anti-MAP3K5 (MAP3K5) Antikörper

Bezeichnung:
anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 Antikörper (MAP3K5)
Auf www.antikoerper-online.de finden Sie aktuell 389 Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) Antikörper von 29 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MAP3K5 Kits (39) und MAP3K5 Proteine (12) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 467 MAP3K5 Produkte verfügbar.
Synonyme:
7420452D20Rik, ASK, ASK1, MAP3K5, MAPKKK5, MEKK5, mitogen-activated protein kinase kinase kinase 5, MUD21.11, MUD21_11
Alle Antikörper anzeigen Gen GeneID UniProt
MAP3K5 293015 O35099
MAP3K5 4217 Q99683

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Meistgesuchte Reaktivitäten zu anti-MAP3K5 (MAP3K5) Antikörper

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anti-Mouse (Murine) MAP3K5 Antikörper:

anti-Human MAP3K5 Antikörper:

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Am meisten referenzierte anti-MAP3K5 Antikörper

  1. Human Polyclonal MAP3K5 Primary Antibody für WB - ABIN116930 : Matsuzawa, Ichijo: Molecular mechanisms of the decision between life and death: regulation of apoptosis by apoptosis signal-regulating kinase 1. in Journal of biochemistry 2001 (PubMed)
    Zeige alle 14 Referenzen für 116930

  2. Human Monoclonal MAP3K5 Primary Antibody für IF, WB - ABIN393594 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Zeige alle 5 Referenzen für 393594

  3. Human Polyclonal MAP3K5 Primary Antibody für IF, IHC (p) - ABIN197326 : Zhang, Zheng, Storz, Min: Protein kinase D specifically mediates apoptosis signal-regulating kinase 1-JNK signaling induced by H2O2 but not tumor necrosis factor. in The Journal of biological chemistry 2005 (PubMed)
    Zeige alle 4 Referenzen für 197326

  4. Human Polyclonal MAP3K5 Primary Antibody für IHC (p), WB - ABIN196914 : Fujii, Goldman, Park, Zhang, Chen, Fu: Negative control of apoptosis signal-regulating kinase 1 through phosphorylation of Ser-1034. in Oncogene 2004 (PubMed)
    Zeige alle 4 Referenzen für 196914

  5. Human Polyclonal MAP3K5 Primary Antibody für IF, IHC (p) - ABIN197310 : Mabuchi, Ohmichi, Kimura, Nishio, Arimoto-Ishida, Yada-Hashimoto, Tasaka, Murata: Estrogen inhibits paclitaxel-induced apoptosis via the phosphorylation of apoptosis signal-regulating kinase 1 in human ovarian cancer cell lines. in Endocrinology 2003 (PubMed)
    Zeige alle 3 Referenzen für 197310

  6. Human Polyclonal MAP3K5 Primary Antibody für IHC, ELISA - ABIN1531773 : Ichijo, Nishida, Irie, ten Dijke, Saitoh, Moriguchi, Takagi, Matsumoto, Miyazono, Gotoh: Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. in Science (New York, N.Y.) 1997 (PubMed)
    Zeige alle 2 Referenzen für 1531773

  7. Human Polyclonal MAP3K5 Primary Antibody für IHC (p), WB - ABIN196912 : Yuan, Feldman, Sussman, Coppola, Nicosia, Cheng: AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance. in The Journal of biological chemistry 2003 (PubMed)
    Zeige alle 2 Referenzen für 196912

  8. Human Polyclonal MAP3K5 Primary Antibody für IHC, ELISA - ABIN1532802 : Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... in Nature 2003 (PubMed)
    Zeige alle 2 Referenzen für 1532802

  9. Human Polyclonal MAP3K5 Primary Antibody für IF (p), IHC (p) - ABIN683128 : Taniuchi, Furihata, Hanazaki, Iwasaki, Tanaka, Shimizu, Saito, Saibara: Peroxiredoxin 1 Promotes Pancreatic Cancer Cell Invasion by Modulating p38 MAPK Activity. in Pancreas 2015 (PubMed)

Weitere Antikörper gegen MAP3K5 Interaktionspartner

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) Interaktionspartner

  1. These results suggest that the platelet Ask1 plays an important role in regulation of hemostasis and thrombosis.

  2. Lysine 29-linkage of ASK1 by Skp1-Cullin 1-Fbxo21 ubiquitin ligase complex is required for antiviral innate response.

  3. These results demonstrate that trans-fatty acids promote extracellular ATP-induced apoptosis by targeting ASK1 and indicate novel TFA (zeige F3 Antikörper)-associated pathways leading to inflammatory signal transduction and cell death that underlie the pathogenesis and progression of trans-fatty acids-induced atherosclerosis.

  4. Conversely, treatment with LY294002 (a selective inhibitor of Akt1 (zeige AKT1 Antikörper)) reversed the effects of quercetin. In conclusion, these findings highlight the important role of quercetin in protecting against cognitive deficits and inhibiting neuronal apoptosis via the Akt (zeige AKT1 Antikörper) signaling pathway. We believe that quercetin might prove to be a useful therapeutic component in treating cerebral I/R diseases in the near future.

  5. ASK1 MAP kinase (zeige MAPK1 Antikörper) signaling cascade is an important regulator of chondrocyte terminal differentiation.

