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Human C5A ELISA Kit für Sandwich ELISA - ABIN414444
Denny, Coulthard, Finnell, Callaway, Taylor, Woodruff: Elevated complement factor C5a in maternal and umbilical cord plasma in preeclampsia. in Journal of reproductive immunology 2013
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Human C5A ELISA Kit für Sandwich ELISA - ABIN2690553
Bokisch, Müller-Eberhard: Anaphylatoxin inactivator of human plasma: its isolation and characterization as a carboxypeptidase. in The Journal of clinical investigation 1971
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Rat (Rattus) C5A ELISA Kit für Sandwich ELISA - ABIN416133
Recknagel, Bindl, Wehner, Göckelmann, Wehrle, Gebhard, Huber-Lang, Claes, Ignatius: Conversion from external fixator to intramedullary nail causes a second hit and impairs fracture healing in a severe trauma model. in Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2013
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Mouse (Murine) C5A ELISA Kit für Sandwich ELISA - ABIN415414
Woehrl, Brouwer, Murr, Heckenberg, Baas, Pfister, Zwinderman, Morgan, Barnum, van der Ende, Koedel, van de Beek: Complement component 5 contributes to poor disease outcome in humans and mice with pneumococcal meningitis. in The Journal of clinical investigation 2011
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Human C5A ELISA Kit für Sandwich ELISA - ABIN1114348
Wu, Wang, Qin, Wang, Wang, Yang, Zheng, Wang: CD55 limits sensitivity to complement-dependent cytolysis triggered by heterologous expression of ?-gal xenoantigen in colon tumor cells. in American journal of physiology. Gastrointestinal and liver physiology 2014
Mouse (Murine) C5A ELISA Kit für Sandwich ELISA - ABIN366388
Tang, Xue, Yan, Xiang, Sun, Zhao: Heparin-like surface modification of polyethersulfone membrane and its biocompatibility. in Journal of colloid and interface science 2012
Human C5A ELISA Kit für Sandwich ELISA - ABIN365042
Nie, Ma, Cheng, Deng, Zhao: Nanofibrous heparin and heparin-mimicking multilayers as highly effective endothelialization and antithrombogenic coatings. in Biomacromolecules 2015
Mouse (Murine) C5A ELISA Kit für Sandwich ELISA - ABIN1979368
Kang, Tsolmon, Mann, Zheng, Zhao, Zhao, Volk, Lokesh, Morris, Gupta, Razaq, Rui, Suh, Gorenstein, Tanaka: Safety evaluation of intravenously administered mono-thioated aptamer against E-selectin in mice. in Toxicology and applied pharmacology 2015
The complement activation factors Bb, C3a, C5a, and MAC were increased significantly in early-onset severe pre-eclampsia (EOSPE) (all P<.01) and late-onset severe pre-eclampsia (LOSPE). (P value: .027, <.001, .001, and <.001, respectively) compared with E/L-control. C1q and C4d were increased significantly in LOSPE (P value: .003 and .014, respectively) compared with L-control.
C5a/C5aR pathway promotes gastric cancer pathogenesis by suppressing p21 (zeige CDKN1A ELISA Kits)/p-p21 (zeige CDKN1A ELISA Kits) expression via activation of PI3K (zeige PIK3CA ELISA Kits)/AKT (zeige AKT1 ELISA Kits) signaling.
Studies indicate that the complement response lie the active fragments, C3a (zeige C3 ELISA Kits) and C5a, acting through their specific receptors, C3aR (zeige C3AR1 ELISA Kits), C5aR1 (zeige C5AR1 ELISA Kits) and C5aR2 to direct the cellular response to inflammation.
Data show the expression of a neoepitope which was exposed on complement C5 (zeige C5 ELISA Kits) (C5) after binding to eculizumab in vivo.
data indicate that properdin enhances platelet/granulocyte aggregates (PGAs) formation via increased production of C5a, and that inhibition of properdin function has therapeutic potential to limit thromboinflammation in diseases characterized by increased PGA formation
Increased C5a expression is associated with increased inflammation in cystic fibrosis (zeige S100A8 ELISA Kits).
In an arterial thrombosis model, plasminogen activator administration increased C5a levels. Overall, these findings suggest plasmin bridges thrombosis and the immune response by liberating C5a and inducing MAC assembly.
C5 rs2269067 GG genotype confers risk for proliferative diabetic retinopathy of type 2 diabetes in Chinese Han population (associated with an elevated C5 mRNA expression and an increased IL-6 (zeige IL6 ELISA Kits) production)
The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to a susceptibility to liver fibrosis and to rheumatoid arthritis.
C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4
, C5a anaphylatoxin
, anaphylatoxin C5a analog
, complement C5