anti-MAP3K11 (MAP3K11) Antikörper

Bezeichnung:
anti-Mitogen-Activated Protein Kinase Kinase Kinase 11 Antikörper (MAP3K11)
Auf www.antikoerper-online.de finden Sie aktuell 60 Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11) Antikörper von 17 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MAP3K11 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 71 MAP3K11 Produkte verfügbar.
Synonyme:
2610017K16Rik, MEKK11, Mlk-3, Mlk3, PTK1, RHOE, SPRK

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anti-Human MAP3K11 Antikörper:

anti-Mouse (Murine) MAP3K11 Antikörper:

anti-Rat (Rattus) MAP3K11 Antikörper:

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Am meisten referenzierte anti-MAP3K11 Antikörper

  1. Human Monoclonal MAP3K11 Primary Antibody für WB - ABIN659128 : Chen, Miller, Gallo: MLK3 is critical for breast cancer cell migration and promotes a malignant phenotype in mammary epithelial cells. in Oncogene 2010 (PubMed)
    Zeige alle 3 Referenzen für 659128

  2. Human Polyclonal MAP3K11 Primary Antibody für WB - ABIN651367 : Rangasamy, Mishra, Mehrotra, Sondarva, Ray, Rao, Chatterjee, Rana, Rana: Estrogen suppresses MLK3-mediated apoptosis sensitivity in ER+ breast cancer cells. in Cancer research 2010 (PubMed)
    Zeige alle 3 Referenzen für 651367

  3. Cow (Bovine) Polyclonal MAP3K11 Primary Antibody für WB - ABIN2786655 : Muniyappa, Das: Activation of c-Jun N-terminal kinase (JNK) by widely used specific p38 MAPK inhibitors SB202190 and SB203580: a MLK-3-MKK7-dependent mechanism. in Cellular signalling 2008 (PubMed)

  4. Human Polyclonal MAP3K11 Primary Antibody für WB - ABIN4334888 : Chien, Lin, Wang, Lee, Chen, Fong, Shih: Acacetin inhibits the invasion and migration of human non-small cell lung cancer A549 cells by suppressing the p38α MAPK signaling pathway. in Molecular and cellular biochemistry 2011 (PubMed)

  5. Human Polyclonal MAP3K11 Primary Antibody für IHC, ELISA - ABIN1533179 : Ing, Leung, Heng, Tsui, Lassam: MLK-3: identification of a widely-expressed protein kinase bearing an SH3 domain and a leucine zipper-basic region domain. in Oncogene 1994 (PubMed)

Weitere Antikörper gegen MAP3K11 Interaktionspartner

Human Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11) Interaktionspartner

  1. Data indicate that BTG2 (zeige BTG2 Antikörper), MAP3K11, RPS6KA1 (zeige RPS6KA1 Antikörper) and PRDM1 (zeige PRDM1 Antikörper) as putative targets of microRNA miR (zeige MLXIP Antikörper)-125b.

  2. Increased expression of MAP3K11 is associated with esophageal cancer.

  3. During hepatocyte lipotoxicity, activated MLK3 induces the release of CXCL10 (zeige CXCL10 Antikörper)-bearing vesicles from hepatocytes, which are chemotactic for macrophages.

  4. MLK3 serves as a common upstream kinase of AMPK (zeige PRKAA1 Antikörper) and JNK (zeige MAPK8 Antikörper) and functions as a direct upstream kinase for AMPK (zeige PRKAA1 Antikörper) independent of LKB1 (zeige STK11 Antikörper)

  5. MLK3 represents a newly recognized integral component of HER2 (zeige ERBB2 Antikörper) biology in HER2 (zeige ERBB2 Antikörper)+ breast tumors.

  6. MLK3 is a critical factor controlling the activity of kinase networks that control the cellular responses to different concentrations of reactive oxygen species.

  7. Signaling pathways associated with the Pro252His mutation in MLK3 are located in the kinase domain which is an important domain for the regulation of downstream signaling pathways.

