anti-MAP2K1 (MAP2K1) Antikörper

Bezeichnung:
anti-Mitogen-Activated Protein Kinase Kinase 1 Antikörper (MAP2K1)
Auf www.antikoerper-online.de finden Sie aktuell 628 Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) Antikörper von 32 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MAP2K1 Kits (31) und MAP2K1 Proteine (22) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 721 MAP2K1 Produkte verfügbar.
Synonyme:
ATMEK1, CFC3, F20B18.180, F20B18_180, MAP kinase/ ERK kinase 1, MAPKK1, MEK, mek-2, MEK1, MEKK1, MITOGEN ACTIVATED PROTEIN KINASE KINASE, MITOGEN ACTIVATED PROTEIN KINASE KINASE 1, MKK1, NMAPKK, Prkmk1, si:ch211-242m18.2, wu:fj56a12, wu:fj61b01, zgc:56557

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Am meisten referenzierte anti-MAP2K1 Antikörper

  1. Human Monoclonal MAP2K1 Primary Antibody für IP, WB - ABIN2853620 : Riesmeier, Willmitzer, Frommer: Evidence for an essential role of the sucrose transporter in phloem loading and assimilate partitioning. in The EMBO journal 1994 (PubMed)
    Zeige alle 6 Referenzen für 2853620

  2. Chicken Monoclonal MAP2K1 Primary Antibody für BI, IP - ABIN967762 : Aplin, Stewart, Assoian, Juliano: Integrin-mediated adhesion regulates ERK nuclear translocation and phosphorylation of Elk-1. in The Journal of cell biology 2001 (PubMed)
    Zeige alle 5 Referenzen für 967762

  3. Human Polyclonal MAP2K1 Primary Antibody für EIA, IHC (p) - ABIN358157 : Ohren, Chen, Pavlovsky, Whitehead, Zhang, Kuffa, Yan, McConnell, Spessard, Banotai, Mueller, Delaney, Omer, Sebolt-Leopold, Dudley, Leung, Flamme, Warmus, Kaufman, Barrett, Tecle, Hasemann: Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition. in Nature structural & molecular biology 2004 (PubMed)
    Zeige alle 5 Referenzen für 358157

  4. Human Polyclonal MAP2K1 Primary Antibody für IHC (p), WB - ABIN1881525 : Zheng, Fiumara, Li, Georgakis, Snell, Younes, Vauthey, Carbone, Younes: MEK/ERK pathway is aberrantly active in Hodgkin disease: a signaling pathway shared by CD30, CD40, and RANK that regulates cell proliferation and survival. in Blood 2003 (PubMed)
    Zeige alle 5 Referenzen für 1881525

  5. Human Polyclonal MAP2K1 Primary Antibody für EIA - ABIN358538 : Naegele, Morley: Molecular cross-talk between MEK1/2 and mTOR signaling during recovery of 293 cells from hypertonic stress. in The Journal of biological chemistry 2004 (PubMed)
    Zeige alle 4 Referenzen für 358538

  6. Human Monoclonal MAP2K1 Primary Antibody für WB - ABIN967599 : Eblen, Slack, Weber, Catling: Rac-PAK signaling stimulates extracellular signal-regulated kinase (ERK) activation by regulating formation of MEK1-ERK complexes. in Molecular and cellular biology 2002 (PubMed)
    Zeige alle 3 Referenzen für 967599

  7. Human Polyclonal MAP2K1 Primary Antibody für IHC (p), WB - ABIN197388 : Zebisch, Staber, Delavar, Bodner, Hiden, Fischereder, Janakiraman, Linkesch, Auner, Emberger, Windpassinger, Schimek, Hoefler, Troppmair, Sill: Two transforming C-RAF germ-line mutations identified in patients with therapy-related acute myeloid leukemia. in Cancer research 2006 (PubMed)
    Zeige alle 3 Referenzen für 197388

  8. Human Polyclonal MAP2K1 Primary Antibody für WB - ABIN197066 : Burroughs, Oh, Barrett, DiAugustine et al.: Phosphatidylinositol 3-kinase and mek1/2 are necessary for insulin-like growth factor-I-induced vascular endothelial growth factor synthesis in prostate epithelial cells: a role for hypoxia-inducible ... in Molecular cancer research : MCR 2003 (PubMed)
    Zeige alle 2 Referenzen für 197066

  9. Human Polyclonal MAP2K1 Primary Antibody für IHC (p), WB - ABIN196944 : Shen, Ouyang, Qu, Alonso, Sperzel, Mustelin, Kaplan, Feng: Grap negatively regulates T-cell receptor-elicited lymphocyte proliferation and interleukin-2 induction. in Molecular and cellular biology 2002 (PubMed)
    Zeige alle 2 Referenzen für 196944

Weitere Antikörper gegen MAP2K1 Interaktionspartner

Human Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) Interaktionspartner

  1. MEK1 is constitutively and mainly phosphorylated at the Thr (zeige TRH Antikörper)-292, Ser (zeige SIGLEC1 Antikörper)-298, Thr (zeige TRH Antikörper)-386, and Thr (zeige TRH Antikörper)-388 residues in vivo, and combinations of phosphorylations at these four residues produce at least six phosphorylated variants of MEK1. The phosphorylation statuses of Thr (zeige TRH Antikörper)-292, Ser (zeige SIGLEC1 Antikörper)-298, Thr (zeige TRH Antikörper)-386, and Thr (zeige TRH Antikörper)-388 residues vary widely during activation and deactivation of the MAPK (zeige MAPK1 Antikörper) pathway.

  2. TNFRSF14 (zeige TNFRSF14 Antikörper) and MAP2K1 mutations are the most frequent genetic alterations found in pediatric-type follicular lymphoma (PTFL) and occur independently in most cases, suggesting that both mutations might play an important role in PTFL lymphomagenesis.

  3. There was no statistically significant association between BRAF (zeige BRAF Antikörper) or MAP2K1 mutation and anatomic site, unifocal versus multifocal presentation, or clinical outcome in Langerhans cell histiocytosis.

  4. High MEK1 expression is associated with inflammation.

  5. Lgr4 (zeige LGR4 Antikörper) is a critical positive factor for skin tumorigenesis by mediating the activation of MEK1/ERK1/2 (zeige MAPK1/3 Antikörper) and Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) pathways.

  6. somatic mutations in MAP2K1 are a common cause of extracranial arteriovenous malformation

  7. MEK1 mutation is associated with central nervous system metastases of non-small cell lung cancer.

  8. The MAP2K1 mutation analysis of three hairy cell leukemia cases, one hairy cell leukemia-variant case, and three splenic marginal zone lymphoma cases revealed negative results.

  9. Data show that mitogen-activated protein kinase (zeige MAPK1 Antikörper) kinases MEK1/2 inhibitor pimasertib (MEKI) sensitized the cells to apoptosis through its ability to promote a G1 cell cycle arrest.

  10. the purpose of this paper was to investigate MAPK (zeige MAPK1 Antikörper) downstream signalling molecules in Natural killer cell phenotypes from Chronic Fatigue Syndrome/Myalgic Encephalomyelitis patients.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) Interaktionspartner

  1. Lgr4 (zeige LGR4 Antikörper) is a critical positive factor for skin tumorigenesis by mediating the activation of MEK1/ERK1/2 (zeige MAPK1/3 Antikörper) and Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) pathways.

