RAF1 Proteine (RAF1)

Bezeichnung:
V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 Proteine (RAF1)
Auf www.antikoerper-online.de finden Sie aktuell 27 V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) Proteine von 9 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen RAF1 Antikörper (837) und RAF1 Kits (25) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 930 RAF1 Produkte verfügbar.
Synonyme:
6430402F14Rik, AA990557, Afr-1, Afr1, BB129353, c-Raf, CRAF, Craf1, D830050J10Rik, mKIAA0854, NS5, Raf, Raf-1, RAF1, v-Raf
alle Proteine anzeigen Gen GeneID UniProt
RAF1 5894 P04049
RAF1 110157 Q99N57
RAF1 24703 P11345

Weitere Synonyme anzeigen

RAF1 Proteine (RAF1) nach Spezies

Wählen Sie die gewünschte Spezies

Am meisten referenzierte RAF1 Proteine

  1. Human RAF1 Protein expressed in Wheat germ - ABIN1317314 : Rodríguez-Muñoz, de la Torre-Madrid, Sánchez-Blázquez, Garzón: NO-released zinc supports the simultaneous binding of Raf-1 and PKC? cysteine-rich domains to HINT1 protein at the mu-opioid receptor. in Antioxidants & redox signaling 2011 (PubMed)

Weitere Proteine zu RAF1 Interaktionspartnern

Zebrafish V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) Interaktionspartner

  1. cdk10 (zeige CDK10 Proteine) has roles in vertebrate development and a critical function in neurogenesis by modulation of raf1a expression

  2. Our results indicate that Rb-Raf-1 interaction plays an important role in spontaneous hair cell regeneration in zebrafish

  3. Zebrafish embryos with morpholino knockdown of raf1 demonstrated the need for raf1 for the development of normal myocardial structure and function.

  4. analysis of the roles of Raf- and PI3K-signalling pathways in melanoma

Xenopus laevis V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) Interaktionspartner

  1. Both c-Raf and B-Raf (zeige BRAF Proteine) are required for Ras-induced MEK1 (zeige MAP2K1 Proteine) and p42 (zeige EPB42 Proteine) MAP kinase (zeige MAPK1 Proteine) activation.

Human V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) Interaktionspartner

  1. RhoA (zeige RHOA Proteine)/ROCK and Raf-1/CK2 (zeige CSNK2A1 Proteine) pathway are responsible for TNF-alpha (zeige TNF Proteine)-mediated endothelial cytotoxicity via regulation of the vimentin (zeige VIM Proteine) cytoskeleton.

  2. Although Raf-1 gene is not mutated, an abnormality of Raf-1 kinase feedback regulation enhances its antiapoptotic function, and Raf-1 can still be a pharmaceutical target to increase chemotherapy or radiotherapy sensitivity in these cancer cells.

  3. ZHX2 (zeige ZHX2 Proteine) expression in renal cell carcinoma (zeige MOK Proteine)

  4. RAF1 plays a critical role in maintaining the transformed phenotype of CRC cells, including those with mutated KRAS.

  5. Zhx2 (zeige ZHX2 Proteine) is a novel regulator of Mup expression; Zhx2 (zeige ZHX2 Proteine) activates as well as represses expression of target genes

  6. This finding suggests that stringent assemblage of Hsp90 (zeige HSP90 Proteine) keeps CRAF kinase equipped for participating in the MAPK (zeige MAPK1 Proteine) pathway. Thus, the role of Hsp90 (zeige HSP90 Proteine) in CRAF maturation and activation acts as a limiting factor to maintain the function of a strong client like CRAF kinase.

  7. Oncogenic NFIA:RAF1 fusion activation of the MAPK (zeige MAPK1 Proteine) pathway is associated with pilocytic astrocytoma.

  8. IGF2BP2 (zeige IGF2BP2 Proteine) as a post-transcriptional regulatory mRNA-binding factor, interfering with Raf-1 degradation by miR (zeige MLXIP Proteine)-195, that contributes to Colorectal carcinogenesis.

  9. Data show that when microRNA miR (zeige MLXIP Proteine)-125b was over-expressed in THP-1 macrophages, the expression of Raf1 proto-oncogene (zeige RAB1A Proteine) serine/threonine protein kinase (RAF1) was reduced to promote the apoptosis of macrophages.

  10. Data show that Griffipavixanthone (GPX (zeige GPX1 Proteine)), a dimeric xanthone isolated from Garcinia esculenta, is a B-RAF (zeige SNRPE Proteine) and C-RAF inhibitor against esophageal cancer cells.

Cow (Bovine) V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) Interaktionspartner

  1. data suggest that G alpha(i3), Shc (zeige SHC1 Proteine), Grb2 (zeige GRB2 Proteine), Ras, and Raf-1 link Src (zeige SRC Proteine) to activation of MAPK (zeige MAPK1 Proteine) and to the AT(2)-dependent increase in eNOS (zeige NOS3 Proteine) expression in PAECs

Mouse (Murine) V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) Interaktionspartner

  1. Zhx2 (zeige ZHX2 Proteine) is a novel regulator of Mup expression; Zhx2 (zeige ZHX2 Proteine) activates as well as represses expression of target genes

  2. A- and B-Raf ablation in chondrocytes does not alter skeletal development, whereas ablation of C-Raf decreases hypertrophic chondrocyte apoptosis and impairs vascularization of the growth plate. However, ablation of C-Raf does not impair phosphate-induced ERK1/2 phosphorylation in vitro, but leads to rickets by decreasing VEGF protein stability.

