Mitogen-Activated Protein Kinase Kinase Kinase 3 ELISA Kits (MAP3K3)
Auf finden Sie aktuell 0 Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) ELISA Kits von unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MAP3K3 Antikörper (62) und MAP3K3 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 81 MAP3K3 Produkte verfügbar.
AW548911, MAPKKK3, Mekk3, mKIAA4031
list all ELISA KIts Gen GeneID UniProt
Ratte MAP3K3 MAP3K3 303604  
Human MAP3K3 MAP3K3 4215 Q99759
Maus MAP3K3 MAP3K3 26406 Q61084

Weitere Synonyme anzeigen

Weitere ELISA Kits für MAP3K3 Interaktionspartner

Human Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) Interaktionspartner

  1. All these suggest that the MAP3K M1P site is a potential interacting partner of MAP3K SH3 domain (zeige ITSN1 ELISA Kits), which may mediate the intermolecular recognition between hPTTG1 and MAP3K.

  2. Polymorphisms in MAP3K3, MMP24 (zeige MMP24 ELISA Kits) and IGF1R (zeige IGF1R ELISA Kits) are associated with greater height and act additively on height in children of an admixed population.

  3. MAP3K3 overexpression is an independent poor prognostic indicator in ovarian carcinoma.

  4. MAP3K3 may potentially not only serve as diagnostic/prognostic markers for patients with lung cancer but also provide an indicator for future investigations into immunomodulatory therapies for lung cancer.

  5. studies identify gain of MEKK3 signallin (zeige KLF2 ELISA Kits)g and KL (zeige KLF4 ELISA Kits)F2/4 function as causal mechanisms for cerebral cavernous malformations pathogenesis that may be targeted to develop new CCM therapeutics

  6. High MEKK3 expression is associated with renal clear cell carcinoma.

  7. MEKK3 expression was significantly higher in patients with renal clear cell carcinoma than in controls.

  8. This (zeige NBR1 ELISA Kits) study identified an NBR1-MEKK3 complex as a key regulator of JNK s (zeige NBR1 ELISA Kits)ignaling and adipose tissue inflam (zeige MAPK8 ELISA Kits)mation in obesity.

  9. Our finding that Verrucous venous malformation contains a MAP3K3 mutation supports our impression that this lesion is a venous anomaly.

  10. MEKK3 expression was positively correlated with survivin (zeige BIRC5 ELISA Kits).

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) Interaktionspartner

  1. this study shows that TAK1 (zeige NR2C2 ELISA Kits) negatively regulates lipopolysaccharide-induced cytokine secretion in myeloid cells by inhibiting MEKK3 activities

  2. endothelial-specific loss of Mekk3, Klf2 (zeige KLF2 ELISA Kits) or Klf4 (zeige KLF4 ELISA Kits) markedly prevents cerebral cavernous malformation lesion formation, reverses the increase in Rho activity, and rescues lethality

  3. CCM2 (zeige CCM2 ELISA Kits):MEKK3-mediated regulation of Rho-ROCK signalling is required for maintenance of neurovascular integrity, a mechanism by which CCM2 (zeige CCM2 ELISA Kits) loss leads to disease.

  4. NBR1 (zeige NBR1 ELISA Kits) is increased in adipose tissue macrophages in obese mice. The NBR1 (zeige NBR1 ELISA Kits)-MEKK3 complex is important in JNK (zeige MAPK8 ELISA Kits) activation in macrophages.

  5. MEKK2 (zeige MAP3K2 ELISA Kits) alone can suppress T-cell TGF-beta (zeige TGFB1 ELISA Kits) responses. MEKK2 (zeige MAP3K2 ELISA Kits) or MEKK3 can cause ERK1/2 (zeige MAPK1/3 ELISA Kits) to phosphorylate SMAD2 (zeige SMAD2 ELISA Kits)/3 and suppress R-SMAD (zeige SMAD1 ELISA Kits)-dependent transcription. MEKK2 (zeige MAP3K2 ELISA Kits) and MEKK3 play overlapping roles in regulating Th-cell differentiation via TGF-beta (zeige TGFB1 ELISA Kits)

  6. Using Mekk3-deficient murine T cells, the authors concluded MEKK3 expression is required for mounting optimal T cell responses in vivo and is involved in mediating the TCR-dependent Rac1/2 signals for IFN-gamma (zeige IFNG ELISA Kits) production through the MAPK (zeige MAPK1 ELISA Kits) pathways.

  7. The signaling defect of elevated interleukin (IL)-12 (zeige IL12A ELISA Kits) overproducing cells in nonobese diabetic mice could be attributed to, at least partially, the overexpression of a single MAP3K, namely MEKK3.

  8. Strikingly, chimeric mice transplanted with Mekk3(Deltaflox/-) BM exhibited a reduction in tumor growth and vessel density compared with mice transplanted with Mekk3(Deltaflox/+) BM cells.

  9. PB1 domain mediates the association of MEKK2 (zeige MAP3K2 ELISA Kits) and MEKK3 with MEK5 (zeige MAP2K5 ELISA Kits) and that the respective PB1 domains of these kinases are critical for regulation of the ERK5 (zeige MAPK7 ELISA Kits) pathway.

  10. Results show that MEKK3 is essential in the rapid activation of NF-kappaB (zeige NFKB1 ELISA Kits), whereas MEKK2 (zeige MAP3K2 ELISA Kits) is important in controlling the delayed activation of NF-kappaB (zeige NFKB1 ELISA Kits) in response to stimulation with the cytokines TNF-alpha (zeige TNF ELISA Kits) and IL-1alpha.

MAP3K3 Antigen-Profil

Beschreibung des Gens

This gene product is a 626-amino acid polypeptide that is 96.5% identical to mouse Mekk3. Its catalytic domain is closely related to those of several other kinases, including mouse Mekk2, tobacco NPK, and yeast Ste11. Northern blot analysis revealed a 4.6-kb transcript that appears to be ubiquitously expressed. This protein directly regulates the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by activating SEK and MEK1/2 respectively\; it does not regulate the p38 pathway. In cotransfection assays, it enhanced transcription from a nuclear factor kappa-B (NFKB)-dependent reporter gene, consistent with a role in the SAPK pathway. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Alternative names and synonyms associated with MAP3K3

  • mitogen activated protein kinase kinase kinase 3 (Map3k3) Elisa Kit
  • mitogen-activated protein kinase kinase kinase 3 (MAP3K3) Elisa Kit
  • mitogen-activated protein kinase kinase kinase 3 (Map3k3) Elisa Kit
  • mitogen-activated protein kinase kinase kinase 3 (map3k3) Elisa Kit
  • AW548911 Elisa Kit
  • MAPKKK3 Elisa Kit
  • Mekk3 Elisa Kit
  • mKIAA4031 Elisa Kit

Bezeichner auf Proteinebene für MAP3K3

mitogen-activated protein kinase kinase kinase 3 , MAP/ERK kinase kinase 3 , MAPK/ERK kinase kinase 3 , MEK kinase 3 , MEKK 3 , mitogen activated protein kinase kinase kinase 3

303604 Rattus norvegicus
4215 Homo sapiens
26406 Mus musculus
560211 Danio rerio
Haben Sie etwas anderes gesucht?