anti-Kaninchen Proteasome (Prosome, Macropain) Subunit, alpha Type, 3 Antikörper für Western Blotting

Recommended Proteasome (Prosome, Macropain) Subunit, alpha Type, 3 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Proteasome (Prosome, Macropain) Subunit, alpha Type, 3 (PSMA3) Antikörper
  • psma3
  • Lmpc8
  • Psma3l
  • HC8
  • PSC3
  • im:6909944
  • zgc:114044
  • proteasome subunit alpha 3
  • proteasome (prosome, macropain) subunit, alpha type 3
  • proteasome subunit alpha 3 L homeolog
  • proteasome subunit alpha type 3-like
  • psma3
  • PSMA3
  • Psma3
  • psma3.L
  • Psma3l
Epitop
Middle Region
2
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Yeast, Zebrafisch
28
23
20
3
3
3
3
3
3
2
2
2
1
Wirt
Kaninchen
26
1
Klonalität
Polyklonal
Applikation
Western Blotting (WB)
26
13
6
6
5
2
1
1
Optionen
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2787366
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.197537 ABIN2787367 WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 1
1 ABIN470201 WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN2577375 IHC WB Mouse IgG2b Anmelden zum Anzeigen MCP257

General

Antigen Proteasome (Prosome, Macropain) Subunit, alpha Type, 3 (PSMA3) Antikörper
Epitop Middle Region
(2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Yeast, Zebrafisch
(28), (23), (20), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1)
Wirt Kaninchen
(26), (1)
Klonalität
Polyklonal
Applikation Western Blotting (WB)
(26), (13), (6), (6), (5), (2), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN982340.
Sequenz TCRDIVKEVA KIIYIVHDEV KDKAFELELS WVGELTNGRH EIVPKDIREE
Homologie Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 92%, Yeast: 77%, Zebrafish: 77%
Produktmerkmale This is a rabbit polyclonal antibody against PSMA3. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human PSMA3

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung PSMA3 (PSMA3 Antibody Abstract)
Hintergrund The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA3 is a member of the peptidase T1A family, that is a 20S core alpha subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.
Alias Symbols: HC8, MGC12306, MGC32631, PSC3
Protein Interaction Partner: SF1, STX4, SNRPC, SNRPB, RAB3IL1, PSMB4, PSMA6, PSMA3, PSMA1, NPPB, CTAGE5, LETM1, LASP1, KRAS, NPBWR2, GATA3, GATA2, CYBA, CST2, CDK6, ATP6V0C, DMC1, SLMO1, BTN2A2, STX6, SERF2, HUWE1, APLN, C1QTNF9B-AS1, C9orf106, KRTAP26-1, KRTAP19-5, KRTAP8-1, RTP5, R
Protein Size: 248
Molekulargewicht 28 kDa
Gen-ID 5684
NCBI Accession NM_152132, NP_687033
Pathways Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 248 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

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Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Proteasome (Prosome, Macropain) Subunit, alpha Type, 3 (PSMA3) (Middle Region) antibody (ABIN2787366) WB Suggested Anti-PSMA3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: