anti-MAP2K4 (MAP2K4) Antikörper

Bezeichnung:
anti-Mitogen-Activated Protein Kinase Kinase 4 Antikörper (MAP2K4)
Auf www.antikoerper-online.de finden Sie aktuell 327 Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) Antikörper von 29 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MAP2K4 Proteine (11) und MAP2K4 Kits (8) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 365 MAP2K4 Produkte verfügbar.
Synonyme:
2, 142758_at, ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4, ATMEK4, ATMKK4, CG9738, CT27508, CT38386, D-MKK4, DmelCG12798, Dmel\\CG9738, dMkk4, F19C24.26, F19C24_26, hep, JNKK, JNKK1, Jnkk2, map2k4, MAP KINASE KINASE 4, MAPKK4, Mapkk7, MEK4, Mek7, mitogen-activated protein kinase kinase 4, MKK4, MKK4A-l, Mkk7, Mpk4, PRKMK4, SAPKK-1, SAPKK1, SEK1, SEK1/MKK4, Serk1, SKK1, xmek2, zgc:136500
Alle Antikörper anzeigen Gen GeneID UniProt
MAP2K4 287398  
MAP2K4 6416 P45985
MAP2K4 26398 P47809

Alle Spezies anzeigen

Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-MAP2K4 (MAP2K4) Antikörper

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anti-Rat (Rattus) MAP2K4 Antikörper:

anti-Human MAP2K4 Antikörper:

anti-Mouse (Murine) MAP2K4 Antikörper:

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Am meisten referenzierte anti-MAP2K4 Antikörper

  1. Human Polyclonal MAP2K4 Primary Antibody für IHC, ELISA - ABIN1531968 : Lin, Minden, Martinetto, Claret, Lange-Carter, Mercurio, Johnson, Karin: Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2. in Science (New York, N.Y.) 1995 (PubMed)
    Zeige alle 2 Referenzen für 1531968

  2. Human Polyclonal MAP2K4 Primary Antibody für IF, IHC (p) - ABIN197322 : Wang, Chen, Liao, Deng, Zhou, Huang, Sun: Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence. in Molecular and cellular biology 2002 (PubMed)
    Zeige alle 2 Referenzen für 197322

  3. Human Monoclonal MAP2K4 Primary Antibody für FACS, IHC - ABIN969268 : Song, Coffa, Fu, Gurevich: How does arrestin assemble MAPKs into a signaling complex? in The Journal of biological chemistry 2008 (PubMed)
    Zeige alle 2 Referenzen für 969268

  4. Human Polyclonal MAP2K4 Primary Antibody für IHC (p), WB - ABIN658838 : Finegan, Tournier: The mitogen-activated protein kinase kinase 4 has a pro-oncogenic role in skin cancer. in Cancer research 2010 (PubMed)
    Zeige alle 2 Referenzen für 658838

  5. Human Polyclonal MAP2K4 Primary Antibody für ELISA, WB - ABIN1533737 : Dérijard, Raingeaud, Barrett, Wu, Han, Ulevitch, Davis: Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms. in Science (New York, N.Y.) 1995 (PubMed)
    Zeige alle 2 Referenzen für 1533737

  6. Human Polyclonal MAP2K4 Primary Antibody für IF, IHC (p) - ABIN196908 : Leung, Lassam: The kinase activation loop is the key to mixed lineage kinase-3 activation via both autophosphorylation and hematopoietic progenitor kinase 1 phosphorylation. in The Journal of biological chemistry 2001 (PubMed)
    Zeige alle 2 Referenzen für 196908

  7. Human Polyclonal MAP2K4 Primary Antibody für IF, IHC (p) - ABIN196910 : Park, Kim, Huh, Park, Chung, Kang, Choi: Akt (protein kinase B) negatively regulates SEK1 by means of protein phosphorylation. in The Journal of biological chemistry 2002 (PubMed)

Weitere Antikörper gegen MAP2K4 Interaktionspartner

Fruit Fly (Drosophila melanogaster) Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) Interaktionspartner

  1. in Drosophila both MAPKKs, Hep/Mkk7 (zeige MAP2K7 Antikörper) and Mkk4, are required to induce JNK (zeige MAPK8 Antikörper) upon TNF (zeige TNF Antikörper) or pro-inflammatory stimulation

Human Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) Interaktionspartner

  1. MKK4 activates non-canonical NFkappaB (zeige NFKB1 Antikörper) signaling by promoting NFkappaB2-p100 (zeige CUX1 Antikörper) processing.

