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anti-Human YAP1 Antikörper:
anti-Mouse (Murine) YAP1 Antikörper:
anti-Rat (Rattus) YAP1 Antikörper:
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Human Monoclonal YAP1 Primary Antibody für IF, IHC (p) - ABIN564526
Lau, Murray, Houshmandi, Xu, Gutmann, Yu: Merlin is a potent inhibitor of glioma growth. in Cancer research 2008
Show all 17 Pubmed References
Human Polyclonal YAP1 Primary Antibody für ChIP, ICC - ABIN258559
Kapoor, Yao, Ying, Hua, Liewen, Wang, Zhong, Wu, Sadanandam, Hu, Chang, Chu, Al-Khalil, Jiang, Xia, Fletcher-Sananikone, Lim, Horwitz, Viale, Pettazzoni, Sanchez, Wang, Protopopov, Zhang, Heffernan et al.: Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer. ... in Cell 2014
Show all 12 Pubmed References
Human Monoclonal YAP1 Primary Antibody für FACS, IHC - ABIN969574
Fernandez-L, Northcott, Dalton, Fraga, Ellison, Angers, Taylor, Kenney: YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation. in Genes & development 2009
Show all 2 Pubmed References
Dog (Canine) Polyclonal YAP1 Primary Antibody für ELISA, WB - ABIN4219868
Zender, Spector, Xue, Flemming, Cordon-Cardo, Silke, Fan, Luk, Wigler, Hannon, Mu, Lucito, Powers, Lowe: Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach. in Cell 2006
Human Polyclonal YAP1 Primary Antibody für ICC, IF - ABIN4366489
Li, Lim, Chen, McCabe, Kim, Zhang, Mao: Spinal expression of Hippo signaling components YAP and TAZ following peripheral nerve injury in rats. in Brain research 2013
Human Polyclonal YAP1 Primary Antibody für IF (p), IHC (p) - ABIN701485
Li, Shang, Shu, Zhang, Ji, Sun, Li, Xie: gga-miR-375 plays a key role in tumorigenesis post subgroup J avian leukosis virus infection. in PLoS ONE 2014
YAP1 immunohistochemical expression was sharply downregulated in medullary thyroid cancer
YAP1 exerted its effect on the chondrocyte differentiation by activating the Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) signaling pathway
This report describes a novel mutation in YAP1 associated with isolated ocular coloboma in a family with an autosomal dominant pattern of inheritance with apparent incomplete penetrance.
Studies indicate that the transcriptional co-activators YAP and TAZ (zeige TAZ Antikörper) recently emerged as key mediators of the biological effects that are observed in response to extracellular matrix (ECM (zeige MMRN1 Antikörper)) elasticity and cell shape.
The altered mRNA isoform, called MAGI3 (zeige MAGI3 Antikörper)(pPA (zeige PPA1 Antikörper)), produces a truncated protein that acts in a dominant-negative manner to prevent full-length MAGI3 (zeige MAGI3 Antikörper) from interacting with the YAP oncoprotein, thereby relieving YAP inhibition and promoting malignant transformation of human mammary epithelial cells.
Data suggest that high expression of phosphorylated mTOR (zeige FRAP1 Antikörper) (p-mTORS2448) and YAP1 correlates with poor prognosis of glioma patients; potential interaction between mTOR (zeige FRAP1 Antikörper) and YAP1 signaling pathways may participate in development/progression of gliomas. (mTOR (zeige FRAP1 Antikörper) = rapamycin and FKBP12 target 1 protein (zeige FRAP1 Antikörper); YAP1 = Yes-associated protein 1)
Decreased AMOT (zeige AMOT Antikörper)-p130 (zeige RBL2 Antikörper) expression coupled with high nuclear YAP1 expression resulted in shorter overall survival and disease-free survival in patients with advanced gastric cancer.
High Yap expression is associated with breast cancer.
High YAP1 expression is associated with pancreatic cancer.
p53 (zeige TP53 Antikörper) deficiency promotes Yap signaling and that PTPN14 (zeige PTPN14 Antikörper) and TP53 (zeige TP53 Antikörper) mutations are mutually exclusive in human cancers.
