MAPK13 Proteine (MAPK13)

Bezeichnung:
Mitogen-Activated Protein Kinase 13 Proteine (MAPK13)
Auf www.antikoerper-online.de finden Sie aktuell 22 Mitogen-Activated Protein Kinase 13 (MAPK13) Proteine von 10 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MAPK13 Antikörper (165) und MAPK13 Kits (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 209 MAPK13 Produkte verfügbar.
Synonyme:
F24B9.3, F24B9_3, MAPK-13, MAPK 13, p38delta, prkm13, sapk4, Serk4
alle Proteine anzeigen Gen GeneID UniProt
MAPK13 5603 O15264
MAPK13 26415 Q9Z1B7
MAPK13 29513  

Weitere Synonyme anzeigen

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Am meisten referenzierte MAPK13 Proteine

  1. Human MAPK13 Protein expressed in Baculovirus infected Insect Cells - ABIN2003341 : Loesch, Chen: The p38 MAPK stress pathway as a tumor suppressor or more? in Frontiers in bioscience : a journal and virtual library 2008 (PubMed)
    Zeige alle 3 Referenzen für 2003341

  2. Human MAPK13 Protein expressed in Baculovirus infected Insect Cells - ABIN2003339 : Knebel, Morrice, Cohen: A novel method to identify protein kinase substrates: eEF2 kinase is phosphorylated and inhibited by SAPK4/p38delta. in The EMBO journal 2001 (PubMed)
    Zeige alle 3 Referenzen für 2003339

  3. Human MAPK13 Protein expressed in Escherichia coli (E. coli) - ABIN667604 : Nishida, Gotoh: The MAP kinase cascade is essential for diverse signal transduction pathways. in Trends in biochemical sciences 1993 (PubMed)
    Zeige alle 2 Referenzen für 667604

Weitere Proteine zu MAPK13 Interaktionspartnern

Arabidopsis thaliana Mitogen-Activated Protein Kinase 13 (MAPK13) Interaktionspartner

  1. AtMKK6-AtMPK13 module positively regulates lateral root formation.[AtMPK13]

Human Mitogen-Activated Protein Kinase 13 (MAPK13) Interaktionspartner

  1. The p38delta mitogen-activated protein kinase (zeige MAPK1 Proteine) was identified as a novel regulator of NLRP3 (zeige NLRP3 Proteine) inflammasome activation in primary human macrophages, and thus, represents a potential target for modulation of atherosclerotic inflammation.

  2. p38delta expression was significantly higher in esophageal squamous cell carcinoma tissues compared with paired normal controls. No significant association was found for p38delta between its expression and other clinicopathological parameters. In Eca109 cells, p38delta can promote the cell growth and motility. p38delta overexpression promotes tumorigenesis in nude mice when p38delta was stably over-expressed and p38ga...

  3. MAPK13 gene knockdown using siRNA reduced the aldehyde dehydrogenase high cell population and abrogated the tumor-initiating ability.

  4. p38gamma and p38delta reprogram liver metabolism by modulating neutrophil infiltration and provide a potential target for NAFLD therapy

  5. MAPK13 undergoes a larger interlobe configurational rearrangement upon activation compared with MAPK14 (zeige MAPK14 Proteine).

  6. PKCdelta (zeige PKCd Proteine) activates a MEKK1 (zeige MAP3K1 Proteine)/MEK3 (zeige MAP2K3 Proteine)/p38delta MAPK (zeige MAPK1 Proteine) cascade to increase p53 (zeige TP53 Proteine) levels and p53 (zeige TP53 Proteine) drives p21(Cip1 (zeige CDKN1A Proteine)) gene expression.

  7. esophageal squamous cell carcinoma cell lines which are p38delta-negative grew more quickly than cell lines which express endogenous p38delta.

  8. DNA methylation alterations are widespread in melanoma; epigenetic silencing of MAPK13 contributes to melanoma progression

  9. Data indicate that p38delta mediates oncogene-induced senescence through a p53- and p16(INK4A)-independent mechanism.

  10. GSK3alpha, GSK3beta, and MAPK13 were found to be the most active tau kinases, phosphorylating tau at all four epitopes.

Mouse (Murine) Mitogen-Activated Protein Kinase 13 (MAPK13) Interaktionspartner

  1. Results reveal that p38delta contributes both cell-autonomous and paracrine effects during the course of skin tumor formation.

  2. p38gamma and p38delta reprogram liver metabolism by modulating neutrophil infiltration and provide a potential target for NAFLD therapy

  3. p38gamma (zeige MAPK12 Proteine) and p38delta control heart growth by modulating mTOR (zeige FRAP1 Proteine) pathway through DEPTOR (zeige DEPTOR Proteine) phosphorylation and subsequent degradation.

  4. Together, our results establish that p38gamma (zeige MAPK12 Proteine) and p38delta are central to colitis-associated colon cancer formation through regulation of hematopoietic cell response to injury, and validate p38gamma (zeige MAPK12 Proteine) and p38kappa as potential targets for cancer therapy.

  5. p38gamma and p38delta are crucial regulators of inflammatory joint destruction in collagen-induced arthritis.

  6. GSK3alpha, GSK3beta, and MAPK13 were found to be the most active tau kinases, phosphorylating tau at all four epitopes.

  7. p27 inhibition of COX-2 expression was specifically due to phosphorylation of transcription factor cAMP response element binding (CREB) phosphorylation mediated by p38beta and p38delta.

  8. Aberrant p38delta-PKD1 (zeige PKD1 Proteine) signaling in neutrophils may underlie development of acute lung injury and life-threatening acute respiratory distress syndrome.

  9. p38gamma (zeige MAPK12 Proteine) and p38delta kinases regulate the Toll-like receptor 4 (TLR4 (zeige TLR4 Proteine))-induced cytokine production by controlling ERK1/2 protein kinase (zeige CDK7 Proteine) pathway activation

  10. results indicate that p38gamma and p38delta have a role in the suppression of tumor development

MAPK13 Protein Überblick

Protein Überblick

This gene encodes a member of the mitogen-activated protein (MAP) kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The encoded protein is a p38 MAP kinase and is activated by proinflammatory cytokines and cellular stress. Substrates of the encoded protein include the transcription factor ATF2 and the microtubule dynamics regulator stathmin. Alternatively spliced transcript variants have been observed for this gene.

Alternative names and synonyms associated with MAPK13

  • mitogen-activated protein kinase 13 (ATMPK13)
  • mitogen-activated protein kinase 13 (MAPK13)
  • mitogen-activated protein kinase 13 (Mapk13)
  • mitogen activated protein kinase 13 (Mapk13)
  • mitogen-activated protein kinase 13 (mapk13)
  • F24B9.3 Protein
  • F24B9_3 Protein
  • MAPK-13 Protein
  • MAPK 13 Protein
  • p38delta Protein
  • prkm13 Protein
  • sapk4 Protein
  • Serk4 Protein

Bezeichner auf Proteinebene für MAPK13

MAP kinase 13 , MAPK 13 , MAP kinase p38 delta , mitogen-activated protein kinase p38 delta , stress-activated protein kinase 4 , SAPK/Erk/kinase 4 , mitogen activated protein kinase 13 , p38 delta MAP kinase , mitogen-activated protein kinase 13

GENE ID SPEZIES
837303 Arabidopsis thaliana
535327 Bos taurus
612821 Canis lupus familiaris
5603 Homo sapiens
26415 Mus musculus
462644 Pan troglodytes
29513 Rattus norvegicus
100144715 Xenopus (Silurana) tropicalis
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