  2. Manipulating the expression of both miR (zeige MLXIP Antikörper)-222 and miR (zeige MLXIP Antikörper)-25 influenced diverse gene expression changes in thyroid cells. Increased expression of miR (zeige MLXIP Antikörper)-25 reduced MEK4 and TRAIL protein expression, and cell adhesion and apoptosis are important aspects of miR (zeige MLXIP Antikörper)-25 functioning in thyroid cells.

  3. These results suggest that ROCK may be important in IL-1 (zeige IL1A Antikörper)-induced signaling through MKK4 to JNK (zeige MAPK8 Antikörper) and the activation of p38 MAPK (zeige MAPK14 Antikörper).

  4. Association between MKK4 promoter polymorphism and breast cancer risk in Kashmiri population

  5. In Chinese Han ischemic stroke patients rs3826392 C/A genotype carriers showed significantly higher IL-1b (zeige IL1B Antikörper) serum levels.

  6. The plasma level of protein MAP2K4 was found to suggestively associate negatively with the volume of the left entorhinal cortex in asymptomatic older twins.

  7. MAP2K4 increases human prostate cancer metastasis, and prolonged over expression induces long term changes in cell signaling pathways leading to independence from p38 MAPK (zeige MAPK14 Antikörper) and JNK (zeige MAPK8 Antikörper).

  8. MKK4 is activated in vitro by reduced Trx (zeige VAC14 Antikörper) but not oxidized Trx (zeige VAC14 Antikörper) in the absence of an upstream kinase, suggesting that autophosphorylation of this protein occurs due to reduction of Cys (zeige DNAJC5 Antikörper)-246 and Cys (zeige DNAJC5 Antikörper)-266 by Trx (zeige VAC14 Antikörper).

  9. Data suggest a genetic interaction between MAP2K4 and HLA-DRB1 (zeige HLA-DRB1 Antikörper), and the importance of rs10468473 and MAP2K4 splice variants in the development of autoantibody-positive RA.

  10. knockdown of Sec8 (zeige EXOC4 Antikörper) enhances the binding of JIP4 (zeige SPAG9 Antikörper) to MAPK (zeige MAPK1 Antikörper) kinase 4, thereby decreasing the phosphorylation of MAPK (zeige MAPK1 Antikörper) kinase 4, JNK (zeige MAPK8 Antikörper), and p38 (zeige CRK Antikörper).

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) Interaktionspartner

  1. MKK4 activates non-canonical NFkappaB signaling by promoting NFkappaB2-p100 (zeige PATL2 Antikörper) processing.

  2. Demonstrate that Mkk4 is a negative regulator of the TGF-beta1 (zeige TGFB1 Antikörper) signaling associated with atrial remodeling and arrhythmogenesis with age.

  3. This study provides compelling evidence for the pivotal roles of the ZPK/DLK (zeige MAP3K12 Antikörper) and MKK4/MAP2K4-dependent mechanism in axotomy-induced motoneuron death in neonates.

  4. The loss of mkk4 and mkk7 (zeige MAP2K7 Antikörper) locks damaged exocrine cells in a permanently de-differentiated state.

  5. Studies identify the dual-specific kinase MKK4 as a master regulator of liver regeneration. MKK4 silencing robustly increased the regenerative capacity of hepatocytes in mouse models of liver regeneration and acute and chronic liver failure.

  6. MicroRNA-92a negatively regulates Toll (zeige TLR4 Antikörper)-like receptor (TLR)-triggered inflammatory response in macrophages by targeting MKK4 kinase

  7. Distinct signaling properties of mitogen-activated protein kinase kinases 4 (MKK4) and 7 (MKK7) in embryonic stem cell (ESC) differentiation.

  8. MKK4/7 and JNK1 (zeige MAPK8 Antikörper)/2 played regulatory role in cytoskeleton reorganization during vaccinia virus infection.

  9. These data support a model in which MKK4 activation at the metastatic site causes a cell-cycle arrest.

  10. Mitogen-activated protein kinase kinase 4 deficiency in cardiomyocytes causes connexin 43 (zeige GJA1 Antikörper) reduction and couples hypertrophic signals to ventricular arrhythmogenesis.

Arabidopsis thaliana Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) Interaktionspartner

  1. MKK4, MKK5 (zeige MAP2K5 Antikörper), MKK7 (zeige MAP2K7 Antikörper), and MKK9, are responsible for the activation of MPK3 (zeige MAPK3 Antikörper) and MPK6 (zeige MAPK6 Antikörper) by melatonin, indicating that melatonin-mediated innate immunity is triggered by MAPK (zeige MAPK1 Antikörper) signaling through MKK4/5/7/9-MPK3 (zeige MAPK3 Antikörper)/6 cascades.

