anti-Human Coagulation Factor XII (Hageman Factor) Antikörper für ELISA

Recommended Coagulation Factor XII (Hageman Factor) Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Coagulation Factor XII (Hageman Factor) (F12) Antikörper
  • HAE3
  • HAEX
  • HAF
  • FXII
  • coagulation factor XII (Hageman factor)
  • F12
Epitop
AA 191-301
22
16
15
7
6
5
4
3
3
3
3
2
1
1
1
1
1
1
1
1
1
Reaktivität
Human
154
34
29
2
1
Wirt
Maus
91
29
24
18
1
Klonalität
Monoklonal
Konjugat
Unkonjugiert
12
9
8
4
4
4
1
1
1
1
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
107
87
21
21
11
9
9
5
5
4
4
2
2
2
2
2
1
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN395773
$ 450.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
10.534906 ABIN560829 PLA ELISA WB Mouse IgG2a kappa AA 191-300, partial Anmelden zum Anzeigen 3A3
1 ABIN2891184 ELISA WB Rabbit IgG AA 323-372, Cleaved-Arg372 Anmelden zum Anzeigen Polyclonal
1 ABIN364435 IEP IHC (p) IP ELISA Goat IgG Anmelden zum Anzeigen Polyclonal
1 ABIN4271079 ELISA IHC (p) WB Sheep IgG Anmelden zum Anzeigen Polyclonal
1 ABIN574164 IHC (p) ELISA WB Sheep IgG Anmelden zum Anzeigen Polyclonal
1 ABIN2471332 IHC ELISA WB Sheep IgG full length Anmelden zum Anzeigen Polyclonal
1 ABIN2600936 ELISA WB Rabbit IgG AA 9-38 Anmelden zum Anzeigen Polyclonal
1 ABIN2600937 ELISA WB Rabbit IgG AA 13-43 Anmelden zum Anzeigen Polyclonal
1 ABIN1894442 ELISA WB HRP Rabbit IgG AA 9-38 Anmelden zum Anzeigen Polyclonal
1 ABIN1894440 ELISA WB FITC Rabbit IgG AA 9-38 Anmelden zum Anzeigen Polyclonal
1 ABIN1894435 ELISA WB PE Rabbit IgG AA 13-43 Anmelden zum Anzeigen Polyclonal
1 ABIN1894437 ELISA WB APC Rabbit IgG AA 9-38 Anmelden zum Anzeigen Polyclonal
1 ABIN1894431 ELISA WB Alkaline Phosphatase (AP) Rabbit IgG AA 13-43 Anmelden zum Anzeigen Polyclonal
1 ABIN1894432 ELISA WB APC Rabbit IgG AA 13-43 Anmelden zum Anzeigen Polyclonal
1 ABIN1894433 ELISA WB Biotin Rabbit IgG AA 13-43 Anmelden zum Anzeigen Polyclonal
1 ABIN1894434 ELISA WB FITC Rabbit IgG AA 13-43 Anmelden zum Anzeigen Polyclonal
1 ABIN1894436 ELISA WB HRP Rabbit IgG AA 13-43 Anmelden zum Anzeigen Polyclonal
1 ABIN1894438 ELISA WB Alkaline Phosphatase (AP) Rabbit IgG AA 9-38 Anmelden zum Anzeigen Polyclonal
1 ABIN1894439 ELISA WB Biotin Rabbit IgG AA 9-38 Anmelden zum Anzeigen Polyclonal
1 ABIN1894441 ELISA WB PE Rabbit IgG AA 9-38 Anmelden zum Anzeigen Polyclonal

General

Antigen Coagulation Factor XII (Hageman Factor) (F12) Antikörper
Epitop AA 191-301
(22), (16), (15), (7), (6), (5), (4), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(154), (34), (29), (2), (1)
Wirt Maus
(91), (29), (24), (18), (1)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Unkonjugiert
(12), (9), (8), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation ELISA, Western Blotting (WB)
(107), (87), (21), (21), (11), (9), (9), (5), (5), (4), (4), (2), (2), (2), (2), (2), (1), (1), (1)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Spezifität F12 (AAH12390, 191 a.a. ~ 301 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Reinigung This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Immunogen F12 (AAH12390, 191 a.a. ~ 301 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Klon 3A3
Isotyp IgG2a kappa

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung F12 (F12 Antibody Abstract)
Hintergrund Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molekulargewicht 67818 DA
Gen-ID 12406
Forschungsgebiet Cell Structure
Pathways Komplementsystem

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikationshinweise ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Kommentare

Background: This gene encodes coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF)-like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa. The active factor XIIa participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. It activates coagulation factors VII and XI. Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged.

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Referenzen Bilder zurück nach oben
Buffer PBS with 0.09% (w/v) sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Haltbarkeit 6 months

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Corral, Antón, Quiroga, González-Conejero, Pereira, Roldán, Vicente, Mezzano: "Influence of the F12 -4 C>T polymorphism on hemostatic tests." in: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, Vol. 21, Issue 7, pp. 632-9, 2010

Romero, Friel, Velez Edwards, Kusanovic, Hassan, Mazaki-Tovi, Vaisbuch, Kim, Erez, Chaiworapongsa, Pearce, Bartlett, Salisbury, Anant, Vovis, Lee, Gomez, Behnke, Oyarzun, Tromp, Williams, Menon: "A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM)." in: American journal of obstetrics and gynecology, Vol. 203, Issue 4, pp. 361.e1-361.e30, 2010

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010

Antón, González-Conejero, Roldán, Quiroga, Sánchez-Vega, Corral, Vicente, Mezzano: "Study of 18 functional hemostatic polymorphisms in mucocutaneous bleeding disorders." in: Annals of hematology, Vol. 89, Issue 11, pp. 1147-54, 2010

Romero, Velez Edwards, Kusanovic, Hassan, Mazaki-Tovi, Vaisbuch, Kim, Chaiworapongsa, Pearce, Friel, Bartlett, Anant, Salisbury, Vovis, Lee, Gomez, Behnke, Oyarzun, Tromp, Williams, Menon: "Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes." in: American journal of obstetrics and gynecology, Vol. 202, Issue 5, pp. 431.e1-34, 2010

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
ELISA image for anti-Coagulation Factor XII (Hageman Factor) (F12) (AA 191-301) antibody (ABIN395773) Detection limit for recombinant GST tagged F12 is approximately 0.03 ng/mL as a captu...