MAP3K11 (MAP3K11) ELISA Kits

Bezeichnung:
Mitogen-Activated Protein Kinase Kinase Kinase 11 ELISA Kits (MAP3K11)
Auf www.antikoerper-online.de finden Sie aktuell 0 Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11) ELISA Kits von unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MAP3K11 Antikörper (60) und MAP3K11 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 71 MAP3K11 Produkte verfügbar.
Synonyme:
2610017K16Rik, MEKK11, Mlk-3, Mlk3, PTK1, RHOE, SPRK
list all ELISA KIts Gen GeneID UniProt
Human MAP3K11 MAP3K11 4296 Q16584
Maus MAP3K11 MAP3K11 26403 Q80XI6
Ratte MAP3K11 MAP3K11 309168 Q66HA1

Weitere Synonyme anzeigen

Weitere ELISA Kits für MAP3K11 Interaktionspartner

Human Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11) Interaktionspartner

  1. Data indicate that BTG2 (zeige BTG2 ELISA Kits), MAP3K11, RPS6KA1 (zeige RPS6KA1 ELISA Kits) and PRDM1 (zeige PRDM1 ELISA Kits) as putative targets of microRNA miR (zeige MLXIP ELISA Kits)-125b.

  2. Increased expression of MAP3K11 is associated with esophageal cancer.

  3. During hepatocyte lipotoxicity, activated MLK3 induces the release of CXCL10 (zeige CXCL10 ELISA Kits)-bearing vesicles from hepatocytes, which are chemotactic for macrophages.

  4. MLK3 serves as a common upstream kinase of AMPK (zeige PRKAA1 ELISA Kits) and JNK (zeige MAPK8 ELISA Kits) and functions as a direct upstream kinase for AMPK (zeige PRKAA1 ELISA Kits) independent of LKB1 (zeige STK11 ELISA Kits)

  5. MLK3 represents a newly recognized integral component of HER2 (zeige ERBB2 ELISA Kits) biology in HER2 (zeige ERBB2 ELISA Kits)+ breast tumors.

  6. MLK3 is a critical factor controlling the activity of kinase networks that control the cellular responses to different concentrations of reactive oxygen species.

  7. Signaling pathways associated with the Pro252His mutation in MLK3 are located in the kinase domain which is an important domain for the regulation of downstream signaling pathways.

  8. CHIP modulates MLK3 protein levels in response to Geldanamycin and stress stimuli, and CHIP-dependent regulation of MLK3 is required for suppression of SKOV3 ovarian cancer cell invasion.

  9. Data indicate URMC-099 as an orally bioavailable, potent mixed lineage kinase 3 MLK3 inhibitor.

  10. CTGF acting through Rac1 activates the MLK3/JNK signaling pathway, which in turn initiates AP-1 activation and recruitment of c-Jun and c-Fos to the collagen I promoter and ultimately induces collagen I expression in human lung fibroblasts

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11) Interaktionspartner

  1. MAP3K11 might function as an important tumor suppressor neutralized by oncomiR-125b in B-cell leukemia.

  2. During hepatocyte lipotoxicity, activated MLK3 (zeige KCNK7 ELISA Kits) induces the release of CXCL10 (zeige CXCL10 ELISA Kits)-bearing vesicles from hepatocytes, which are chemotactic for macrophages.

  3. TRB3 (zeige TRIB3 ELISA Kits)(-/-) islets show a decrease in both the amplitude and duration of cytokine-stimulated MLK3 (zeige KCNK7 ELISA Kits) induction and JNK (zeige MAPK8 ELISA Kits) activation.

  4. MLK3 (zeige KCNK7 ELISA Kits) limits RhoA (zeige RHOA ELISA Kits) activation and injury-induced neointima formation by binding to and inhibiting the activation of p63Rho guanine nucleotide exchange factor (zeige ARHGEF12 ELISA Kits), a RhoA (zeige RHOA ELISA Kits) activator.

  5. Genetic or pharmacologic inhibition of MLK3 (zeige KCNK7 ELISA Kits) blocks fMLP (zeige FPR1 ELISA Kits)-mediated motility of neutrophils both in vitro and in vivo, suggesting that MLK3 (zeige KCNK7 ELISA Kits) may be a therapeutic target in human diseases characterized by exuberant neutrophil migration.

  6. Data indicate URMC-099 as an orally bioavailable, potent mixed lineage kinase 3 MLK3 inhibitor.

  7. Data from knockout mice suggest that MLK3 (zeige KCNK7 ELISA Kits) plays role in saturated fatty acid-induced activation of MAP kinase (zeige MAPK1 ELISA Kits) signaling; MLK3 (zeige KCNK7 ELISA Kits) appears to be involved in pathogenesis of obesity, adipose tissue in fl ammation, insulin (zeige INS ELISA Kits) resistance, and fatty liver disease.

  8. Lysine 63-linked ubiquitination modulates mixed lineage kinase-3 interaction with JIP1 (zeige MAPK8IP1 ELISA Kits) scaffold protein (zeige HOMER1 ELISA Kits) in cytokine-induced pancreatic beta cell death

  9. These results reveal a novel role for MLK3 (zeige KCNK7 ELISA Kits) signaling in the regulation of intestinal epithelial migration in vivo and suggest that MLK3 (zeige KCNK7 ELISA Kits) may be an important target for the regulation of intestinal mucosal healing.

  10. mice with a targeted deletion of Mlk3 (zeige KCNK7 ELISA Kits) displayed multiple skeletal defects, including dental abnormalities, deficient calvarial mineralization, and reduced bone mass

MAP3K11 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.

Alternative names and synonyms associated with MAP3K11

  • mitogen-activated protein kinase kinase kinase 11 (MAP3K11) Elisa Kit
  • mitogen-activated protein kinase kinase kinase 11 (Map3k11) Elisa Kit
  • 2610017K16Rik Elisa Kit
  • MEKK11 Elisa Kit
  • Mlk-3 Elisa Kit
  • Mlk3 Elisa Kit
  • PTK1 Elisa Kit
  • RHOE Elisa Kit
  • SPRK Elisa Kit

Bezeichner auf Proteinebene für MAP3K11

SH3 domain-containing proline-rich kinase , mixed lineage kinase 3 , protein-tyrosine kinase PTK1 , src-homology 3 domain-containing proline-rich kinase , mitogen activated protein kinase kinase kinase 11

GENE ID SPEZIES
4296 Homo sapiens
26403 Mus musculus
309168 Rattus norvegicus
483732 Canis lupus familiaris
514210 Bos taurus
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