anti-Ratte (Rattus) Complement Component 5 Antikörper für Immunohistochemistry (Paraffin-embedded Sections)

Recommended Complement Component 5 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Complement Component 5 (C5) Antikörper
  • C5
  • LOC565774
  • C5a
  • C5b
  • CPAMD4
  • Hc
  • RGD1561905
  • He
  • complement component 5
  • similar to complement component C5-1
  • hemolytic complement
  • C5
  • LOC565774
  • Hc
Epitop
AA 1-18, N-Term
23
15
13
7
6
3
2
2
1
1
1
1
1
Reaktivität
Maus, Ratte (Rattus)
146
21
10
6
2
2
2
1
Wirt
Kaninchen
85
76
11
6
Klonalität
Polyklonal
Konjugat
Unkonjugiert
14
12
6
6
5
4
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
104
82
28
22
18
16
13
10
10
9
9
7
6
5
4
3
2
2
2
2
1
1
1
1
Optionen
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Bilder

Produktnummer ABIN3044294
$ 200.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN3043765 IHC (p) WB Rabbit IgG AA 1-77 Anmelden zum Anzeigen Polyclonal
1 ABIN2619444 IHC (p) WB Rabbit IgG AA 1-77 Anmelden zum Anzeigen Polyclonal
1 ABIN2619442 IHC (p) WB Rabbit IgG AA 1-18 Anmelden zum Anzeigen Polyclonal
1 ABIN3029691 IHC (p) WB Rabbit IgG AA 1-77 Anmelden zum Anzeigen Polyclonal

General

Antigen Complement Component 5 (C5) Antikörper
Epitop AA 1-18, N-Term
(23), (15), (13), (7), (6), (3), (2), (2), (1), (1), (1), (1), (1)
Reaktivität Maus, Ratte (Rattus)
(146), (21), (10), (6), (2), (2), (2), (1)
Wirt Kaninchen
(85), (76), (11), (6)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(14), (12), (6), (6), (5), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(104), (82), (28), (22), (18), (16), (13), (10), (10), (9), (9), (7), (6), (5), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Bilder
Verwendungszweck Rabbit IgG polyclonal antibody for Complement C5(C5) detection. Tested with WB, IHC-P in Mouse,Rat.
Sequenz DLQLLHQKVE EQAAKYKH
Kreuzreaktivität (Details) No cross reactivity with other proteins.
Produktmerkmale Rabbit IgG polyclonal antibody for Complement C5(C5) detection. Tested with WB, IHC-P in Mouse,Rat.
Gene Name: complement component 5
Protein Name: Complement C5
Reinigung Immunogen affinity purified.
Immunogen A synthetic peptide corresponding to a sequence at the N-terminus of rat C5a(1-18aa DLQLLHQKVEEQAAKYKH), different from the related mouse sequence by four amino acids.
Isotyp IgG

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Complement C5 (C5 Antibody Abstract)
Hintergrund C5a is a protein fragment released from complement component C5. This gene is mapped to 9q33.2. The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to susceptibility to liver fibrosis and to rheumatoid arthritis.

Synonyms: Anaphylatoxin C5a analog antibody|Anaphylatoxin C5a antibody|C5 antibody|C5a antibody|Complement C5 antibody|Complement component C5 antibody|Complement component C5a antibody|CPAMD 4 antibody|CPAMD4 antibody
Gen-ID 362119
UniProt P08650
Forschungsgebiet Complement Factors, Innate Immunity
Pathways Komplementsystem, Carbohydrate Homeostasis

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Bilder zurück nach oben
Applikationshinweise WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Kommentare

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Bilder zurück nach oben
Format Lyophilized
Rekonstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Konzentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Konservierungsmittel Thimerosal (Merthiolate), Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Complement Component 5 (C5) (AA 1-18), (N-Term) antibody (ABIN3044294) anti-Complement Component 5 (C5) (AA 1-18), (N-Term) antibody
Immunohistochemistry (IHC) image for anti-Complement Component 5 (C5) (AA 1-18), (N-Term) antibody (ABIN3044294) Anti-C5/C5a antibody, IHC(P) IHC(P): Mouse Spleen Tissue
Western Blotting (WB) image for anti-Complement Component 5 (C5) (AA 1-18), (N-Term) antibody (ABIN3044294) anti-Complement Component 5 (C5) (AA 1-18), (N-Term) antibody (Image 3)
Immunohistochemistry (IHC) image for anti-Complement Component 5 (C5) (AA 1-18), (N-Term) antibody (ABIN3044294) Anti-C5/C5a antibody, IHC(P) IHC(P): Rat Spleen Tissue
Immunohistochemistry (IHC) image for anti-Complement Component 5 (C5) (AA 1-18), (N-Term) antibody (ABIN3044294) Anti-C5/C5a antibody, IHC(P) IHC(P): Rat Liver Tissue