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anti-Complement Factor H (CFH) Antikörper

Bezeichnung:
anti-Complement Factor H Antikörper (CFH)
Auf www.antikoerper-online.de finden Sie aktuell 264 Complement Factor H (CFH) Antikörper von 27 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Complement Factor H Kits (53) und Complement Factor H Proteine (20) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 346 Complement Factor H Produkte verfügbar.
Synonyme:
AHUS1, AMBP1, ARMD4, ARMS1, CFH, CFHL3, fH, FHL1, HF, HF1, HF2, HUS, im:7147412, Mud-1, NOM, Sas-1, Sas1, si:ch211-207o17.2

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anti-Mouse (Murine) Complement Factor H Antikörper:

anti-Human Complement Factor H Antikörper:

anti-Rat (Rattus) Complement Factor H Antikörper:

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Am meisten referenzierte anti-Complement Factor H Antikörper

  1. Human Monoclonal Complement Factor H Primary Antibody für FACS - ABIN2660858 : Ripoche, Day, Harris, Sim: The complete amino acid sequence of human complement factor H. in The Biochemical journal 1988 (PubMed)
    Zeige alle 6 Referenzen für ABIN2660858

  2. Human Polyclonal Complement Factor H Primary Antibody für EIA, IF - ABIN951646 : Dieterich, Hammerschmidt, Richter, Skerka, Wallich, Matuschka, Zipfel, Kraiczy: Inadequate binding of immune regulator factor H is associated with sensitivity of Borrelia lusitaniae to human complement. in Infection and immunity 2010 (PubMed)
    Zeige alle 3 Referenzen für ABIN951646

  3. Human Monoclonal Complement Factor H Primary Antibody für EIA, FACS - ABIN181114 : Alexander, Quigg: The simple design of complement factor H: Looks can be deceiving. in Molecular immunology 2006 (PubMed)
    Zeige alle 2 Referenzen für ABIN181114

  4. Human Polyclonal Complement Factor H Primary Antibody für IF, IHC (p) - ABIN654896 : Scambi, La Verde, De Franceschi, Barausse, Poli, Benedetti, Sorio, Deriu, Roncada, Bortolami, Turrini, Caramaschi, Stranieri, Bambara, Biasi: Comparative proteomic analysis of serum from patients with systemic sclerosis and sclerodermatous GVHD. Evidence of defective function of factor H. in PLoS ONE 2010 (PubMed)
    Zeige alle 2 Referenzen für ABIN654896

  5. Horse (Equine) Polyclonal Complement Factor H Primary Antibody für EIA, ID - ABIN113017 : Chung, Liszewski, Nybakken, Davis, Townsend, Fremont, Atkinson, Diamond: West Nile virus nonstructural protein NS1 inhibits complement activation by binding the regulatory protein factor H. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)

  6. Human Polyclonal Complement Factor H Primary Antibody für ELISA, WB - ABIN250548 : Klein, Zeiss, Chew, Tsai, Sackler, Haynes, Henning, SanGiovanni, Mane, Mayne, Bracken, Ferris, Ott, Barnstable, Hoh: Complement factor H polymorphism in age-related macular degeneration. in Science (New York, N.Y.) 2005 (PubMed)

Weitere Antikörper gegen Complement Factor H Interaktionspartner

Chimpanzee Complement Factor H (CFH) Interaktionspartner

  1. interaction between sialylated Neisseria gonorrhoeae and factor H [factor H]

Zebrafish Complement Factor H (CFH) Interaktionspartner

  1. Results report the molecular cloning and identification of complement factor H and complement factor H-like 1-4 (CFHL1 (zeige CFHR1 Antikörper)-4) in Danio rerio.

Mouse (Murine) Complement Factor H (CFH) Interaktionspartner

  1. absence of plasma CfH conferred susceptibility to glomerulonephritis

  2. This new understanding of the complicated interactions of CFH in AMD (zeige AMD1 Antikörper)-like pathology provides an improved foundation for the development of targeted therapies for AMD (zeige AMD1 Antikörper)

  3. data suggest that altered interactions of Cfh with MDA-modified proteins may be relevant in explaining the effects of the Cfh variant.

  4. Cfh and Cfhr2 (zeige CFHR2 Antikörper) genes are expressed in the mouse outer retina. Only Cfh mRNA was detected in the retinal pigment epithelium, but no protein.

  5. A spectrum of complement dysregulation was modeled on the APOE4 age related macular degeneration mouse model by crossing these mice to complement factor H knockout (cfh-/-) mice to test the impact of excess complement activation.

  6. Data indicate that co-deficiency of factor H (FH) and MASP-1/MASP-3 (zeige MASP1 Antikörper) did not ameliorate either the plasma Complement C3 (zeige C3 Antikörper) (C3) activation or glomerular C3 accumulation in FH-deficient mice.

  7. A2E accumulation altered retinal microglial complement regulation by decreasing complement factor H (and increasing complement factor B (zeige CFB Antikörper) expression), favoring increased complement activation and lipofuscin deposition in the outer retina.