  3. We confirmed that Raf1(L613V) knock-in confers a NS-like phenotype, including cardiac hypertrophy. Active RSK3 (zeige RPS6KA2 Proteine) was increased in Raf1(L613V) mice. Constitutive RSK3 (zeige RPS6KA2 Proteine) gene deletion prevented the Raf1(L613V)-dependent concentric growth in width of the cardiac myocyte and attenuated cardiac hypertrophy in female mice.

  4. C-Raf involves in osteoblast survival in response to mechanical stress.

  5. Dual inhibition of c-Raf and soluble epoxide hydrolase (zeige EPHX2 Proteine) by t-CUPM prevents mutant KrasG12D-initiated murine pancreatic carcinoma growth.

  6. Simultaneous inhibition of sEH (zeige EPHX2 Proteine) and c-RAF prevents chronic pancreatitis and murine pancreatic intraepithelial neoplasia in LSL-KrasG(1)(2)D/Pdx-1 (zeige PDX1 Proteine)-Cre mice.

  7. under normal physiological conditions, PTEN suppresses AKT (zeige AKT1 Proteine) activity to maintain activation of the RAF1/ERK (zeige EPHB2 Proteine) signaling pathway, which in turn maintains normal function of the initial segment and therefore, normal sperm maturation.

  8. these data indicate that B-RAF (zeige SNRPE Proteine) is an important factor in oncogenic C-RAF-mediated tumorigenesis.

  9. PHLPP is a negative regulator of RAF1, which reduces colorectal cancer cell motility and prevents tumor progression in mice.

  10. Raf-MAPK (zeige MAPK1 Proteine)-dependent psoriatic-like epidermal hyperplasia requires Stat3 (zeige STAT3 Proteine) signaling in keratinocytes

RAF1 Protein Überblick

Protein Überblick

The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family.

Alternative names and synonyms associated with RAF1

  • v-raf-1 murine leukemia viral oncogene homolog 1a (raf1a)
  • v-raf-1 murine leukemia viral oncogene homolog 1 (RAF1)
  • v-raf-1 murine leukemia viral oncogene homolog 1 (raf1)
  • v-raf-1 murine leukemia viral oncogene homolog 1 (LOC100341921)
  • v-raf-1 murine leukemia viral oncogene homolog 1 (LOC100347407)
  • raf protein (c-raf)
  • v-raf-leukemia viral oncogene 1 (Raf1)
  • zinc fingers and homeoboxes 2 (ZHX2)
  • zinc fingers and homeoboxes 2 (Zhx2)
  • 6430402F14Rik Protein
  • AA990557 Protein
  • Afr-1 Protein
  • Afr1 Protein
  • BB129353 Protein
  • c-Raf Protein
  • CRAF Protein
  • Craf1 Protein
  • D830050J10Rik Protein
  • mKIAA0854 Protein
  • NS5 Protein
  • Raf Protein
  • Raf-1 Protein
  • RAF1 Protein
  • v-Raf Protein

Bezeichner auf Proteinebene für RAF1

RAF proto-oncogene serine/threonine-protein kinase , murine leukemia viral oncogene homolog , serine/threonine protein kinase RAF1 , v-raf-1 murine leukemia viral oncogene homolog 1 , cRaf , proto-oncogene c-RAF , raf-1 , RAF proto-oncogene serine/threonine-protein kinase-like , Oncogene RAF1 , raf proto-oncogene serine/threonine protein kinase , C-RAF , MIL proto-oncogene serine/threonine-protein kinase , RAF-1 , c-mil protein , murine leukemia viral (v-raf-1) oncogene homolog 1 , Craf1 transforming , murine sarcoma 3611 oncogene 1 , sarcoma 3611 oncogene , v-raf-1 leukemia viral oncogene 1 , murine leukemia viral (v-raf-1) oncogene homolog 1 (3611-MSV) , AFP regulator 1 , alpha-fetoprotein regulator 1 , regulator of AFP , transcription factor ZHX2 , zinc finger and homeodomain protein 2 , zinc fingers and homeoboxes protein 2 , zinc-fingers and homeoboxes 2 , alpha fetoprotein regulation 1, adult

GENE ID SPEZIES
30716 Danio rerio
460182 Pan troglodytes
549871 Xenopus (Silurana) tropicalis
694725 Macaca mulatta
100173732 Pongo abelii
100341921 Oryctolagus cuniculus
100347407 Oryctolagus cuniculus
100415300 Callithrix jacchus
100482255 Ailuropoda melanoleuca
100582599 Nomascus leucogenys
397857 Xenopus laevis
5894 Homo sapiens
396245 Gallus gallus
484648 Canis lupus familiaris
521196 Bos taurus
110157 Mus musculus
24703 Rattus norvegicus
22882 Homo sapiens
387609 Mus musculus
Ausgewählte Anbieter für RAF1 Proteine (RAF1)
Haben Sie etwas anderes gesucht?