anti-FBXO5 (FBXO5) Antikörper

anti-F-Box Protein 5 Antikörper (FBXO5)
Auf finden Sie aktuell 68 F-Box Protein 5 (FBXO5) Antikörper von 12 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen FBXO5 Kits (12) und FBXO5 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 89 FBXO5 Produkte verfügbar.
2510044I10Rik, ACYPI007854, C85305, Emi1, FBX5, Fbxo5, Fbxo31, fc65h02, wu:fc65h02, wu:fe06e07, wu:fz79f03, zgc:136397, zgc:158541
Alle Antikörper anzeigen Gen GeneID UniProt
FBXO5 26271 Q9UKT4
FBXO5 67141 Q7TSG3
FBXO5 292263  

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Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-FBXO5 (FBXO5) Antikörper

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anti-Human FBXO5 Antikörper:

anti-Mouse (Murine) FBXO5 Antikörper:

anti-Rat (Rattus) FBXO5 Antikörper:

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Am meisten referenzierte anti-FBXO5 Antikörper

  1. Dog (Canine) Polyclonal FBXO5 Primary Antibody für WB - ABIN2774700 : Estrabaud, Le Rouzic, Lopez-Vergès, Morel, Belaïdouni, Benarous, Transy, Berlioz-Torrent, Margottin-Goguet: Regulated degradation of the HIV-1 Vpu protein through a betaTrCP-independent pathway limits the release of viral particles. in PLoS pathogens 2007 (PubMed)

  2. Human Polyclonal FBXO5 Primary Antibody für EIA, WB - ABIN952292 : Lee, Kim, Barbier, Fotedar, Fotedar: DNA damage triggers p21WAF1-dependent Emi1 down-regulation that maintains G2 arrest. in Molecular biology of the cell 2009 (PubMed)

Weitere Antikörper gegen FBXO5 Interaktionspartner

Human F-Box Protein 5 (FBXO5) Interaktionspartner

  1. Examined eoffect of Emi1 over-expression on Skp2 expression in breast cancer. Found expression of Emi1 was positively related with Skp2 expression; Emi1 expression correlated significantly with histologic grade. Skp2 expression obtained similar results.

  2. Human papillomavirus type 16 E7 expression causes increased EMI1 mRNA expression and also inhibits EMI1 degradation.

  3. The C-terminal domain inhibits multiple APC/C(CDH1) functions. The intrinsically disordered D-box, linker & tail elements, & a structured Zn-binding domain synergistically block the substrate-binding site & inhibit ubiquitin-chain elongation.

  4. Emi1 depletion enhances the sensitivity of cancer cells to doxorubicin and x-ray irradiation.

  5. Emi1 expression (>5%) was seen in 23.3% of ovarian clear cell carcinoma, and associated with high FIGO grades and poor overall survival

  6. Emi1 participates in human hepatocellular carcinoma (HCC (zeige FAM126A Antikörper)) cell proliferation and that progression is controlled by anaphase-promoting complex/cyclosome (APC (zeige APC Antikörper)/C) inhibition, which stabilized Skp2 and enabled p27(kip1 (zeige CDKN1B Antikörper)) degradation.

  7. the ability of Emi1 to inhibit APC (zeige APC Antikörper)/C is negatively regulated by CDKs

  8. Results suggest that Bcr-Abl increases Emi1 phosphorylation and stability to prevent Skp2 protein degradation via APC/Cdh1-induced ubiquitination and to enhance proliferation of CML cells.

  9. These data suggest that E2F (zeige E2F1 Antikörper) can activate both transcription of cyclin A (zeige CCNA2 Antikörper) and the hEmi1-dependent stabilization of APC (zeige APC Antikörper)(Cdh1 (zeige CDH1 Antikörper)) targets, such as cyclin A (zeige CCNA2 Antikörper), to promote S phase entry.

  10. Plk1 activates the anaphase promoting complex by directing the SCF-dependent destruction of Emi1 in prophase

Zebrafish F-Box Protein 5 (FBXO5) Interaktionspartner

  1. These data indicate that emi1 deficiency-induced defects in vivo are due to the dysregulation of an APC/C-Cdh1 (zeige CDH1 Antikörper) molecular axis.

  2. harpy/Rca1/emi1 has a role in patterning in the absence of cell division

  3. Emi1 is a critical regulator of genomic fidelity during embryogenesis.

FBXO5 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is similar to xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with FBXO5

  • F-box protein 5 (FBXO5) Antikörper
  • F-box protein 5 (fbxo5) Antikörper
  • F-box only protein 5 (Fbxo5) Antikörper
  • F-box protein 5 (Fbxo5) Antikörper
  • 2510044I10Rik Antikörper
  • ACYPI007854 Antikörper
  • C85305 Antikörper
  • Emi1 Antikörper
  • FBX5 Antikörper
  • Fbxo5 Antikörper
  • Fbxo31 Antikörper
  • fc65h02 Antikörper
  • wu:fc65h02 Antikörper
  • wu:fe06e07 Antikörper
  • wu:fz79f03 Antikörper
  • zgc:136397 Antikörper
  • zgc:158541 Antikörper

Bezeichner auf Proteinebene für FBXO5

F-box only protein 5 , F-box protein Fbx5 , early mitotic inhibitor 1 , f-box only protein 31 , harpy , hrp , rca1

463083 Pan troglodytes
515080 Bos taurus
733555 Xenopus (Silurana) tropicalis
100167030 Acyrthosiphon pisum
26271 Homo sapiens
67141 Mus musculus
292263 Rattus norvegicus
612020 Canis lupus familiaris
445392 Danio rerio
101103731 Ovis aries
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