  2. FGF2 (zeige FGF2 Antikörper) is an extracellular inducer of COUP-TFII (zeige NR2F2 Antikörper) expression and may suppress the osteogenic potential of mesenchymal cells by inducing COUP-TFII (zeige NR2F2 Antikörper) expression prior to the onset of osteogenic differentiation

  3. REDD1 (zeige DDIT4 Antikörper) is required for normal insulin (zeige INS Antikörper)-stimulated signaling, and a subtle balance exists between MEK1/2, REDD1 (zeige DDIT4 Antikörper), and mTOR (zeige FRAP1 Antikörper)

  4. blood glucose levels are reduced by suppression of MEK1 expression in the liver of db/db (zeige LEPR Antikörper) mice

  5. MEK1 and MEK2 (zeige MAP2K2 Antikörper) can substitute for each other but a minimum amount of MEK (zeige MDK Antikörper) is critical for placenta development and embryo survival

  6. Aberrant phosphorylation of AKT (zeige AKT1 Antikörper) and MEK (zeige MDK Antikörper) signalling pathways was identified in cells carrying mutant huntingtin (zeige HTT Antikörper).

  7. An essential function for MEK1 in macrophages in regulating the ERK1/2 (zeige MAPK1/3 Antikörper) and STAT4 (zeige STAT4 Antikörper) pathways in response to TLR4 (zeige TLR4 Antikörper) activation.

  8. Nuclear enrichment of MEK1 physically sequesters peroxisome proliferator-activated receptor gamma (PPARgamma (zeige PPARG Antikörper)), inhibiting adipogenesis and disrupting ERK (zeige EPHB2 Antikörper) signaling.

  9. MEK1 is inhibited by phosphorylation at Thr (zeige TRH Antikörper)-292/286 by Cdk5 (zeige CDK5 Antikörper), ERK (zeige EPHB2 Antikörper), and Cdk1 (zeige CDK1 Antikörper).

  10. The effect of Akt1 (zeige AKT1 Antikörper) and Mek1 on extracellular matrix synthesis was reconciled through the activation of p70 S6-kinase (zeige PRKACB Antikörper).

Xenopus laevis Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) Interaktionspartner

  1. in FGFR1 (zeige FGFR1 Antikörper) signalling JNK1 (zeige MAPK8 Antikörper) phosphorylation depends on ERK2 (zeige MAPK1 Antikörper)

  2. The data demonstrate that ERK (zeige MAPK1 Antikörper) phosphorylation of UBF prevents DNA bending by its first two HMG (zeige SSRP1 Antikörper) boxes, leading to a cooperative unfolding of the enhancesome

  3. We propose that Erk2 MAP kinase (zeige MAPK1 Antikörper) phosphorylation of Vg1RBP (zeige IGF2BP3 Antikörper) regulates the protein:protein-mediated association of Vg1 mRNP with the cytoskeleton and/or ER.

Rabbit Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) Interaktionspartner

  1. Extracellular signal-regulated kinase (ERK (zeige MAPK1 Antikörper)) pathway plays a role in dedifferentiation of rabbit articular chondrocytes.

  2. KSR (zeige KSR1 Antikörper) interacts with a regulatory Raf (zeige RAF1 Antikörper) molecule in cis (zeige CISH Antikörper) to induce a conformational switch of MEK, facilitating MEK's phosphorylation by a separate catalytic Raf (zeige RAF1 Antikörper) molecule in trans

Pig (Porcine) Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) Interaktionspartner

  1. 20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism.

Arabidopsis thaliana Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) Interaktionspartner

  1. Data indicate that MEKK2 (zeige MAP3K2 Antikörper) is required for the mekk1 (zeige MAP3K1 Antikörper), mkk1 mkk2 (zeige MAP2K2 Antikörper), and mpk4 (zeige MAPK4 Antikörper) autoimmune phenotypes.

  2. Data suggest that the MEKK1 (zeige MAP3K1 Antikörper)-MKK1/MKK2 (zeige MAP2K2 Antikörper)-MPK4 (zeige MAPK4 Antikörper) kinase cascade negatively regulates MEKK2 (zeige MAP3K2 Antikörper) and activation of MEKK2 (zeige MAP3K2 Antikörper) triggers SUMM2-mediated immune responses.

  3. miR (zeige MYLIP Antikörper)-1826 plays an important role as tumor suppressor via CTNNB1 (zeige CTNNB1 Antikörper)/MEK1/VEGFC (zeige VEGFC Antikörper) downregulation in bladder cancer.

