anti-PPP2R2A (PPP2R2A) Antikörper

Bezeichnung:
anti-Protein Phosphatase 2 Regulatory Subunit 2A Antikörper (PPP2R2A)
Auf www.antikoerper-online.de finden Sie aktuell 28 Protein Phosphatase 2 Regulatory Subunit 2A (PPP2R2A) Antikörper von 14 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen PPP2R2A Proteine (7) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 36 PPP2R2A Produkte verfügbar.
Synonyme:
2410004D02Rik, B55A, B55ALPHA, mKIAA1541, PPP2R2A, PR52A, PR55A

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anti-Mouse (Murine) PPP2R2A Antikörper:

anti-Human PPP2R2A Antikörper:

anti-Rat (Rattus) PPP2R2A Antikörper:

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Am meisten referenzierte anti-PPP2R2A Antikörper

  1. Human Polyclonal PPP2R2A Primary Antibody für WB - ABIN1881683 : Li, Cai, Shouse, Piluso, Liu: A specific PP2A regulatory subunit, B56gamma, mediates DNA damage-induced dephosphorylation of p53 at Thr55. in The EMBO journal 2007 (PubMed)
    Zeige alle 4 Referenzen für 1881683

Weitere Antikörper gegen PPP2R2A Interaktionspartner

Mouse (Murine) Protein Phosphatase 2 Regulatory Subunit 2A (PPP2R2A) Interaktionspartner

  1. Data suggest IGT10 mice, diabetes type 2 model, exhibit 2 genetic defects: haploinsufficiency (heterozygosity for null allele) of insulin receptor (Insr (zeige INSR Antikörper)); splice-site mutation in protein phosphatase 2 regulatory subunit B alpha (Ppp2r2a). Inheritance of either allele results in insulin (zeige INS Antikörper) resistance but not overt diabetes. Double heterozygosity leads to insulin (zeige INS Antikörper) resistance and diabetes type 2 without increase in body weight.

  2. Concurrent mTORC1 inactivation and PP2A (zeige PPP2R2B Antikörper)-B55alpha stimulation fuel ULK1 (zeige ULK1 Antikörper)-dependent autophagy.

  3. FBXL16 (zeige FBXL16 Antikörper) negatively regulates the activity of B55alpha-PP2A (zeige PPP2R2B Antikörper) to modulate the genesis of FLK1 (zeige KDR Antikörper)+ progenitor cells.

  4. Ppp2r2a is required for Connexin-43 (zeige GJA1 Antikörper) dephosphorlyation during epidermal barrier acquisition

  5. The B55alpha-EDD (zeige UBR5 Antikörper)-p53 (zeige TP53 Antikörper) pathway is essential for cancer cell survival and tumor growth under low glutamine (zeige GFPT1 Antikörper) conditions in vitro and in vivo.

  6. that B55alpha-dependent targeting of the PP2A (zeige PPP2R2B Antikörper) holoenzyme to Akt (zeige AKT1 Antikörper) selectively regulates Akt (zeige AKT1 Antikörper) phosphorylation at Thr (zeige TRH Antikörper)-308 to regulate cell proliferation and survival.

  7. PP-2A is less abundant than PP-1 (zeige PPP1CC Antikörper) in the mouse eye and appear to be highly regulated by various regulatory subunits; the genes encoding PP-1alpha/beta, PP-2Aalpha/beta, PP-2A-Aalpha/beta, and PP-2A-B alpha/beta/gamma are all differentially expressed.

Human Protein Phosphatase 2 Regulatory Subunit 2A (PPP2R2A) Interaktionspartner

  1. results suggest that PR55alpha promotes pancreatic cancer development by sustaining hyperactivity of multiple oncogenic signaling pathways, including AKT (zeige AKT1 Antikörper), ERK (zeige EPHB2 Antikörper), and Wnt (zeige WNT2 Antikörper)

  2. miR-222 targets protein phosphatase 2A subunit B in bladder cancer cells.

  3. miR (zeige MLXIP Antikörper)-556-5p functions as an onco-miRNA and participates in prostate cancer carcinogenesis by suppressing PPP2R2A expression.

  4. Concurrent mTORC1 inactivation and PP2A (zeige PPP2R4 Antikörper)-B55alpha stimulation fuel ULK1 (zeige ULK1 Antikörper)-dependent autophagy.

  5. Data show that breast cancer (BC) with PPP2R2A deletions are associated with worse overall survival, and the combination of altered PPP2R2A and high CCND1 (zeige CCND1 Antikörper) expression define a subgroup of luminal-like BC patients with a high risk of relapse and death.

  6. overexpression of miR (zeige MLXIP Antikörper)-892a may provide a selective growth promotion for colorectal cancer cells by direct suppression of PPP2R2A expression.

  7. miR (zeige MLXIP Antikörper)-136 may play an important role during TGF-beta1 (zeige TGFB1 Antikörper)-induced proliferation arrest by targeting PPP2R2A in keratinocytes.

  8. Data suggest livers of biliary atresia subjects exhibit overexpression of MIR222 (microRNA 222); this appears to contribute to liver fibrosis (and in vitro cell proliferation) by targeting PPP2R2A (protein phosphatase 2A subunit B) and Akt (zeige AKT1 Antikörper) signaling.

  9. The suppression of B55alpha activates signaling pathways that could support leukemia cell survival.

  10. Identification of the adenovirus E4orf4 protein binding site on the B55alpha and Cdc55 regulatory subunits of PP2A (zeige PPP2R4 Antikörper): Implications for PP2A (zeige PPP2R4 Antikörper)

Rabbit Protein Phosphatase 2 Regulatory Subunit 2A (PPP2R2A) Interaktionspartner

  1. Phosphorylation of T231 (AT180) can negatively influence the dephosphorylation of the pS202/pT205 AT8 epitope, even without an altered PP2A (zeige PPP2R2B Antikörper) pool.

PPP2R2A Antigen-Profil

Beschreibung des Gens

The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants have been described.

Alternative names and synonyms associated with PPP2R2A

  • protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform (Ppp2r2a) Antikörper
  • protein phosphatase 2, regulatory subunit B, alpha (PPP2R2A) Antikörper
  • protein phosphatase 2, regulatory subunit B, alpha (Ppp2r2a) Antikörper
  • protein phosphatase 2A1 B alpha subunit (LOC100328616) Antikörper
  • 2410004D02Rik Antikörper
  • B55A Antikörper
  • B55ALPHA Antikörper
  • mKIAA1541 Antikörper
  • PPP2R2A Antikörper
  • PR52A Antikörper
  • PR55A Antikörper

Bezeichner auf Proteinebene für PPP2R2A

PP2A subunit B isoform B55-alpha , PP2A subunit B isoform PR55-alpha , PP2A subunit B isoform R2-alpha , PP2A subunit B isoform alpha , serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform , protein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoform , protein phosphatase 2 (formerly 2A), regulatory subunit B (PR52), alpha isoform , serine/threonine protein phosphatase 2A, 55 KDA regulatory subunit B, alpha isoform , PP2A subunit B isoform BRA , PP2A, subunit B, B-alpha isoform , PP2A, subunit B, B55-alpha isoform , PP2A, subunit B, BRA isoform , PP2A, subunit B, PR55-alpha isoform , PP2A, subunit B, R2-alpha isoform , protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform

GENE ID SPEZIES
71978 Mus musculus
508045 Bos taurus
5520 Homo sapiens
117104 Rattus norvegicus
100328616 Oryctolagus cuniculus
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