anti-SYNE2 (SYNE2) Antikörper

Bezeichnung:
anti-Spectrin Repeat Containing, Nuclear Envelope 2 Antikörper (SYNE2)
Auf www.antikoerper-online.de finden Sie aktuell 15 Spectrin Repeat Containing, Nuclear Envelope 2 (SYNE2) Antikörper von 6 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SYNE2 Kits (5) und SYNE2 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 23 SYNE2 Produkte verfügbar.
Synonyme:
6820443O06Rik, AW546258, D12Ertd777e, EDMD5, mKIAA1011, Nesp2, Nesp2g, Nesprin-2, NUA, NUANCE, RGD1305248, SYNE-2, SYNE2, TROPH
Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Ratte SYNE2 SYNE2 299151  
SYNE2 319565 Q6ZWQ0
SYNE2 23224 Q8WXH0

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Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-SYNE2 (SYNE2) Antikörper

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anti-Mouse (Murine) SYNE2 Antikörper:

anti-Human SYNE2 Antikörper:

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Am meisten referenzierte anti-SYNE2 Antikörper

  1. Human Monoclonal SYNE2 Primary Antibody für EM, ICC - ABIN1042628 : Zhen, Libotte, Munck, Noegel, Korenbaum: NUANCE, a giant protein connecting the nucleus and actin cytoskeleton. in Journal of cell science 2002 (PubMed)
    Zeige alle 3 Referenzen für 1042628

  2. Human Polyclonal SYNE2 Primary Antibody für ELISA, WB - ABIN565027 : Maddox, Collin, Ikeda, Pratt, Ikeda, Johnson, Hurd, Shopland, Naggert, Chang, Krebs, Nishina: A Mutation in Syne2 Causes Early Retinal Defects in Photoreceptors, Secondary Neurons, and Müller Glia. in Investigative ophthalmology & visual science 2015 (PubMed)

  3. Human Polyclonal SYNE2 Primary Antibody für ICC, IF - ABIN4338643 : Versaevel, Braquenier, Riaz, Grevesse, Lantoine, Gabriele: Super-resolution microscopy reveals LINC complex recruitment at nuclear indentation sites. in Scientific reports 2014 (PubMed)

Weitere Antikörper gegen SYNE2 Interaktionspartner

Mouse (Murine) Spectrin Repeat Containing, Nuclear Envelope 2 (SYNE2) Interaktionspartner

  1. SYNE2 is important for normal retinal development. We have determined that not only is photoreceptor nuclear migration affected, but also the positions of Muller glia and secondary neurons are disturbed early in retinal development

  2. nesprin-dependent recruitment of kinesin-1 to the nuclear envelope through the interaction of a conserved LEWD motif with kinesin light chain might be a general mechanism for cell-type-specific nuclear positioning during development.

  3. Loss of Nesprin 1 (zeige SYNE1 Antikörper) or 2, or both, led to impairment of gene expression changes in response to biomechanical stimuli. These data suggest a model whereby biomechanical signals are communicated from proteins of the outer nuclear membrane

  4. ectopic expression of BRAP2 (zeige BRAP Antikörper) inhibits nuclear localization of HMG20A (zeige HMG20A Antikörper) and NuMA1 (zeige NUMA1 Antikörper), and prevents nuclear envelope accumulation of SYNE2

  5. Data indicate roles for linkers of nucleus to cytoskeleton (LINC) molecules nesprin2giant and nesprin3, which anchor actin cap fibers to the nucleus.

  6. functions for Nesprin-2 at the nuclear envelope (NE) in gene regulation and in regulation of the actin cytoskeleton which impact on wound healing

  7. Syne-2, SUN1 (zeige SUN1 Antikörper) and SUN2 (zeige SUN2 Antikörper) play critical roles during interkinetic nuclear migration and photoreceptor cell migration in the mouse retina development.

  8. The p104 (zeige RB1 Antikörper) protein interacts with p85alpha and is involved in the regulation of p27(Kip1 (zeige CDKN1B Antikörper)) expression for the reduction of cellular proliferation.

  9. The Nesprin-2 the conserved C-terminal amino acids PPPX is essential for the interaction with a C-terminal region in Sun1 (zeige SUN1 Antikörper).

  10. SUN1 (zeige SUN1 Antikörper) interacts with nuclear lamin A (zeige LMNA Antikörper) and cytoplasmic nesprins (nesprin-1 (zeige SYNE1 Antikörper) and nesprin-2)to provide a physical connection between the nuclear lamina and the cytoskeleton.