  2. our data indicate that EDR1 (zeige PHC1 Antikörper) physically associates with MKK4/MKK5 (zeige MAP2K5 Antikörper) and negatively regulates the MAPK (zeige MAPK1 Antikörper) cascade to fine-tune plant innate immunity.

  3. Results suggest that the YDA-MKK4/MKK5 (zeige MAP2K5 Antikörper)-MPK3 (zeige MAPK3 Antikörper)/MPK6 (zeige MAPK6 Antikörper) cascade functions downstream of the ER receptor in regulating localized cell proliferation, which further shapes the morphology of plant organs.

  4. MKK4 is involved in the osmotic-stress response via its regulation of MPK3 (zeige MAPK3 Antikörper) activity.

  5. MKK4 is a key regulator of stomatal development and patterning.

MAP2K4 Antigen-Profil

Beschreibung des Gens

This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver.

Alternative names and synonyms associated with MAP2K4

  • mitogen-activated protein kinase kinase 4 (map2k4) Antikörper
  • MAP kinase kinase 4 (Mkk4) Antikörper
  • CG12798 (CG12798) Antikörper
  • mitogen activated protein kinase kinase 4 (Map2k4) Antikörper
  • mitogen activated protein kinase kinase 7 (Map2k7) Antikörper
  • mitogen-activated protein kinase kinase 4 (MAP2K4) Antikörper
  • mitogen-activated protein kinase kinase 4 (Map2k4) Antikörper
  • mitogen-activated protein kinase kinase 4 (MKK4) Antikörper
  • mitogen-activated protein kinase kinase 4a (map2k4a) Antikörper
  • 2 Antikörper
  • 142758_at Antikörper
  • ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 Antikörper
  • ATMEK4 Antikörper
  • ATMKK4 Antikörper
  • CG9738 Antikörper
  • CT27508 Antikörper
  • CT38386 Antikörper
  • D-MKK4 Antikörper
  • DmelCG12798 Antikörper
  • Dmel\\CG9738 Antikörper
  • dMkk4 Antikörper
  • F19C24.26 Antikörper
  • F19C24_26 Antikörper
  • hep Antikörper
  • JNKK Antikörper
  • JNKK1 Antikörper
  • Jnkk2 Antikörper
  • map2k4 Antikörper
  • MAP KINASE KINASE 4 Antikörper
  • MAPKK4 Antikörper
  • Mapkk7 Antikörper
  • MEK4 Antikörper
  • Mek7 Antikörper
  • mitogen-activated protein kinase kinase 4 Antikörper
  • MKK4 Antikörper
  • MKK4A-l Antikörper
  • Mkk7 Antikörper
  • Mpk4 Antikörper
  • PRKMK4 Antikörper
  • SAPKK-1 Antikörper
  • SAPKK1 Antikörper
  • SEK1 Antikörper
  • SEK1/MKK4 Antikörper
  • Serk1 Antikörper
  • SKK1 Antikörper
  • xmek2 Antikörper
  • zgc:136500 Antikörper

Bezeichner auf Proteinebene für MAP2K4

CG9738-PA , CG9738-PB , CG9738-PC , JNK kinase 2 , Map kinase kinase 4 , Mkk4-PA , Mkk4-PB , Mkk4-PC , drosophila MAP kinase kinase 4 , CG12798 , CG12798-PA , MAP2K4delta , SAPK/ERK kinase 1 , dual specificity mitogen-activated protein kinase kinase 4 , JNK-activating kinase 2 , JNKK 2 , MAP kinase kinase 7 , MAPK/ERK kinase 7 , MAPKK 7 , MEK 7 , c-Jun N-terminal kinase kinase 2 , dual specificity mitogen-activated protein kinase kinase 7 , JNK activating kinase 1 , JNK-activated kinase 1 , JNK-activating kinase 1 , MAP kinase kinase 4 , MAPK/ERK kinase 4 , MAPKK 4 , MEK 4 , c-Jun N-terminal kinase kinase 1 , stress-activated protein kinase kinase 1 , C-JUN N-terminal kinase kinase 1 , JNK kinase 1 , JNKK 1 , SAPK/Erk/kinase 1 , mitogen activated protein kinase kinase 4, variant 1 , mitogen-activated protein kinase kinase 4 , mkk4a

GENE ID SPEZIES
100135013 Xenopus (Silurana) tropicalis
41020 Drosophila melanogaster
3355004 Drosophila melanogaster
287398 Rattus norvegicus
363855 Rattus norvegicus
6416 Homo sapiens
26398 Mus musculus
489508 Canis lupus familiaris
841591 Arabidopsis thaliana
403052 Danio rerio
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