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anti-Human SUMO2 Antikörper:
anti-Rat (Rattus) SUMO2 Antikörper:
anti-Mouse (Murine) SUMO2 Antikörper:
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Human Polyclonal SUMO2 Primary Antibody für IHC (p), WB - ABIN388085
Mori, Miki, Tanji, Ogura, Yagihashi, Jensen, Wakabayashi: Incipient intranuclear inclusion body disease in a 78-year-old woman. in Neuropathology : official journal of the Japanese Society of Neuropathology 2011
Show all 6 Pubmed References
Human Monoclonal SUMO2 Primary Antibody für WB - ABIN1882280
Xu, Au: Mapping residues of SUMO precursors essential in differential maturation by SUMO-specific protease, SENP1. in The Biochemical journal 2005
Show all 4 Pubmed References
We further show that the SUMO2 pathway acts independently of exogenous C-MYC (zeige MYC Antikörper) expression and in parallel with small-molecule enhancers of reprogramming. Importantly, suppression of SUMO2 also promotes the generation of human induced pluripotent stem cells .
Increased post-translational modification of proteins by SUMO-2/3 is a cytoprotective response against cell stress induced by ischaemia and reperfusion.
Sumoylation of PML (zeige PML Antikörper) with SUMO2 by UBC9/UBE2I (zeige UBE2I Antikörper) can lead to formation of polymeric SUMO chains. Data suggest that coordination of growing poly-SUMO chain with "back side" binding site on UBC9/UBE2I (zeige UBE2I Antikörper) appears to be required for SUMO chain elongation on PML (zeige PML Antikörper). (PML (zeige PML Antikörper) = promyelocytic leukemia protein (zeige PML Antikörper); SUMO2 = small ubiquitin-like modifier 2; UBC9/UBE2I (zeige UBE2I Antikörper) = ubiquitin-conjugating enzyme (zeige Ube2t Antikörper) UBC9/UBE2I (zeige UBE2I Antikörper))
The data demonstrate that SUMO2 conjugation and SENP3 (zeige ULP1 Antikörper)-driven deSUMOylation of PELP1 (zeige PELP1 Antikörper) is instrumental for ordered progression of ribosome maturation, and they provide molecular insight into the dynamics of ribosome maturation.
This study reveals an essential role of SUMOylated FADD (zeige FADD Antikörper) in Drp1 (zeige CRMP1 Antikörper)- and caspase-10 (zeige CASP10 Antikörper)-dependent necrosis.
This study demonstrated that two polymorphisms of SUMO2 were significantly associated with an increased risk of AD in female group.
FOXP2 (zeige FOXP2 Antikörper) can be modified with all three human SUMO proteins and that PIAS1 (zeige PIAS1 Antikörper) promotes this process.
Hsp27-Ubc9 pathway recognizes the conformation of mutant CFTR which leads to its SUMO-2 conjugation and degradation by the ubiquitin-proteasome system.
Data suggest that RAP80 (zeige UIMC1 Antikörper) SIM (zeige SIM2 Antikörper) (SUMO interacting motif) binds SUMO-2; both specificity and affinity are enhanced through phosphorylation of canonical CK2 (zeige CSNK2A1 Antikörper) (casein kinase 2) site within the SIM (zeige SIM2 Antikörper).
Small ubiquitin-related modifier 2/3 interacts with p65 (zeige GORASP1 Antikörper) and stabilizes it in the cytoplasm in HBV-associated hepatocellular carcinoma.
a regulatory role of ZNF451 (zeige ZNF451 Antikörper)-1 in fine-tuning physiological PML (zeige PML Antikörper) levels
SUMO-2 inhibits aggregation of CPEB3 (zeige CPEB3 Antikörper).
The present study used immunohistochemical and immunoblot analysis with the different developmental stages of mice and demonstrated the developmentally regulated distribution of SUMO2/3 in the brain.
SUMO-2-Tg mouse lines exhibited cardiomyopathy with various severities. SUMO-2 directly regulated apoptosis by at least partially targeting calpain 2 (zeige CAPN2 Antikörper) and calpastatin (zeige CAST Antikörper).
Results indicate that a functional SUMO1 (zeige SUMO1 Antikörper)-3 expression is essential for emotionality and cognition
Expression levels and not functional differences between SUMO2 and SUMO3 (zeige SUMO3 Antikörper) are critical for normal embryogenesis.
Stress-induced phosphorylation of Thr486 in c-Myb (zeige MYB Antikörper) by p38 (zeige CRK Antikörper) mitogen-activated protein kinases attenuates conjugation of SUMO-2/3.
post-ischemic activation of SUMO2/3 conjugation may define the fate of neurons exposed to a transient interruption of blood supply
Alterations in SUMO substrate conjugation may occur and global posttranslational modifications by ubiquitin may play an important role in the mechanisms underlying Alzheimer disease.
activation of SUMO2/3 conjugation is an endogenous neuroprotective stress response.
cyclin E (zeige CCNE1 Antikörper) is dynamically and highly conjugated to SUMO2/3 on chromatin, independently of Cdk2 (zeige CDK2 Antikörper) activity and origin activation.
Functionally similar to human SUMO2 and SUMO3, Arabidopsis SUMO1 and 2 can form chains, even though they do not possess a consensus SUMOylation motif. The surprising finding that plants have dedicated enzymes for chain synthesis implies a specific role for SUMO chains in plants
we provide evidence for the existence of a preferential conjugation of AtSUMO1/2 compared with AtSUMO3/5, which is determined by a role of the E1-activating enzyme in SUMO paralogue discrimination.
SUM3 (zeige SUMO3 Antikörper) promotes plant defense downstream of salicylic acid, while SUM1 (zeige SUMO1 Antikörper) and SUM2 together prevent salicylic acid accumulation in noninfected plants.
SIZ1-mediated conjugation of SUMO1 (zeige SUMO1 Antikörper) and SUMO2 to other intracellular proteins is essential in Arabidopsis, possibly through stress-induced modification of a potentially diverse pool of nuclear proteins.
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
SMT3 homolog 2
, SMT3 suppressor of mif two 3 homolog 2
, sentrin 2
, small ubiquitin-related modifier 2
, ubiquitin-like protein SMT3A
, ubiquitin-like protein SMT3B
, SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)
, SMT3 supressor of mif two 3 homolog 2
, small ubiquitin-related modifier 2-B
, MIF2 suppressor
, Ubiquitin-like protein SMT3B