteine) (mHTT) protein initiated inclusion bodies (IBs) was observed when the PSMB4-GFP was co-expressed with mHTT.

  5. proteasome subunit beta type 4 (PSMB4), the beta7 subunit of the 20S core complex, was identified as a direct binding partner of CRBN (zeige CRBN Proteine).

  6. While 26 proteasome dysfunction is observed in Parkinson's disease (PD), diverse mutations in the parkin (zeige PARK2 Proteine) gene are linked to early-onset autosomal-recessive forms of familial PD.

Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4) Protein Überblick

Protein Überblick

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.

Alternative names and synonyms associated with Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4)

  • proteasome subunit beta type-4 (ANI_1_890164)
  • proteasome (prosome, macropain) subunit, beta type, 4 (PSMB4)
  • proteasome (prosome macropain) subunit beta type 4 (psmb4)
  • proteasome (prosome, macropain) subunit, beta type 4 (Psmb4)
  • proteasome (prosome, macropain) subunit, beta type 4 (psmb4)
  • proteasome (prosome, macropain) subunit, beta type, 4 (psmb4)
  • An18g06680 Protein
  • HN3 Protein
  • HsN3 Protein
  • im:6909492 Protein
  • PROS-26 Protein
  • Pros-27 Protein
  • PROS26 Protein
  • PSMB4 Protein
  • zgc:110330 Protein

Bezeichner auf Proteinebene für PSMB4

proteasome (prosome, macropain) subunit, beta type, 4 , proteasome beta 4 subunit , low molecular mass protein 3 , macropain beta chain , multicatalytic endopeptidase complex beta chain , proteasome beta chain , proteasome chain 3 , proteasome subunit beta type-4 , RN3 , proteasome beta subunit , 26 kDa prosomal protein , hsBPROS26 , proteasome subunit HsN3 , proteasome subunit, beta type, 4

GENE ID SPEZIES
4990236 Aspergillus niger CBS 513.88
429986 Gallus gallus
457293 Pan troglodytes
496603 Xenopus (Silurana) tropicalis
19172 Mus musculus
58854 Rattus norvegicus
380584 Xenopus laevis
5692 Homo sapiens
475848 Canis lupus familiaris
100153923 Sus scrofa
506203 Bos taurus
100328673 Oryctolagus cuniculus
550499 Danio rerio
101116188 Ovis aries
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