SGK1 Proteine (SGK1)

Bezeichnung:
serum/glucocorticoid Regulated Kinase 1 Proteine (SGK1)
Auf www.antikoerper-online.de finden Sie aktuell 21 serum/glucocorticoid Regulated Kinase 1 (SGK1) Proteine von 10 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SGK1 Antikörper (224) und SGK1 Kits (8) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 271 SGK1 Produkte verfügbar.
Synonyme:
cb1083, sgk, wu:fc20a09
alle Proteine anzeigen Gen GeneID UniProt
SGK1 6446 O00141
SGK1 20393 Q9WVC6
SGK1 29517  

Weitere Synonyme anzeigen

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Am meisten referenzierte SGK1 Proteine

  1. Human SGK1 Protein expressed in Escherichia coli (E. coli) - ABIN667573 : Maiyar, Huang, Phu, Cha, Firestone: p53 stimulates promoter activity of the sgk. serum/glucocorticoid-inducible serine/threonine protein kinase gene in rodent mammary epithelial cells. in The Journal of biological chemistry 1996 (PubMed)
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Weitere Proteine zu SGK1 Interaktionspartnern

Human serum/glucocorticoid Regulated Kinase 1 (SGK1) Interaktionspartner

  1. Findings show that serum and glucocorticoid-inducible kinase 1 (SGK1) protein dynamics can be an important part of intracellular signaling, directly influencing cellular response decisions.

  2. In cancer cells resistant to PI3Kalpha inhibition, PDK1 blockade restores sensitivity to these therapies. SGK1, which is activated by PDK1, contributes to the maintenance of residual mTORC1 activity through direct phosphorylation and inhibition of TSC2.

  3. SGK1 promotes YAP/TAZ transcriptional activity. SGK1 enhances YAP/TAZ activity by upregulating YAP/TAZ. SGK1 is a transcriptional target of YAP. SGK1 stabilizes TAZ by inhibiting GSK3beta.

  4. Potassium supplementation has a blocking effect against salt-loading-induced IL-17A (zeige IL17A Proteine) production in T lymphocytes, and the protective effect was mediated through suppression of p38/MAPK (zeige MAPK14 Proteine)-SGK1 pathway.

  5. Akt3 (zeige AKT3 Proteine) constitutively suppresses macropinocytosis in macrophages through a novel WNK1 (zeige WNK1 Proteine)/SGK1/Cdc42 (zeige CDC42 Proteine) pathway.

  6. Increased expression of SGK1 is associated with Hydrosalpinx.

  7. Human SMCT1 is regulated by insulin (zeige INS Proteine) and SGK1.

  8. SGK1 overexpression in tissues and serum was found in patients with endometriosis.

  9. SGK1 can mediate chemo- and radio-resistance during the treatment of various human tumors, both in vitro and in vivo. (Review)

  10. LEFTY2 (zeige LEFTY2 Proteine) regulates the expression and activity of ENaC (zeige SCNN1A Proteine) in endometrial epithelial cells via SGK1.

Mouse (Murine) serum/glucocorticoid Regulated Kinase 1 (SGK1) Interaktionspartner

  1. our data suggest that renal tubular SGK1 is important in the regulation of K(+) excretion via the control of NEDD4-2 (zeige NEDD4L Proteine), WNK1 (zeige WNK1 Proteine), and ENaC (zeige SCNN1A Proteine)

  2. SGK1 is similarly involved in the regulation of cell volume and cell fluid transport.

  3. Mineralocorticoid receptor (zeige NR3C2 Proteine) deficiency suppresses migration and proliferation of macrophages and leads to less vascular smooth muscle cell activation. At the molecular level, MR deficiency suppresses macrophage inflammatory response via SGK1-AP1 (zeige JUN Proteine)/NF-kappaB (zeige NFKB1 Proteine) pathways.

  4. Akt3 (zeige AKT3 Proteine) constitutively suppresses macropinocytosis in macrophages through a novel WNK1 (zeige WNK1 Proteine)/SGK1/Cdc42 (zeige CDC42 Proteine) pathway.

  5. SGK1 and SGK3 (zeige SGK3 Proteine) are expressed in multiple microglial cell lines. SGK1 and SGK3 (zeige SGK3 Proteine) may play an important role in regulating microglial viability and inflammatory responses.

  6. The data indicate that the balanced activities of two related serine/threonine kinases, AKT (zeige AKT1 Proteine) and SGK1, critically govern the embryo implantation process.

  7. LEFTY2 (zeige LEFTY2 Proteine) regulates the expression and activity of ENaC (zeige SCNN1A Proteine) in endometrial epithelial cells via SGK1.

  8. high levels of resistin (zeige RETN Proteine) observed during obesity may activate SGK1 in the vasculature and contribute to the development of obesity-related vascular disease

  9. High salt diet may deteriorate lupus nephritis through SGK1 pathway.

  10. Study shows that SGK1 impairs nuclear abundance of p27 (zeige CDKN1B Proteine) and suggests that phosphorylation of p27T197 by SGK1 is required for cardiac hypertrophy.

SGK1 Protein Überblick

Protein Überblick

This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Alternative names and synonyms associated with SGK1

  • serum/glucocorticoid regulated kinase 1 (SGK1)
  • serum/glucocorticoid regulated kinase 1 (Sgk1)
  • serum/glucocorticoid regulated kinase 1 (sgk1)
  • cb1083 Protein
  • sgk Protein
  • wu:fc20a09 Protein

Bezeichner auf Proteinebene für SGK1

Sgk1 variant i3 , serine/threonine protein kinase SGK , serine/threonine-protein kinase Sgk1 , serum/glucocorticoid-regulated kinase 1 , serum and glucocorticoid-dependent protein kinase , serum/glucocorticoid regulatory kinase , serum- and glucocorticoid-induced kinase , serum and glucocorticoid-regulated protein kinase

GENE ID SPEZIES
6446 Homo sapiens
20393 Mus musculus
29517 Rattus norvegicus
403647 Canis lupus familiaris
100625739 Sus scrofa
515854 Bos taurus
395133 Gallus gallus
100008723 Oryctolagus cuniculus
324140 Danio rerio
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