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anti-Mouse (Murine) MAD1L1 Antikörper:
anti-Human MAD1L1 Antikörper:
anti-Rat (Rattus) MAD1L1 Antikörper:
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Human Polyclonal MAD1L1 Primary Antibody für ChIP, ICC - ABIN442732
Chen, Yeh, Huang, Yeh, Juang: The spindle checkpoint protein MAD1 regulates the expression of E-cadherin and prevents cell migration. in Oncology reports 2011
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Human Polyclonal MAD1L1 Primary Antibody für ICC, IF - ABIN152001
Sze, Ching, Jin, Ng: Role of a novel splice variant of mitotic arrest deficient 1 (MAD1), MAD1beta, in mitotic checkpoint control in liver cancer. in Cancer research 2008
Human Polyclonal MAD1L1 Primary Antibody für IP, WB - ABIN152962
Jones: Transcriptional regulation by dimerization: two sides to an incestuous relationship. in Cell 1990
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MAD1 (zeige MXD1 Antikörper) and Proto-Oncogene (zeige RAB1A Antikörper) Proteins c-myc (zeige MYC Antikörper) reciprocally regulate ribosomal DNA transcription, providing a mechanism for coordination of ribosome biogenesis and cell growth
MAD1 (zeige MXD1 Antikörper) is present in mouse oocytes at all stages during the first meiosis and that it participates in spindle checkpoint during meiosis
Data show that the loss of Trrap (zeige TRRAP Antikörper) leads to chromosome missegregation, mitotic exit failure and compromised mitotic checkpoints, which are caused by defective Trrap (zeige TRRAP Antikörper)-mediated transcription of the mitotic checkpoint (zeige BUB3 Antikörper) proteins Mad1 (zeige MXD1 Antikörper) and Mad2 (zeige MXI1 Antikörper).
identified mouse Telomeric Repeat Binding Factor 1 (Trf1 (zeige TERF1 Antikörper)) as a protein that interacts directly with the spindle checkpoint protein Mad1 (zeige MXD1 Antikörper) and the mitotic kinase Nek2 (zeige NEK2 Antikörper)
Together these data demonstrate that the MYC (zeige MYC Antikörper)-antagonist MAD1 (zeige MXD1 Antikörper) and cyclin-dependent kinase inhibitor p27(Kip1 (zeige CDKN1B Antikörper)) cooperate to regulate the self-renewal and differentiation of HSCs in a context-dependent manner.
the simultaneous knockdown of p18 (zeige CDKN2C Antikörper), p27 (zeige CDKN1B Antikörper) and MAD1 (zeige MXD1 Antikörper) with a medium of only stem cell factor (zeige KITLG Antikörper) can induce long-term culture-initiating cell expansion despite the loss of engraftment ability
This study showed that MAD1L1 as a susceptibility gene for both of these genetically overlapping disorders is associated with a decreased bottom-up responsiveness of the mesolimbic reward system and related cortical regions involved in the salience network as well as with reduced top-down control processes.
Results show that low DNA methylation (zeige HELLS Antikörper) levels of LINC00682, MAD1L1, and LINE-2 was strongly correlated with hepatocellular carcinomas recurrence, patient disease-free survival, and/or overall survival.
MAD1L1 positive expression may be associated with tumour progression and metastasis in small-cell lung cancer (SCLC) and may thus serve as a new biomarker for prognosis in these patients.
In this review, we highlight a novel Mad1 role in chromosome alignment, which is the first conserved mechanism that links the spindle assembly checkpoint and kinesin-mediated chromosome gliding.
MAD1L1 Arg558His and MAD2L1 (zeige MAD2L1 Antikörper) Leu84Met interaction with smoking increase the risk of colorectal cancer
MAD1L1 rs12666575 polymorphism may play a protective role against schizophrenia (SCZ) in the Chinese population. rs12666575 may be associated with general psychopathology and thought disturbance in SCZ patients.
We also show that replication perturbations result in relocalization of MAD1 (zeige MXD1 Antikörper)/MAD2 (zeige MAD2L1 Antikörper) in human cells, suggesting that the role of SAC (zeige ADCY10 Antikörper) in DNA repair is conserved.
Mad1 (zeige MXD1 Antikörper) has a role in secretion and cell migration.
MAD1 (zeige MXD1 Antikörper) kinetochore localization dictates the spindle assembly checkpoint in metaphase.
This article reviews Mad1 (zeige MXD1 Antikörper) and Mad2 (zeige MAD2L1 Antikörper) - structural and functional relationship with implication in genetic diseases, specifically in cancer. [review]
MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene.
MAD1-like protein 1
, mitotic arrest deficient 1-like 1
, mitotic arrest deficient 1-like protein 1
, mitotic spindle assembly checkpoint protein MAD1
, mitotic checkpoint MAD1 protein homolog
, mitotic-arrest deficient 1, yeast, homolog-like 1
, tax-binding protein 181
, tumor protein p53 inducible protein 9