  4. ETS1 (zeige ETS1 Antikörper) is probably mediating high CIP2A (zeige KIAA1524 Antikörper) expression in human cancers with increased EGFR (zeige EGFR Antikörper)-MEK1/2-ERK (zeige MAPK1 Antikörper) pathway activity

  5. An analysis of the interation of MEKK1 (zeige MAP3K1 Antikörper) and MEK1 in response to wounding stress in A. thaliana seedlings is presented.

  6. This study demonstrated that the MKK1 signalling pathway modulates the expression of genes responding to elicitors and plays an important role in pathogen defence.

  7. These results suggest that the formation of SUMO-1 (zeige SUMO1 Antikörper) foci is regulated by the MEK-ERK (zeige MAPK1 Antikörper) pathway and may induce apoptosis.

  8. AtMEK1 is a crucial mediator in plant stress signal transduction.

  9. double loss-of-function mutant (mkk1/2) of MKK1 and MKK2 (zeige MAP2K2 Antikörper) is shown to have marked phenotypes in development and disease resistance similar to those of the single mekk1 (zeige MAP3K1 Antikörper) and mpk4 (zeige MAPK4 Antikörper) mutants

  10. Activation of MPK4 (zeige MAPK4 Antikörper) by flg22 is impaired in the mkk1 mkk2 (zeige MAP2K2 Antikörper) double mutants, suggesting that MKK1 and MKK2 (zeige MAP2K2 Antikörper) function together with MPK4 (zeige MAPK4 Antikörper) and MEKK1 (zeige MAP3K1 Antikörper) in a MAP kinase (zeige MAPK1 Antikörper) cascade to negatively regulate innate immune responses in plants.

MAP2K1 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.

Alternative names and synonyms associated with MAP2K1

  • mitogen activated protein kinase kinase 1 (Map2k1) Antikörper
  • mitogen-activated protein kinase kinase 1 (MAP2K1) Antikörper
  • mitogen-activated protein kinase kinase 1 (Map2k1) Antikörper
  • mitogen-activated protein kinase kinase 1 (map2k1) Antikörper
  • mitogen-activated protein kinase kinase 1 (MEK1) Antikörper
  • ATMEK1 Antikörper
  • CFC3 Antikörper
  • F20B18.180 Antikörper
  • F20B18_180 Antikörper
  • MAP kinase/ ERK kinase 1 Antikörper
  • MAPKK1 Antikörper
  • MEK Antikörper
  • mek-2 Antikörper
  • MEK1 Antikörper
  • MEKK1 Antikörper
  • MITOGEN ACTIVATED PROTEIN KINASE KINASE Antikörper
  • MITOGEN ACTIVATED PROTEIN KINASE KINASE 1 Antikörper
  • MKK1 Antikörper
  • NMAPKK Antikörper
  • Prkmk1 Antikörper
  • si:ch211-242m18.2 Antikörper
  • wu:fj56a12 Antikörper
  • wu:fj61b01 Antikörper
  • zgc:56557 Antikörper

Bezeichner auf Proteinebene für MAP2K1

ERK activator kinase 1 , MAP kinase kinase 1 , MAP kinase/Erk kinase 1 , MAPK/ERK kinase 1 , MAPKK 1 , dual specificity mitogen-activated protein kinase kinase 1 , mitogen-activated protein kinase kinase 1 , MEK 1 , protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1) , dual specificity mitogen activated protein kinase kinase 1 , mitogen activated protein kinase kinase 1 , protein kinase, mitogen activated, kinase 1, p45 , MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2) , MEK1

GENE ID SPEZIES
170851 Rattus norvegicus
5604 Homo sapiens
478347 Canis lupus familiaris
26395 Mus musculus
379991 Xenopus laevis
415549 Gallus gallus
533199 Bos taurus
406728 Danio rerio
100009316 Oryctolagus cuniculus
100233191 Sus scrofa
828713 Arabidopsis thaliana
450188 Pan troglodytes
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