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p43 (zeige AIMP1 ELISA Kits) induces both the mRNA and protein expression of IP-10 (zeige CXCL10 ELISA Kits).
Data indicate that AIMP1 (zeige AIMP1 ELISA Kits) downregulation using siRNA is a novel tool to restore TGF-beta (zeige TGFB1 ELISA Kits) signaling and thereby increases the chondrogenic potential of dedifferentiated/degenerated chondrocytes.
two homozygous missense variants, p.(Gly299Arg) and p.(Val176Gly), in the gene AIMP1 (zeige AIMP1 ELISA Kits) that co-segregated with the phenotype, are reported.
AIMp1 (zeige AIMP1 ELISA Kits) promotes the proliferation and migration of fibroblasts/endothelial cells and importantly, pro-inflammatory gene expression in monocytes/macrophages and dendritic cells.
AIMP1 (zeige AIMP1 ELISA Kits) appears to function as a novel inhibitor of PPARgamma (zeige PPARG ELISA Kits) that regulates adipocyte differentiation by preventing the transcriptional activation of PPARgamma (zeige PPARG ELISA Kits).
Data indicate that HCV E2 glycoprotein interacts with cellular AIMP1/p43 (zeige AIMP1 ELISA Kits) protein and promotes cell surface expression of membrane glycoproteins gp96 (zeige HSP90B1 ELISA Kits) and transforming growth factor beta TGF-beta signaling.
Data indicate that the N terminus of Pro-EMAP II binds to its C terminus, arginyl-tRNA synthetase (zeige RARS ELISA Kits), and the neurofilament light subunit.
We have determined crystal structures of the coiled-coils from EML2 and EML4, which describe the structural basis of both EML self-association and oncogenic EML4-ALK (zeige ALK ELISA Kits) activation.
EMAP2 is a multifunctional polypeptide with proinflammatory and antiangiogenic activity. (Review)
interactions between the N-terminal domains of ArgRS (zeige RARS ELISA Kits) and AIMP1 (zeige AIMP1 ELISA Kits) are important for the catalytic and noncatalytic activities of ArgRS (zeige RARS ELISA Kits) and for the assembly of the higher-order MSC (zeige MSC ELISA Kits) protein complex with ArgRS (zeige RARS ELISA Kits)-GlnRS (zeige QARS ELISA Kits)-AIMP1 (zeige AIMP1 ELISA Kits)
The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20.
ARS-interacting multifunctional protein 1
, aminoacyl tRNA synthase complex-interacting multifunctional protein 1
, endothelial monocyte-activating polypeptide 2
, endothelial-monocyte activating polypeptide II
, multisynthase complex auxiliary component p43
, multisynthetase complex auxiliary component p43
, small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating)
, echinoderm MT-associated protein (EMAP)-like protein 70
, echinoderm microtubule-associated protein-like 2
, microtubule-associated protein like echinoderm EMAP