Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa Proteine (EIF2B1)

Bezeichnung:
Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa Proteine (EIF2B1)
Auf www.antikoerper-online.de finden Sie aktuell 12 Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1) Proteine von 5 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa Antikörper (38) und Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa Kits (3) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 58 Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa Produkte verfügbar.
Synonyme:
26kDa, D5Ertd406e, DDBDRAFT_0219393, DDBDRAFT_0231375, DDB_0219393, DDB_0231375, eIF-2a, EIF2B, EIF2BA
alle Proteine anzeigen Gen GeneID UniProt
EIF2B1 209354 Q99LC8
EIF2B1 64514 Q64270
EIF2B1 1967 Q14232

Weitere Synonyme anzeigen

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Am meisten referenzierte Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa Proteine

  1. Human EIF2B1 Protein expressed in Escherichia coli (E. coli) - ABIN667427 : Mohammad-Qureshi, Haddad, Hemingway, Richardson, Pavitt: Critical contacts between the eukaryotic initiation factor 2B (eIF2B) catalytic domain and both eIF2beta and -2gamma mediate guanine nucleotide exchange. in Molecular and cellular biology 2007 (PubMed)
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Weitere Proteine zu Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa Interaktionspartnern

Mouse (Murine) Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1) Interaktionspartner

  1. These are the first data that mechanistically link eIF2Bepsilon (zeige EIF2B5 Proteine) abundance to skeletal myofibre hypertrophy.

  2. A point mutation in translation initiation factor (zeige TIF1 Proteine) eIF2B (zeige EIF2B4 Proteine) leads to Vanishing White Matter disease.

  3. Inhibition of pancreatic protein synthesis in this model of acute pancreatitis most likely results from inhibition of translation initiation from increased eIF2alpha (zeige EIF2A Proteine) phosphorylation, reduction of eIF2B (zeige EIF2B4 Proteine) activity, and inhibition of eIF4F (zeige EIF4A2 Proteine) complex formation.

Human Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1) Interaktionspartner

  1. Oligodendrocytes with truncated or deletion mutants eIF2B showed less tolerable to endoplasmic reticulum stress

  2. These data emphasize the importance of eIF2Balpha in mediating the eIF2 (zeige EIF2S1 Proteine) kinase translation-inhibitory activity and may provide insight into the complex nature of vesiculovirus oncolysis.

  3. mutational analysis of the eIF2B genes of patients with an antenatal- or early-infantile-onset encephalopathy and an early demise

  4. Biochemical analyses indicate that mutations analyzed in eIF2Balpha and -epsilon reduce the steady-state level of the affected subunit, while the most severe mutant tested, eIF2Bbeta(V341D), forms complexes with reduced stability and lower eIF2B activity.

  5. analysis of novel mutations in patients with eIF2B-related disorders

  6. Study reports 9 novel mutations in EIF2B genes in 8 patients, increasing number of known mutations to more than 120. Using homology modeling, analyzed the impact of novel mutations on the 5 subunits of eIF2B protein (alpha, beta, gamma, delta, epsilon)

  7. The authors suspected VWM and sequenced the genes EIF2B1-5, which revealed one heterozygous mutation in EIF2B4 (zeige EIF2B4 Proteine).

  8. Crystal structure of the alpha subunit (zeige POLG Proteine) of human translation initiation factor (zeige TIF1 Proteine) 2B.

Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1) Protein Überblick

Protein Überblick

This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.

Alternative names and synonyms associated with Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1)

  • translation initiation factor eIF-2B alpha subunit (eIF2b1)
  • translation initiation factor eIF-2B subunit alpha (PGTG_05021)
  • Translation initiation factor eIF-2B subunit alpha (ei2ba)
  • translation initiation factor eif-2b subunit alpha (ei2ba)
  • eukaryotic translation initiation factor 2B, subunit 1 (alpha) (Eif2b1)
  • eukaryotic translation initiation factor 2B, subunit 1 alpha (Eif2b1)
  • eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa (EIF2B1)
  • 26kDa Protein
  • D5Ertd406e Protein
  • DDBDRAFT_0219393 Protein
  • DDBDRAFT_0231375 Protein
  • DDB_0219393 Protein
  • DDB_0231375 Protein
  • eIF-2a Protein
  • EIF2B Protein
  • EIF2BA Protein

Bezeichner auf Proteinebene für EIF2B1

translation initiation factor eIF-2B subunit alpha , Translation initiation factor eIF-2B subunit alpha , translation initiation factor eif-2b subunit alpha , eIF-2B GDP-GTP exchange factor subunit alpha , eukaryotic translation initiation factor 2B, subunit 1 (alpha, 26kDa) , GTP-exchange protein , eIF-2Balpha

GENE ID SPEZIES
8626881 Dictyostelium discoideum AX4
10530886 Puccinia graminis f. sp. tritici CRL 75-36-700-3
100305173 Oncorhynchus mykiss
100528837 Ictalurus punctatus
209354 Mus musculus
64514 Rattus norvegicus
1967 Homo sapiens
516670 Bos taurus
100172592 Pongo abelii
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