Human Spectrin Repeat Containing, Nuclear Envelope 2 (SYNE2) Interaktionspartner

  1. The authors identified the nuclear envelope protein (zeige SUN2 Antikörper) nesprin-2 as a binding partner for fascin (zeige FSCN1 Antikörper) in a range of cell types in vitro and in vivo. Nesprin-2 interacts with fascin (zeige FSCN1 Antikörper) through a direct, F-actin-independent interaction, and this binding is distinct and separable from a role for fascin (zeige FSCN1 Antikörper) within filopodia at the cell periphery.

  2. these data identify N-terminal nesprin-2 variants as novel regulators of beta-catenin (zeige CTNNB1 Antikörper) signaling.

  3. We show that AMPH-1 (zeige AMPH Antikörper)/BIN1 (zeige BIN1 Antikörper) binds to nesprin and actin, as well as to the microtubule-binding protein CLIP170 (zeige CLIP1 Antikörper) in both species. We propose that BIN1 (zeige BIN1 Antikörper) has a direct and evolutionarily conserved role in nuclear positioning, altered in myopathies.

  4. nesprin-1 (zeige SYNE1 Antikörper) and nesprin-2 both regulate nuclear and cytoplasmic architecture.

  5. nesprin-dependent recruitment of kinesin-1 to the nuclear envelope through the interaction of a conserved LEWD motif with kinesin light chain might be a general mechanism for cell-type-specific nuclear positioning during development.

  6. Each mutation in LMNA (zeige LMNA Antikörper) has a distinct impact on the Nersprin-2 interaction that substantially explains how distinct mutations in widely expressed genes lead to the formation of phenotypically different diseases.

  7. High Nesprin-2 expression is associated with colorectal cancer.

  8. ectopic expression of BRAP2 (zeige BRAP Antikörper) inhibits nuclear localization of HMG20A (zeige HMG20A Antikörper) and NuMA1 (zeige NUMA1 Antikörper), and prevents nuclear envelope accumulation of SYNE2.

  9. Multiple novel nesprin-1 (zeige SYNE1 Antikörper) and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.

  10. Study presents crystal structures of the human SUN2 (zeige SUN2 Antikörper)-KASH1/2 complex, i.e. SUN2 (zeige SUN2 Antikörper) complexed with the C-terminal 29 residues of human Nesprin-1 (zeige SYNE1 Antikörper) or -2 (the core of the LINC complex).

SYNE2 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with SYNE2

  • spectrin repeat containing, nuclear envelope 2 (Syne2) Antikörper
  • spectrin repeat containing, nuclear envelope 2 (SYNE2) Antikörper
  • spectrin repeat containing, nuclear envelope 2 (syne2) Antikörper
  • spectrin repeat containing, nuclear envelope 2 (LOC100227700) Antikörper
  • spectrin repeat containing, nuclear envelope 2 (LOC100346489) Antikörper
  • 6820443O06Rik Antikörper
  • AW546258 Antikörper
  • D12Ertd777e Antikörper
  • EDMD5 Antikörper
  • mKIAA1011 Antikörper
  • Nesp2 Antikörper
  • Nesp2g Antikörper
  • Nesprin-2 Antikörper
  • NUA Antikörper
  • NUANCE Antikörper
  • RGD1305248 Antikörper
  • SYNE-2 Antikörper
  • SYNE2 Antikörper
  • TROPH Antikörper

Bezeichner auf Proteinebene für SYNE2

spectrin repeat containing, nuclear envelope 2 , synaptic nuclear envelope 2 , nesprin-2-like , nesprin 2 , nesprin-2 , nuance , nuclear envelope spectrin repeat protein 2 , nucleus and actin connecting element protein , synaptic nuclear envelope protein 2 , nuclear envelope spectrin repeat-2 , polytrophin , synaptic nuclei expressed gene 2

GENE ID SPEZIES
299151 Rattus norvegicus
423509 Gallus gallus
490729 Canis lupus familiaris
540504 Bos taurus
746581 Pan troglodytes
100061983 Equus caballus
100216251 Xenopus (Silurana) tropicalis
100227700 Taeniopygia guttata
100346489 Oryctolagus cuniculus
100391491 Callithrix jacchus
100554331 Anolis carolinensis
319565 Mus musculus
23224 Homo sapiens
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