P38 MAPK (zeige MAPK14 Antikörper)-mediated YAP activation controls mechanical-tension-induced pulmonary alveolar regeneration.
Nuclear YAP does not play a significant physiological role during oocyte development in mammals.
identify the mesenchymal requirement of YAP/TAZ (zeige TAZ Antikörper) in the gastrointestinal tract and highlight the functional interplays between Hippo and Hedgehog (zeige SHH Antikörper) signaling underlying temporal and spatial control of tissue growth and specification in developing gut (zeige GUSB Antikörper)
findings indicate that HIF-2alpha (zeige EPAS1 Antikörper) increases cancer cell growth by up-regulating YAP1 activity
found that epidermal YAP activity drives GLI2 (zeige GLI2 Antikörper) nuclear accumulation in the skin of YAP2-5SA-DeltaC mice, which depends on epidermal beta-catenin (zeige CTNNB1 Antikörper) activation
Yap and Taz (zeige TAZ Antikörper) leads to impaired epicardial epithelial-to-mesenchymal transition (EMT (zeige ITK Antikörper)) and a reduction in epicardial cell proliferation and differentiation into coronary endothelial cells.
This study identifies YAP/TAZ as central mediators of VEGF signaling
These results suggest that YAP promotes muscle differentiation by activating the Abl (zeige ABL1 Antikörper)/Src (zeige SRC Antikörper)/MEKK3 (zeige MAP3K3 Antikörper)/MEK5 (zeige MAP2K5 Antikörper)/ERK5 (zeige MAPK7 Antikörper) kinase cascade.
data demonstrate that Yap1 is a required factor for proper differentiation of mouse embryonic stem cells, while remaining dispensable for self-renewal
During vascular regression, Yap/Taz is activated by blood circulation in the endothelial cells. This leads to induction of Ctgf and actin polymerization. Interference with Yap/Taz activation decreased Ctgf production, which decreased actin polymerization and vascular regression.
that Yap1 entered the nucleus and promoted transcription in response to blood flow.
that Yap1 integrates the anabolic demands of tissue growth during development and tumorigenesis by reprogramming nitrogen metabolism to stimulate nucleotide biosynthesis
Amotl2a (zeige AMOTL2 Antikörper) function in the control of lateral line primordium cell proliferation is mediated together by the Hippo pathway effector Yap1 and the Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) effector Lef1 (zeige LEF1 Antikörper).
data reveals that Yap is required for pronephric duct integrity, maintenance of baso-lateral cell polarity, and ciliogenesis during zebrafish kidney development
Yap/Taz (zeige TAZ Antikörper)-Tead activity is necessary and sufficient for optic vesicle progenitors to adopt retinal pigment epithelium identity in zebrafish.
Yap is essential for fin regeneration and that its function is dependent on mechanical tension, conferred by a balancing act of cell density and cytoskeleton activity.
When transcriptional coactivators Yap and Taz (zeige TAZ Antikörper) were restricted from interacting with Tead transcription factors through expression of a dominant negative transgene, cardiac precursors failed to migrate completely to the midline.
Yap coordinately regulates cell proliferation and apoptosis and is required for dorsoventral axis formation, gastrulation, cardiogenesis, hematopoiesis, and somitogenesis.
zebrafish yap is required for the development of the brain, eyes, and neural crest during embryogenesis.
Yap1 has a crucial role in controlling the limb regenerative capacity in Xenopus
This gene encodes the human ortholog of chicken YAP protein which binds to the SH3 domain of the Yes proto-oncogene product. This protein contains a WW domain that is found in various structural, regulatory and signaling molecules in yeast, nematode, and mammals, and may be involved in protein-protein interaction.
65 kDa Yes-associated protein
, yes-associated protein 2
, yorkie homolog
, Yes-associated protein 1, 65kDa
, Yes-associated protein 1, 65 kD
, yes-associated protein, 65 kDa