  6. ASK1 mediates astrocyte activation and leads to glial scar formation after cerebral ischaemia.

  7. ASK1 mediates 3-NP toxicity and regulates C1q level through the astrocyte TGF-beta (zeige TGFB1 Antikörper).

  8. ASK1 signalling regulates brown and beige (zeige LYST Antikörper) adipocyte function.

  9. blocking MPTP (zeige PTPN2 Antikörper)-mediated TNF (zeige TNF Antikörper) signaling through intrathecal administration of TNF (zeige TNF Antikörper)-neutralizing antibody prevented Trx1 (zeige TXN Antikörper) oxidation and downstream ASK1-p38 MAPK (zeige MAPK14 Antikörper) activation

  10. ASK1 deletion in vivo significantly suppresses hyperoxia-induced elevation of inflammatory cytokines (i.e. IL-1beta (zeige IL1B Antikörper) and TNF-alpha (zeige TNF Antikörper)), cell apoptosis in the lung, and recruitment of immune cells

Arabidopsis thaliana Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) Interaktionspartner

  1. PBL27 interacts with both CERK1 and the MAPK (zeige MAPK1 Antikörper) kinase kinase MAPKKK5 at the plasma membrane and knockout of MAPKKK5 compromise chitin-induced MAPK (zeige MAPK1 Antikörper) kinase activation and disease resistance to Alternaria brassicicola.

Human Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) Interaktionspartner

  1. CD40 (zeige CD40 Antikörper) activation resulted in down-regulation of Thioredoxin (Trx)-1 (zeige TXN Antikörper) to permit ASK1 activation and apoptosis. Although soluble receptor (zeige IFNAR1 Antikörper) agonist alone could not induce death, combinatorial treatment incorporating soluble CD40 (zeige CD40 Antikörper) agonist and pharmacological inhibition of Trx-1 (zeige MLL Antikörper) was functionally equivalent to the signal triggered by mCD40L

  2. These results suggest that the platelet Ask1 plays an important role in regulation of hemostasis and thrombosis.

  3. from the two catalytic cysteines of TRX1 (zeige MLL Antikörper) the residue C32 (zeige CKLF Antikörper) is responsible for the high-affinity binding of TRX1 (zeige MLL Antikörper) to the ASK1-TRX (zeige VAC14 Antikörper)-binding domain in reducing conditions

  4. Shotgun mass spectrometry and manual validation identified 12 distinct ASK1 phosphosites. Targeted parallel reaction monitoring assays were used to track the phosphorylation dynamics of each confirmed site in response to treatment.

  5. phosphorus NMR and time-resolved tryptophan fluorescence measurements suggest that 14-3-3zeta (zeige YWHAZ Antikörper) interacts with the kinase domain of ASK1 in close proximity to its active site, thus indicating this interaction might block its accessibility and/or affect its conformation.

  6. ASK1 MAP kinase (zeige MAPK1 Antikörper) signaling cascade is an important regulator of chondrocyte terminal differentiation.

  7. Pretreatment by IRE1 (zeige ERN1 Antikörper) agonist tunicamycin or JNK (zeige MAPK8 Antikörper) agonist anisomycin attenuated the effect of psoralen on osteoporotic osteoblasts. Psoralen inhibited apoptosis of osteoporotic osteoblasts by regulating IRE1 (zeige ERN1 Antikörper)-ASK1-JNK (zeige MAPK8 Antikörper) pathway

  8. Our results thus suggest that GSK-3beta (zeige GSK3b Antikörper) is a key factor involved in ASK1 activation and reactive oxygen species-induced cell death.

  9. the data show that miRNA-mediated down-regulation of ASK1 protects mesenchymal stem cells during post-transplantation, leading to an increase in the efficacy of MSC (zeige MSC Antikörper)-based cell therapy.

  10. Cross-talk between arginine methylation and serine phosphorylation in ASK1.PRMT5 (zeige PRMT5 Antikörper) is an ASK1-binding protein.PRMT5 mediates arginine methylation of ASK1.

MAP3K5 Antigen-Profil

Beschreibung des Gens

Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells\; MAPKKK5 does not activate MAPK/ERK.

Alternative names and synonyms associated with MAP3K5

  • mitogen-activated protein kinase kinase kinase 5 (Map3k5) Antikörper
  • mitogen-activated protein kinase kinase kinase 5 (MAPKKK5) Antikörper
  • mitogen-activated protein kinase kinase kinase 5 (MAP3K5) Antikörper
  • 7420452D20Rik Antikörper
  • ASK Antikörper
  • ASK1 Antikörper
  • MAP3K5 Antikörper
  • MAPKKK5 Antikörper
  • MEKK5 Antikörper
  • mitogen-activated protein kinase kinase kinase 5 Antikörper
  • MUD21.11 Antikörper
  • MUD21_11 Antikörper

Bezeichner auf Proteinebene für MAP3K5

ASK-1 , MAPK/ERK kinase kinase 5 , MEK kinase 5 , MEKK 5 , apoptosis signal-regulating kinase 1 , mitogen activated protein kinase kinase kinase 5 , MAP/ERK kinase kinase 5 , apoptosis signal regulating kinase 1 , mitogen-activated protein kinase kinase kinase 5

GENE ID SPEZIES
293015 Mus musculus
836819 Arabidopsis thaliana
4217 Homo sapiens
26408 Mus musculus
100157454 Sus scrofa
537380 Bos taurus
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