anti-Human Coagulation Factor XII (Hageman Factor) Antikörper für Functional Studies

Recommended Coagulation Factor XII (Hageman Factor) Antibody (geliefert von: Anmelden zum Anzeigen )

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Coagulation Factor XII (Hageman Factor) (F12) Antikörper
  • HAE3
  • HAEX
  • HAF
  • FXII
  • coagulation factor XII (Hageman factor)
  • F12
Epitop
Light Chain
22
16
15
6
6
5
4
3
3
3
3
2
1
1
1
1
1
1
1
1
1
Reaktivität
Human
153
34
29
2
1
Wirt
Maus
90
29
24
18
1
Klonalität
Monoklonal
Konjugat
Unkonjugiert
12
9
8
4
4
4
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Functional Studies (Func)
107
88
21
21
11
9
8
5
5
4
4
2
2
2
2
1
1
1
1
Hersteller
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Produktnummer ABIN111207
891,00 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN212811 Func ELISA Mouse IgG1 Anmelden zum Anzeigen

Ähnliche anti-Coagulation Factor XII (Hageman Factor) Antikörper

Applikation / Reaktivität Human
ELISA 81 Antikörper
ELISA (Capture) 1 Antikörper
ELISA (Detection) 5 Antikörper
Enzyme Immunoassay (EIA) 9 Antikörper
Functional Studies (Func) 2 Antikörper
Immunochromatography (IC) 1 Antikörper
Immunocytochemistry (ICC) 3 Antikörper
Immunodiffusion (ID) 5 Antikörper
Immunoelectrophoresis (IEP) 4 Antikörper
Immunofluorescence (IF) 2 Antikörper
Immunofluorescence (fixed cells) (IF/ICC) 1 Antikörper
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antikörper
Immunohistochemistry (IHC) 19 Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 21 Antikörper
Immunoprecipitation (IP) 8 Antikörper
Neutralization (Neut) 1 Antikörper
Proximity Ligation Assay (PLA) 2 Antikörper

General

Antigen Coagulation Factor XII (Hageman Factor) (F12) Antikörper
Epitop Light Chain
(22), (16), (15), (6), (6), (5), (4), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(153), (34), (29), (2), (1)
Wirt Maus
(90), (29), (24), (18), (1)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Unkonjugiert
(12), (9), (8), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Functional Studies (Func)
(107), (88), (21), (21), (11), (9), (8), (5), (5), (4), (4), (2), (2), (2), (2), (1), (1), (1), (1)
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Produktdetails

Antigendetails Anwendungsinformationen Handhabung Bilder
Spezifität Reacts with the light chain of human Factor XII and at 100nM inhibits 50 % of Factor XII activity.
Reinigung Protein G affinity chromatography
Immunogen Purified human Factor XII
Klon 802
Isotyp IgG1

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Coagulation Factor XII (F12) (F12 Antibody Abstract)
Hintergrund Coagulation factor XII circulates in blood as a zymogen. This single chain zymogen is converted to a two chain serine protease with an heavy chain (alpha factor XIIa) and a light chain. The heavy chain contains two fibronectin type domains, two epidermal growth factor (EGF) like domains, a kringle domain and a proline rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta factor XIIa light chain and the alpha factor XIIa light chain becomes beta factor XIIa heavy chain. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha factor XIIa and then to beta factor XIIa. The active factor XIIa participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. It activates coagulation factors VII and XI. Defects in Factor XII gene do not cause any clinical symptoms and the sole effect is that whole blood clotting time is prolonged.Synonyms: HAF, Hageman factor
Gen-ID 2161
NCBI Accession NP_000496
UniProt P00748
Pathways Komplementsystem

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Bilder zurück nach oben
Applikationshinweise ELISA, to detect/quantitate Factor XII and in coagulation assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Bilder zurück nach oben
Konzentration 0.95 mg/mL
Buffer PBS, pH 7.4, without preservative
Konservierungsmittel Without preservative
Handhabung Aliquot to Avoid multiple freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung Upon receipt, store at -20 °C to -70 °C.