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anti-RAB8A (RAB8A) Antikörper

Bezeichnung:
anti-RAB8A, Member RAS Oncogene Family Antikörper (RAB8A)
Auf www.antikoerper-online.de finden Sie aktuell 84 RAB8A, Member RAS Oncogene Family (RAB8A) Antikörper von 18 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen RAB8A Proteine (16) und RAB8A Kits (9) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 113 RAB8A Produkte verfügbar.
Synonyme:
AA409338, c-mel, DDBDRAFT_0206521, DDBDRAFT_0214885, DDB_0206521, DDB_0214885, HSH2D, Mel, Rab8, rab8A, zgc:162699

Meistgesuchte Reaktivitäten zu anti-RAB8A (RAB8A) Antikörper

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anti-Human RAB8A Antikörper:

anti-Mouse (Murine) RAB8A Antikörper:

anti-Rat (Rattus) RAB8A Antikörper:

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Am meisten referenzierte anti-RAB8A Antikörper

  1. Dog (Canine) Monoclonal RAB8A Primary Antibody für IF, IP - ABIN968210 : Bahadoran, Aberdam, Mantoux, Buscà, Bille, Yalman, de Saint-Basile, Casaroli-Marano, Ortonne, Ballotti: Rab27a: A key to melanosome transport in human melanocytes. in The Journal of cell biology 2001 (PubMed)
    Zeige alle 5 Referenzen für ABIN968210

  2. Human Polyclonal RAB8A Primary Antibody für FACS, IHC (p) - ABIN1881723 : Kato, Sekine, Oh, Kim, Umezawa, Abe, Yokoyama-Kobayashi, Aoki: Construction of a human full-length cDNA bank. in Gene 1995 (PubMed)
    Zeige alle 2 Referenzen für ABIN1881723

  3. Cow (Bovine) Polyclonal RAB8A Primary Antibody für WB - ABIN2792290 : Roland, Kenworthy, Peranen, Caplan, Goldenring: Myosin Vb interacts with Rab8a on a tubular network containing EHD1 and EHD3. in Molecular biology of the cell 2007 (PubMed)

  4. Human Polyclonal RAB8A Primary Antibody für ELISA, WB - ABIN238664 : Yoshimura, Egerer, Fuchs, Haas, Barr: Functional dissection of Rab GTPases involved in primary cilium formation. in The Journal of cell biology 2007 (PubMed)

Weitere Antikörper gegen RAB8A Interaktionspartner

Human RAB8A, Member RAS Oncogene Family (RAB8A) Interaktionspartner

  1. report the design of a bioavailable StRIP3 analogue that harbors two hydrophobic cross-links and exhibits increased binding affinity, combined with robust cellular uptake and extremely high proteolytic stability. Localization experiments reveal that this double-stapled peptide and its target protein Rab8a accumulate in the same cellular compartments

  2. knockdown of another Parkinson's disease (PD) gene, LRRK2 (zeige LRRK2 Antikörper), which phosphorylates Rab8a, similarly impairs retromer trafficking, secretory autophagy and Golgi-derived vesicle secretion, thus demonstrating converging roles of two PD genes TMEM230 and LRRK2 (zeige LRRK2 Antikörper) on Rab8a function, and suggesting that retromer and secretory dysfunction play an important role in PD pathogenesis.

  3. Rab8 can induce Rac1- and Tiam1 (zeige TIAM1 Antikörper)-dependent cortical actin polymerization and focal adhesion disassembly through the proteases MT1-MMP (zeige MMP14 Antikörper) and calpain, and Rho-GTPase (zeige RACGAP1 Antikörper)-dependent mechanisms

  4. Data demonstrate that EHBP1L1 links Rab8 and the Bin1 (zeige BIN1 Antikörper)-dynamin (zeige DNM1 Antikörper) complex, which generates membrane curvature and excises the vesicle at the endocytic recycling compartment for apical transport.

  5. Further exploration of the NINL (zeige NINL Antikörper)-associated interactome identifies MICAL3 (zeige MICAL3 Antikörper), a protein known to interact with Rab8 and to play an important role in vesicle docking and fusion.

  6. The small GTPase (zeige RACGAP1 Antikörper) Rab8 interacts with VAMP-3 (zeige VAMP3 Antikörper) to regulate the delivery of recycling T-cell receptors to the immune synapse.

  7. the role of Rabin8 (zeige RAB3IP Antikörper) (a mammalian ortholog of Sec2p) with Rab8-nucleotide-exchange factor activity in autophagy in mammalian cells, was examined.

  8. DLC3 (zeige STARD8 Antikörper) is recruited to Rab8-positive membrane tubules and is required for the integrity of the Rab8 and Golgi compartments.

  9. Rab8A GTPase (zeige RACGAP1 Antikörper) Ser (zeige SIGLEC1 Antikörper)(111) phosphorylation is not directly regulated by PINK1 (zeige PINK1 Antikörper) in vitro and demonstrate in cells the time course of Ser (zeige SIGLEC1 Antikörper)(111) phosphorylation of Rab8A, 8B and 13 is markedly delayed compared to phosphorylation of Parkin (zeige PARK2 Antikörper) at Ser (zeige SIGLEC1 Antikörper)(65).