  8. The exaggerated humoral immune response in CFH(-/-) mice was normalized in CFH(-/-)C5aR (zeige C5AR1 Antikörper)(-/-) double knockout mice, highlighting the C5aR (zeige C5AR1 Antikörper) dependence.

  9. Properdin (zeige CFB Antikörper) deficiency exacerbated renal injury in mice lacking complement factor H.

  10. IL-27 (zeige IL27 Antikörper) regulates complement activation through up-regulation of complement factor H in the retina.

Human Complement Factor H (CFH) Interaktionspartner

  1. CFH, ARMS2 (zeige ARMS2 Antikörper), and C3 were associated with specific features of neovascularization at the time patients were enrolled in Comparison of Age-Related Macular Degeneration Treatments Trials .

  2. Even pathogens can exploit factor H. In fact, the ability to bind factor H discriminates most pathogenic microbes from nonpathogenic ones.

  3. Moreover, the binding of Escherichia coli OmpW to human factor H, a major inhibitor of alternative complement pathway, was found, indicating that OmpW recruitment of factor H is a mechanism for bacterial evasion of complement attack.

  4. Subfoveal choroidal thickness and choroidal vascular hyperpermeability in eyes with treatment-naive polypoidal choroidal vasculopathy were associated with ARMS2 (zeige ARMS2 Antikörper) A69S (rs10490924) and CFH (rs1329428).

  5. The principal CFH genotypes that induce liver-kidney yin-deficiency age-related macular degeneration (AMD (zeige AMD1 Antikörper)) are the mutant homozygote CC and heterozygote TC forms. Moreover, C allele carriers are at higher risk of developing this disease.

  6. The results of western blotting revealed that the protein expression levels of FH and FHL1 (zeige FHL1 Antikörper) were not regulated by IL6 (zeige IL6 Antikörper) and IL8 (zeige IL8 Antikörper) in a dosedependent manner. Immunofluorescence analysis confirmed that the A2780 ovarian cancer cell line expressed both membrane bound and intracellular forms of FH and FHL1 (zeige FHL1 Antikörper).

  7. CFH Y402H SNP might be protective for AMD in the Turkish population. VEGF rs2146323 and rs699947 SNPs have no relationship to exudative AMD formation, and none of these seem to have any effect on anti-VEGF response.

  8. AG genotype of CCL2 (zeige CCL2 Antikörper)-2518 in combination with TT genotype of CFH Y402H showed significant protective effect against age-related macular degeneration.

  9. The polymorphism rs1061170/Y402H might be a genetic predictor of treatment response to anti-VEGF (zeige VEGFA Antikörper) therapy in AMD (zeige AMD1 Antikörper) patients.

  10. In this article, the authors investigated the use of complement inhibitor factor H (FH) on complement activation and showed good efficacy. The results would therefore suggest the potential application of complement inhibitor in the future

Pig (Porcine) Complement Factor H (CFH) Interaktionspartner

Complement Factor H (CFH) Antigen-Profil

Beschreibung des Gens

This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alternative names and synonyms associated with Complement Factor H (CFH)

  • complement factor H (CFH) Antikörper
  • complement factor H (cfh) Antikörper
  • complement component factor h (Cfh) Antikörper
  • complement factor H (Cfh) Antikörper
  • AHUS1 Antikörper
  • AMBP1 Antikörper
  • ARMD4 Antikörper
  • ARMS1 Antikörper
  • CFH Antikörper
  • CFHL3 Antikörper
  • fH Antikörper
  • FHL1 Antikörper
  • HF Antikörper
  • HF1 Antikörper
  • HF2 Antikörper
  • HUS Antikörper
  • im:7147412 Antikörper
  • Mud-1 Antikörper
  • NOM Antikörper
  • Sas-1 Antikörper
  • Sas1 Antikörper
  • si:ch211-207o17.2 Antikörper

Bezeichner auf Proteinebene für CFH

complement factor H , complement factor H related protein 3A4/5G4 , protein beta-1-H , H factor 1 (complement) , H factor 2 (complement) , adrenomedullin binding protein , age-related maculopathy susceptibility 1 , beta-1-H-globulin , beta-1H , factor H , factor H-like 1 , complement component factor H , complement inhibitory factor H , platelet complement factor H , complement regulator factor H

GENE ID SPEZIES
457601 Pan troglodytes
553060 Danio rerio
553297 Danio rerio
100399888 Callithrix jacchus
100451270 Pongo abelii
100465619 Ailuropoda melanoleuca
100600041 Nomascus leucogenys
12628 Mus musculus
3075 Homo sapiens
100051358 Equus caballus
155012 Rattus norvegicus
478952 Canis lupus familiaris
100733902 Cavia porcellus
100340175 Oryctolagus cuniculus
397525 Sus scrofa
280816 Bos taurus
429057 Gallus gallus
100174982 Ovis aries
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