  8. CHIP modulates MLK3 protein levels in response to Geldanamycin and stress stimuli, and CHIP-dependent regulation of MLK3 is required for suppression of SKOV3 ovarian cancer cell invasion.

  9. Data indicate URMC-099 as an orally bioavailable, potent mixed lineage kinase 3 MLK3 inhibitor.

  10. CTGF acting through Rac1 activates the MLK3/JNK signaling pathway, which in turn initiates AP-1 activation and recruitment of c-Jun and c-Fos to the collagen I promoter and ultimately induces collagen I expression in human lung fibroblasts

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11) Interaktionspartner

  1. MAP3K11 might function as an important tumor suppressor neutralized by oncomiR-125b in B-cell leukemia.

  2. During hepatocyte lipotoxicity, activated MLK3 (zeige KCNK7 Antikörper) induces the release of CXCL10 (zeige CXCL10 Antikörper)-bearing vesicles from hepatocytes, which are chemotactic for macrophages.

  3. TRB3 (zeige TRIB3 Antikörper)(-/-) islets show a decrease in both the amplitude and duration of cytokine-stimulated MLK3 (zeige KCNK7 Antikörper) induction and JNK (zeige MAPK8 Antikörper) activation.

  4. MLK3 (zeige KCNK7 Antikörper) limits RhoA (zeige RHOA Antikörper) activation and injury-induced neointima formation by binding to and inhibiting the activation of p63Rho guanine nucleotide exchange factor (zeige ARHGEF12 Antikörper), a RhoA (zeige RHOA Antikörper) activator.

  5. Genetic or pharmacologic inhibition of MLK3 (zeige KCNK7 Antikörper) blocks fMLP (zeige FPR1 Antikörper)-mediated motility of neutrophils both in vitro and in vivo, suggesting that MLK3 (zeige KCNK7 Antikörper) may be a therapeutic target in human diseases characterized by exuberant neutrophil migration.

  6. Data indicate URMC-099 as an orally bioavailable, potent mixed lineage kinase 3 MLK3 inhibitor.

  7. Data from knockout mice suggest that MLK3 (zeige KCNK7 Antikörper) plays role in saturated fatty acid-induced activation of MAP kinase (zeige MAPK1 Antikörper) signaling; MLK3 (zeige KCNK7 Antikörper) appears to be involved in pathogenesis of obesity, adipose tissue in fl ammation, insulin (zeige INS Antikörper) resistance, and fatty liver disease.

  8. Lysine 63-linked ubiquitination modulates mixed lineage kinase-3 interaction with JIP1 (zeige MAPK8IP1 Antikörper) scaffold protein (zeige HOMER1 Antikörper) in cytokine-induced pancreatic beta cell death

  9. These results reveal a novel role for MLK3 (zeige KCNK7 Antikörper) signaling in the regulation of intestinal epithelial migration in vivo and suggest that MLK3 (zeige KCNK7 Antikörper) may be an important target for the regulation of intestinal mucosal healing.

  10. mice with a targeted deletion of Mlk3 (zeige KCNK7 Antikörper) displayed multiple skeletal defects, including dental abnormalities, deficient calvarial mineralization, and reduced bone mass

MAP3K11 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.

Alternative names and synonyms associated with MAP3K11

  • mitogen-activated protein kinase kinase kinase 11 (MAP3K11) Antikörper
  • mitogen-activated protein kinase kinase kinase 11 (Map3k11) Antikörper
  • 2610017K16Rik Antikörper
  • MEKK11 Antikörper
  • Mlk-3 Antikörper
  • Mlk3 Antikörper
  • PTK1 Antikörper
  • RHOE Antikörper
  • SPRK Antikörper

Bezeichner auf Proteinebene für MAP3K11

SH3 domain-containing proline-rich kinase , mixed lineage kinase 3 , protein-tyrosine kinase PTK1 , src-homology 3 domain-containing proline-rich kinase , mitogen activated protein kinase kinase kinase 11

GENE ID SPEZIES
4296 Homo sapiens
26403 Mus musculus
309168 Rattus norvegicus
483732 Canis lupus familiaris
514210 Bos taurus
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