  10. Intercellular transfer of transferrin receptor by a contact-, Rab8-dependent mechanism involving tunneling nanotubes.

Zebrafish RAB8A, Member RAS Oncogene Family (RAB8A) Interaktionspartner

  1. Cc2d2a (zeige CC2D2A Antikörper), localized at the photoreceptor connecting cilium/transition zone, facilitates protein transport through a role in Rab8-dependent vesicle trafficking and fusion.

  2. Data show that elipsa (zeige TRAF3IP1 Antikörper) encodes a coiled-coil polypeptide that localizes to cilia, and that it interacts genetically with Rabaptin5, a well-studied regulator of endocytosis, which in turn interacts with Rab8, a small GTPase (zeige RACGAP1 Antikörper), known to localize to cilia.

Mouse (Murine) RAB8A, Member RAS Oncogene Family (RAB8A) Interaktionspartner

  1. With CRISPR/Cas9-mediated gene editing to stably knock out and recover Rab8a in macrophage cell lines, this study matches Akt (zeige AKT1 Antikörper) signaling profiles with cytokine outputs, confirming that Rab8a is a novel regulator of the Akt (zeige AKT1 Antikörper)/mammalian target of rapamycin (mTOR (zeige FRAP1 Antikörper)) pathway downstream of multiple Toll (zeige TLR4 Antikörper)-like Receptors.

  2. these results indicate an indispensable role for Rab8A in insulin (zeige INS Antikörper)-regulated GLUT4 (zeige SLC2A4 Antikörper) trafficking in C2C12 cells.

  3. Results highlight a novel role of Rab8, downstream of IFT20, in the pathway that regulates T cell receptor (TCR) recycling, through recruiting VAMP-3 and promoting the fusion with the synaptic membrane of endosomes carrying TCR cargoes.

  4. Data demonstrate that EHBP1L1 links Rab8 and the Bin1 (zeige BIN1 Antikörper)-dynamin (zeige DNM1 Antikörper) complex, which generates membrane curvature and excises the vesicle at the endocytic recycling compartment for apical transport.

  5. The small GTPase (zeige RACGAP1 Antikörper) Rab8 interacts with VAMP-3 (zeige VAMP3 Antikörper) to regulate the delivery of recycling T-cell receptors to the immune synapse.

  6. Rab8a thus controls Wnt (zeige WNT2 Antikörper) delivery in producing cells and is crucial for Paneth cell maturation.

  7. Rab8a acts as an activator of Fsp27 (zeige CIDEC Antikörper)-mediated LD fusion and growth.

  8. Simultaneous loss of Rab8a and Rab8b (zeige RAB8B Antikörper) has little effect on ciliogenesis, whereas additional loss of Rab10 (zeige RAB10 Antikörper) greatly affects ciliogenesis.

  9. acidosis-induced NBCe1 (zeige SLC4A4 Antikörper)-A, but not NBCe1 (zeige SLC4A4 Antikörper)-B/C, trafficking is mediated by Rab8a.

  10. AS160 (zeige TBC1D4 Antikörper) and Rab8a regulate membrane recruitment of CD36 (zeige CD36 Antikörper).

RAB8A Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.

Alternative names and synonyms associated with RAB8A

  • rab8A protein (rab8A) Antikörper
  • Rab GTPase (rab8A) Antikörper
  • RAB8A, member RAS oncogene family (RAB8A) Antikörper
  • RAB8A, member RAS oncogene family (rab8a) Antikörper
  • RAB8A, member RAS oncogene family (Rab8a) Antikörper
  • AA409338 Antikörper
  • c-mel Antikörper
  • DDBDRAFT_0206521 Antikörper
  • DDBDRAFT_0214885 Antikörper
  • DDB_0206521 Antikörper
  • DDB_0214885 Antikörper
  • HSH2D Antikörper
  • Mel Antikörper
  • Rab8 Antikörper
  • rab8A Antikörper
  • zgc:162699 Antikörper

Bezeichner auf Proteinebene für RAB8A

rab8A protein , hematopoietic SH2 domain containing , ras-related protein Rab-8A , RAB8A, member RAS oncogene family , member RAS oncogene family , Ras-related protein Rab-8A , mel transforming oncogene (RAB8 homolog) , mel transforming oncogene (derived from cell line NK14) , mel transforming oncogene (derived from cell line NK14)- RAB8 homolog , oncogene c-mel , ras-associated protein RAB8 , RAB8, member RAS oncogene family , cell line NK14 derived transforming oncogene

GENE ID SPEZIES
553899 Lotus japonicus
8622514 Dictyostelium discoideum AX4
468760 Pan troglodytes
100125217 Xenopus (Silurana) tropicalis
100380328 Salmo salar
4218 Homo sapiens
403773 Canis lupus familiaris
100125881 Bos taurus
571897 Danio rerio
100037230 Xenopus laevis
428352 Gallus gallus
17274 Mus musculus
117103 Rattus norvegicus
100174026 Pongo abelii
101092668 Felis catus
100511006 Sus scrofa
100302063 Ovis aries
100734132 Cavia porcellus
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